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The map label for this gene is mas [H]

Identifier: 103486348

GI number: 103486348

Start: 866169

End: 867167

Strand: Reverse

Name: mas [H]

Synonym: Sala_0858

Alternate gene names: 103486348

Gene position: 867167-866169 (Counterclockwise)

Preceding gene: 103486349

Following gene: 103486340

Centisome position: 25.92

GC content: 66.17

Gene sequence:

>999_bases
ATGCCCCGCGCCGTTATGGCCAGCGCACTTGGCCCCCCCGACACCTATCGGCTGGTCGAATATGATCCCGGCCCGCCGTC
GCCGAGCCAGGTTCGGATCGCGATCCGCGCCACCGGTATCAGCTATGTCGATGTCTTGACGGCAGCGGGAAATTATCAGG
TCAAACCGCCGCTTCCTTATATCCCCGGCAGCGAATGCGCGGGCATCGTCGAGGCCGTCGGCATGGACGTCGAAGGACTT
TCTGTCGGCGACAAGGTGGTGGGCAGCGGATGGGGCGGCCTGTTCGCCGATGCCGCCAACCTTCCCGCACGAACTGTTCG
GAAAATGCCCGAAACCCTGTCCTTCGAAGAAGCGGCGGTGTTCCCGGTAAGCTATGCAACCGCGCGCCATGCGCTGGTCG
ATCGCGGTCGGCTGGCTGCGGGAGAGACGCTGCTGGTACTGGGAGCGGGCGGCGCCACGGGTTATGCAGCGATCCAGCTT
GGCAAATATCTTGGCGCACAGGTGATCGCGTCGGCGTCGAACGCGACCAAGCGCAGCCTGGCGCGCGCGGGCGGCGCCGA
TGCCGTGATCGACGCGCGCGACCCCGACTGGCGCGCGACGGTAACCGCTGCGACCGGTGGCCAGGGCGTCGATGTCGTGT
TCGACCCCGTCGGAGGCGACGCAACCGACCGGGCATTCCGTTCGCTGGCTTGGAACGGACGGCATCTGGTCATCGGCTTT
CCGGCAGGCATTGCGGCGCTGCGGACCAACTTGCCCTTATTGAAGGGAGCGAGCCTGATCGGAGTGGACGTGCGGCAGTT
CGGCCTGTTCGAACCCGGACGGAGCGAGGCCAACCGTGATGCCATTTTCGACCTGGCGGCGGAAGGCAGGCTGCGCCCGG
CGATCGCGCGAACCTATCCCCTGGAGGATTTTTGCGCCGCAATGCAGGATGCGGAGACCGGCGAAAGCGCGGGACGGATC
GTGCTGACGATGGGTCAGATGTCCAGCACGCCGCGCTAG

Upstream 100 bases:

>100_bases
GCCGCCCCGAGGAAATCGTCACCGCCGCACTGATGCTCGCGAGCCCCTCATCCTCTTATACCACCGGCGCGCTCGTCCGC
GTGGACGGGGGGCAGCGCTG

Downstream 100 bases:

>100_bases
AACGCGATGTCCGCCAACCGCCCCCGCCAATCGGGAAGCGCCGGCAATGCGTTGAAATCACGGCGAAGACGGGCAACGAG
ATCGGCGACCGGTTCGACCA

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPRAVMASALGPPDTYRLVEYDPGPPSPSQVRIAIRATGISYVDVLTAAGNYQVKPPLPYIPGSECAGIVEAVGMDVEGL
SVGDKVVGSGWGGLFADAANLPARTVRKMPETLSFEEAAVFPVSYATARHALVDRGRLAAGETLLVLGAGGATGYAAIQL
GKYLGAQVIASASNATKRSLARAGGADAVIDARDPDWRATVTAATGGQGVDVVFDPVGGDATDRAFRSLAWNGRHLVIGF
PAGIAALRTNLPLLKGASLIGVDVRQFGLFEPGRSEANRDAIFDLAAEGRLRPAIARTYPLEDFCAAMQDAETGESAGRI
VLTMGQMSSTPR

Sequences:

>Translated_332_residues
MPRAVMASALGPPDTYRLVEYDPGPPSPSQVRIAIRATGISYVDVLTAAGNYQVKPPLPYIPGSECAGIVEAVGMDVEGL
SVGDKVVGSGWGGLFADAANLPARTVRKMPETLSFEEAAVFPVSYATARHALVDRGRLAAGETLLVLGAGGATGYAAIQL
GKYLGAQVIASASNATKRSLARAGGADAVIDARDPDWRATVTAATGGQGVDVVFDPVGGDATDRAFRSLAWNGRHLVIGF
PAGIAALRTNLPLLKGASLIGVDVRQFGLFEPGRSEANRDAIFDLAAEGRLRPAIARTYPLEDFCAAMQDAETGESAGRI
VLTMGQMSSTPR
>Mature_331_residues
PRAVMASALGPPDTYRLVEYDPGPPSPSQVRIAIRATGISYVDVLTAAGNYQVKPPLPYIPGSECAGIVEAVGMDVEGLS
VGDKVVGSGWGGLFADAANLPARTVRKMPETLSFEEAAVFPVSYATARHALVDRGRLAAGETLLVLGAGGATGYAAIQLG
KYLGAQVIASASNATKRSLARAGGADAVIDARDPDWRATVTAATGGQGVDVVFDPVGGDATDRAFRSLAWNGRHLVIGFP
AGIAALRTNLPLLKGASLIGVDVRQFGLFEPGRSEANRDAIFDLAAEGRLRPAIARTYPLEDFCAAMQDAETGESAGRIV
LTMGQMSSTPR

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=30.3951367781155, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=30.3951367781155, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=27.5641025641026, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI24308257, Length=360, Percent_Identity=26.3888888888889, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=28.8753799392097, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI22538446, Length=323, Percent_Identity=27.2445820433437, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI22538444, Length=323, Percent_Identity=27.2445820433437, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI41872631, Length=315, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI28557745, Length=306, Percent_Identity=30.3921568627451, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI47519420, Length=331, Percent_Identity=25.9818731117825, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI67078404, Length=306, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=26.0204081632653, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI67078406, Length=298, Percent_Identity=25.1677852348993, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790485, Length=317, Percent_Identity=29.9684542586751, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790045, Length=326, Percent_Identity=24.2331288343558, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=333, Percent_Identity=29.4294294294294, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17536829, Length=209, Percent_Identity=32.5358851674641, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=319, Percent_Identity=28.8401253918495, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324486, Length=343, Percent_Identity=24.7813411078717, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221330659, Length=236, Percent_Identity=28.8135593220339, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920632, Length=236, Percent_Identity=28.8135593220339, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24581345, Length=338, Percent_Identity=24.2603550295858, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550423, Length=304, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 34453; Mature: 34322

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRAVMASALGPPDTYRLVEYDPGPPSPSQVRIAIRATGISYVDVLTAAGNYQVKPPLPY
CCCHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEECCCEEEEHEECCCCEEECCCCCC
IPGSECAGIVEAVGMDVEGLSVGDKVVGSGWGGLFADAANLPARTVRKMPETLSFEEAAV
CCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHCCCCCCHHHHHHCHHHCCCCCCEE
FPVSYATARHALVDRGRLAAGETLLVLGAGGATGYAAIQLGKYLGAQVIASASNATKRSL
EEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
ARAGGADAVIDARDPDWRATVTAATGGQGVDVVFDPVGGDATDRAFRSLAWNGRHLVIGF
HHCCCCCEEEECCCCCCEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEC
PAGIAALRTNLPLLKGASLIGVDVRQFGLFEPGRSEANRDAIFDLAAEGRLRPAIARTYP
CCCHHHHHHCCCHHCCCCEEEECHHHHCCCCCCCCCCCCCCEEEECCCCCCCCHHHHCCC
LEDFCAAMQDAETGESAGRIVLTMGQMSSTPR
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
PRAVMASALGPPDTYRLVEYDPGPPSPSQVRIAIRATGISYVDVLTAAGNYQVKPPLPY
CCHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEECCCEEEEHEECCCCEEECCCCCC
IPGSECAGIVEAVGMDVEGLSVGDKVVGSGWGGLFADAANLPARTVRKMPETLSFEEAAV
CCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHCCCCCCHHHHHHCHHHCCCCCCEE
FPVSYATARHALVDRGRLAAGETLLVLGAGGATGYAAIQLGKYLGAQVIASASNATKRSL
EEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
ARAGGADAVIDARDPDWRATVTAATGGQGVDVVFDPVGGDATDRAFRSLAWNGRHLVIGF
HHCCCCCEEEECCCCCCEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEC
PAGIAALRTNLPLLKGASLIGVDVRQFGLFEPGRSEANRDAIFDLAAEGRLRPAIARTYP
CCCHHHHHHCCCHHCCCCEEEECHHHHCCCCCCCCCCCCCCEEEECCCCCCCCHHHHCCC
LEDFCAAMQDAETGESAGRIVLTMGQMSSTPR
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]