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The map label for this gene is lplT [H]

Identifier: 103486641

GI number: 103486641

Start: 1188048

End: 1189343

Strand: Reverse

Name: lplT [H]

Synonym: Sala_1153

Alternate gene names: 103486641

Gene position: 1189343-1188048 (Counterclockwise)

Preceding gene: 103486645

Following gene: 103486637

Centisome position: 35.55

GC content: 63.12

Gene sequence:

>1296_bases
ATGACCGGCTCCATTGCGCTGTTGAGGCAACGCCGGTTCCTGCCCCTTTTCGTCACCCAGCTTCTCGGTGCATTCAACGA
CAATCTGTTCAAGAATGCGATGGTGCTGTTCGTCGTTTATGGCGTGTTCAACAGCGAGGAACAGGAAACGCTGTTCAGCG
CGGTCGCCACCGGCGTCTTCATCCTGCCTTTCTTTCTCCTGTCGGCGCTGGCGGGGCAGCTGGCCGACACGCGCGACAAG
GCACGGATCATCCGCATCGTCAAATTCTGCGAAATCCTGATCATGTTCGTCGGCGGCGGCGGGCTGATCCTGGCGTGGCT
CGGTTTTGCGGTGCATCTCATCGCCATCCCGCTGATGATGCTTGCGTTGTTTGCGATGGGAATCCACTCGACCTTTTTCG
GACCGATCAAATATGCGATCCTGCCACAACACCTCAAAAGCGACGAGGTGCTGGCGGGCACCGGGCTGGTCGAGGCGGGG
ACCTATATCGCGATTCTCGCCGGAACGATCCTTGCCGGGGTGATCGAGGTCGAATGGGCGGCGCTCGGCGTCGTGCTGGT
CGCCGCGATCGGTTACTGGACGGGGCGCAAGGTGCCCCCGGCGCCGCCCGAGCATCTGGAAACGGGGATCGACTGGCATA
TCATACGCTCGTCCGTCGCGCTCGTGCGCGGCACGATGCATATCCCGCGCCTCTATCTCGCGATCTTGTCGATCAGCTTT
TTCTGGACGATCGGCGCCGTGCTGTTCATCCAGTTTCCGCCGCTCGCCAAGAATATCCTCCACGCCGACAAAAGTGTCGC
CAGCCTCTTCCTCGCCGTCTTCTCGATCGGGATCGCGATCGGCTCGGTCGCGGTGAACCGGTTGCTGAAGGGCGAGGTGT
CGGCGCGCTACAGCCCGGCGAGCGTGCTCGTCATGGCGCTGTTCGTCGTCGCCTTTTACTGGGTGTGCCGCAACTGGGGT
GTGCAACCCGCGGGGGCGTTGTACGACATCGGCGGCTTCCTTGGACACCCCGGTGTCGTGCCGCTCCTCGCCAGCCTGCT
CGGCATAGCCGTCAGCGGCGGCATGTTTGTCGTTCCGCTCTATGCCTTTCTGACCACCACCGTGCCCAAGGACCAGACCG
CGCGCACTGTCGCCGCGAACAATATCGTCAATTCGGGCGCGATGGTTGCGGGTTCGCTGCTCGCGATGGGGCTCGGCCTC
GCGGGCGTCGGCGTCGTCGACCAGTTGCTGATGAGCGCCGCCATGTGCCTGGTCTCCGCGTGGCTCGCGGTCAAGCTGCA
CCGGGCGTGCGATTAG

Upstream 100 bases:

>100_bases
ACCTTTGACCCCGACCGCCCTAGCCGATAAGCCCCCCCGGCGACAACCTGTTGCCCGCGAAATGCGTGCGAACCGACATA
GTTGAAAAGATTGGACCACC

Downstream 100 bases:

>100_bases
AGCGGCGGGCCCATTTCGGCCCAGCGCAGCGTCGATCGTCGGTCACTATGCGGCAGCATGGCTCCCTCCTCGCCCCTCGC
GCTGGGCCAAATCGGCTCCT

Product: major facilitator transporter

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTGSIALLRQRRFLPLFVTQLLGAFNDNLFKNAMVLFVVYGVFNSEEQETLFSAVATGVFILPFFLLSALAGQLADTRDK
ARIIRIVKFCEILIMFVGGGGLILAWLGFAVHLIAIPLMMLALFAMGIHSTFFGPIKYAILPQHLKSDEVLAGTGLVEAG
TYIAILAGTILAGVIEVEWAALGVVLVAAIGYWTGRKVPPAPPEHLETGIDWHIIRSSVALVRGTMHIPRLYLAILSISF
FWTIGAVLFIQFPPLAKNILHADKSVASLFLAVFSIGIAIGSVAVNRLLKGEVSARYSPASVLVMALFVVAFYWVCRNWG
VQPAGALYDIGGFLGHPGVVPLLASLLGIAVSGGMFVVPLYAFLTTTVPKDQTARTVAANNIVNSGAMVAGSLLAMGLGL
AGVGVVDQLLMSAAMCLVSAWLAVKLHRACD

Sequences:

>Translated_431_residues
MTGSIALLRQRRFLPLFVTQLLGAFNDNLFKNAMVLFVVYGVFNSEEQETLFSAVATGVFILPFFLLSALAGQLADTRDK
ARIIRIVKFCEILIMFVGGGGLILAWLGFAVHLIAIPLMMLALFAMGIHSTFFGPIKYAILPQHLKSDEVLAGTGLVEAG
TYIAILAGTILAGVIEVEWAALGVVLVAAIGYWTGRKVPPAPPEHLETGIDWHIIRSSVALVRGTMHIPRLYLAILSISF
FWTIGAVLFIQFPPLAKNILHADKSVASLFLAVFSIGIAIGSVAVNRLLKGEVSARYSPASVLVMALFVVAFYWVCRNWG
VQPAGALYDIGGFLGHPGVVPLLASLLGIAVSGGMFVVPLYAFLTTTVPKDQTARTVAANNIVNSGAMVAGSLLAMGLGL
AGVGVVDQLLMSAAMCLVSAWLAVKLHRACD
>Mature_430_residues
TGSIALLRQRRFLPLFVTQLLGAFNDNLFKNAMVLFVVYGVFNSEEQETLFSAVATGVFILPFFLLSALAGQLADTRDKA
RIIRIVKFCEILIMFVGGGGLILAWLGFAVHLIAIPLMMLALFAMGIHSTFFGPIKYAILPQHLKSDEVLAGTGLVEAGT
YIAILAGTILAGVIEVEWAALGVVLVAAIGYWTGRKVPPAPPEHLETGIDWHIIRSSVALVRGTMHIPRLYLAILSISFF
WTIGAVLFIQFPPLAKNILHADKSVASLFLAVFSIGIAIGSVAVNRLLKGEVSARYSPASVLVMALFVVAFYWVCRNWGV
QPAGALYDIGGFLGHPGVVPLLASLLGIAVSGGMFVVPLYAFLTTTVPKDQTARTVAANNIVNSGAMVAGSLLAMGLGLA
GVGVVDQLLMSAAMCLVSAWLAVKLHRACD

Specific function: Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family [H]

Homologues:

Organism=Escherichia coli, GI1789200, Length=387, Percent_Identity=25.5813953488372, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: 2.3.1.51

Molecular weight: Translated: 45937; Mature: 45806

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSIALLRQRRFLPLFVTQLLGAFNDNLFKNAMVLFVVYGVFNSEEQETLFSAVATGVF
CCCCHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ILPFFLLSALAGQLADTRDKARIIRIVKFCEILIMFVGGGGLILAWLGFAVHLIAIPLMM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LALFAMGIHSTFFGPIKYAILPQHLKSDEVLAGTGLVEAGTYIAILAGTILAGVIEVEWA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGVVLVAAIGYWTGRKVPPAPPEHLETGIDWHIIRSSVALVRGTMHIPRLYLAILSISF
HHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWTIGAVLFIQFPPLAKNILHADKSVASLFLAVFSIGIAIGSVAVNRLLKGEVSARYSPA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SVLVMALFVVAFYWVCRNWGVQPAGALYDIGGFLGHPGVVPLLASLLGIAVSGGMFVVPL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
YAFLTTTVPKDQTARTVAANNIVNSGAMVAGSLLAMGLGLAGVGVVDQLLMSAAMCLVSA
HHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLAVKLHRACD
HHHHHHHHHCC
>Mature Secondary Structure 
TGSIALLRQRRFLPLFVTQLLGAFNDNLFKNAMVLFVVYGVFNSEEQETLFSAVATGVF
CCCHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ILPFFLLSALAGQLADTRDKARIIRIVKFCEILIMFVGGGGLILAWLGFAVHLIAIPLMM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LALFAMGIHSTFFGPIKYAILPQHLKSDEVLAGTGLVEAGTYIAILAGTILAGVIEVEWA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGVVLVAAIGYWTGRKVPPAPPEHLETGIDWHIIRSSVALVRGTMHIPRLYLAILSISF
HHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWTIGAVLFIQFPPLAKNILHADKSVASLFLAVFSIGIAIGSVAVNRLLKGEVSARYSPA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SVLVMALFVVAFYWVCRNWGVQPAGALYDIGGFLGHPGVVPLLASLLGIAVSGGMFVVPL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
YAFLTTTVPKDQTARTVAANNIVNSGAMVAGSLLAMGLGLAGVGVVDQLLMSAAMCLVSA
HHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLAVKLHRACD
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA