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The map label for this gene is dsbD [H]

Identifier: 103485541

GI number: 103485541

Start: 42262

End: 44322

Strand: Reverse

Name: dsbD [H]

Synonym: Sala_0043

Alternate gene names: 103485541

Gene position: 44322-42262 (Counterclockwise)

Preceding gene: 103485544

Following gene: 103485540

Centisome position: 1.32

GC content: 69.38

Gene sequence:

>2061_bases
TTGGCGAGTGAGGCTTTTGTGACACGCATCGGACGGGCGCTGGCCGCCCTGCTCGCCGCCCTGTTGCTGGCCGCCGGTCC
GGCGCGGGCGCAGGCGACGCACATCTCGCCGCGACTGGTCGCCGAATCGGCGATGCCCGCGCCCGGTGGCACGACGACGC
TGGCGCTGACGATGACGCCCGAAAAGCCCTGGCACGGCTATTGGGTCAATGGCGGCGACGCGGGGTTCGGCCTGACGGTC
GAGTGGAACCTGCCCGACGGCGTGAGCGTCGCCCCCTTTCGCTACCCTGTGCCCGACGCGCTGATTCTCTTCGGCATGAT
GAACCATGTCTATGAGCATCCCTATGCGTTGCTCGCCGAACTCCGCGTCGACCGGTCGGTCGCGCCGGGCAGCGACCTCA
CCCTGTCGGGCGTCGCCAACTGGCTGGCCTGCACCGACAAGGTGTGCGTTCCCGAACGCGCGGTGATCTCGGTCGAGCTG
ACCGCGGGCGACGGGACGATTCCCGCCGGAGCGCGCGCGCGCTTCGACGGCTGGCGCGCCCTGCTGCCCCAGCCGCTCGA
CCGCGCGGGTCGCTGGGAGCGCCGCGGCGGCAGCGTGCGTTTCGCCATTCCGCTTCCCGCCAGCGTCGCGATCGACGCGC
CGCATCTGTTCGTCGAAACGCAGGATGTCATCGACTATGCCGCGCCGCAGCGTTTCAGCCGCCGCGGCGACCACATCATT
GTCGAGACGTCCGCCAAGGGGGCCCGCGAAGGGCCGGTGACGGCATTGCTCAGGACCGGCGAGGGACGCGGCCTGTCGCT
GAGGCTCGTGCCGGGCCCGGTGCCCGCCGCGGGCGAACCCGTTGCGACGGACGCGGCGGGCATAAACATGGGGCTGTTCT
GGACTGCGTTCGGCGGCGCAATTCTTGGCGGATTGATCCTCAACCTGATGCCCTGCGTCTTTCCGATTCTGAGTCTGAAG
GCGCTAAGCCTTGCGCGGTCGGGCGGCGACGCGCGGACAGCAAGAATCGAGGCGCTGGCCTATACCGCCGGCGCCATCCT
CACCGCCCTGCTGCTCGGCGGCGCCTTGCTCGCGCTGCGCGCGGCGGGCGAGCAGGTCGGCTGGGCATTCCAGCTTCAGC
ATCCGGTGAGCGTGCTCGCGCTGTTGCTCCTTGCACTCGCGATCACGCTCAATTTGCTTGGTTTCTACGAACTGCCCTCG
TTCAGCGGCGGTCAGGCGCTTGCGGATCAGGGCGGCGCAGCGGGCGGTTTCTGGACCGGCGCGCTCGCCGCCTTTGTCGC
AACACCGTGCAGCGGGCCACTGCTCGGCGCGGCGCTCGGCGCGACCCTGGCGCTGCCCGCATGGGCCGCGCTGCCGGTTT
TCGGCGGGCTCGGACTGGGGCTTGCCTTGCCCTTCCTCGCGATCGGCTTTGTCCCCGCGCTCCGGAATCGCCTGCCCAAG
CCGGGGCCGTGGATGAGCAGGTTTCGCCGCTGGATGGCGCTGCCGATGGGACTGACGACGCTCGCGCTGGTCTGGCTCCT
CTGGCGCCAGCTCGGCAACGGTGACCAGCTTATCTGGCCGGCGGTCGCGGTCGCCATGGCGCTCGTGCTGCTCACCCACT
ATGGCGCGATCCAGCGCGGCGACCGGCGATCGTGGCTGCTGATTGCGTCCGGTCTGCTCTTTACCGTCAGCCTTGGCGCC
ACGGTCGCCGAGGTGGCGAGGGCCGAACGCACCGCCGAGGGGAGCGGCTCAACCTTCTCCCCCGATGCACTCGCCAAGGC
GCGCGCGTCGGGCAAACCGGTCTTTGTCTATTTCACCGCCGACTGGTGCCTGTCGTGTAAAGCGAACGAGGCGGGCGCGA
TCAACCGCGCAGCTGTGCAGGCAGCGTTCGACAAGGCGGGGGTCGTCACGCTGGTCGGCGACTGGACGAACGGCGATCCG
GTCATCACGCGCACGCTGGCCGAGCACGGCCGCAACAGCGTGCCGCTCTACCTCTGGTATGCGCCGGGCGCGGATAAACC
CGAGATTTTGCCGCAGATCCTGACGCCGGGAATGCTGATCGATAAGGTTGGGGCCAAGTGA

Upstream 100 bases:

>100_bases
CGTCTCCATCGGGCGGGTGTCAGCGCGGGCTGTCCTCTCGACGAAAGCCGCCTATATGGCAAGCCTTCGAACGGCGAACG
GCCGCAGACGGAGCATGAAA

Downstream 100 bases:

>100_bases
TCGCCCTTGGTCGTCATTGCGAGCGCAGCGAAGCAATCTCCCGCTATCGCCCTGCCTTGCCGATAGCTGGAGATTGCTTC
GTCGCTTCGCTCCTCGCAAT

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MASEAFVTRIGRALAALLAALLLAAGPARAQATHISPRLVAESAMPAPGGTTTLALTMTPEKPWHGYWVNGGDAGFGLTV
EWNLPDGVSVAPFRYPVPDALILFGMMNHVYEHPYALLAELRVDRSVAPGSDLTLSGVANWLACTDKVCVPERAVISVEL
TAGDGTIPAGARARFDGWRALLPQPLDRAGRWERRGGSVRFAIPLPASVAIDAPHLFVETQDVIDYAAPQRFSRRGDHII
VETSAKGAREGPVTALLRTGEGRGLSLRLVPGPVPAAGEPVATDAAGINMGLFWTAFGGAILGGLILNLMPCVFPILSLK
ALSLARSGGDARTARIEALAYTAGAILTALLLGGALLALRAAGEQVGWAFQLQHPVSVLALLLLALAITLNLLGFYELPS
FSGGQALADQGGAAGGFWTGALAAFVATPCSGPLLGAALGATLALPAWAALPVFGGLGLGLALPFLAIGFVPALRNRLPK
PGPWMSRFRRWMALPMGLTTLALVWLLWRQLGNGDQLIWPAVAVAMALVLLTHYGAIQRGDRRSWLLIASGLLFTVSLGA
TVAEVARAERTAEGSGSTFSPDALAKARASGKPVFVYFTADWCLSCKANEAGAINRAAVQAAFDKAGVVTLVGDWTNGDP
VITRTLAEHGRNSVPLYLWYAPGADKPEILPQILTPGMLIDKVGAK

Sequences:

>Translated_686_residues
MASEAFVTRIGRALAALLAALLLAAGPARAQATHISPRLVAESAMPAPGGTTTLALTMTPEKPWHGYWVNGGDAGFGLTV
EWNLPDGVSVAPFRYPVPDALILFGMMNHVYEHPYALLAELRVDRSVAPGSDLTLSGVANWLACTDKVCVPERAVISVEL
TAGDGTIPAGARARFDGWRALLPQPLDRAGRWERRGGSVRFAIPLPASVAIDAPHLFVETQDVIDYAAPQRFSRRGDHII
VETSAKGAREGPVTALLRTGEGRGLSLRLVPGPVPAAGEPVATDAAGINMGLFWTAFGGAILGGLILNLMPCVFPILSLK
ALSLARSGGDARTARIEALAYTAGAILTALLLGGALLALRAAGEQVGWAFQLQHPVSVLALLLLALAITLNLLGFYELPS
FSGGQALADQGGAAGGFWTGALAAFVATPCSGPLLGAALGATLALPAWAALPVFGGLGLGLALPFLAIGFVPALRNRLPK
PGPWMSRFRRWMALPMGLTTLALVWLLWRQLGNGDQLIWPAVAVAMALVLLTHYGAIQRGDRRSWLLIASGLLFTVSLGA
TVAEVARAERTAEGSGSTFSPDALAKARASGKPVFVYFTADWCLSCKANEAGAINRAAVQAAFDKAGVVTLVGDWTNGDP
VITRTLAEHGRNSVPLYLWYAPGADKPEILPQILTPGMLIDKVGAK
>Mature_685_residues
ASEAFVTRIGRALAALLAALLLAAGPARAQATHISPRLVAESAMPAPGGTTTLALTMTPEKPWHGYWVNGGDAGFGLTVE
WNLPDGVSVAPFRYPVPDALILFGMMNHVYEHPYALLAELRVDRSVAPGSDLTLSGVANWLACTDKVCVPERAVISVELT
AGDGTIPAGARARFDGWRALLPQPLDRAGRWERRGGSVRFAIPLPASVAIDAPHLFVETQDVIDYAAPQRFSRRGDHIIV
ETSAKGAREGPVTALLRTGEGRGLSLRLVPGPVPAAGEPVATDAAGINMGLFWTAFGGAILGGLILNLMPCVFPILSLKA
LSLARSGGDARTARIEALAYTAGAILTALLLGGALLALRAAGEQVGWAFQLQHPVSVLALLLLALAITLNLLGFYELPSF
SGGQALADQGGAAGGFWTGALAAFVATPCSGPLLGAALGATLALPAWAALPVFGGLGLGLALPFLAIGFVPALRNRLPKP
GPWMSRFRRWMALPMGLTTLALVWLLWRQLGNGDQLIWPAVAVAMALVLLTHYGAIQRGDRRSWLLIASGLLFTVSLGAT
VAEVARAERTAEGSGSTFSPDALAKARASGKPVFVYFTADWCLSCKANEAGAINRAAVQAAFDKAGVVTLVGDWTNGDPV
ITRTLAEHGRNSVPLYLWYAPGADKPEILPQILTPGMLIDKVGAK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=400, Percent_Identity=29.25, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 71784; Mature: 71653

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEAFVTRIGRALAALLAALLLAAGPARAQATHISPRLVAESAMPAPGGTTTLALTMTP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEECC
EKPWHGYWVNGGDAGFGLTVEWNLPDGVSVAPFRYPVPDALILFGMMNHVYEHPYALLAE
CCCCCCEEECCCCCCEEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHH
LRVDRSVAPGSDLTLSGVANWLACTDKVCVPERAVISVELTAGDGTIPAGARARFDGWRA
HHHCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHH
LLPQPLDRAGRWERRGGSVRFAIPLPASVAIDAPHLFVETQDVIDYAAPQRFSRRGDHII
HCCCCHHHCCCHHHCCCCEEEEECCCCCEEECCCEEEEEHHHHHHHHCHHHHHCCCCEEE
VETSAKGAREGPVTALLRTGEGRGLSLRLVPGPVPAAGEPVATDAAGINMGLFWTAFGGA
EECCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ILGGLILNLMPCVFPILSLKALSLARSGGDARTARIEALAYTAGAILTALLLGGALLALR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGEQVGWAFQLQHPVSVLALLLLALAITLNLLGFYELPSFSGGQALADQGGAAGGFWTG
HCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHH
ALAAFVATPCSGPLLGAALGATLALPAWAALPVFGGLGLGLALPFLAIGFVPALRNRLPK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
PGPWMSRFRRWMALPMGLTTLALVWLLWRQLGNGDQLIWPAVAVAMALVLLTHYGAIQRG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCC
DRRSWLLIASGLLFTVSLGATVAEVARAERTAEGSGSTFSPDALAKARASGKPVFVYFTA
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEEC
DWCLSCKANEAGAINRAAVQAAFDKAGVVTLVGDWTNGDPVITRTLAEHGRNSVPLYLWY
CEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHEEHHHHHCCCCCCCEEEEE
APGADKPEILPQILTPGMLIDKVGAK
CCCCCCHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
ASEAFVTRIGRALAALLAALLLAAGPARAQATHISPRLVAESAMPAPGGTTTLALTMTP
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEECC
EKPWHGYWVNGGDAGFGLTVEWNLPDGVSVAPFRYPVPDALILFGMMNHVYEHPYALLAE
CCCCCCEEECCCCCCEEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHH
LRVDRSVAPGSDLTLSGVANWLACTDKVCVPERAVISVELTAGDGTIPAGARARFDGWRA
HHHCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHH
LLPQPLDRAGRWERRGGSVRFAIPLPASVAIDAPHLFVETQDVIDYAAPQRFSRRGDHII
HCCCCHHHCCCHHHCCCCEEEEECCCCCEEECCCEEEEEHHHHHHHHCHHHHHCCCCEEE
VETSAKGAREGPVTALLRTGEGRGLSLRLVPGPVPAAGEPVATDAAGINMGLFWTAFGGA
EECCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ILGGLILNLMPCVFPILSLKALSLARSGGDARTARIEALAYTAGAILTALLLGGALLALR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGEQVGWAFQLQHPVSVLALLLLALAITLNLLGFYELPSFSGGQALADQGGAAGGFWTG
HCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHH
ALAAFVATPCSGPLLGAALGATLALPAWAALPVFGGLGLGLALPFLAIGFVPALRNRLPK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
PGPWMSRFRRWMALPMGLTTLALVWLLWRQLGNGDQLIWPAVAVAMALVLLTHYGAIQRG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCC
DRRSWLLIASGLLFTVSLGATVAEVARAERTAEGSGSTFSPDALAKARASGKPVFVYFTA
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEEC
DWCLSCKANEAGAINRAAVQAAFDKAGVVTLVGDWTNGDPVITRTLAEHGRNSVPLYLWY
CEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHEEHHHHHCCCCCCCEEEEE
APGADKPEILPQILTPGMLIDKVGAK
CCCCCCHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA