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The map label for this gene is cysS [H]

Identifier: 103485844

GI number: 103485844

Start: 353461

End: 355044

Strand: Reverse

Name: cysS [H]

Synonym: Sala_0349

Alternate gene names: 103485844

Gene position: 355044-353461 (Counterclockwise)

Preceding gene: 103485845

Following gene: 103485843

Centisome position: 10.61

GC content: 61.3

Gene sequence:

>1584_bases
ATGGGCGGCGGCATGACCGACACGCCCGCCTCCCCGCCGCTGAGGCTGTTCAACAGCCTGACGCGCCGCCTCGAAACCTT
CGAGCCCGTCCACCCCGGCGAAGCGCGCGTCTACAGCTGCGGGCCGACCGTCTACAACTATCCGCATATCGGCAATATGC
GCGCCTATGTCTTTGCCGACACGCTGGGCCGCACCCTGTCGTTCAAGGGATACAAGCTCACCCATGTCATCAACATCACC
GATGTCGGTCATCTCACCGACGACGCCGATGCGGGGGAGGACAAGCTGGAAAAGGCCGCGGCCGAAAAGGCGCAGTCGAT
CTGGGACATCGCGCGCCATTATACCGAGGCCTATTGGGCCGACGTGAAGGCGCTGAACATCCGAGGCCCGATGAAGGCGG
GCAAGCCCGAGGCCGCGCACTGGTCGATCGCCACCGATTATGTGCCGCAGATGATCGAGTTCGCCAAAGCGATCGCCGAC
AAGCATTGCTATGAACTCGACAGTGGCCTCTATTTCGACACCTCGACCGTCGCCGATTACGGACGCCTTGCGCGCCATGC
GACCGACGAGGGCGAGAGCCGGATCGACCCTGTCGACGGCAAGCGCCATCCCGCCGACTTCGCCATCTGGCGCAAGACCC
CGCCGGGCGAGACGCGCCAGATGGAGTGGGACAGCCCATGGGGCAAAGGTGCGCCCGGCTGGCACCTCGAATGCTCGGTG
ATGTCGGAGGCTTTGCTCGGCTTCCCCTTCGACATCCACACCGGCGGCATCGACCACCGCGAGATTCATCATCCGAACGA
AATCGCACAGAACCAGGCGCGCAGCTGCTCGACCGACAGCGGCGCGCGCATCTGGATGCACAATAATTTCCTCGTCGAAC
GCTCTGGCAAGATGAGCAAGAGCGCGGGCGAGTTCCTGCGCCTGCAACTCCTGATCGACAAGGGCTACCACCCCCTCGCC
TATCGCCTGATGTGCCTCCAGGCGCATTATCGCAGCGAGCTGGAGTTTTCGTGGGAGGGGCTGGGCGCGGCGCTGACGCG
GTTGAAGCGGCTGGTGATGGCGGTCCAGCGCACTAAGGAGGCTGCCACGCTCTCCGAATGGAAACCGTTCAAAAAATACT
TGCGCAGTCCGGGCATGGTTGATGACTACATCGACTCCATCAATGAGACGGATGAATGGTTCGATTTTACCGGGATACTG
GGCGAATTTGACGATGCGATCAGCAATGATCTAAATACAGCATCGGCCTTCCCGACGTCGGAAAAACTGGCTTTGACTAA
GTTGGTCGAAGAAGCGGTCACTGACCCGTTTATTCAACTGGACAATCGCCTTCGCCTCATTGCTACGATGGACCAAATAT
TCGGTCTGCGACTTCTTGAATTGGATCGAATCGACCTGCGCATCCGCCCCAAAACTGCCACCATCACCGAATCCGAAATC
GAAGCCATCCTCACCCGCCGCAAGGAAGCCCGCGCCGCCAAGGACTTCGCGACCTCCGACAAACTCCGCGACGAACTCAT
CGCCGCCGGGGTCGAGGTGATGGACGGCGACCCGCTCGGCTGGGACTGGCGGCTGGAGGCATAG

Upstream 100 bases:

>100_bases
CTCGTCGACGATCCGGTGACCGGCGCGGGCAACGACGATCTGTGGACCCCGCCCGCGGAGTAAGCCGTCTTTCGGTTGAC
GTATCGCATCGGTGCGGGGC

Downstream 100 bases:

>100_bases
AATATCCTCCCCATCGACTTGCGATGGGGAGGTGGCAGCCCGCAGGGCTGACGGAGGGGCAACGACGGTGCGTCCAGACA
AACCCGCTTCGACGATCCGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MGGGMTDTPASPPLRLFNSLTRRLETFEPVHPGEARVYSCGPTVYNYPHIGNMRAYVFADTLGRTLSFKGYKLTHVINIT
DVGHLTDDADAGEDKLEKAAAEKAQSIWDIARHYTEAYWADVKALNIRGPMKAGKPEAAHWSIATDYVPQMIEFAKAIAD
KHCYELDSGLYFDTSTVADYGRLARHATDEGESRIDPVDGKRHPADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSV
MSEALLGFPFDIHTGGIDHREIHHPNEIAQNQARSCSTDSGARIWMHNNFLVERSGKMSKSAGEFLRLQLLIDKGYHPLA
YRLMCLQAHYRSELEFSWEGLGAALTRLKRLVMAVQRTKEAATLSEWKPFKKYLRSPGMVDDYIDSINETDEWFDFTGIL
GEFDDAISNDLNTASAFPTSEKLALTKLVEEAVTDPFIQLDNRLRLIATMDQIFGLRLLELDRIDLRIRPKTATITESEI
EAILTRRKEARAAKDFATSDKLRDELIAAGVEVMDGDPLGWDWRLEA

Sequences:

>Translated_527_residues
MGGGMTDTPASPPLRLFNSLTRRLETFEPVHPGEARVYSCGPTVYNYPHIGNMRAYVFADTLGRTLSFKGYKLTHVINIT
DVGHLTDDADAGEDKLEKAAAEKAQSIWDIARHYTEAYWADVKALNIRGPMKAGKPEAAHWSIATDYVPQMIEFAKAIAD
KHCYELDSGLYFDTSTVADYGRLARHATDEGESRIDPVDGKRHPADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSV
MSEALLGFPFDIHTGGIDHREIHHPNEIAQNQARSCSTDSGARIWMHNNFLVERSGKMSKSAGEFLRLQLLIDKGYHPLA
YRLMCLQAHYRSELEFSWEGLGAALTRLKRLVMAVQRTKEAATLSEWKPFKKYLRSPGMVDDYIDSINETDEWFDFTGIL
GEFDDAISNDLNTASAFPTSEKLALTKLVEEAVTDPFIQLDNRLRLIATMDQIFGLRLLELDRIDLRIRPKTATITESEI
EAILTRRKEARAAKDFATSDKLRDELIAAGVEVMDGDPLGWDWRLEA
>Mature_526_residues
GGGMTDTPASPPLRLFNSLTRRLETFEPVHPGEARVYSCGPTVYNYPHIGNMRAYVFADTLGRTLSFKGYKLTHVINITD
VGHLTDDADAGEDKLEKAAAEKAQSIWDIARHYTEAYWADVKALNIRGPMKAGKPEAAHWSIATDYVPQMIEFAKAIADK
HCYELDSGLYFDTSTVADYGRLARHATDEGESRIDPVDGKRHPADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSVM
SEALLGFPFDIHTGGIDHREIHHPNEIAQNQARSCSTDSGARIWMHNNFLVERSGKMSKSAGEFLRLQLLIDKGYHPLAY
RLMCLQAHYRSELEFSWEGLGAALTRLKRLVMAVQRTKEAATLSEWKPFKKYLRSPGMVDDYIDSINETDEWFDFTGILG
EFDDAISNDLNTASAFPTSEKLALTKLVEEAVTDPFIQLDNRLRLIATMDQIFGLRLLELDRIDLRIRPKTATITESEIE
AILTRRKEARAAKDFATSDKLRDELIAAGVEVMDGDPLGWDWRLEA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=333, Percent_Identity=34.8348348348348, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI10835051, Length=280, Percent_Identity=32.8571428571429, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI21269877, Length=280, Percent_Identity=32.8571428571429, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI303304987, Length=280, Percent_Identity=32.8571428571429, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI62240992, Length=280, Percent_Identity=32.8571428571429, Blast_Score=132, Evalue=9e-31,
Organism=Escherichia coli, GI1786737, Length=519, Percent_Identity=34.2967244701349, Blast_Score=230, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17509795, Length=259, Percent_Identity=31.6602316602317, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17509797, Length=259, Percent_Identity=31.6602316602317, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324082, Length=240, Percent_Identity=34.1666666666667, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI19922218, Length=511, Percent_Identity=28.9628180039139, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI19922364, Length=244, Percent_Identity=32.7868852459016, Blast_Score=125, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 59414; Mature: 59282

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGGMTDTPASPPLRLFNSLTRRLETFEPVHPGEARVYSCGPTVYNYPHIGNMRAYVFAD
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEH
TLGRTLSFKGYKLTHVINITDVGHLTDDADAGEDKLEKAAAEKAQSIWDIARHYTEAYWA
HHCCEEECCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKALNIRGPMKAGKPEAAHWSIATDYVPQMIEFAKAIADKHCYELDSGLYFDTSTVADY
CCEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHH
GRLARHATDEGESRIDPVDGKRHPADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSV
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEHHH
MSEALLGFPFDIHTGGIDHREIHHPNEIAQNQARSCSTDSGARIWMHNNFLVERSGKMSK
HHHHHHCCCCEECCCCCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCCCH
SAGEFLRLQLLIDKGYHPLAYRLMCLQAHYRSELEFSWEGLGAALTRLKRLVMAVQRTKE
HHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AATLSEWKPFKKYLRSPGMVDDYIDSINETDEWFDFTGILGEFDDAISNDLNTASAFPTS
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EKLALTKLVEEAVTDPFIQLDNRLRLIATMDQIFGLRLLELDRIDLRIRPKTATITESEI
HHHHHHHHHHHHHCCCHHHHCCCEEHHHHHHHHHCEEEEEECCCCEEEECCCCCCCHHHH
EAILTRRKEARAAKDFATSDKLRDELIAAGVEVMDGDPLGWDWRLEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEECC
>Mature Secondary Structure 
GGGMTDTPASPPLRLFNSLTRRLETFEPVHPGEARVYSCGPTVYNYPHIGNMRAYVFAD
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEH
TLGRTLSFKGYKLTHVINITDVGHLTDDADAGEDKLEKAAAEKAQSIWDIARHYTEAYWA
HHCCEEECCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKALNIRGPMKAGKPEAAHWSIATDYVPQMIEFAKAIADKHCYELDSGLYFDTSTVADY
CCEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHH
GRLARHATDEGESRIDPVDGKRHPADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSV
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEHHH
MSEALLGFPFDIHTGGIDHREIHHPNEIAQNQARSCSTDSGARIWMHNNFLVERSGKMSK
HHHHHHCCCCEECCCCCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCCCH
SAGEFLRLQLLIDKGYHPLAYRLMCLQAHYRSELEFSWEGLGAALTRLKRLVMAVQRTKE
HHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AATLSEWKPFKKYLRSPGMVDDYIDSINETDEWFDFTGILGEFDDAISNDLNTASAFPTS
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EKLALTKLVEEAVTDPFIQLDNRLRLIATMDQIFGLRLLELDRIDLRIRPKTATITESEI
HHHHHHHHHHHHHCCCHHHHCCCEEHHHHHHHHHCEEEEEECCCCEEEECCCCCCCHHHH
EAILTRRKEARAAKDFATSDKLRDELIAAGVEVMDGDPLGWDWRLEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA