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The map label for this gene is 197294682

Identifier: 197294682

GI number: 197294682

Start: 638539

End: 640107

Strand: Reverse

Name: 197294682

Synonym: PAa_0640

Alternate gene names: NA

Gene position: 640107-638539 (Counterclockwise)

Preceding gene: 197294683

Following gene: 197294681

Centisome position: 72.74

GC content: 30.21

Gene sequence:

>1569_bases
GTGTCATGCGGGTTTAATACGATTTTTATTCCTGTTGTTTTTTTTTCTTTAGGTATATCAACTGGTTATTTATTTTATTA
TTTCTTTAATCGTAAAAAAATCCATCAAGAACAAGCCAAATTCAAAAAACAAGTTCAAGAAAAGTCAGAAGAACTTGAAA
CATACGGAAAAGAAATAGTTAGAAATGCCAAAATAGAAATATCCGCATTAAGAAATAAAATGGAACGTGATTTGCATGAA
AGAACTAATATTATAGTTAAATTAGAAGAAAAAAACAATCGTCGTGAAGAATTGTTTAACAATAGAACAGAAAACTTAAA
TAAAAGAGAACAATATTTAGATGAAGAGTTACGAAAAATTAATTATACTAAAAATAAGCTAGAAATGCAGATCAAAGAAC
AAGAAATTATTTCACAAAATCAAAAAAACAAACTAGAACAAATAGCTTCTTTAAACCAAGAAGAAGCTAAAAAAATTATT
ATGGAAGAAGTTAGAAATAAGACTGCTAATGAAATTTTTATGTATATCAAAAAAGAAGAAGAAAAAGCGAAATTAGAAGT
TTCTAAAAAAGCCAAAATGCTTTTGATTTCAACGATGCAAAGTTATTCTTCTGATATTACAGGAGAAAAAAATATTAGTG
TTGTTGATATCCCTAATGAAGAAATGAAAGGCCGTATTATTGGTCGTCAAGGAAGAAACATTAAAGCTTTAGAAGTTTTG
ACAGGGGTAGATTTAATTATCGACGAATCTCCTTTAACGGTAGTTTTAAGTAGTTTTAATCCTGTTAGAAGAGAAATTGC
TAAAAAAACTTTAGAATTACTAGTTTTAGATGGCAGAATTCATCCTTCTCGTATCGAAAAAGCGTTAGAACAATCAACTT
CAGAAGTTAATAATTTTATCAAAGAATTAGGCGAAGAAGCTGTTTTTATGACTAAAATCGGCGAAGTTCATCCTGATTTA
ATTCAACTTTTAGGAAAATTACATTTTCGTTTAAGTTATACTCAAAATGTTTTAAAACATTCTTTGGAAGTTGCTTTTTT
GGCAGGAAAACTAGCAGCAGAATTGGGAGAAGACGAAATTATTGCCAGAAGAGCAGGGCTTTTTCATGATATCGGTAAGG
CCTTAGATCATGAAATGGAAGGTGGTCATGTTGAAATCGGAACTGCTTTAGCTTATAAATATAAAGAAAAAAAAGAAGTT
ATTGATGCTATTGCTTCTCACCATGAAGATCAAGTTGCAGATACAACAATTGGAGCTTTAGTTGCTATCGCAGATACTCT
CAGTGCAGCAAGACCCGGAGCCAGAAAAGAATCAATCGAAAATTATATCCAAAGATTAACTAAATTAGAAAGCATTGCAA
ACTCTATCAAAGGAGTTGCTCAATCTTACGCTGTACAAGCTGGTCGTGAAATTAGAGTCATTGTTAAACCAGAAGCAATC
AACGACCATTTTATGTCTTCAATTGCAAGAACAATTAAAGAACAAATAGAAAAAGATATTAGTTATAATGGAGTTATCAA
AGTTACTGTTATAAGAGAAACAAGAGCCATTGAACTAGCTAGATTCTAG

Upstream 100 bases:

>100_bases
TTATTTCTTTATTTATCATATTAAAAAATTATTTTCATATGATTTAATGAATCATAAAACAATCAATAAAAAGATTATAA
AAAAGAAAGGTATAAATCAA

Downstream 100 bases:

>100_bases
TGAATGAGGAGAATGATTGTGAAAATAATGTTTATTGGAGATATTTATGGCAAACCAGGAATGGATTATTTTTCAGAAAA
CATAGATTTTTTAAAAAAAA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MSCGFNTIFIPVVFFSLGISTGYLFYYFFNRKKIHQEQAKFKKQVQEKSEELETYGKEIVRNAKIEISALRNKMERDLHE
RTNIIVKLEEKNNRREELFNNRTENLNKREQYLDEELRKINYTKNKLEMQIKEQEIISQNQKNKLEQIASLNQEEAKKII
MEEVRNKTANEIFMYIKKEEEKAKLEVSKKAKMLLISTMQSYSSDITGEKNISVVDIPNEEMKGRIIGRQGRNIKALEVL
TGVDLIIDESPLTVVLSSFNPVRREIAKKTLELLVLDGRIHPSRIEKALEQSTSEVNNFIKELGEEAVFMTKIGEVHPDL
IQLLGKLHFRLSYTQNVLKHSLEVAFLAGKLAAELGEDEIIARRAGLFHDIGKALDHEMEGGHVEIGTALAYKYKEKKEV
IDAIASHHEDQVADTTIGALVAIADTLSAARPGARKESIENYIQRLTKLESIANSIKGVAQSYAVQAGREIRVIVKPEAI
NDHFMSSIARTIKEQIEKDISYNGVIKVTVIRETRAIELARF

Sequences:

>Translated_522_residues
MSCGFNTIFIPVVFFSLGISTGYLFYYFFNRKKIHQEQAKFKKQVQEKSEELETYGKEIVRNAKIEISALRNKMERDLHE
RTNIIVKLEEKNNRREELFNNRTENLNKREQYLDEELRKINYTKNKLEMQIKEQEIISQNQKNKLEQIASLNQEEAKKII
MEEVRNKTANEIFMYIKKEEEKAKLEVSKKAKMLLISTMQSYSSDITGEKNISVVDIPNEEMKGRIIGRQGRNIKALEVL
TGVDLIIDESPLTVVLSSFNPVRREIAKKTLELLVLDGRIHPSRIEKALEQSTSEVNNFIKELGEEAVFMTKIGEVHPDL
IQLLGKLHFRLSYTQNVLKHSLEVAFLAGKLAAELGEDEIIARRAGLFHDIGKALDHEMEGGHVEIGTALAYKYKEKKEV
IDAIASHHEDQVADTTIGALVAIADTLSAARPGARKESIENYIQRLTKLESIANSIKGVAQSYAVQAGREIRVIVKPEAI
NDHFMSSIARTIKEQIEKDISYNGVIKVTVIRETRAIELARF
>Mature_521_residues
SCGFNTIFIPVVFFSLGISTGYLFYYFFNRKKIHQEQAKFKKQVQEKSEELETYGKEIVRNAKIEISALRNKMERDLHER
TNIIVKLEEKNNRREELFNNRTENLNKREQYLDEELRKINYTKNKLEMQIKEQEIISQNQKNKLEQIASLNQEEAKKIIM
EEVRNKTANEIFMYIKKEEEKAKLEVSKKAKMLLISTMQSYSSDITGEKNISVVDIPNEEMKGRIIGRQGRNIKALEVLT
GVDLIIDESPLTVVLSSFNPVRREIAKKTLELLVLDGRIHPSRIEKALEQSTSEVNNFIKELGEEAVFMTKIGEVHPDLI
QLLGKLHFRLSYTQNVLKHSLEVAFLAGKLAAELGEDEIIARRAGLFHDIGKALDHEMEGGHVEIGTALAYKYKEKKEVI
DAIASHHEDQVADTTIGALVAIADTLSAARPGARKESIENYIQRLTKLESIANSIKGVAQSYAVQAGREIRVIVKPEAIN
DHFMSSIARTIKEQIEKDISYNGVIKVTVIRETRAIELARF

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA [H]

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675 [H]

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1 [H]

EC number: =3.1.4.16 [H]

Molecular weight: Translated: 59689; Mature: 59557

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCGFNTIFIPVVFFSLGISTGYLFYYFFNRKKIHQEQAKFKKQVQEKSEELETYGKEIV
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNAKIEISALRNKMERDLHERTNIIVKLEEKNNRREELFNNRTENLNKREQYLDEELRKI
HCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCHHCCCHHHHHHHHHHHHHC
NYTKNKLEMQIKEQEIISQNQKNKLEQIASLNQEEAKKIIMEEVRNKTANEIFMYIKKEE
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHEEEEECCH
EKAKLEVSKKAKMLLISTMQSYSSDITGEKNISVVDIPNEEMKGRIIGRQGRNIKALEVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHCCCEECCCCCCEEHHHHH
TGVDLIIDESPLTVVLSSFNPVRREIAKKTLELLVLDGRIHPSRIEKALEQSTSEVNNFI
HCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
KELGEEAVFMTKIGEVHPDLIQLLGKLHFRLSYTQNVLKHSLEVAFLAGKLAAELGEDEI
HHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IARRAGLFHDIGKALDHEMEGGHVEIGTALAYKYKEKKEVIDAIASHHEDQVADTTIGAL
HHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VAIADTLSAARPGARKESIENYIQRLTKLESIANSIKGVAQSYAVQAGREIRVIVKPEAI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
NDHFMSSIARTIKEQIEKDISYNGVIKVTVIRETRAIELARF
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHCCC
>Mature Secondary Structure 
SCGFNTIFIPVVFFSLGISTGYLFYYFFNRKKIHQEQAKFKKQVQEKSEELETYGKEIV
CCCCHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNAKIEISALRNKMERDLHERTNIIVKLEEKNNRREELFNNRTENLNKREQYLDEELRKI
HCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCHHCCCHHHHHHHHHHHHHC
NYTKNKLEMQIKEQEIISQNQKNKLEQIASLNQEEAKKIIMEEVRNKTANEIFMYIKKEE
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHEEEEECCH
EKAKLEVSKKAKMLLISTMQSYSSDITGEKNISVVDIPNEEMKGRIIGRQGRNIKALEVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHCCCEECCCCCCEEHHHHH
TGVDLIIDESPLTVVLSSFNPVRREIAKKTLELLVLDGRIHPSRIEKALEQSTSEVNNFI
HCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
KELGEEAVFMTKIGEVHPDLIQLLGKLHFRLSYTQNVLKHSLEVAFLAGKLAAELGEDEI
HHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IARRAGLFHDIGKALDHEMEGGHVEIGTALAYKYKEKKEVIDAIASHHEDQVADTTIGAL
HHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VAIADTLSAARPGARKESIENYIQRLTKLESIANSIKGVAQSYAVQAGREIRVIVKPEAI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
NDHFMSSIARTIKEQIEKDISYNGVIKVTVIRETRAIELARF
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA