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The map label for this gene is ntrY [H]

Identifier: 103486760

GI number: 103486760

Start: 1330045

End: 1332366

Strand: Reverse

Name: ntrY [H]

Synonym: Sala_1274

Alternate gene names: 103486760

Gene position: 1332366-1330045 (Counterclockwise)

Preceding gene: 103486761

Following gene: 103486759

Centisome position: 39.83

GC content: 63.57

Gene sequence:

>2322_bases
ATGCAACAGGAATGTCGTAATGAAGCAACAATGACGCCTGTGGCTGCCCCGACCTTCGACATGGATTCGGACAGATCGAA
CGCGCGTGCGGGTTTCTGGCGCTTCGGCGTTCCCGAATATTATGCGCTCGCGGCCATGGTCAGCATCGCGATCGCCACCT
ATATTTTCGTGACCGGCGACGCGCAGAGCGAGCGGCTTCTCACGCCCGCACTGGTGGCCGCGATCATGGTCGCCAATCTG
GTTCCGGCGATGGCGTTGATCGTACTGATCGGCAGCCGCGTGGCGCGCACGCGCGCTGTGCGGTCGATGGCGGGAGGCAA
CGGGCGCCTGCACGTTCGCCTCGTCGCCCTCTTTTCGCTGATTGCGGCAACGCCGACATTGCTCGTCGTGATTTTCGCTT
CGCTGCTCTTCCAGTTCGGTGTCGATTTCTGGTTTTCGGACCGCTCGCGCGGGATGTTCGAGAATGCGGCGAACCTGGCC
GAGGGTTATTATCAGGAAAATCAGCGTCAGGTCGGCGCAAACACCTTTGCGATGGCGACCGATCTCGGCATGCGGCTGCG
GCAATATCCGATCGATGCACCGGGATTTAACGACTATTATTTTCAACAGGTTGTCGTCCGTAGTTTGAATGAATCGGCGA
TTATCGAGATCGGACGCGATGGCGTTGCGCGGACGGCGACGGCGATCGACCCAGACGAACGGCCCGCGACGAGCCGCCTC
ACTCCGCAAATGATCGCGCGTCTCGACGCGGGCGAAGATGTCGTTGTCGTGCGCCGTTCGGACCGTATTGAGGCTGCGGC
CCGCTTGCCGGGCACCGACCGCGCCTTTGTTTATGCGTCGCGCGACACCAATGTACCGGGTTTTCAGCAATCGGCGCGGG
CCAGCGCGGTGCTGGCCGATTACAATCAGCTCTTTGATCGCTCGCAGATGCTTCAGTTGCAGTTCAACGGCGCGCTTTAC
CTCGGCTCGCTGCTCCTGCTCGCGCTGGCCGTGATCGCTGCGATCGTGGTCGCCGACCGCATCGTCCGGCCGCTCGGCAC
GCTGATCGGCGCGACGCGGACCGCGGCGGGCGGCGACCTGTCGGTTCGCGTAACGCCCCCCGAGCGCGACGACGAGATTT
CGGTGCTGACGCGCGCATTCAACCGGATGACCGAGCAGCTCGAGCGGCAAACGCGTGCGCTCGTCAATGCGAACGAGCAG
CTCGAGGCGCGGCGCAGCTTTATCGAGGCGGTGCTGAGCGGCGTGTCTTCGGCGGTGGTATCGGTCGATGCCGACCGCCG
CATCCTGCTCGCCAATGCCGCGGCGGAAAGGCTCATCGGTCGCTCGGCCGACGAGCTGACGGGACTTCTGCTGGACGAGG
TCGCGCCCGAGCTGGCGCAATTGCTGACCGGGAACGAGCGCGAGGCGATCGTCCAGCTTGTGCGCAAGGACAGCGAACCG
GCGACACTCGCGGCGAAGGCGGTGGCGCAGGGTGACGGCTTCGTCCTCAGTTTTGAAGACATAACGCAGCAATTGCTCGA
TCAGCGTCGCGCCGCCTGGTCGGACGTTGCGCGCCGGATCGCGCACGAGATCAAGAATCCGCTTACCCCGATCCAGCTTG
CCGCCGAGCGGTTGCAGCGCCGTTTCGGCGACCGTGTCGAGGGCGATGCGCCGACGTTCCGCAAGCTGACCGACACGGTG
ATCCGCCAGGTTCACGACATGCGCCGCATGGTCGACGAGTTTTCCAGCTTTGCGCGAATGCCCAAGCCGACCTTCGGCGT
CGAGGATGTACGAGACATCTTGCGGCAGGCGGTGTTCCTGTTCGAGGTTGCCAAGCCCGACATCGCCTTCACGGTCAGGA
CGCCTGCCGAGGTCGAACCGCTGGTGTGCGACCGTCGCCTGCTGTCGCAAGCCATAACGAACATCGTCAAGAACGCTGTC
GAAGCAATTGAAGAAAAATATAAAAACTCTGACGCAACGGCTGTTGGCTCGATCCGGGCGGAACTGGAGATTGGCGCGCA
CGATGCGATCGTGATCCGCGTCACCGACGACGGTATCGGGCTACCCGAAGCGCGCGACGCGATCGCCGAACCCTATATGA
CGACGCGGCAGGGCGGGACGGGCCTCGGCCTCGCCATCGTCAAAAAGATCGTCGAGCAACATTATGGCGAACTGGAGTTC
GCCGACAATCCGGCGGGGCAGGGGACGTGCGTAACCCTGACGCTGCACCCCGAACGGCTGCGGCCGCTGGCCGGGCAGGG
CGACGACAATGGTCCGGGCAAGAGCGAGACGGTTCCGGGACGCATCCGCAACCGGAAGGACAGGGAAGACCATGGCGCTT
GA

Upstream 100 bases:

>100_bases
TGCGCAAGCGCCTCGCTCAGCTGGAAATCGATCCGCTGCATCCCTGAAGCGCAGCCTGTTCGCGGCGAACGGGCATGGCG
GGCGCGATTGTGTGTTTTCT

Downstream 100 bases:

>100_bases
TATTCTGATCGTCGATGATGAACGCGACATATGCGAGCTCGTCGCTGGGGTCATGGAAGACGAAGGCTATGAAGCGCGGA
CCGCGTCGGACAGCGATTCG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MQQECRNEATMTPVAAPTFDMDSDRSNARAGFWRFGVPEYYALAAMVSIAIATYIFVTGDAQSERLLTPALVAAIMVANL
VPAMALIVLIGSRVARTRAVRSMAGGNGRLHVRLVALFSLIAATPTLLVVIFASLLFQFGVDFWFSDRSRGMFENAANLA
EGYYQENQRQVGANTFAMATDLGMRLRQYPIDAPGFNDYYFQQVVVRSLNESAIIEIGRDGVARTATAIDPDERPATSRL
TPQMIARLDAGEDVVVVRRSDRIEAAARLPGTDRAFVYASRDTNVPGFQQSARASAVLADYNQLFDRSQMLQLQFNGALY
LGSLLLLALAVIAAIVVADRIVRPLGTLIGATRTAAGGDLSVRVTPPERDDEISVLTRAFNRMTEQLERQTRALVNANEQ
LEARRSFIEAVLSGVSSAVVSVDADRRILLANAAAERLIGRSADELTGLLLDEVAPELAQLLTGNEREAIVQLVRKDSEP
ATLAAKAVAQGDGFVLSFEDITQQLLDQRRAAWSDVARRIAHEIKNPLTPIQLAAERLQRRFGDRVEGDAPTFRKLTDTV
IRQVHDMRRMVDEFSSFARMPKPTFGVEDVRDILRQAVFLFEVAKPDIAFTVRTPAEVEPLVCDRRLLSQAITNIVKNAV
EAIEEKYKNSDATAVGSIRAELEIGAHDAIVIRVTDDGIGLPEARDAIAEPYMTTRQGGTGLGLAIVKKIVEQHYGELEF
ADNPAGQGTCVTLTLHPERLRPLAGQGDDNGPGKSETVPGRIRNRKDREDHGA

Sequences:

>Translated_773_residues
MQQECRNEATMTPVAAPTFDMDSDRSNARAGFWRFGVPEYYALAAMVSIAIATYIFVTGDAQSERLLTPALVAAIMVANL
VPAMALIVLIGSRVARTRAVRSMAGGNGRLHVRLVALFSLIAATPTLLVVIFASLLFQFGVDFWFSDRSRGMFENAANLA
EGYYQENQRQVGANTFAMATDLGMRLRQYPIDAPGFNDYYFQQVVVRSLNESAIIEIGRDGVARTATAIDPDERPATSRL
TPQMIARLDAGEDVVVVRRSDRIEAAARLPGTDRAFVYASRDTNVPGFQQSARASAVLADYNQLFDRSQMLQLQFNGALY
LGSLLLLALAVIAAIVVADRIVRPLGTLIGATRTAAGGDLSVRVTPPERDDEISVLTRAFNRMTEQLERQTRALVNANEQ
LEARRSFIEAVLSGVSSAVVSVDADRRILLANAAAERLIGRSADELTGLLLDEVAPELAQLLTGNEREAIVQLVRKDSEP
ATLAAKAVAQGDGFVLSFEDITQQLLDQRRAAWSDVARRIAHEIKNPLTPIQLAAERLQRRFGDRVEGDAPTFRKLTDTV
IRQVHDMRRMVDEFSSFARMPKPTFGVEDVRDILRQAVFLFEVAKPDIAFTVRTPAEVEPLVCDRRLLSQAITNIVKNAV
EAIEEKYKNSDATAVGSIRAELEIGAHDAIVIRVTDDGIGLPEARDAIAEPYMTTRQGGTGLGLAIVKKIVEQHYGELEF
ADNPAGQGTCVTLTLHPERLRPLAGQGDDNGPGKSETVPGRIRNRKDREDHGA
>Mature_773_residues
MQQECRNEATMTPVAAPTFDMDSDRSNARAGFWRFGVPEYYALAAMVSIAIATYIFVTGDAQSERLLTPALVAAIMVANL
VPAMALIVLIGSRVARTRAVRSMAGGNGRLHVRLVALFSLIAATPTLLVVIFASLLFQFGVDFWFSDRSRGMFENAANLA
EGYYQENQRQVGANTFAMATDLGMRLRQYPIDAPGFNDYYFQQVVVRSLNESAIIEIGRDGVARTATAIDPDERPATSRL
TPQMIARLDAGEDVVVVRRSDRIEAAARLPGTDRAFVYASRDTNVPGFQQSARASAVLADYNQLFDRSQMLQLQFNGALY
LGSLLLLALAVIAAIVVADRIVRPLGTLIGATRTAAGGDLSVRVTPPERDDEISVLTRAFNRMTEQLERQTRALVNANEQ
LEARRSFIEAVLSGVSSAVVSVDADRRILLANAAAERLIGRSADELTGLLLDEVAPELAQLLTGNEREAIVQLVRKDSEP
ATLAAKAVAQGDGFVLSFEDITQQLLDQRRAAWSDVARRIAHEIKNPLTPIQLAAERLQRRFGDRVEGDAPTFRKLTDTV
IRQVHDMRRMVDEFSSFARMPKPTFGVEDVRDILRQAVFLFEVAKPDIAFTVRTPAEVEPLVCDRRLLSQAITNIVKNAV
EAIEEKYKNSDATAVGSIRAELEIGAHDAIVIRVTDDGIGLPEARDAIAEPYMTTRQGGTGLGLAIVKKIVEQHYGELEF
ADNPAGQGTCVTLTLHPERLRPLAGQGDDNGPGKSETVPGRIRNRKDREDHGA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=381, Percent_Identity=24.9343832020997, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1790300, Length=353, Percent_Identity=26.9121813031161, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=29.4372294372294, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=31.0810810810811, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84626; Mature: 84626

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQECRNEATMTPVAAPTFDMDSDRSNARAGFWRFGVPEYYALAAMVSIAIATYIFVTGD
CCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHEEECC
AQSERLLTPALVAAIMVANLVPAMALIVLIGSRVARTRAVRSMAGGNGRLHVRLVALFSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
IAATPTLLVVIFASLLFQFGVDFWFSDRSRGMFENAANLAEGYYQENQRQVGANTFAMAT
HHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
DLGMRLRQYPIDAPGFNDYYFQQVVVRSLNESAIIEIGRDGVARTATAIDPDERPATSRL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHCCCCCCCCCCCCCCCC
TPQMIARLDAGEDVVVVRRSDRIEAAARLPGTDRAFVYASRDTNVPGFQQSARASAVLAD
CHHHHHHCCCCCCEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
YNQLFDRSQMLQLQFNGALYLGSLLLLALAVIAAIVVADRIVRPLGTLIGATRTAAGGDL
HHHHHCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
SVRVTPPERDDEISVLTRAFNRMTEQLERQTRALVNANEQLEARRSFIEAVLSGVSSAVV
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHE
SVDADRRILLANAAAERLIGRSADELTGLLLDEVAPELAQLLTGNEREAIVQLVRKDSEP
EECCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
ATLAAKAVAQGDGFVLSFEDITQQLLDQRRAAWSDVARRIAHEIKNPLTPIQLAAERLQR
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RFGDRVEGDAPTFRKLTDTVIRQVHDMRRMVDEFSSFARMPKPTFGVEDVRDILRQAVFL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
FEVAKPDIAFTVRTPAEVEPLVCDRRLLSQAITNIVKNAVEAIEEKYKNSDATAVGSIRA
HHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEE
ELEIGAHDAIVIRVTDDGIGLPEARDAIAEPYMTTRQGGTGLGLAIVKKIVEQHYGELEF
EEEECCCCEEEEEECCCCCCCCHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHCCCEEE
ADNPAGQGTCVTLTLHPERLRPLAGQGDDNGPGKSETVPGRIRNRKDREDHGA
CCCCCCCCEEEEEEECHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MQQECRNEATMTPVAAPTFDMDSDRSNARAGFWRFGVPEYYALAAMVSIAIATYIFVTGD
CCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHEEECC
AQSERLLTPALVAAIMVANLVPAMALIVLIGSRVARTRAVRSMAGGNGRLHVRLVALFSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
IAATPTLLVVIFASLLFQFGVDFWFSDRSRGMFENAANLAEGYYQENQRQVGANTFAMAT
HHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
DLGMRLRQYPIDAPGFNDYYFQQVVVRSLNESAIIEIGRDGVARTATAIDPDERPATSRL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHCCCCCCCCCCCCCCCC
TPQMIARLDAGEDVVVVRRSDRIEAAARLPGTDRAFVYASRDTNVPGFQQSARASAVLAD
CHHHHHHCCCCCCEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
YNQLFDRSQMLQLQFNGALYLGSLLLLALAVIAAIVVADRIVRPLGTLIGATRTAAGGDL
HHHHHCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
SVRVTPPERDDEISVLTRAFNRMTEQLERQTRALVNANEQLEARRSFIEAVLSGVSSAVV
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHE
SVDADRRILLANAAAERLIGRSADELTGLLLDEVAPELAQLLTGNEREAIVQLVRKDSEP
EECCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
ATLAAKAVAQGDGFVLSFEDITQQLLDQRRAAWSDVARRIAHEIKNPLTPIQLAAERLQR
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RFGDRVEGDAPTFRKLTDTVIRQVHDMRRMVDEFSSFARMPKPTFGVEDVRDILRQAVFL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
FEVAKPDIAFTVRTPAEVEPLVCDRRLLSQAITNIVKNAVEAIEEKYKNSDATAVGSIRA
HHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEE
ELEIGAHDAIVIRVTDDGIGLPEARDAIAEPYMTTRQGGTGLGLAIVKKIVEQHYGELEF
EEEECCCCEEEEEECCCCCCCCHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHCCCEEE
ADNPAGQGTCVTLTLHPERLRPLAGQGDDNGPGKSETVPGRIRNRKDREDHGA
CCCCCCCCEEEEEEECHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]