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The map label for this gene is ggt [H]

Identifier: 103486174

GI number: 103486174

Start: 689632

End: 691359

Strand: Direct

Name: ggt [H]

Synonym: Sala_0681

Alternate gene names: 103486174

Gene position: 689632-691359 (Clockwise)

Preceding gene: 103486173

Following gene: 103486175

Centisome position: 20.62

GC content: 67.13

Gene sequence:

>1728_bases
TTGCACTCCCTCTGTCTCCGCGCCAATGTCGCGTGCATGCTGAACCGTCTCCTCGCGCTCGTCGCCTTCGTCTCGCTTGC
CTGTCCCACGCTCGCCGCCGCTCAGGGCGTCACCTCCTCCGCCGATCCGCGCGCGACCGAGGCGGGGCGCGTCATCCTGC
ATCAGGGGGGCAGCGCCGCCGACGCTGCCATTGCCATGGTCGCGGTGCTCACGCTCGTCGAGCCGCAATCGAGCGGGATC
GGCGGTGGCGGCTTCATGCTCCATCACAATGCGGGCGACGGCGGCATATCGACGATCGACGGCCGCGAAACCGCACCCGC
CGCGGCGACCCCCGACCGCTTCCTCGGACCCGACGGCAAGCCGCGCGGCTTTATGGACGTGGTACCGGGCGGGCTTTCGG
TCGGGGTTCCGGGCAATATCCGCCTGATGGAAATGGCGCACAAAAAATGGGGCAAGCTCGAATGGAAGGCGCTGTTCCAG
CCGGCGATCGACCTTGCCGAAGGGGGTTTCGAGGTCACGCCCGCGCTCCACAACTGGCTCGTCCGGTTCGAGCCCGTCTG
GAAGGATTTTCCCGCGGCGCGTGCGATCTATCATGTCGATGGCAAGCCCGCGCCGGTCGGCACGCGGCTCCGCAACCCGG
CCTATGCCGCGCTGCTTCGCGACATCGCGGCGCGCGGCCCCGATGCTTTTTACAGGGGCGCCAATGCGCGCGCGATCCGC
GATGCGGTGGCCCGCGCGCCGCGCAATCCCGCGACGCTGACGCTTCAGGATCTCGCCTCCTATCGGGCCAGGGAACGCCC
CGCCGTCTGCACCAGCTATCGCATCTACAAGGTCTGCGGCATGGGTCCGCCCTCGTCGGGCGCCACCACCGTCTTCGGCA
TATTGGGGATGCTCGAAGGCTGGGACATGAAGGCGATGGGCAAGGACAATCCGATGAGCTGGCATCTGCTCGCCGAAGCG
ATGCAGCTCGCCTATGCCGATCGTGCCGCCTATCTTGGCGACGCCGACTTTGTCGATGTGCCGGTCAAAGGGCTGCTCGA
CAAATCCTATCTCGCCGAGCGCCGTCGGCTGATCTCGCCCTATGGCGCGGCGGGCCGTTACGAACCGGGCACGCCGCCGG
GGGCGACCCCGCGAGCCGCGGCGCCGCCGGTCGACGAGCAGGGGACGACACATTTCGTCGCCGCCGACGCTGCGGGCAAT
GTCGTCTCGATGACCTCGACGGTCGAAAGCATCTTCGGCAGCCAGCTGATTGCGAACGGCTATTTCCTCAACAATGAGCT
TACCGATTTCGATTTTGTGCCCGCCAGGGACGGGGTTCCGACCGCGAACCGGGTGCAGCCGGGCAAGCGGCCGCTGTCCT
CGATGTCGCCGACGATCGTTTACGGCCCCGACGGCAAGGTCGTGCTCGCGGTTGGTTCGGCGGGCGGCAAGCGTATCATC
ATGCACGTCACCAAGACGCTGATCGGCGTGCTCGACTGGGGCCTTGATGCGAAAGAGGCGATTGCGCTTCCCAACCTCTT
TTTCGGCCGCCAGGGCGTGCTGATCGAGGATAGTGAGGCGGGGCAGGCGATTGCCGCCAAAATGCAGCCTTTCGGCTACA
GCTTCACCCCCACCGACCTTGGATCGAAACTCAACGCGATCGAACGCACGGCGGAGGGAATGCGCGGCGCTGCCGATCCG
CGCGGTCCCGGCACCTCGGCCGTCGATGGCGCGCCGCCGCAGGGGTGA

Upstream 100 bases:

>100_bases
GGCGGCGCGCGACGGGTTTGCGCGGGTGAGCGACGCGGTGGGGGCGGGCGCCTGAGCCCATGCGCTCTCCCCCCGCAGCG
GAGAGAGCGATCAAGCGCCC

Downstream 100 bases:

>100_bases
ATGCGCCGCACTTGCCCGAATGCGCATCGGGTTATGGCTTCTAACGTACAGCGAATGACCCTAAGAACGGGGGCAACGAA
ATAATATCCTCCCGAGGAGA

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MHSLCLRANVACMLNRLLALVAFVSLACPTLAAAQGVTSSADPRATEAGRVILHQGGSAADAAIAMVAVLTLVEPQSSGI
GGGGFMLHHNAGDGGISTIDGRETAPAAATPDRFLGPDGKPRGFMDVVPGGLSVGVPGNIRLMEMAHKKWGKLEWKALFQ
PAIDLAEGGFEVTPALHNWLVRFEPVWKDFPAARAIYHVDGKPAPVGTRLRNPAYAALLRDIAARGPDAFYRGANARAIR
DAVARAPRNPATLTLQDLASYRARERPAVCTSYRIYKVCGMGPPSSGATTVFGILGMLEGWDMKAMGKDNPMSWHLLAEA
MQLAYADRAAYLGDADFVDVPVKGLLDKSYLAERRRLISPYGAAGRYEPGTPPGATPRAAAPPVDEQGTTHFVAADAAGN
VVSMTSTVESIFGSQLIANGYFLNNELTDFDFVPARDGVPTANRVQPGKRPLSSMSPTIVYGPDGKVVLAVGSAGGKRII
MHVTKTLIGVLDWGLDAKEAIALPNLFFGRQGVLIEDSEAGQAIAAKMQPFGYSFTPTDLGSKLNAIERTAEGMRGAADP
RGPGTSAVDGAPPQG

Sequences:

>Translated_575_residues
MHSLCLRANVACMLNRLLALVAFVSLACPTLAAAQGVTSSADPRATEAGRVILHQGGSAADAAIAMVAVLTLVEPQSSGI
GGGGFMLHHNAGDGGISTIDGRETAPAAATPDRFLGPDGKPRGFMDVVPGGLSVGVPGNIRLMEMAHKKWGKLEWKALFQ
PAIDLAEGGFEVTPALHNWLVRFEPVWKDFPAARAIYHVDGKPAPVGTRLRNPAYAALLRDIAARGPDAFYRGANARAIR
DAVARAPRNPATLTLQDLASYRARERPAVCTSYRIYKVCGMGPPSSGATTVFGILGMLEGWDMKAMGKDNPMSWHLLAEA
MQLAYADRAAYLGDADFVDVPVKGLLDKSYLAERRRLISPYGAAGRYEPGTPPGATPRAAAPPVDEQGTTHFVAADAAGN
VVSMTSTVESIFGSQLIANGYFLNNELTDFDFVPARDGVPTANRVQPGKRPLSSMSPTIVYGPDGKVVLAVGSAGGKRII
MHVTKTLIGVLDWGLDAKEAIALPNLFFGRQGVLIEDSEAGQAIAAKMQPFGYSFTPTDLGSKLNAIERTAEGMRGAADP
RGPGTSAVDGAPPQG
>Mature_575_residues
MHSLCLRANVACMLNRLLALVAFVSLACPTLAAAQGVTSSADPRATEAGRVILHQGGSAADAAIAMVAVLTLVEPQSSGI
GGGGFMLHHNAGDGGISTIDGRETAPAAATPDRFLGPDGKPRGFMDVVPGGLSVGVPGNIRLMEMAHKKWGKLEWKALFQ
PAIDLAEGGFEVTPALHNWLVRFEPVWKDFPAARAIYHVDGKPAPVGTRLRNPAYAALLRDIAARGPDAFYRGANARAIR
DAVARAPRNPATLTLQDLASYRARERPAVCTSYRIYKVCGMGPPSSGATTVFGILGMLEGWDMKAMGKDNPMSWHLLAEA
MQLAYADRAAYLGDADFVDVPVKGLLDKSYLAERRRLISPYGAAGRYEPGTPPGATPRAAAPPVDEQGTTHFVAADAAGN
VVSMTSTVESIFGSQLIANGYFLNNELTDFDFVPARDGVPTANRVQPGKRPLSSMSPTIVYGPDGKVVLAVGSAGGKRII
MHVTKTLIGVLDWGLDAKEAIALPNLFFGRQGVLIEDSEAGQAIAAKMQPFGYSFTPTDLGSKLNAIERTAEGMRGAADP
RGPGTSAVDGAPPQG

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=541, Percent_Identity=33.086876155268, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI73915090, Length=541, Percent_Identity=33.086876155268, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI73915096, Length=541, Percent_Identity=33.086876155268, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI73915094, Length=541, Percent_Identity=33.086876155268, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI113429324, Length=543, Percent_Identity=32.780847145488, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI113429326, Length=548, Percent_Identity=32.2992700729927, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI153266901, Length=529, Percent_Identity=28.5444234404537, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI153266885, Length=528, Percent_Identity=28.5984848484849, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI109148539, Length=549, Percent_Identity=30.4189435336976, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI153266907, Length=528, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI30581157, Length=191, Percent_Identity=36.1256544502618, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI30581155, Length=191, Percent_Identity=36.1256544502618, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1789856, Length=485, Percent_Identity=38.1443298969072, Blast_Score=286, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI193208247, Length=495, Percent_Identity=32.5252525252525, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193208245, Length=495, Percent_Identity=32.5252525252525, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17542894, Length=495, Percent_Identity=32.9292929292929, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI212646519, Length=500, Percent_Identity=32, Blast_Score=183, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI72000294, Length=500, Percent_Identity=32, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17506189, Length=487, Percent_Identity=31.4168377823409, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17564448, Length=431, Percent_Identity=27.6102088167053, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI72001497, Length=240, Percent_Identity=27.5, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI72001495, Length=240, Percent_Identity=27.5, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323330, Length=546, Percent_Identity=27.2893772893773, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI161077880, Length=555, Percent_Identity=30.0900900900901, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI45551474, Length=555, Percent_Identity=30.0900900900901, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI161077878, Length=555, Percent_Identity=30.0900900900901, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24642670, Length=555, Percent_Identity=30.0900900900901, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24642666, Length=555, Percent_Identity=30.0900900900901, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI18859893, Length=459, Percent_Identity=33.1154684095861, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI161077496, Length=465, Percent_Identity=33.1182795698925, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI18859741, Length=500, Percent_Identity=28.6, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 60463; Mature: 60463

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSLCLRANVACMLNRLLALVAFVSLACPTLAAAQGVTSSADPRATEAGRVILHQGGSAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHH
DAAIAMVAVLTLVEPQSSGIGGGGFMLHHNAGDGGISTIDGRETAPAAATPDRFLGPDGK
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCCCHHHCCCCCC
PRGFMDVVPGGLSVGVPGNIRLMEMAHKKWGKLEWKALFQPAIDLAEGGFEVTPALHNWL
CCCCCEECCCCEEECCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECHHHHHHH
VRFEPVWKDFPAARAIYHVDGKPAPVGTRLRNPAYAALLRDIAARGPDAFYRGANARAIR
EEECHHHHCCCCCCEEEEECCCCCCCCCHHCCHHHHHHHHHHHHCCCHHHHCCCCHHHHH
DAVARAPRNPATLTLQDLASYRARERPAVCTSYRIYKVCGMGPPSSGATTVFGILGMLEG
HHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCC
WDMKAMGKDNPMSWHLLAEAMQLAYADRAAYLGDADFVDVPVKGLLDKSYLAERRRLISP
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCC
YGAAGRYEPGTPPGATPRAAAPPVDEQGTTHFVAADAAGNVVSMTSTVESIFGSQLIANG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHCC
YFLNNELTDFDFVPARDGVPTANRVQPGKRPLSSMSPTIVYGPDGKVVLAVGSAGGKRII
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCCEEEEEECCCCCCHH
MHVTKTLIGVLDWGLDAKEAIALPNLFFGRQGVLIEDSEAGQAIAAKMQPFGYSFTPTDL
HHHHHHHHHHHHCCCCHHHHHCCCCHHCCCCCCEEECCCCCCHHHHHHCCCCCCCCHHHH
GSKLNAIERTAEGMRGAADPRGPGTSAVDGAPPQG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHSLCLRANVACMLNRLLALVAFVSLACPTLAAAQGVTSSADPRATEAGRVILHQGGSAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHH
DAAIAMVAVLTLVEPQSSGIGGGGFMLHHNAGDGGISTIDGRETAPAAATPDRFLGPDGK
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCCCHHHCCCCCC
PRGFMDVVPGGLSVGVPGNIRLMEMAHKKWGKLEWKALFQPAIDLAEGGFEVTPALHNWL
CCCCCEECCCCEEECCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECHHHHHHH
VRFEPVWKDFPAARAIYHVDGKPAPVGTRLRNPAYAALLRDIAARGPDAFYRGANARAIR
EEECHHHHCCCCCCEEEEECCCCCCCCCHHCCHHHHHHHHHHHHCCCHHHHCCCCHHHHH
DAVARAPRNPATLTLQDLASYRARERPAVCTSYRIYKVCGMGPPSSGATTVFGILGMLEG
HHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCC
WDMKAMGKDNPMSWHLLAEAMQLAYADRAAYLGDADFVDVPVKGLLDKSYLAERRRLISP
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCC
YGAAGRYEPGTPPGATPRAAAPPVDEQGTTHFVAADAAGNVVSMTSTVESIFGSQLIANG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHCC
YFLNNELTDFDFVPARDGVPTANRVQPGKRPLSSMSPTIVYGPDGKVVLAVGSAGGKRII
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCCEEEEEECCCCCCHH
MHVTKTLIGVLDWGLDAKEAIALPNLFFGRQGVLIEDSEAGQAIAAKMQPFGYSFTPTDL
HHHHHHHHHHHHCCCCHHHHHCCCCHHCCCCCCEEECCCCCCHHHHHHCCCCCCCCHHHH
GSKLNAIERTAEGMRGAADPRGPGTSAVDGAPPQG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA