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The map label for this gene is gpsA

Identifier: 103485695

GI number: 103485695

Start: 214037

End: 215038

Strand: Direct

Name: gpsA

Synonym: Sala_0199

Alternate gene names: 103485695

Gene position: 214037-215038 (Clockwise)

Preceding gene: 103485694

Following gene: 103485697

Centisome position: 6.4

GC content: 68.96

Gene sequence:

>1002_bases
ATGCGCCTCAAAGTGGGCCTGCTCGGCGGGGGCAGCTGGGGAACGACGGTCGCGGCGGTCGTGTCGCGCAACGCGCCGAT
CCAGCTATGGGCGCGCGACGCGGAAACGGTCGAGGGCATCAACCGCGATCACGAAAACCGCAAATATCTGCCCGGCATCA
CGCTGCCCCCCGCGCTCGGCGCGACCAGCGACATGGCCGAGGTCGTTGCGGGCGCCGACGTGCTCGTCATGGCGGTGCCC
TCGCACAGTTTCCGCAGCGTGTTGGAGGAGGCTCGCGATCATATCCGCCCGTGGGTGCCGGTCATCAGCCTCACGAAAGG
ACTCGAACTCGCCTCGGGCAAGCGCATGACCGAATTGATCGAGGACGTGCTGCCCGGCCACCCCGTCGGCGTGCTCACCG
GGCCCAACCTCGCGCGCGAGATCATGGCGGGACAGGCGGCGGCGAGCGTGCTCTCGATGGCGGACGAAATCGTCGTCCGT
GCGCTCCAGCCGCTGTTCCATTCGGGCCTGTTCCGCGTCTACACCAACACCGACCTGCTCGGCTGCGAGCTCGGCGGGGT
GCTCAAGAATATCATCGCGATCGCGGTGGGCATGGGCGACGGGCTCGGCGCCGGCGACAATACGCGCGCCGGCCTGATGA
CGCGCGGGCTGGCGGAGATCACGCGCCTCGGTGTCGCGATGGGCGGGCGCCCTGAAACCTTCGCCGGGCTCACCGGCATG
GGCGACCTGATCGCGACCTGCACCAGCCCCCTGTCGCGCAACCGCCACGTCGGCGTCGAACTCGGCAAGGGGCGCCCGAT
CGACGCGATCATCGCGGGCATGAACATGGTCGCGGAGGGCGTGAAAAGCGCGCCGACGGTTATGGCGCTCGCCGACCGCC
ACGGCATCGCGATGCCGATCGCGCGCGACGTGTTCGACGTGACGCAGGGCAAGCGAACGGCCATGGATGTCTTCCGCGGC
CTATTGAAATCGAGCGTCGGCGACGAGGCGCATCCGGGGTAG

Upstream 100 bases:

>100_bases
CGCCGACCATCCCTGAACTTCGCCGGGATGACGGGCGAGTGTTGCCTTGCCAACCCCCCGATCGCGCGCCACTCTCCCCT
GAAAAACAGGGGAGAGACAT

Downstream 100 bases:

>100_bases
CACAGCCTCCGTCATTGCGAGGAGCGTAGCGACGAAGCAATCTCCAGCTATCGGCCTGACAAGCCGATAGCTGGAGATTG
CTTCGCTTCGCTCGCAATGA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRLKVGLLGGGSWGTTVAAVVSRNAPIQLWARDAETVEGINRDHENRKYLPGITLPPALGATSDMAEVVAGADVLVMAVP
SHSFRSVLEEARDHIRPWVPVISLTKGLELASGKRMTELIEDVLPGHPVGVLTGPNLAREIMAGQAAASVLSMADEIVVR
ALQPLFHSGLFRVYTNTDLLGCELGGVLKNIIAIAVGMGDGLGAGDNTRAGLMTRGLAEITRLGVAMGGRPETFAGLTGM
GDLIATCTSPLSRNRHVGVELGKGRPIDAIIAGMNMVAEGVKSAPTVMALADRHGIAMPIARDVFDVTQGKRTAMDVFRG
LLKSSVGDEAHPG

Sequences:

>Translated_333_residues
MRLKVGLLGGGSWGTTVAAVVSRNAPIQLWARDAETVEGINRDHENRKYLPGITLPPALGATSDMAEVVAGADVLVMAVP
SHSFRSVLEEARDHIRPWVPVISLTKGLELASGKRMTELIEDVLPGHPVGVLTGPNLAREIMAGQAAASVLSMADEIVVR
ALQPLFHSGLFRVYTNTDLLGCELGGVLKNIIAIAVGMGDGLGAGDNTRAGLMTRGLAEITRLGVAMGGRPETFAGLTGM
GDLIATCTSPLSRNRHVGVELGKGRPIDAIIAGMNMVAEGVKSAPTVMALADRHGIAMPIARDVFDVTQGKRTAMDVFRG
LLKSSVGDEAHPG
>Mature_333_residues
MRLKVGLLGGGSWGTTVAAVVSRNAPIQLWARDAETVEGINRDHENRKYLPGITLPPALGATSDMAEVVAGADVLVMAVP
SHSFRSVLEEARDHIRPWVPVISLTKGLELASGKRMTELIEDVLPGHPVGVLTGPNLAREIMAGQAAASVLSMADEIVVR
ALQPLFHSGLFRVYTNTDLLGCELGGVLKNIIAIAVGMGDGLGAGDNTRAGLMTRGLAEITRLGVAMGGRPETFAGLTGM
GDLIATCTSPLSRNRHVGVELGKGRPIDAIIAGMNMVAEGVKSAPTVMALADRHGIAMPIARDVFDVTQGKRTAMDVFRG
LLKSSVGDEAHPG

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=286, Percent_Identity=31.1188811188811, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI24307999, Length=357, Percent_Identity=29.1316526610644, Blast_Score=133, Evalue=3e-31,
Organism=Escherichia coli, GI1790037, Length=326, Percent_Identity=38.6503067484663, Blast_Score=235, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17507425, Length=350, Percent_Identity=29.4285714285714, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32564399, Length=275, Percent_Identity=34.5454545454545, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI32564403, Length=284, Percent_Identity=33.8028169014084, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI193210136, Length=284, Percent_Identity=33.8028169014084, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193210134, Length=272, Percent_Identity=31.25, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324513, Length=289, Percent_Identity=31.1418685121107, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320181, Length=274, Percent_Identity=32.8467153284672, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17136204, Length=275, Percent_Identity=33.8181818181818, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17136202, Length=275, Percent_Identity=33.8181818181818, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17136200, Length=275, Percent_Identity=33.8181818181818, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI22026922, Length=356, Percent_Identity=27.8089887640449, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281362270, Length=237, Percent_Identity=30.8016877637131, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45551945, Length=237, Percent_Identity=30.8016877637131, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24648969, Length=225, Percent_Identity=30.6666666666667, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA2_SPHAL (Q1GWP9)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615256.1
- ProteinModelPortal:   Q1GWP9
- SMR:   Q1GWP9
- GeneID:   4082115
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0199
- NMPDR:   fig|317655.9.peg.179
- HOGENOM:   HBG586392
- OMA:   ASVIMEF
- ProtClustDB:   PRK12439
- BioCyc:   SALA317655:SALA_0199-MONOMER
- BRENDA:   1.1.1.94
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34828; Mature: 34828

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 189-189 BINDING 106-106 BINDING 106-106 BINDING 138-138 BINDING 253-253 BINDING 279-279

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKVGLLGGGSWGTTVAAVVSRNAPIQLWARDAETVEGINRDHENRKYLPGITLPPALG
CEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCC
ATSDMAEVVAGADVLVMAVPSHSFRSVLEEARDHIRPWVPVISLTKGLELASGKRMTELI
CCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHCCCHHHHHH
EDVLPGHPVGVLTGPNLAREIMAGQAAASVLSMADEIVVRALQPLFHSGLFRVYTNTDLL
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEE
GCELGGVLKNIIAIAVGMGDGLGAGDNTRAGLMTRGLAEITRLGVAMGGRPETFAGLTGM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCH
GDLIATCTSPLSRNRHVGVELGKGRPIDAIIAGMNMVAEGVKSAPTVMALADRHGIAMPI
HHHHHHHCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHH
ARDVFDVTQGKRTAMDVFRGLLKSSVGDEAHPG
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRLKVGLLGGGSWGTTVAAVVSRNAPIQLWARDAETVEGINRDHENRKYLPGITLPPALG
CEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCC
ATSDMAEVVAGADVLVMAVPSHSFRSVLEEARDHIRPWVPVISLTKGLELASGKRMTELI
CCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHCCCHHHHHH
EDVLPGHPVGVLTGPNLAREIMAGQAAASVLSMADEIVVRALQPLFHSGLFRVYTNTDLL
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEE
GCELGGVLKNIIAIAVGMGDGLGAGDNTRAGLMTRGLAEITRLGVAMGGRPETFAGLTGM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCH
GDLIATCTSPLSRNRHVGVELGKGRPIDAIIAGMNMVAEGVKSAPTVMALADRHGIAMPI
HHHHHHHCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHH
ARDVFDVTQGKRTAMDVFRGLLKSSVGDEAHPG
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA