Click here to switch to the map view.

The map label for this gene is hit [H]

Identifier: 197294739

GI number: 197294739

Start: 724109

End: 724522

Strand: Reverse

Name: hit [H]

Synonym: PAa_0705

Alternate gene names: 197294739

Gene position: 724522-724109 (Counterclockwise)

Preceding gene: 197294741

Following gene: 197294737

Centisome position: 82.34

GC content: 25.36

Gene sequence:

>414_bases
ATGTCAACTGTTTTTACTAAAATCATTCAAAAAGAAATCCCAAGTTATCCTTTATATGAAGATAATTTATTAATTGCCTT
TTTAGATATTACGCAAGCAACAAAAGGACACACTTTAGTTGTGACTAAAAAAGAATATCGCAACATTGAAGAAGTCCCTG
AAGAAGTTTTTATTCATCTATTTAAAATAGTTCATAAAATAAGCAAAGCATTAATTAAAACATTTCAATTACAAGGGATT
AATTTATTAAATAATAATGGTAGTGTTGCAGGACAAACAGTTTTTCATTATCATGTTCACTTGCTTCCTCGGTTTTGCAA
AAAAGAAATTGGAGTTATGTTAAAAAATAACGCTAATAATTTAAAAATTTCAGATTATAAAAAGGTTCAACAAGCTATTT
TAATGAATTTATAA

Upstream 100 bases:

>100_bases
TTATTGTTAATCAATTATTAAATAAAATTACCAGTTTTTTTGATAAGTTAACGATTTCAAATATAAAACTAAATGGTAAT
AGACATGAAAGGAATTTATT

Downstream 100 bases:

>100_bases
AAATTATCATTTTCACATTTTTTATTTTTTAAGAAATTAAAAAAAAATGCAGACTTATTTTTAACCTTTGTCAAAATAGT
GATTATATTTTTGTTCTTTT

Product: Diadenosine tetraphosphate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MSTVFTKIIQKEIPSYPLYEDNLLIAFLDITQATKGHTLVVTKKEYRNIEEVPEEVFIHLFKIVHKISKALIKTFQLQGI
NLLNNNGSVAGQTVFHYHVHLLPRFCKKEIGVMLKNNANNLKISDYKKVQQAILMNL

Sequences:

>Translated_137_residues
MSTVFTKIIQKEIPSYPLYEDNLLIAFLDITQATKGHTLVVTKKEYRNIEEVPEEVFIHLFKIVHKISKALIKTFQLQGI
NLLNNNGSVAGQTVFHYHVHLLPRFCKKEIGVMLKNNANNLKISDYKKVQQAILMNL
>Mature_136_residues
STVFTKIIQKEIPSYPLYEDNLLIAFLDITQATKGHTLVVTKKEYRNIEEVPEEVFIHLFKIVHKISKALIKTFQLQGIN
LLNNNGSVAGQTVFHYHVHLLPRFCKKEIGVMLKNNANNLKISDYKKVQQAILMNL

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=104, Percent_Identity=36.5384615384615, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320078, Length=136, Percent_Identity=32.3529411764706, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15779; Mature: 15648

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVFTKIIQKEIPSYPLYEDNLLIAFLDITQATKGHTLVVTKKEYRNIEEVPEEVFIHL
CHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEEEECHHHCCHHHHHHHHHHHH
FKIVHKISKALIKTFQLQGINLLNNNGSVAGQTVFHYHVHLLPRFCKKEIGVMLKNNANN
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCC
LKISDYKKVQQAILMNL
CEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
STVFTKIIQKEIPSYPLYEDNLLIAFLDITQATKGHTLVVTKKEYRNIEEVPEEVFIHL
HHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEEEECHHHCCHHHHHHHHHHHH
FKIVHKISKALIKTFQLQGINLLNNNGSVAGQTVFHYHVHLLPRFCKKEIGVMLKNNANN
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCC
LKISDYKKVQQAILMNL
CEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]