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The map label for this gene is pgk [H]

Identifier: 197294556

GI number: 197294556

Start: 504566

End: 505771

Strand: Reverse

Name: pgk [H]

Synonym: PAa_0511

Alternate gene names: 197294556

Gene position: 505771-504566 (Counterclockwise)

Preceding gene: 197294557

Following gene: 197294555

Centisome position: 57.48

GC content: 31.26

Gene sequence:

>1206_bases
ATGAAGAATCAATTAACTAATTTAAAGATCGAAAATAAAAAAGTTTTATTGCGGGCTGATTTGAATGTGCCTTTAGAAAA
CAATGTCATTACAGACGATAACCGAATTAAGGCTATTTTGCCAACTTTGCAATATTTAATCGAAAAAAAAGCCAAAATAA
TTGTTTTATCTCACTTGGGAAGAATCAAAGAAGAATCCCAAAAAGCCCATTTTAGTTTAAAATCTGTAGCTGATAAATTA
TCTTTTTATTTAAAACAAAAAGTTGTTTTCGTACCAGCAACAAAAGGTAGGCTTGTGGAAGATGCTATCAATAAATTAAT
CCCTGGCGAAGTTATGATGCTTGAAAACACTCGTTTTGAAGATCTAGATAATAAAGCTGAAAGCAAAAATAATCCTCAGT
TAGGTCAATATTGGGCTTCTTTGGGTGATGTTTTTGTTAATGATGCTTTTGGTACTTGTCATCGAACTCACGCCTCTAAT
GTAGGGATTGCAAATAATATCAAAGAAAAATGTTTTGGTTTTTTGGTTGAAAAAGAAATCAATTTCATTCAAAAAATCAT
TTCCAATCCACAAAGACCATTAATAGCAATTTTGGGTGGTTCCAAAGTATCTGATAAAATAGAGTTAATTAAAAATATGT
TAAAAAAAGTGGATTTTCTTTTGATTGGCGGAGGAATGAGTTACACTTTTTTAAAAACTCAAGGATTTGAAGTTGGTACA
AGTCTATTAGAGGCAGATAAAATACCATTAGTAAAAGATTTGTTATCTTCTCCTGAAGCTAAAAAAATCATTTTACCAAA
AGATTTTGTTTGTGGAAAAGAATTTTCTCCAAATACTGAATCGGCAATTTATAAATGTTTTAATATTCCTAATAATTTTA
TGGGAATGGACATTGGACCAGAAACTATCCAACTTTTTAAACATTATTTAACAAAGGCTAAAACAATTGTTTGGAATGGC
CCTGTAGGTGTTTTCGAATTTGAAAAATTTAGCCATGGAACTAAAAGCATAGCTCAAATAATTAGCTCATTACTTTCTTC
AACAACGACAATTATTGGCGGTGGTGATAGTGCTGCAGCGGTGTTTAAATTTGGTCTGGAAAAACATTTCAGTCATATTT
CAACTGGTGGGGGAGCTTTTTTAGAATTTTTAGAAGGAAAACCCATGCCAGGACTTGCATGCATTCAAGACATCAAAGAA
TCATAA

Upstream 100 bases:

>100_bases
TTTTTAGCGATTAAAGAAGAAATTAAACGCAAATTAACTCTTTTTGGTTCCGTCAACAAAGCTTAAAATAAAAAAAATTA
AAATAAAAGGTATAATTGTT

Downstream 100 bases:

>100_bases
TTTTTTATCAAAAAAAATAATTAAATAAAAAAATAAAAAAAAGAGGTTTTAATAATTATGAAAGTTAGAGTAGCAATTAA
TGGTTTTGGCCGCATCGGAA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKNQLTNLKIENKKVLLRADLNVPLENNVITDDNRIKAILPTLQYLIEKKAKIIVLSHLGRIKEESQKAHFSLKSVADKL
SFYLKQKVVFVPATKGRLVEDAINKLIPGEVMMLENTRFEDLDNKAESKNNPQLGQYWASLGDVFVNDAFGTCHRTHASN
VGIANNIKEKCFGFLVEKEINFIQKIISNPQRPLIAILGGSKVSDKIELIKNMLKKVDFLLIGGGMSYTFLKTQGFEVGT
SLLEADKIPLVKDLLSSPEAKKIILPKDFVCGKEFSPNTESAIYKCFNIPNNFMGMDIGPETIQLFKHYLTKAKTIVWNG
PVGVFEFEKFSHGTKSIAQIISSLLSSTTTIIGGGDSAAAVFKFGLEKHFSHISTGGGAFLEFLEGKPMPGLACIQDIKE
S

Sequences:

>Translated_401_residues
MKNQLTNLKIENKKVLLRADLNVPLENNVITDDNRIKAILPTLQYLIEKKAKIIVLSHLGRIKEESQKAHFSLKSVADKL
SFYLKQKVVFVPATKGRLVEDAINKLIPGEVMMLENTRFEDLDNKAESKNNPQLGQYWASLGDVFVNDAFGTCHRTHASN
VGIANNIKEKCFGFLVEKEINFIQKIISNPQRPLIAILGGSKVSDKIELIKNMLKKVDFLLIGGGMSYTFLKTQGFEVGT
SLLEADKIPLVKDLLSSPEAKKIILPKDFVCGKEFSPNTESAIYKCFNIPNNFMGMDIGPETIQLFKHYLTKAKTIVWNG
PVGVFEFEKFSHGTKSIAQIISSLLSSTTTIIGGGDSAAAVFKFGLEKHFSHISTGGGAFLEFLEGKPMPGLACIQDIKE
S
>Mature_401_residues
MKNQLTNLKIENKKVLLRADLNVPLENNVITDDNRIKAILPTLQYLIEKKAKIIVLSHLGRIKEESQKAHFSLKSVADKL
SFYLKQKVVFVPATKGRLVEDAINKLIPGEVMMLENTRFEDLDNKAESKNNPQLGQYWASLGDVFVNDAFGTCHRTHASN
VGIANNIKEKCFGFLVEKEINFIQKIISNPQRPLIAILGGSKVSDKIELIKNMLKKVDFLLIGGGMSYTFLKTQGFEVGT
SLLEADKIPLVKDLLSSPEAKKIILPKDFVCGKEFSPNTESAIYKCFNIPNNFMGMDIGPETIQLFKHYLTKAKTIVWNG
PVGVFEFEKFSHGTKSIAQIISSLLSSTTTIIGGGDSAAAVFKFGLEKHFSHISTGGGAFLEFLEGKPMPGLACIQDIKE
S

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=417, Percent_Identity=43.8848920863309, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI31543397, Length=411, Percent_Identity=41.6058394160584, Blast_Score=311, Evalue=9e-85,
Organism=Escherichia coli, GI1789294, Length=396, Percent_Identity=41.1616161616162, Blast_Score=292, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17508823, Length=408, Percent_Identity=43.3823529411765, Blast_Score=331, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6319857, Length=414, Percent_Identity=41.7874396135266, Blast_Score=312, Evalue=5e-86,
Organism=Drosophila melanogaster, GI17136394, Length=415, Percent_Identity=41.4457831325301, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24581203, Length=414, Percent_Identity=40.8212560386473, Blast_Score=292, Evalue=4e-79,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 44426; Mature: 44426

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQLTNLKIENKKVLLRADLNVPLENNVITDDNRIKAILPTLQYLIEKKAKIIVLSHLG
CCCCCCCEEECCCEEEEEECCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCEEEEHHHH
RIKEESQKAHFSLKSVADKLSFYLKQKVVFVPATKGRLVEDAINKLIPGEVMMLENTRFE
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCH
DLDNKAESKNNPQLGQYWASLGDVFVNDAFGTCHRTHASNVGIANNIKEKCFGFLVEKEI
HCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
NFIQKIISNPQRPLIAILGGSKVSDKIELIKNMLKKVDFLLIGGGMSYTFLKTQGFEVGT
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCEEEEEEECCCHHHH
SLLEADKIPLVKDLLSSPEAKKIILPKDFVCGKEFSPNTESAIYKCFNIPNNFMGMDIGP
HHHHHCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCH
ETIQLFKHYLTKAKTIVWNGPVGVFEFEKFSHGTKSIAQIISSLLSSTTTIIGGGDSAAA
HHHHHHHHHHHHCCEEEECCCCCCEEEHHHCCCHHHHHHHHHHHHHCCEEEEECCCCHHH
VFKFGLEKHFSHISTGGGAFLEFLEGKPMPGLACIQDIKES
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKNQLTNLKIENKKVLLRADLNVPLENNVITDDNRIKAILPTLQYLIEKKAKIIVLSHLG
CCCCCCCEEECCCEEEEEECCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCEEEEHHHH
RIKEESQKAHFSLKSVADKLSFYLKQKVVFVPATKGRLVEDAINKLIPGEVMMLENTRFE
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCH
DLDNKAESKNNPQLGQYWASLGDVFVNDAFGTCHRTHASNVGIANNIKEKCFGFLVEKEI
HCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
NFIQKIISNPQRPLIAILGGSKVSDKIELIKNMLKKVDFLLIGGGMSYTFLKTQGFEVGT
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCEEEEEEECCCHHHH
SLLEADKIPLVKDLLSSPEAKKIILPKDFVCGKEFSPNTESAIYKCFNIPNNFMGMDIGP
HHHHHCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCH
ETIQLFKHYLTKAKTIVWNGPVGVFEFEKFSHGTKSIAQIISSLLSSTTTIIGGGDSAAA
HHHHHHHHHHHHCCEEEECCCCCCEEEHHHCCCHHHHHHHHHHHHHCCEEEEECCCCHHH
VFKFGLEKHFSHISTGGGAFLEFLEGKPMPGLACIQDIKES
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA