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The map label for this gene is fnrL [H]

Identifier: 103487163

GI number: 103487163

Start: 1765994

End: 1766686

Strand: Reverse

Name: fnrL [H]

Synonym: Sala_1678

Alternate gene names: 103487163

Gene position: 1766686-1765994 (Counterclockwise)

Preceding gene: 103487164

Following gene: 103487161

Centisome position: 52.81

GC content: 65.08

Gene sequence:

>693_bases
GTGGCCGATTGTGCGACCTGTATTGTTCGAAACCGCGCCATCTGCGCGAGCCTGAACCCCGCGGAACTGGCCGCGCTGGG
CAGGATGGGCCGCAAGCAGAAGGTGCGCGCGGGGCAGACGCTCCTGTGGGAGGGCGATGGCGCGCCAGTGGTCGCCAATG
TGCTCGAAGGCGTGCTCAAGCTTGTCGTGTCGACCGCCGACGGGCGCGAGCAGATTGTCGGCGTCGTCTTTCCGTCCGAT
TTCATCGGCCGTCCGTTCGGCAAGGAAAGTCCCTACAGCGTCACCGCGATGACCGACGCCGAAGTCTGCATCTTCAACCG
CAACAATTTCGACGAGTTTGCCGGTAGCCACCCCGATCTTCAGCAGAAATTGCTCCGCCGCACGCTCGACGAGCTCGACC
GCGCGCGGCACTGGATGATGCTGCTCGGGCGCAAGTCGGCGTCGGAAAAGGTCGCGTCCTTCCTGCTCGAAATGTCCGAG
CGGCTGGAGGGGCAGGGGTGCGGCGTCGGCCTGAACCGCGGCGCCTTCGAGCTGCCCTTCGGTCGCCAGCAGATCGCCGA
TATACTGGGACTGACGATCGAGACGACGAGCCGTCAGCTTACGAAAATGCGCGCCGACGGCGTGCTCGACCTCCCCTCGC
GCCGCGAGATCGTCATCCACGATCGCGCGGCGATGGAGGATATGGCGGGATAA

Upstream 100 bases:

>100_bases
CACGCTGCGTCCCTCTCGCGGAGCAATCCCGCTGAAACAGGGGCCAGGGTTTCGATTCGCGACGCTTTCCAAAGCCGCAG
CCTTCCTGTAGGGGGGCGCG

Downstream 100 bases:

>100_bases
AACCGCCGTTCAGAAGCGGAAGGCCGCCCCTGCGCTGACGACCCAGGGATCGAGCTTGTGCCGGGTGCGCAGCACCTCGG
TCGGCCCGGCGAACCAGCGC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MADCATCIVRNRAICASLNPAELAALGRMGRKQKVRAGQTLLWEGDGAPVVANVLEGVLKLVVSTADGREQIVGVVFPSD
FIGRPFGKESPYSVTAMTDAEVCIFNRNNFDEFAGSHPDLQQKLLRRTLDELDRARHWMMLLGRKSASEKVASFLLEMSE
RLEGQGCGVGLNRGAFELPFGRQQIADILGLTIETTSRQLTKMRADGVLDLPSRREIVIHDRAAMEDMAG

Sequences:

>Translated_230_residues
MADCATCIVRNRAICASLNPAELAALGRMGRKQKVRAGQTLLWEGDGAPVVANVLEGVLKLVVSTADGREQIVGVVFPSD
FIGRPFGKESPYSVTAMTDAEVCIFNRNNFDEFAGSHPDLQQKLLRRTLDELDRARHWMMLLGRKSASEKVASFLLEMSE
RLEGQGCGVGLNRGAFELPFGRQQIADILGLTIETTSRQLTKMRADGVLDLPSRREIVIHDRAAMEDMAG
>Mature_229_residues
ADCATCIVRNRAICASLNPAELAALGRMGRKQKVRAGQTLLWEGDGAPVVANVLEGVLKLVVSTADGREQIVGVVFPSDF
IGRPFGKESPYSVTAMTDAEVCIFNRNNFDEFAGSHPDLQQKLLRRTLDELDRARHWMMLLGRKSASEKVASFLLEMSER
LEGQGCGVGLNRGAFELPFGRQQIADILGLTIETTSRQLTKMRADGVLDLPSRREIVIHDRAAMEDMAG

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=230, Percent_Identity=29.5652173913043, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25232; Mature: 25101

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADCATCIVRNRAICASLNPAELAALGRMGRKQKVRAGQTLLWEGDGAPVVANVLEGVLK
CCHHHHHHHHCCHHEECCCHHHHHHHHHCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHH
LVVSTADGREQIVGVVFPSDFIGRPFGKESPYSVTAMTDAEVCIFNRNNFDEFAGSHPDL
HHHHCCCCHHHEEEEECCHHHHCCCCCCCCCEEEEEECCCEEEEEECCCHHHHCCCCCCH
QQKLLRRTLDELDRARHWMMLLGRKSASEKVASFLLEMSERLEGQGCGVGLNRGAFELPF
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
GRQQIADILGLTIETTSRQLTKMRADGVLDLPSRREIVIHDRAAMEDMAG
CHHHHHHHHCCHHHHHHHHHHHHHCCCCEECCCCCEEEEECHHHHHHHCC
>Mature Secondary Structure 
ADCATCIVRNRAICASLNPAELAALGRMGRKQKVRAGQTLLWEGDGAPVVANVLEGVLK
CHHHHHHHHCCHHEECCCHHHHHHHHHCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHH
LVVSTADGREQIVGVVFPSDFIGRPFGKESPYSVTAMTDAEVCIFNRNNFDEFAGSHPDL
HHHHCCCCHHHEEEEECCHHHHCCCCCCCCCEEEEEECCCEEEEEECCCHHHHCCCCCCH
QQKLLRRTLDELDRARHWMMLLGRKSASEKVASFLLEMSERLEGQGCGVGLNRGAFELPF
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
GRQQIADILGLTIETTSRQLTKMRADGVLDLPSRREIVIHDRAAMEDMAG
CHHHHHHHHCCHHHHHHHHHHHHHCCCCEECCCCCEEEEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]