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The map label for this gene is yisK [H]

Identifier: 103486872

GI number: 103486872

Start: 1441559

End: 1442467

Strand: Reverse

Name: yisK [H]

Synonym: Sala_1386

Alternate gene names: 103486872

Gene position: 1442467-1441559 (Counterclockwise)

Preceding gene: 103486873

Following gene: 103486871

Centisome position: 43.12

GC content: 63.37

Gene sequence:

>909_bases
ATGCGCTTCGTAACATATCGCACGGTCGAAACCGAACCGCGGCTGGGCCTTCTCCACGACGGCCTTGTGATCGATGTCGA
TTATTTCGGCGATGCGATCGGGCAGGATTTGCCATCGACGATGCTCGATTTCATCGACCTGGGACCGATCGGCCCGCGCT
TCCTGCGCGAAGCGGTCGAAAGCGCGACGCCCGCCGACCTGCTCGGCACTTCGCTGCCCCAGGGCAATGTCACCTTGCTC
GCGCCGATCCCGCGCCCGCGCAAGAATATCTTCGGCATCGGGCTTAACTATACCGAGCATGTCGCCGAATCCGCCCGCGC
GCTCGATACCGCGCACGAACTGCCGCAGCAGCCGGTGATCTTCTCGAAGCCGCCCACGGCCGTCGCCGCGTGGAACGACC
CGATCCGTCACAATGCGAAAGTGACACAGCAACTCGACTGGGAAACTGAATTGGCGGTGATCATCGGCAGTACCGCGCGC
GGCGTGGCCGAGGCCGACGCGCTGAACCACGTGTTCGGCTATACCGTCATCAACGATGTGTCGGCGCGTGACTGCCGCCG
CGCCGGGCAATGGATCGTCTCGAAAGGGCAGGACAGCTTTGCCCCCATGGGGCCATGCATCGTCACCGCCGACGAGATCG
GCGACCCGCATAATCTCAATATCCTCACCCATGTGAACGGAGTGGAAAAGCAGAACAGCAACACGCGCTTCATGCTGTTC
AACGTGCCCCAGCTGATCGCTGACATTGCCCGTGTGATGACGCTCGAACCCGGCGACATCATCGCGACCGGAACGCCCGC
CGGGGTCGGCGCGGGGCGCGATCCGCAGGAGTTTCTGTGGCCCGGCGATGTCGTCGAATGCACCGTCGAAGGCATCGGCA
CACTCCGCAACCCGGTTGTCGCGGTCTGA

Upstream 100 bases:

>100_bases
CGGAAGAAGCCTTCCTCTTCTCGTTCAACGACTTCCCCGTGATGGAGGCGCTCGGCGTCCGGATCGAGGAACCTTTCCCG
AAAAACGACGGACATCAAAT

Downstream 100 bases:

>100_bases
CCCTTTTTTGCATCCCGGCAAAGGTCGGGATGACGGTCTCACACTTTATGCAGGATGTTTCGAGGCAATATATGAACAGG
CCCATCCGCATCGGGCAGAT

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRFVTYRTVETEPRLGLLHDGLVIDVDYFGDAIGQDLPSTMLDFIDLGPIGPRFLREAVESATPADLLGTSLPQGNVTLL
APIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVIFSKPPTAVAAWNDPIRHNAKVTQQLDWETELAVIIGSTAR
GVAEADALNHVFGYTVINDVSARDCRRAGQWIVSKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLF
NVPQLIADIARVMTLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIGTLRNPVVAV

Sequences:

>Translated_302_residues
MRFVTYRTVETEPRLGLLHDGLVIDVDYFGDAIGQDLPSTMLDFIDLGPIGPRFLREAVESATPADLLGTSLPQGNVTLL
APIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVIFSKPPTAVAAWNDPIRHNAKVTQQLDWETELAVIIGSTAR
GVAEADALNHVFGYTVINDVSARDCRRAGQWIVSKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLF
NVPQLIADIARVMTLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIGTLRNPVVAV
>Mature_302_residues
MRFVTYRTVETEPRLGLLHDGLVIDVDYFGDAIGQDLPSTMLDFIDLGPIGPRFLREAVESATPADLLGTSLPQGNVTLL
APIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVIFSKPPTAVAAWNDPIRHNAKVTQQLDWETELAVIIGSTAR
GVAEADALNHVFGYTVINDVSARDCRRAGQWIVSKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLF
NVPQLIADIARVMTLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIGTLRNPVVAV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=306, Percent_Identity=39.8692810457516, Blast_Score=200, Evalue=1e-51,
Organism=Homo sapiens, GI40786394, Length=306, Percent_Identity=39.8692810457516, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=38.265306122449, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=38.265306122449, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI13654274, Length=196, Percent_Identity=38.265306122449, Blast_Score=128, Evalue=7e-30,
Organism=Escherichia coli, GI1787428, Length=216, Percent_Identity=32.8703703703704, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17557057, Length=203, Percent_Identity=32.512315270936, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6324161, Length=240, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28572127, Length=305, Percent_Identity=40, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24663695, Length=304, Percent_Identity=34.8684210526316, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI28571789, Length=214, Percent_Identity=35.0467289719626, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 32642; Mature: 32642

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVTYRTVETEPRLGLLHDGLVIDVDYFGDAIGQDLPSTMLDFIDLGPIGPRFLREAVE
CCEEEEEEECCCCCCEEEECCEEEEEHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
SATPADLLGTSLPQGNVTLLAPIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVI
CCCCHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEE
FSKPPTAVAAWNDPIRHNAKVTQQLDWETELAVIIGSTARGVAEADALNHVFGYTVINDV
ECCCCCEEEECCCCHHCCCHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC
SARDCRRAGQWIVSKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLF
CHHHHHHHCCCEEECCCCCCCCCCCEEEEHHHCCCCCCCEEEEECCCCCCCCCCCEEEEE
NVPQLIADIARVMTLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIGTLRNPVV
ECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCCCHHEEEEHHHHHHHCCCEE
AV
CC
>Mature Secondary Structure
MRFVTYRTVETEPRLGLLHDGLVIDVDYFGDAIGQDLPSTMLDFIDLGPIGPRFLREAVE
CCEEEEEEECCCCCCEEEECCEEEEEHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
SATPADLLGTSLPQGNVTLLAPIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVI
CCCCHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEE
FSKPPTAVAAWNDPIRHNAKVTQQLDWETELAVIIGSTARGVAEADALNHVFGYTVINDV
ECCCCCEEEECCCCHHCCCHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC
SARDCRRAGQWIVSKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLF
CHHHHHHHCCCEEECCCCCCCCCCCEEEEHHHCCCCCCCEEEEECCCCCCCCCCCEEEEE
NVPQLIADIARVMTLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIGTLRNPVV
ECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCCCHHEEEEHHHHHHHCCCEE
AV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]