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The map label for this gene is cnrB [H]

Identifier: 103487268

GI number: 103487268

Start: 1882384

End: 1883958

Strand: Reverse

Name: cnrB [H]

Synonym: Sala_1784

Alternate gene names: 103487268

Gene position: 1883958-1882384 (Counterclockwise)

Preceding gene: 103487269

Following gene: 103487267

Centisome position: 56.32

GC content: 67.05

Gene sequence:

>1575_bases
ATGAATCCGTGCCGCACGACCATTGATGCCCTCTCGATCCGAGTATTGATAATGACCCGATCTCGCCTGCTTGCGGCGCT
TGCCGCACCTGTTCTGGCCCTGTCCTTGGCAGGGTGCGGATTGCTGTCCCCGGACGAACAGGCGGAGGCTGATGGCGGCG
GCGGGATCGTGGTCACGCATTTTGCACCTTCGACCGAGCTGTTCGTCGAATACCGCCCCTTGGTGCAGGGCAAGGACCGG
CGGTTCGATGCGCATCTCACCTGGCTCGACAGCTACAAGCCGGTGACCGATGGCACGCTGACCGCCGAACTGGTGTGGCC
CGATGGCACGATAGACACGGCCAAGGCCGGGCCGAGCGACGTCCAGGGCATCTTCAGACCGCTGCTGAAGGCGTCCAAAA
GCGGCAAGGCGCGGCTGCGCTTGGTGCTGGGCAACCCCAAGGGTCAATCGGTTCACGATCTGGGCGAGGTCACCGTGTGG
GCCACGAGCGCAGAAGGCGCCAAGGCCGCTCCCGCCGAAGCCGAGGAGGAAGGCGCGGTCGCTTTCTCCAAGGAAGTGCA
ATGGCGCATCCCGTTCATGACCACGGCGGCGCAGGTCACCAATTTTGCCGAGACAGTGCCGGTCACTGTCGATGTCCAGA
TCCAGCCCCAGGCCGAAGCGATTGTTTCAGCTCCGGTCGACGGCATTCTGCGCGCGGCGAGGATGCCTGCTGCGGGCGAC
CGGGTGCGGCGCGGGCAGGTGCTCGCCAGCATTTCTTCCACTCTGGGTGGCGGCGAGGATGTTGCGACCCTTGATCTTGC
CATCAACGAAGCGCGGATCGCCCGCGATGCGGCCGCGCGCGAAGTCGCACGCATGACGCAGCTGGTCGAAGCCGAAGCCG
TGCCGGCACGGCGGCTCGATGAAGCGCGCACCGCGTTGCGGATGGCTGAGGCGCAATTGCGGTCGGCTAGTCAGCGCCGT
TCAGCTGTGGCAGGCGGCGGCGCGGGCGTGCCGGTGGTTGCCCCAATCTCCGGGGAGGTGCTCGATAGCGCCCTGGTGCA
AGGCGCGGGCGTCACCGGCGGACAACGCTTGTTGCGGATCGGCGATCCAGCGGCGCTGTGGCTGGTTGCCCGTGTGCCCG
AAGCAATGGCGGCCATGGTCGGGACACCCAACGGGATCGACCTGCAACTGCCCGATCGGGTGATCACGCTTGGCGATGGC
ACCGGCCAGCTGGTGCAGCGCGGTGCGGCGATTGACCCACAGACCCGCACCCTTTCGGTGATCTATGCCTGGAACAGCCG
CGCACTGCGCCCCGGCCAGCGGGTGCAGGGACTGCTGCGCACCGGCTATGCGACACGGCGGCTGACCATTCCGGCCAGCG
CCTTGCTCAACGAAAGCGGGCAGGATGTAGTCTACGTGCAGCTCGGCGGCGAAACCTTCCAGCGCCGCGCGGTCACCGTG
CTGGCGCGTAGCGGCACTCGGGTGGCGATAGAAGGCCAGCTCAAAGCAGGCGAACGGGTGGTCACGCGCGGTGCGGCGGC
GGTCAGAGCAGCAGCGGCGACGCCCGATGCTTTCGGCCACGGCCATGCGCATTGA

Upstream 100 bases:

>100_bases
GCCGACACCGCCGAAGCGCCCGAAGCTGCGCCTGAAGCAGACGATGATAACGACGCACCCGAACCCGTCGCCGAAGCCCA
CGACGAGGACGAGCCGCACG

Downstream 100 bases:

>100_bases
GGGGCGGCACTGTGCTTGAACGCCTCGTCCGCTGGAGCCTTGAAAACCGCGCCATCGTTTATGCCATCGCTGCGCTGCTG
ACCGCGTTCGGCGCTTGGAC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MNPCRTTIDALSIRVLIMTRSRLLAALAAPVLALSLAGCGLLSPDEQAEADGGGGIVVTHFAPSTELFVEYRPLVQGKDR
RFDAHLTWLDSYKPVTDGTLTAELVWPDGTIDTAKAGPSDVQGIFRPLLKASKSGKARLRLVLGNPKGQSVHDLGEVTVW
ATSAEGAKAAPAEAEEEGAVAFSKEVQWRIPFMTTAAQVTNFAETVPVTVDVQIQPQAEAIVSAPVDGILRAARMPAAGD
RVRRGQVLASISSTLGGGEDVATLDLAINEARIARDAAAREVARMTQLVEAEAVPARRLDEARTALRMAEAQLRSASQRR
SAVAGGGAGVPVVAPISGEVLDSALVQGAGVTGGQRLLRIGDPAALWLVARVPEAMAAMVGTPNGIDLQLPDRVITLGDG
TGQLVQRGAAIDPQTRTLSVIYAWNSRALRPGQRVQGLLRTGYATRRLTIPASALLNESGQDVVYVQLGGETFQRRAVTV
LARSGTRVAIEGQLKAGERVVTRGAAAVRAAAATPDAFGHGHAH

Sequences:

>Translated_524_residues
MNPCRTTIDALSIRVLIMTRSRLLAALAAPVLALSLAGCGLLSPDEQAEADGGGGIVVTHFAPSTELFVEYRPLVQGKDR
RFDAHLTWLDSYKPVTDGTLTAELVWPDGTIDTAKAGPSDVQGIFRPLLKASKSGKARLRLVLGNPKGQSVHDLGEVTVW
ATSAEGAKAAPAEAEEEGAVAFSKEVQWRIPFMTTAAQVTNFAETVPVTVDVQIQPQAEAIVSAPVDGILRAARMPAAGD
RVRRGQVLASISSTLGGGEDVATLDLAINEARIARDAAAREVARMTQLVEAEAVPARRLDEARTALRMAEAQLRSASQRR
SAVAGGGAGVPVVAPISGEVLDSALVQGAGVTGGQRLLRIGDPAALWLVARVPEAMAAMVGTPNGIDLQLPDRVITLGDG
TGQLVQRGAAIDPQTRTLSVIYAWNSRALRPGQRVQGLLRTGYATRRLTIPASALLNESGQDVVYVQLGGETFQRRAVTV
LARSGTRVAIEGQLKAGERVVTRGAAAVRAAAATPDAFGHGHAH
>Mature_524_residues
MNPCRTTIDALSIRVLIMTRSRLLAALAAPVLALSLAGCGLLSPDEQAEADGGGGIVVTHFAPSTELFVEYRPLVQGKDR
RFDAHLTWLDSYKPVTDGTLTAELVWPDGTIDTAKAGPSDVQGIFRPLLKASKSGKARLRLVLGNPKGQSVHDLGEVTVW
ATSAEGAKAAPAEAEEEGAVAFSKEVQWRIPFMTTAAQVTNFAETVPVTVDVQIQPQAEAIVSAPVDGILRAARMPAAGD
RVRRGQVLASISSTLGGGEDVATLDLAINEARIARDAAAREVARMTQLVEAEAVPARRLDEARTALRMAEAQLRSASQRR
SAVAGGGAGVPVVAPISGEVLDSALVQGAGVTGGQRLLRIGDPAALWLVARVPEAMAAMVGTPNGIDLQLPDRVITLGDG
TGQLVQRGAAIDPQTRTLSVIYAWNSRALRPGQRVQGLLRTGYATRRLTIPASALLNESGQDVVYVQLGGETFQRRAVTV
LARSGTRVAIEGQLKAGERVVTRGAAAVRAAAATPDAFGHGHAH

Specific function: The products of the genes cnrA, cnrB, and cnrC are likely to form a membrane-bound protein complex catalyzing an energy-dependent efflux of Ni(2+) and Co(2+). The mechanism of action of the CnrCBA complex may be that of a proton/cation antiporter [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 54911; Mature: 54911

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPCRTTIDALSIRVLIMTRSRLLAALAAPVLALSLAGCGLLSPDEQAEADGGGGIVVTH
CCCHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEE
FAPSTELFVEYRPLVQGKDRRFDAHLTWLDSYKPVTDGTLTAELVWPDGTIDTAKAGPSD
ECCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCHH
VQGIFRPLLKASKSGKARLRLVLGNPKGQSVHDLGEVTVWATSAEGAKAAPAEAEEEGAV
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCE
AFSKEVQWRIPFMTTAAQVTNFAETVPVTVDVQIQPQAEAIVSAPVDGILRAARMPAAGD
EEECCCEEEECEEHHHHHHHHHHHHCCEEEEEEECCCHHHHHHCCHHHHHHHHCCCCCCC
RVRRGQVLASISSTLGGGEDVATLDLAINEARIARDAAAREVARMTQLVEAEAVPARRLD
HHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EARTALRMAEAQLRSASQRRSAVAGGGAGVPVVAPISGEVLDSALVQGAGVTGGQRLLRI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCEEEEE
GDPAALWLVARVPEAMAAMVGTPNGIDLQLPDRVITLGDGTGQLVQRGAAIDPQTRTLSV
CCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECCCCHHHHHCCCCCCCCCCEEEE
IYAWNSRALRPGQRVQGLLRTGYATRRLTIPASALLNESGQDVVYVQLGGETFQRRAVTV
EEEECCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHCCCCCEEEEEEECCHHHHHHEEEE
LARSGTRVAIEGQLKAGERVVTRGAAAVRAAAATPDAFGHGHAH
EECCCCEEEEECCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNPCRTTIDALSIRVLIMTRSRLLAALAAPVLALSLAGCGLLSPDEQAEADGGGGIVVTH
CCCHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEE
FAPSTELFVEYRPLVQGKDRRFDAHLTWLDSYKPVTDGTLTAELVWPDGTIDTAKAGPSD
ECCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCHH
VQGIFRPLLKASKSGKARLRLVLGNPKGQSVHDLGEVTVWATSAEGAKAAPAEAEEEGAV
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCE
AFSKEVQWRIPFMTTAAQVTNFAETVPVTVDVQIQPQAEAIVSAPVDGILRAARMPAAGD
EEECCCEEEECEEHHHHHHHHHHHHCCEEEEEEECCCHHHHHHCCHHHHHHHHCCCCCCC
RVRRGQVLASISSTLGGGEDVATLDLAINEARIARDAAAREVARMTQLVEAEAVPARRLD
HHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EARTALRMAEAQLRSASQRRSAVAGGGAGVPVVAPISGEVLDSALVQGAGVTGGQRLLRI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCEEEEE
GDPAALWLVARVPEAMAAMVGTPNGIDLQLPDRVITLGDGTGQLVQRGAAIDPQTRTLSV
CCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECCCCHHHHHCCCCCCCCCCEEEE
IYAWNSRALRPGQRVQGLLRTGYATRRLTIPASALLNESGQDVVYVQLGGETFQRRAVTV
EEEECCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHCCCCCEEEEEEECCHHHHHHEEEE
LARSGTRVAIEGQLKAGERVVTRGAAAVRAAAATPDAFGHGHAH
EECCCCEEEEECCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8380802; 10671463 [H]