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The map label for this gene is efp

Identifier: 197294679

GI number: 197294679

Start: 636186

End: 636755

Strand: Reverse

Name: efp

Synonym: PAa_0637

Alternate gene names: 197294679

Gene position: 636755-636186 (Counterclockwise)

Preceding gene: 197294680

Following gene: 197294678

Centisome position: 72.36

GC content: 26.67

Gene sequence:

>570_bases
ATGATTAATACAAATGATTTTAAAACAGGTCAAACAATTAAATTTAACAATCAAATTTATCAAATTATTGAGTTTTTACA
CGTAAAACCTGGAAAAGGAACTGCTTTTGTAAGAAGTAAATTAAGAAATTTAAGAACAGGAAGTGTTATCGATCACACTT
TTAACGCTGGTATTAAATTAGAACCTGCTTTGATTAACAAAATCAAAATGCAATTCCTTTATTCTTCTCAAGAAAAATAT
ATTTTTATGAATACCCAAACATATGAGCAGTTAGAAATCAACAAAGATCAATTAAAAGAAAAACTTCATTATCTTTACGA
AGGGTTATTGGTAGAAATTATTTTTTACAATAATAATGAAATTTTAACAATCAGTTTACCTGATAAAATTTCTCTTAAAG
TCACTTATGCAGAACCAGGAGTTAAAGGGGATACTAAGACCAATTCCTTTAAAGATGCTACTTTGGAAACAGGATTAGTT
ATTAAAGTTCCTCTTTTTATTAATACAGGCGAAAAGATTATTGTTAATACAGAGACTGGATTGTATTTATCCAGAGACAA
TAACAAATAA

Upstream 100 bases:

>100_bases
AAACCAATTGCAACCGGTTGTTGTAGATGCTTTATCCCCTTCTTTAGAAAAAAAAGTTTTTCAATTAGTCTTTGATTTTT
TGCACAAAAGGAGTTAAAAT

Downstream 100 bases:

>100_bases
TTTTAATTTTATTAGTTTTAACTTTTTATTTTTTTGAAAACGATTTTTGTTATATAATGAAAATAGTTGTTAGAAAAAAT
TAATTAAAAGAAATAAAGGA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MINTNDFKTGQTIKFNNQIYQIIEFLHVKPGKGTAFVRSKLRNLRTGSVIDHTFNAGIKLEPALINKIKMQFLYSSQEKY
IFMNTQTYEQLEINKDQLKEKLHYLYEGLLVEIIFYNNNEILTISLPDKISLKVTYAEPGVKGDTKTNSFKDATLETGLV
IKVPLFINTGEKIIVNTETGLYLSRDNNK

Sequences:

>Translated_189_residues
MINTNDFKTGQTIKFNNQIYQIIEFLHVKPGKGTAFVRSKLRNLRTGSVIDHTFNAGIKLEPALINKIKMQFLYSSQEKY
IFMNTQTYEQLEINKDQLKEKLHYLYEGLLVEIIFYNNNEILTISLPDKISLKVTYAEPGVKGDTKTNSFKDATLETGLV
IKVPLFINTGEKIIVNTETGLYLSRDNNK
>Mature_189_residues
MINTNDFKTGQTIKFNNQIYQIIEFLHVKPGKGTAFVRSKLRNLRTGSVIDHTFNAGIKLEPALINKIKMQFLYSSQEKY
IFMNTQTYEQLEINKDQLKEKLHYLYEGLLVEIIFYNNNEILTISLPDKISLKVTYAEPGVKGDTKTNSFKDATLETGLV
IKVPLFINTGEKIIVNTETGLYLSRDNNK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=36.8131868131868, Blast_Score=130, Evalue=4e-32,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=27.1276595744681, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_PHYAS (B1VAJ8)

Other databases:

- EMBL:   AM422018
- RefSeq:   YP_001799220.1
- ProteinModelPortal:   B1VAJ8
- SMR:   B1VAJ8
- GeneID:   6798929
- GenomeReviews:   AM422018_GR
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21703; Mature: 21703

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTNDFKTGQTIKFNNQIYQIIEFLHVKPGKGTAFVRSKLRNLRTGSVIDHTFNAGIKL
CCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEE
EPALINKIKMQFLYSSQEKYIFMNTQTYEQLEINKDQLKEKLHYLYEGLLVEIIFYNNNE
CHHHHHHHHEEEEECCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHCEEEEEEEECCCE
ILTISLPDKISLKVTYAEPGVKGDTKTNSFKDATLETGLVIKVPLFINTGEKIIVNTETG
EEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCEECCCEEEEEEEEEECCCEEEEECCCC
LYLSRDNNK
EEEECCCCC
>Mature Secondary Structure
MINTNDFKTGQTIKFNNQIYQIIEFLHVKPGKGTAFVRSKLRNLRTGSVIDHTFNAGIKL
CCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEE
EPALINKIKMQFLYSSQEKYIFMNTQTYEQLEINKDQLKEKLHYLYEGLLVEIIFYNNNE
CHHHHHHHHEEEEECCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHCEEEEEEEECCCE
ILTISLPDKISLKVTYAEPGVKGDTKTNSFKDATLETGLVIKVPLFINTGEKIIVNTETG
EEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCEECCCEEEEEEEEEECCCEEEEECCCC
LYLSRDNNK
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA