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The map label for this gene is regB [H]

Identifier: 103486988

GI number: 103486988

Start: 1565921

End: 1567228

Strand: Reverse

Name: regB [H]

Synonym: Sala_1503

Alternate gene names: 103486988

Gene position: 1567228-1565921 (Counterclockwise)

Preceding gene: 103486989

Following gene: 103486987

Centisome position: 46.85

GC content: 70.11

Gene sequence:

>1308_bases
ATGACCGACCTTTCGATCCTGCCGCCGGCGCCCAGCACGGCGCCCGCCGGCCGCCGCAACATGGCGCTGCTGATCCAGCT
GCGCTGGCTCGCGGTGGGCGGGCAGCTGGCGACGATCGGCATCGTCAGCGGACCGATGGGCATTTCGCTCGAGCGTGCGC
CGCTGCTCGGCGCGATCCTCGTGCTCATCGCGATCAACCTCGCCAGCGCCGCCCTGCTGCGCCGCGGCCGCGCGGTGACC
AATGCCGAACTGACCGCGGCGCTGCTCTTCGATGTCGCCGCGCTTGGCTGGCAGCTCCACCATAGCGGCGGCCTCGCCAA
TCCCTTCGCGTCGCTGTTCCTGCTGCAAGTCGTGATCGGCGCGATCCTGCTCACCCCGCGCTCATCCTGGGCGATCGTGG
TCGCCGCGTTGATTGCCCTCGCGGCGCTCCGCATCGACCCGACGCCGCTCGTGCTGCCGCCCGCCTATGCCGCTGATCCG
ATGGGACTGTATCTCAAGGGCAGCTTCGTCTGCTTCCTGCTGATTGCCGTCCTGCTCGTCGCCTTCGTCACGCGGATCAG
CCGCAATCTGCGCGACAGCGACGCGGCGCTCGCGGCGAGCCGCCAGCGCGCGGCGGAGGAGGATCATATCGTGCGCATGG
GGCTGCTCGCCTCGGGCGCGGCGCATGAGCTTGGCACGCCGCTCTCGACCCTGTCGGTGCTGATCGGCGACTGGAAAGCC
GCGGCGCGGCTGGAGGACGACCGCGAATTGCAGGAGGATCTGGCCGATATGGACGCGGCGGTGCAGCGATGCAAGGCGAT
CGTCAGCGGCATTTTGATGTCAGCGGGCGAGGCGCGCGGCGAGGCGCCGCAACTTACCACGATGCGCGCGGCGTTCGGCG
AGATCGTTGCCCACGCGCGCGCGGCGCGCCGCCCCGACACGCTGGAGTTTCACGACCGCTTTGGCGCCGATGTCGCCATC
GTCTCCGACCCCGCGTTGCGGCAGGTGATCGGCAATGTGCTCGACAATGCCGCCGAAGTGTCGCCGGGCTGGACCAGCTT
CACCGCGTCGCGCGATGGCGAGATGCTGGTGATCGAAATCGCCGACCGCGGCCCCGGTTTCAGCGACGAGATGATCGACG
GGTTCGGCCAGCCCTATCGCTCGACCAAGGGGCGCCCCGGCGGCGGGCTGGGGTTGTTCCTGCTCGTCAATGTGCTGCGC
AAGCTGGGCGGCGGGGCCACGGTCGCCAACCGCGACGAAGGCGGGGCGCTCGTGCGGATATGGCTGCCGATCGCGGCGCT
CGCGCGGCTGGGTGGAGGAACGGCATGA

Upstream 100 bases:

>100_bases
TGCGCTTTCGCGACAATCACCTCGTCTACGCACTGACCTGGTTCGCGCTCAGCGCACTCAGTCTCTTTTTTGCGTGGCGA
CTGTGGCATAGTCGCGACTG

Downstream 100 bases:

>100_bases
GCGAGACGCGCCAATTGCTCATTGTCGAGGATGACGAGGCGTTCGCGCGGACGCTGAAACGCTCGTTCGAGCGGCGCGGC
TATGAGGTGTTCGTGGCGGG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MTDLSILPPAPSTAPAGRRNMALLIQLRWLAVGGQLATIGIVSGPMGISLERAPLLGAILVLIAINLASAALLRRGRAVT
NAELTAALLFDVAALGWQLHHSGGLANPFASLFLLQVVIGAILLTPRSSWAIVVAALIALAALRIDPTPLVLPPAYAADP
MGLYLKGSFVCFLLIAVLLVAFVTRISRNLRDSDAALAASRQRAAEEDHIVRMGLLASGAAHELGTPLSTLSVLIGDWKA
AARLEDDRELQEDLADMDAAVQRCKAIVSGILMSAGEARGEAPQLTTMRAAFGEIVAHARAARRPDTLEFHDRFGADVAI
VSDPALRQVIGNVLDNAAEVSPGWTSFTASRDGEMLVIEIADRGPGFSDEMIDGFGQPYRSTKGRPGGGLGLFLLVNVLR
KLGGGATVANRDEGGALVRIWLPIAALARLGGGTA

Sequences:

>Translated_435_residues
MTDLSILPPAPSTAPAGRRNMALLIQLRWLAVGGQLATIGIVSGPMGISLERAPLLGAILVLIAINLASAALLRRGRAVT
NAELTAALLFDVAALGWQLHHSGGLANPFASLFLLQVVIGAILLTPRSSWAIVVAALIALAALRIDPTPLVLPPAYAADP
MGLYLKGSFVCFLLIAVLLVAFVTRISRNLRDSDAALAASRQRAAEEDHIVRMGLLASGAAHELGTPLSTLSVLIGDWKA
AARLEDDRELQEDLADMDAAVQRCKAIVSGILMSAGEARGEAPQLTTMRAAFGEIVAHARAARRPDTLEFHDRFGADVAI
VSDPALRQVIGNVLDNAAEVSPGWTSFTASRDGEMLVIEIADRGPGFSDEMIDGFGQPYRSTKGRPGGGLGLFLLVNVLR
KLGGGATVANRDEGGALVRIWLPIAALARLGGGTA
>Mature_434_residues
TDLSILPPAPSTAPAGRRNMALLIQLRWLAVGGQLATIGIVSGPMGISLERAPLLGAILVLIAINLASAALLRRGRAVTN
AELTAALLFDVAALGWQLHHSGGLANPFASLFLLQVVIGAILLTPRSSWAIVVAALIALAALRIDPTPLVLPPAYAADPM
GLYLKGSFVCFLLIAVLLVAFVTRISRNLRDSDAALAASRQRAAEEDHIVRMGLLASGAAHELGTPLSTLSVLIGDWKAA
ARLEDDRELQEDLADMDAAVQRCKAIVSGILMSAGEARGEAPQLTTMRAAFGEIVAHARAARRPDTLEFHDRFGADVAIV
SDPALRQVIGNVLDNAAEVSPGWTSFTASRDGEMLVIEIADRGPGFSDEMIDGFGQPYRSTKGRPGGGLGLFLLVNVLRK
LGGGATVANRDEGGALVRIWLPIAALARLGGGTA

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=270, Percent_Identity=29.2592592592593, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=21.9626168224299, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45544; Mature: 45412

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSILPPAPSTAPAGRRNMALLIQLRWLAVGGQLATIGIVSGPMGISLERAPLLGAIL
CCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHCCCCEEEEEEECCCCCCCCCHHHHHHHHH
VLIAINLASAALLRRGRAVTNAELTAALLFDVAALGWQLHHSGGLANPFASLFLLQVVIG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHH
AILLTPRSSWAIVVAALIALAALRIDPTPLVLPPAYAADPMGLYLKGSFVCFLLIAVLLV
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHH
AFVTRISRNLRDSDAALAASRQRAAEEDHIVRMGLLASGAAHELGTPLSTLSVLIGDWKA
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHEEEHHHHHCCCHHHHCCCHHHHHHHHHCHHH
AARLEDDRELQEDLADMDAAVQRCKAIVSGILMSAGEARGEAPQLTTMRAAFGEIVAHAR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
AARRPDTLEFHDRFGADVAIVSDPALRQVIGNVLDNAAEVSPGWTSFTASRDGEMLVIEI
HHCCCCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEE
ADRGPGFSDEMIDGFGQPYRSTKGRPGGGLGLFLLVNVLRKLGGGATVANRDEGGALVRI
ECCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCEEEH
WLPIAALARLGGGTA
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDLSILPPAPSTAPAGRRNMALLIQLRWLAVGGQLATIGIVSGPMGISLERAPLLGAIL
CCCCCCCCCCCCCCCCCCCEEEEEEEEEHHCCCCEEEEEEECCCCCCCCCHHHHHHHHH
VLIAINLASAALLRRGRAVTNAELTAALLFDVAALGWQLHHSGGLANPFASLFLLQVVIG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHH
AILLTPRSSWAIVVAALIALAALRIDPTPLVLPPAYAADPMGLYLKGSFVCFLLIAVLLV
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHH
AFVTRISRNLRDSDAALAASRQRAAEEDHIVRMGLLASGAAHELGTPLSTLSVLIGDWKA
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHEEEHHHHHCCCHHHHCCCHHHHHHHHHCHHH
AARLEDDRELQEDLADMDAAVQRCKAIVSGILMSAGEARGEAPQLTTMRAAFGEIVAHAR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
AARRPDTLEFHDRFGADVAIVSDPALRQVIGNVLDNAAEVSPGWTSFTASRDGEMLVIEI
HHCCCCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEE
ADRGPGFSDEMIDGFGQPYRSTKGRPGGGLGLFLLVNVLRKLGGGATVANRDEGGALVRI
ECCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCEEEH
WLPIAALARLGGGTA
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]