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The map label for this gene is ccmE

Identifier: 103487002

GI number: 103487002

Start: 1584368

End: 1584805

Strand: Reverse

Name: ccmE

Synonym: Sala_1517

Alternate gene names: 103487002

Gene position: 1584805-1584368 (Counterclockwise)

Preceding gene: 103487003

Following gene: 103487001

Centisome position: 47.38

GC content: 65.98

Gene sequence:

>438_bases
ATGAAGGCAAAGCATCAGCGGCTGATCCTGGCGGTCGCGGCGCTGTGCGGCGTTGCGGGCGCGGGCGTGCTCGCGGCGAG
CGCGCTCCGCGACGAGGCCGCTTATTTCCGCACGCCCGTTGAAATTGCAGGCGGCAAGGCCGCGGTTGGCGAAGCGATGC
GGCTGGGCGGCATGGTTGCCAAGGGCAGTATCGTGCGCCAGGCCGACGGCCTCACGATCCGCTTCGTTGCGACCGATGGC
CAGGCGTCGGTGCCCGTCGAATATACAGGCATCGTTCCCGACCTGTTCGGCGAGGAAAGCGGCATGATCGCCGACGGACG
GATGCGCGCCGACGGGACGTTCGTTGCCGATCGTATCCTGGCGAAACATGACGAGCGTTATATGCCGCCGCAGATGGGCG
AGATGCCGAAGAATATGAAGGCGGCGGTGGAGGGATGA

Upstream 100 bases:

>100_bases
ATGGTCTGACGATCGTGCTGACGGGCGCGGTGCTGTGGTCGAGCTGGCGCGCGATGACGCGCGCCGAGAAACGCAGCGAC
GCGCTGCGGAAGGATCGCAA

Downstream 100 bases:

>100_bases
ATTGTACATCATTCCCGTCATTGCGAGCGCCGCGAAGCAATCTCCTGCGTGCGGCCTTTTACCCTGAGAGCTGGAGACTG
CTTCGTCGCTTCGCTCCTCG

Product: CcmE/CycJ protein

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKAKHQRLILAVAALCGVAGAGVLAASALRDEAAYFRTPVEIAGGKAAVGEAMRLGGMVAKGSIVRQADGLTIRFVATDG
QASVPVEYTGIVPDLFGEESGMIADGRMRADGTFVADRILAKHDERYMPPQMGEMPKNMKAAVEG

Sequences:

>Translated_145_residues
MKAKHQRLILAVAALCGVAGAGVLAASALRDEAAYFRTPVEIAGGKAAVGEAMRLGGMVAKGSIVRQADGLTIRFVATDG
QASVPVEYTGIVPDLFGEESGMIADGRMRADGTFVADRILAKHDERYMPPQMGEMPKNMKAAVEG
>Mature_145_residues
MKAKHQRLILAVAALCGVAGAGVLAASALRDEAAYFRTPVEIAGGKAAVGEAMRLGGMVAKGSIVRQADGLTIRFVATDG
QASVPVEYTGIVPDLFGEESGMIADGRMRADGTFVADRILAKHDERYMPPQMGEMPKNMKAAVEG

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=135, Percent_Identity=40, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_SPHAL (Q1GSZ2)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616563.1
- ProteinModelPortal:   Q1GSZ2
- SMR:   Q1GSZ2
- GeneID:   4080030
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1517
- NMPDR:   fig|317655.9.peg.1450
- HOGENOM:   HBG296631
- OMA:   HVEFAVH
- ProtClustDB:   CLSK846754
- BioCyc:   SALA317655:SALA_1517-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 15163; Mature: 15163

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: BINDING 123-123

Signals:

None

Transmembrane regions:

HASH(0x114a6928)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKHQRLILAVAALCGVAGAGVLAASALRDEAAYFRTPVEIAGGKAAVGEAMRLGGMVA
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHCCEEC
KGSIVRQADGLTIRFVATDGQASVPVEYTGIVPDLFGEESGMIADGRMRADGTFVADRIL
CCCEEEECCCCEEEEEEECCCCCCCEEECCCCCHHCCCCCCEEECCEECCCCHHHHHHHH
AKHDERYMPPQMGEMPKNMKAAVEG
HHCCCCCCCCCCCCCCCCCHHCCCH
>Mature Secondary Structure
MKAKHQRLILAVAALCGVAGAGVLAASALRDEAAYFRTPVEIAGGKAAVGEAMRLGGMVA
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHCCEEC
KGSIVRQADGLTIRFVATDGQASVPVEYTGIVPDLFGEESGMIADGRMRADGTFVADRIL
CCCEEEECCCCEEEEEEECCCCCCCEEECCCCCHHCCCCCCEEECCEECCCCHHHHHHHH
AKHDERYMPPQMGEMPKNMKAAVEG
HHCCCCCCCCCCCCCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA