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The map label for this gene is mmoC [H]

Identifier: 103485606

GI number: 103485606

Start: 107862

End: 108512

Strand: Direct

Name: mmoC [H]

Synonym: Sala_0109

Alternate gene names: 103485606

Gene position: 107862-108512 (Clockwise)

Preceding gene: 103485605

Following gene: 103485607

Centisome position: 3.22

GC content: 61.75

Gene sequence:

>651_bases
TTGAGCAGGCCGTTCGCGCACATCGCAGGCCAACATGTCGATGTCCGGCTGACCGCGCCTGATGGCTATAGCGCGATGCG
CAGTTACTCGATCGCGTCATCGGCAGCCTCGTCCCCGATCATCGAGCTCGCTGTCGAACGCCTGCCCGATGGCGAGGTGT
CGGCCTATTTTCACGATATCGCGATAGTCGGCGATGAGATCGAGCTTCGCGGTCCGCTCGGCGGGCACTTCCTATGGCCT
GAACCTGCCGTAGACGCGGTGCTGTTGATCGGAGCAGGCTCCGGGCTCGTGCCGTTGATGGCGATGATCCGGCATCGCCG
CACACAAGACCCGGCCGTGCCAACCGCGTTGCTCCTGTCCGCGCGCACCGCTGAGGATGTTCTGTTTTCGGAAGAACTAC
ATTCCGTCGAGATCAACGATGCCGCATTTGTCCTGGCGCTGGCGATCACGCGCGAAGATCCGATCCGCGCATCGGATTTC
GGGCGGCGGATCGACAGCGCCATGGTCGAAGAGGTTCTCGCCCGGCTTCACCGAAAGCCCACACAGATATTCGTTTGCGG
ATCCAACGATTTCGTCAACATTGCGACCGAGGGAGCGCTGCTGGCCGGGGTCGACCCCTCGATAATCAAGACCGAGCGCT
ATGGTGGTTAG

Upstream 100 bases:

>100_bases
ACCGATGACTGACAACGGCACGCAAACCGCGTCATGGCAATCATGCGTGATCGAGGAAATCGTCCAGCAGACGCCGAGCA
TCAAAAGCTTCTTCCTCCGA

Downstream 100 bases:

>100_bases
CGGCGCATACTCCGTCGCGCCCCACCTTTCACCCTGCGGATAATATTTGGAGATCGTCATGAGCCGCTTTGCTGAACCCG
TCTTTGTTGCCGCCGGCCTT

Product: oxidoreductase FAD-binding region

Products: NA

Alternate protein names: Methane hydroxylase; Methane monooxygenase reductase; MMOR [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSRPFAHIAGQHVDVRLTAPDGYSAMRSYSIASSAASSPIIELAVERLPDGEVSAYFHDIAIVGDEIELRGPLGGHFLWP
EPAVDAVLLIGAGSGLVPLMAMIRHRRTQDPAVPTALLLSARTAEDVLFSEELHSVEINDAAFVLALAITREDPIRASDF
GRRIDSAMVEEVLARLHRKPTQIFVCGSNDFVNIATEGALLAGVDPSIIKTERYGG

Sequences:

>Translated_216_residues
MSRPFAHIAGQHVDVRLTAPDGYSAMRSYSIASSAASSPIIELAVERLPDGEVSAYFHDIAIVGDEIELRGPLGGHFLWP
EPAVDAVLLIGAGSGLVPLMAMIRHRRTQDPAVPTALLLSARTAEDVLFSEELHSVEINDAAFVLALAITREDPIRASDF
GRRIDSAMVEEVLARLHRKPTQIFVCGSNDFVNIATEGALLAGVDPSIIKTERYGG
>Mature_215_residues
SRPFAHIAGQHVDVRLTAPDGYSAMRSYSIASSAASSPIIELAVERLPDGEVSAYFHDIAIVGDEIELRGPLGGHFLWPE
PAVDAVLLIGAGSGLVPLMAMIRHRRTQDPAVPTALLLSARTAEDVLFSEELHSVEINDAAFVLALAITREDPIRASDFG
RRIDSAMVEEVLARLHRKPTQIFVCGSNDFVNIATEGALLAGVDPSIIKTERYGG

Specific function: Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds. The component C is the iron-sulfur flavoprotein o

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=137, Percent_Identity=30.6569343065693, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: =1.14.13.25 [H]

Molecular weight: Translated: 23224; Mature: 23093

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPFAHIAGQHVDVRLTAPDGYSAMRSYSIASSAASSPIIELAVERLPDGEVSAYFHDI
CCCCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHEEEEE
AIVGDEIELRGPLGGHFLWPEPAVDAVLLIGAGSGLVPLMAMIRHRRTQDPAVPTALLLS
EEECCCEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHH
ARTAEDVLFSEELHSVEINDAAFVLALAITREDPIRASDFGRRIDSAMVEEVLARLHRKP
HCCHHHHHHHHHHCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TQIFVCGSNDFVNIATEGALLAGVDPSIIKTERYGG
CEEEEECCCCEEEEEECCEEEECCCCHHEECCCCCC
>Mature Secondary Structure 
SRPFAHIAGQHVDVRLTAPDGYSAMRSYSIASSAASSPIIELAVERLPDGEVSAYFHDI
CCCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHEEEEE
AIVGDEIELRGPLGGHFLWPEPAVDAVLLIGAGSGLVPLMAMIRHRRTQDPAVPTALLLS
EEECCCEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHH
ARTAEDVLFSEELHSVEINDAAFVLALAITREDPIRASDFGRRIDSAMVEEVLARLHRKP
HCCHHHHHHHHHHCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TQIFVCGSNDFVNIATEGALLAGVDPSIIKTERYGG
CEEEEECCCCEEEEEECCEEEECCCCHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1785954 [H]