Click here to switch to the map view.

The map label for this gene is ywlC [H]

Identifier: 103487254

GI number: 103487254

Start: 1864963

End: 1865910

Strand: Reverse

Name: ywlC [H]

Synonym: Sala_1769

Alternate gene names: 103487254

Gene position: 1865910-1864963 (Counterclockwise)

Preceding gene: 103487257

Following gene: 103487251

Centisome position: 55.78

GC content: 71.62

Gene sequence:

>948_bases
ATGGCCGAAGGCTCAAAGTCCACAATTGTTCGCGCGTTCGATAGCGCGGCGATCGCCGAGGCGGCGGCGCTGATCGCGGG
CGGGCAGCCGGTCGCGGTGCCGACCGAGACGGTATACGGGCTTGCCGCCGATGCGCGGAGCGCCGACGGCGTCGCGCGCA
TCTATGCCGCGAAGGGGCGCCCCGATTTCAATCCGCTGATCGTCCATGTGCCGAACCTTGCTGCGGCGGAGACGCTGGGA
CAGTTCGGCGCCGCCGAACGTGCGCTCGCGACGCGCTTCTGGCCGGGACCGCTGACCCTGGTGGTGCCGCGCGTGGCCGG
ATGCCCGGTCGCCAGCATCGCGACCGCGGGGCTCGACACGATTGCCCTCAGGGTGCCGGGGCATCGCGCGATGCAGGCCT
TGCTGGCGGGCACGGGCGCCCCGCTCGCGGCGCCGAGCGCCAATGCGAGCGGGCGCGTGAGCCCGACAAGGGCGGACCAT
GTGCTTGCGAGCCTCGATGGCCGGATCGCGCTGGTGATCGACGACGGGCCGACGCGCGCGGGGGTCGAATCGACGATTGC
GCGCGTCCAGGACGGCGCGATCGAAGTGTTGCGGCCGGGGCCGGTTACGGCGGCGATGCTGGCGATGGCGAGCGGATTGC
CGGTGATCGAGCGCAAGGGGTCGGACATCGTCGCGCCGGGAATGCTGGCGAGCCATTATGCGCCGGGCAAGCCGGTGCGG
CTGGGCGCGGTCGAGTTTGCGGATGACGAGTTCGGGATCGGGTTTGGGGGGCTCGCTGGCGATTATGACCTGAGCGCGGC
GGGCGATCTGACCGAGGCGGCGGCGCGGCTTTTCGACGCGCTGCACGCGGGGGCAGCGAGCGCAAAGCCGAACATTGCGG
TGGCGGCGATACCGGTGGAAGGGCTGGGCGCGGCGATCAACGACCGGTTGGCGAGGGCCGCGGTCTAG

Upstream 100 bases:

>100_bases
ATGATTGAGGACGAAGAGCTGTTCGGCGGTGGGCGGCGTGTAGGTCATGCGATGGCCGACTTTCTTGATGAATCTCGTTG
CGCGGGCGCTATAGCGCGGC

Downstream 100 bases:

>100_bases
GCTGTATCGACTTCAGCTCTGGTGGCTTTCCGCGCTTCCGCTGCTCACGTCCCATCAGCATGCTGCGCGCCGGGGAGCGG
GCGCGCCCGCCATATTGTCG

Product: Sua5/YciO/YrdC/YwlC

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MAEGSKSTIVRAFDSAAIAEAAALIAGGQPVAVPTETVYGLAADARSADGVARIYAAKGRPDFNPLIVHVPNLAAAETLG
QFGAAERALATRFWPGPLTLVVPRVAGCPVASIATAGLDTIALRVPGHRAMQALLAGTGAPLAAPSANASGRVSPTRADH
VLASLDGRIALVIDDGPTRAGVESTIARVQDGAIEVLRPGPVTAAMLAMASGLPVIERKGSDIVAPGMLASHYAPGKPVR
LGAVEFADDEFGIGFGGLAGDYDLSAAGDLTEAAARLFDALHAGAASAKPNIAVAAIPVEGLGAAINDRLARAAV

Sequences:

>Translated_315_residues
MAEGSKSTIVRAFDSAAIAEAAALIAGGQPVAVPTETVYGLAADARSADGVARIYAAKGRPDFNPLIVHVPNLAAAETLG
QFGAAERALATRFWPGPLTLVVPRVAGCPVASIATAGLDTIALRVPGHRAMQALLAGTGAPLAAPSANASGRVSPTRADH
VLASLDGRIALVIDDGPTRAGVESTIARVQDGAIEVLRPGPVTAAMLAMASGLPVIERKGSDIVAPGMLASHYAPGKPVR
LGAVEFADDEFGIGFGGLAGDYDLSAAGDLTEAAARLFDALHAGAASAKPNIAVAAIPVEGLGAAINDRLARAAV
>Mature_314_residues
AEGSKSTIVRAFDSAAIAEAAALIAGGQPVAVPTETVYGLAADARSADGVARIYAAKGRPDFNPLIVHVPNLAAAETLGQ
FGAAERALATRFWPGPLTLVVPRVAGCPVASIATAGLDTIALRVPGHRAMQALLAGTGAPLAAPSANASGRVSPTRADHV
LASLDGRIALVIDDGPTRAGVESTIARVQDGAIEVLRPGPVTAAMLAMASGLPVIERKGSDIVAPGMLASHYAPGKPVRL
GAVEFADDEFGIGFGGLAGDYDLSAAGDLTEAAARLFDALHAGAASAKPNIAVAAIPVEGLGAAINDRLARAAV

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=153, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17537239, Length=161, Percent_Identity=33.5403726708075, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=267, Percent_Identity=37.4531835205993, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI78707274, Length=139, Percent_Identity=36.6906474820144, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 31462; Mature: 31331

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGSKSTIVRAFDSAAIAEAAALIAGGQPVAVPTETVYGLAADARSADGVARIYAAKGR
CCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEECCCHHHHEECCCCCCCCCEEEEEEECCC
PDFNPLIVHVPNLAAAETLGQFGAAERALATRFWPGPLTLVVPRVAGCPVASIATAGLDT
CCCCCEEEECCCHHHHHHHHHHCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCE
IALRVPGHRAMQALLAGTGAPLAAPSANASGRVSPTRADHVLASLDGRIALVIDDGPTRA
EEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCC
GVESTIARVQDGAIEVLRPGPVTAAMLAMASGLPVIERKGSDIVAPGMLASHYAPGKPVR
CHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCEEECCCCCEECCCHHHHCCCCCCCEE
LGAVEFADDEFGIGFGGLAGDYDLSAAGDLTEAAARLFDALHAGAASAKPNIAVAAIPVE
EEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECHH
GLGAAINDRLARAAV
HCCHHHHHHHHHHCC
>Mature Secondary Structure 
AEGSKSTIVRAFDSAAIAEAAALIAGGQPVAVPTETVYGLAADARSADGVARIYAAKGR
CCCCCCCEEHHHHHHHHHHHHHHHCCCCCEECCCHHHHEECCCCCCCCCEEEEEEECCC
PDFNPLIVHVPNLAAAETLGQFGAAERALATRFWPGPLTLVVPRVAGCPVASIATAGLDT
CCCCCEEEECCCHHHHHHHHHHCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCE
IALRVPGHRAMQALLAGTGAPLAAPSANASGRVSPTRADHVLASLDGRIALVIDDGPTRA
EEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCC
GVESTIARVQDGAIEVLRPGPVTAAMLAMASGLPVIERKGSDIVAPGMLASHYAPGKPVR
CHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCEEECCCCCEECCCHHHHCCCCCCCEE
LGAVEFADDEFGIGFGGLAGDYDLSAAGDLTEAAARLFDALHAGAASAKPNIAVAAIPVE
EEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECHH
GLGAAINDRLARAAV
HCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]