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The map label for this gene is moaC [H]

Identifier: 103486324

GI number: 103486324

Start: 840247

End: 841080

Strand: Reverse

Name: moaC [H]

Synonym: Sala_0834

Alternate gene names: 103486324

Gene position: 841080-840247 (Counterclockwise)

Preceding gene: 103486325

Following gene: 103486323

Centisome position: 25.14

GC content: 66.19

Gene sequence:

>834_bases
TTGGAGTGGGGCGCGGCCATGAAGCCCTCTCCCCTTCAGGGGAGAGGGTTGGGAGAGGGGGACCATCCAAACCCCTCTCA
ACTCCGGCTAGCCAGCAAGCTGGCAAGCCTGCGTATCTCTCCCCTGAAGGGGAGAGAGCCACTATGTCCGCTTCCGGCCG
GTTTCAGACCTTCCCCACTTTCCGTTCGTGTCGAGCGAAGTCGAGACACCCATCGACACCAGGCCATGTCGAGGGGCATC
TCGACTTCGCTCGATGCGAACGGATTTTATATGCTGTCATGTCCGCAACCGGCCGTTCCCCGACAATTCCTCCTCCTGTC
CCCCCTTGCCTTTCGCTCGCCGCCTTGCTTCGCTGGCGCGATGACGCTCAAACCGACTCATCTCGACGACAGCGGCGCCG
CACATATGGTCGATGTCGGCGCCAAGCCCGCGACCCAGCGCCGCGCCGTCGCCGCCGGGCGCATCACGATGACCGCGGCG
GCGCTCGACGCGATCCGCAGCGGCAACGCGCCCAAGGGCGACGTGCTGTCGACCGCGCGCATCGCGGGGATCATGGCGGC
AAAGCGCACCGCCGACCTTATTCCGCTTTGCCACCCGCTCGCGCTCACCAGCGTGACCGTCGATTTCGCGTGGCAGACCG
ATGGTATCGCCGTGACCGCGACCGCCGCGACCAGCGGGCCGACCGGCGTGGAGATGGAGGCGTTCACCGCCGCATCGGTC
GCGCTGCTCACCCTTTACGACATGGCGAAGGCGCTCGACCGTACAATGGTGATCGGCGACATCCGCCTGCTCGAAAAAAG
CGGCGGCCGTTCGGGCGACTGGCGCGCCGCATGA

Upstream 100 bases:

>100_bases
CCGACAGCGGCGTCCGGGCCTTCCTCGTCGGCGAAAGCCTGATGCGTCAGGCCGACGTCACGGCGGTAACAAGGGCGCTG
CTCGAAGGCTGAGGCCCGCT

Downstream 100 bases:

>100_bases
GCGCACTGCTCCCCGTCGAGGAGGCGCAGGCGCGCCTGCTCGCGCTGCGCGCGCCGCTGGGACGCGAGACGGTCGCGCTC
GCCGACGCGCATGGCCGCTA

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MEWGAAMKPSPLQGRGLGEGDHPNPSQLRLASKLASLRISPLKGREPLCPLPAGFRPSPLSVRVERSRDTHRHQAMSRGI
STSLDANGFYMLSCPQPAVPRQFLLLSPLAFRSPPCFAGAMTLKPTHLDDSGAAHMVDVGAKPATQRRAVAAGRITMTAA
ALDAIRSGNAPKGDVLSTARIAGIMAAKRTADLIPLCHPLALTSVTVDFAWQTDGIAVTATAATSGPTGVEMEAFTAASV
ALLTLYDMAKALDRTMVIGDIRLLEKSGGRSGDWRAA

Sequences:

>Translated_277_residues
MEWGAAMKPSPLQGRGLGEGDHPNPSQLRLASKLASLRISPLKGREPLCPLPAGFRPSPLSVRVERSRDTHRHQAMSRGI
STSLDANGFYMLSCPQPAVPRQFLLLSPLAFRSPPCFAGAMTLKPTHLDDSGAAHMVDVGAKPATQRRAVAAGRITMTAA
ALDAIRSGNAPKGDVLSTARIAGIMAAKRTADLIPLCHPLALTSVTVDFAWQTDGIAVTATAATSGPTGVEMEAFTAASV
ALLTLYDMAKALDRTMVIGDIRLLEKSGGRSGDWRAA
>Mature_277_residues
MEWGAAMKPSPLQGRGLGEGDHPNPSQLRLASKLASLRISPLKGREPLCPLPAGFRPSPLSVRVERSRDTHRHQAMSRGI
STSLDANGFYMLSCPQPAVPRQFLLLSPLAFRSPPCFAGAMTLKPTHLDDSGAAHMVDVGAKPATQRRAVAAGRITMTAA
ALDAIRSGNAPKGDVLSTARIAGIMAAKRTADLIPLCHPLALTSVTVDFAWQTDGIAVTATAATSGPTGVEMEAFTAASV
ALLTLYDMAKALDRTMVIGDIRLLEKSGGRSGDWRAA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=54.6052631578947, Blast_Score=155, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32566331, Length=173, Percent_Identity=42.7745664739884, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28574490, Length=147, Percent_Identity=51.0204081632653, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=51.0948905109489, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 29157; Mature: 29157

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWGAAMKPSPLQGRGLGEGDHPNPSQLRLASKLASLRISPLKGREPLCPLPAGFRPSPL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SVRVERSRDTHRHQAMSRGISTSLDANGFYMLSCPQPAVPRQFLLLSPLAFRSPPCFAGA
EEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHCCCHHHCCCCCCCCE
MTLKPTHLDDSGAAHMVDVGAKPATQRRAVAAGRITMTAAALDAIRSGNAPKGDVLSTAR
EEECCCCCCCCCCEEEEECCCCCCHHHHHHHHCCEEHHHHHHHHHHCCCCCCCCHHHHHH
IAGIMAAKRTADLIPLCHPLALTSVTVDFAWQTDGIAVTATAATSGPTGVEMEAFTAASV
HHHHHHHHHHHHHHHHHCHHEEEEEEEEEEEECCCEEEEEEECCCCCCCCEEHHHHHHHH
ALLTLYDMAKALDRTMVIGDIRLLEKSGGRSGDWRAA
HHHHHHHHHHHHHHEEEEEHEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MEWGAAMKPSPLQGRGLGEGDHPNPSQLRLASKLASLRISPLKGREPLCPLPAGFRPSPL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SVRVERSRDTHRHQAMSRGISTSLDANGFYMLSCPQPAVPRQFLLLSPLAFRSPPCFAGA
EEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHCCCHHHCCCCCCCCE
MTLKPTHLDDSGAAHMVDVGAKPATQRRAVAAGRITMTAAALDAIRSGNAPKGDVLSTAR
EEECCCCCCCCCCEEEEECCCCCCHHHHHHHHCCEEHHHHHHHHHHCCCCCCCCHHHHHH
IAGIMAAKRTADLIPLCHPLALTSVTVDFAWQTDGIAVTATAATSGPTGVEMEAFTAASV
HHHHHHHHHHHHHHHHHCHHEEEEEEEEEEEECCCEEEEEEECCCCCCCCEEHHHHHHHH
ALLTLYDMAKALDRTMVIGDIRLLEKSGGRSGDWRAA
HHHHHHHHHHHHHHEEEEEHEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA