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The map label for this gene is pleC [H]

Identifier: 103486656

GI number: 103486656

Start: 1202163

End: 1203533

Strand: Direct

Name: pleC [H]

Synonym: Sala_1168

Alternate gene names: 103486656

Gene position: 1202163-1203533 (Clockwise)

Preceding gene: 103486655

Following gene: 103486661

Centisome position: 35.94

GC content: 70.39

Gene sequence:

>1371_bases
ATGAGCGAGCGCGTCGTCCGCGGCCGCGTTGACCGGTCGGGCGTACTGGTGAGCGCCGATGTGCCGCTGTTGCGGCTTCA
GCAACGCGCGGGGGCGGGGCTTGGCAGGCCGCTCGCGCTGCCGCACCTCGCGCGGCTCGTCGCACTGTCGCAGCGGCTGC
ACCGCGAGATCAGTCGTCCGCTCCACGCCGCCGACGACCATAGCGACATCCACGCGCTCGTGCGCATCACGCCCGACGAC
GAGGGCGCGAGCCTCGAAATCAGCGACTGGCGCGCGCGCGCTGTGACGCCGCCCGGCATACCGCCCGTCACCGACGAGAC
CCCGATGGCCGACGGATGGGCGTGGGAGTGTGACCAGCAGCTACGGCTCGTGGCGCTCCGCGCTGCGGGGAAGGCGCCTG
CGGTGCCGCCTGGATGGGAAGGGCGCTCGCTGTCTGAATTGTTCGAGTTGCAGCCCGACGCCGATGGCCGCTTTCCGGTG
TTGCGCGCGCTCGCGCGGCAGTCGCGCTTTGAAGGGCAGCGCGTGCAGGCTGCGGGCGCGGCGATGACGCTTGGCGGTGA
CGCGCTGTTCGATGCGGCGGGTCGCTTCACGGGCTTTCGCGGCTTCGCCTCGATTGTCGACGGGCCGCCCGCCACGGCGC
CGAAGGGCGGCGGGGCACCGGTCGATCCTGCCTTTGGTTCGCTGCCGCTGTCCGACCCGCAGTTCGGCCGCCGCATCGAC
GGCGCGCTGCGCGGCCCACTCAGCCGCATCATCGCGACCGCGGAGACGATTTCGGGGCAGTTCGACGGGCCGATCCGCGC
CGATTACGCGCGCTATGCCGGCGACATTGCCCATGCCGGGCGGCATCTGCTGGGCCTTGTCGACGACCTTGCCGACCTTC
AGAATATCGAACGGCCGGGGTTCAAGGCGGCGCGCGACGACATCGACCTCGGCGACCTGGCGCGCCGCGCGGTCGGTCTG
CTCGGCATGAAGGCCGAGGAGAAGGGGATTCGCATTTCGGCGCCCAGCACCGACGACCGGATGCCCGCAACGGGCGAGTT
TCGCCGCGTGTTGCAGGTGCTGCTCAACCTGCTGGGCAATGCGATCCGCTATTCGCCCGAGGATTCGCAGATATGGATCC
GCGTCGATCGCGAGGGCGACCGTGCGATGGTCACCGTCGCCGATCAGGGGCAGGGAATCGACGCGGAGCAGCAGGCGATG
GTGTTCGAAAAGTTCGAGCGGCTCGGACGCACCGACAGCGGCGGATCGGGCCTCGGACTCTATATCGCCCGCCGCCTTGC
GCGCGCGATGGACGGCGACCTGACCGTCGACAGCGCACCGGGTCAGGGCGCGCGTTTCACGTTGAGCCTGCCGGCGCGGG
ATGAGGAGTAA

Upstream 100 bases:

>100_bases
TCGACCGTGAAGCGCTGGCCCCGCTCGAAGCGTCGCTGGCAATGCTCACCGCGCGCGCGGTGAGCGACGCCGATGGCGTC
ACGGCGGCGGAGACGGGGCG

Downstream 100 bases:

>100_bases
GGAGCAGGCGTTGGGCGGAGATCAGGTCGCCCGGCTATTTCGTCATGCTGAACTCGTTTCAGCATCCATGACCGGACCTC
TGGTCGGTTGCGGCGTCGAA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSERVVRGRVDRSGVLVSADVPLLRLQQRAGAGLGRPLALPHLARLVALSQRLHREISRPLHAADDHSDIHALVRITPDD
EGASLEISDWRARAVTPPGIPPVTDETPMADGWAWECDQQLRLVALRAAGKAPAVPPGWEGRSLSELFELQPDADGRFPV
LRALARQSRFEGQRVQAAGAAMTLGGDALFDAAGRFTGFRGFASIVDGPPATAPKGGGAPVDPAFGSLPLSDPQFGRRID
GALRGPLSRIIATAETISGQFDGPIRADYARYAGDIAHAGRHLLGLVDDLADLQNIERPGFKAARDDIDLGDLARRAVGL
LGMKAEEKGIRISAPSTDDRMPATGEFRRVLQVLLNLLGNAIRYSPEDSQIWIRVDREGDRAMVTVADQGQGIDAEQQAM
VFEKFERLGRTDSGGSGLGLYIARRLARAMDGDLTVDSAPGQGARFTLSLPARDEE

Sequences:

>Translated_456_residues
MSERVVRGRVDRSGVLVSADVPLLRLQQRAGAGLGRPLALPHLARLVALSQRLHREISRPLHAADDHSDIHALVRITPDD
EGASLEISDWRARAVTPPGIPPVTDETPMADGWAWECDQQLRLVALRAAGKAPAVPPGWEGRSLSELFELQPDADGRFPV
LRALARQSRFEGQRVQAAGAAMTLGGDALFDAAGRFTGFRGFASIVDGPPATAPKGGGAPVDPAFGSLPLSDPQFGRRID
GALRGPLSRIIATAETISGQFDGPIRADYARYAGDIAHAGRHLLGLVDDLADLQNIERPGFKAARDDIDLGDLARRAVGL
LGMKAEEKGIRISAPSTDDRMPATGEFRRVLQVLLNLLGNAIRYSPEDSQIWIRVDREGDRAMVTVADQGQGIDAEQQAM
VFEKFERLGRTDSGGSGLGLYIARRLARAMDGDLTVDSAPGQGARFTLSLPARDEE
>Mature_455_residues
SERVVRGRVDRSGVLVSADVPLLRLQQRAGAGLGRPLALPHLARLVALSQRLHREISRPLHAADDHSDIHALVRITPDDE
GASLEISDWRARAVTPPGIPPVTDETPMADGWAWECDQQLRLVALRAAGKAPAVPPGWEGRSLSELFELQPDADGRFPVL
RALARQSRFEGQRVQAAGAAMTLGGDALFDAAGRFTGFRGFASIVDGPPATAPKGGGAPVDPAFGSLPLSDPQFGRRIDG
ALRGPLSRIIATAETISGQFDGPIRADYARYAGDIAHAGRHLLGLVDDLADLQNIERPGFKAARDDIDLGDLARRAVGLL
GMKAEEKGIRISAPSTDDRMPATGEFRRVLQVLLNLLGNAIRYSPEDSQIWIRVDREGDRAMVTVADQGQGIDAEQQAMV
FEKFERLGRTDSGGSGLGLYIARRLARAMDGDLTVDSAPGQGARFTLSLPARDEE

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=30.2631578947368, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87081816, Length=215, Percent_Identity=33.953488372093, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=227, Percent_Identity=28.1938325991189, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=29.3333333333333, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=28, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=214, Percent_Identity=30.3738317757009, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=26.431718061674, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789149, Length=227, Percent_Identity=27.7533039647577, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=210, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788393, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787894, Length=170, Percent_Identity=31.1764705882353, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=25.2252252252252, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48945; Mature: 48814

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERVVRGRVDRSGVLVSADVPLLRLQQRAGAGLGRPLALPHLARLVALSQRLHREISRP
CCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
LHAADDHSDIHALVRITPDDEGASLEISDWRARAVTPPGIPPVTDETPMADGWAWECDQQ
CCCCCCCCCEEEEEEECCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHH
LRLVALRAAGKAPAVPPGWEGRSLSELFELQPDADGRFPVLRALARQSRFEGQRVQAAGA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCC
AMTLGGDALFDAAGRFTGFRGFASIVDGPPATAPKGGGAPVDPAFGSLPLSDPQFGRRID
EEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
GALRGPLSRIIATAETISGQFDGPIRADYARYAGDIAHAGRHLLGLVDDLADLQNIERPG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FKAARDDIDLGDLARRAVGLLGMKAEEKGIRISAPSTDDRMPATGEFRRVLQVLLNLLGN
CCHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
AIRYSPEDSQIWIRVDREGDRAMVTVADQGQGIDAEQQAMVFEKFERLGRTDSGGSGLGL
HHCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHH
YIARRLARAMDGDLTVDSAPGQGARFTLSLPARDEE
HHHHHHHHHHCCCEEEECCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SERVVRGRVDRSGVLVSADVPLLRLQQRAGAGLGRPLALPHLARLVALSQRLHREISRP
CCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
LHAADDHSDIHALVRITPDDEGASLEISDWRARAVTPPGIPPVTDETPMADGWAWECDQQ
CCCCCCCCCEEEEEEECCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHH
LRLVALRAAGKAPAVPPGWEGRSLSELFELQPDADGRFPVLRALARQSRFEGQRVQAAGA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCC
AMTLGGDALFDAAGRFTGFRGFASIVDGPPATAPKGGGAPVDPAFGSLPLSDPQFGRRID
EEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
GALRGPLSRIIATAETISGQFDGPIRADYARYAGDIAHAGRHLLGLVDDLADLQNIERPG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FKAARDDIDLGDLARRAVGLLGMKAEEKGIRISAPSTDDRMPATGEFRRVLQVLLNLLGN
CCHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
AIRYSPEDSQIWIRVDREGDRAMVTVADQGQGIDAEQQAMVFEKFERLGRTDSGGSGLGL
HHCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHH
YIARRLARAMDGDLTVDSAPGQGARFTLSLPARDEE
HHHHHHHHHHCCCEEEECCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]