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The map label for this gene is gapA [H]

Identifier: 197294555

GI number: 197294555

Start: 503501

End: 504508

Strand: Reverse

Name: gapA [H]

Synonym: PAa_0510

Alternate gene names: 197294555

Gene position: 504508-503501 (Counterclockwise)

Preceding gene: 197294556

Following gene: 197294554

Centisome position: 57.33

GC content: 32.44

Gene sequence:

>1008_bases
ATGAAAGTTAGAGTAGCAATTAATGGTTTTGGCCGCATCGGAAAATTAGCATTCCGTCTTATTTTTGGAAATCCTAAATT
TCAAGTAGTAGCAATTAATGATTTATCATCTTTAGAAACTATTTCTTATTTGCTTAAATATGATAGTATACAAAGACCTT
ATGAAGTTGATGCTGTTAGTTTTGAAGGAAAAAATTTAATAGTTAAAGGTGAACAAATTCCTGTTTTTCAAGAAAAAAAC
CCCCAAGATTTGCCTTGGAAAGAATTAGGGGTTGATATTGTTTTGGAATGTACAGGTTTTTTCACCGATAAAGAAAAGGC
ATCCTTACATTTAAAAGCAGGCGCTCGCAAAGTTTTAATTAGTGCTCCTGCGACAGGAGATGTTAAAACTATTGTTTATA
ACGTTAACGATCATACTTTAAATGAAAATGATATTATTGTTAGTGGAGCATCATGTACTACTAACTGTTTAGCGCCAATT
GTCAAAATTTTAAATGATAATTTCGGTATTAAACAAGCTTTTATGACCACTGTTCATAGTTATACAAGTGATCAAAGTTT
AATAGACCAAAATCACCCTAAAGGTATTTGGACTCGTCGCGGAAGAGCAGCAGCCTTTAATATGGTTCCAAGCTCAACCG
GAGCTGCCAGAGCTATTGGTTTAGTTCTTCCTGAATTAAAAGGGAAATTAGATGGAACAGCAGTAAGAGTTCCTACTATT
ACCGGTTCTTTGGTTGATTTAACAGCTGAATTAAATCAAGAAGTATCAGAAACAGAAATTAATGAAGCTTTTCAAAAAGG
CGCTAACGAAACATTAGCTTATGTGACAGATCCAATTGTATCATCAGATGTTATAGGGACTACCTATGGTTCTTTATATG
ATTCAAATACTTTGCAAATATTAAAAGAAAACCCAAGATTTATTAAATTAATGTCTTGGTACGACAATGAAATGAGTTAT
GTTAATCAGTTAGTGAGATTACTGCATAAAATAGCAAGTTTAAATTAG

Upstream 100 bases:

>100_bases
CATGCCAGGACTTGCATGCATTCAAGACATCAAAGAATCATAATTTTTTATCAAAAAAAATAATTAAATAAAAAAATAAA
AAAAAGAGGTTTTAATAATT

Downstream 100 bases:

>100_bases
TTTATTTTAAAGGACCATTTATAAAATGGTCTTTTTATTTTAAAATTTAGCATTTATTAAAAAAAAATAATAATAAAGAA
TAACTTCTTGTTTTATTTAA

Product: Glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKVRVAINGFGRIGKLAFRLIFGNPKFQVVAINDLSSLETISYLLKYDSIQRPYEVDAVSFEGKNLIVKGEQIPVFQEKN
PQDLPWKELGVDIVLECTGFFTDKEKASLHLKAGARKVLISAPATGDVKTIVYNVNDHTLNENDIIVSGASCTTNCLAPI
VKILNDNFGIKQAFMTTVHSYTSDQSLIDQNHPKGIWTRRGRAAAFNMVPSSTGAARAIGLVLPELKGKLDGTAVRVPTI
TGSLVDLTAELNQEVSETEINEAFQKGANETLAYVTDPIVSSDVIGTTYGSLYDSNTLQILKENPRFIKLMSWYDNEMSY
VNQLVRLLHKIASLN

Sequences:

>Translated_335_residues
MKVRVAINGFGRIGKLAFRLIFGNPKFQVVAINDLSSLETISYLLKYDSIQRPYEVDAVSFEGKNLIVKGEQIPVFQEKN
PQDLPWKELGVDIVLECTGFFTDKEKASLHLKAGARKVLISAPATGDVKTIVYNVNDHTLNENDIIVSGASCTTNCLAPI
VKILNDNFGIKQAFMTTVHSYTSDQSLIDQNHPKGIWTRRGRAAAFNMVPSSTGAARAIGLVLPELKGKLDGTAVRVPTI
TGSLVDLTAELNQEVSETEINEAFQKGANETLAYVTDPIVSSDVIGTTYGSLYDSNTLQILKENPRFIKLMSWYDNEMSY
VNQLVRLLHKIASLN
>Mature_335_residues
MKVRVAINGFGRIGKLAFRLIFGNPKFQVVAINDLSSLETISYLLKYDSIQRPYEVDAVSFEGKNLIVKGEQIPVFQEKN
PQDLPWKELGVDIVLECTGFFTDKEKASLHLKAGARKVLISAPATGDVKTIVYNVNDHTLNENDIIVSGASCTTNCLAPI
VKILNDNFGIKQAFMTTVHSYTSDQSLIDQNHPKGIWTRRGRAAAFNMVPSSTGAARAIGLVLPELKGKLDGTAVRVPTI
TGSLVDLTAELNQEVSETEINEAFQKGANETLAYVTDPIVSSDVIGTTYGSLYDSNTLQILKENPRFIKLMSWYDNEMSY
VNQLVRLLHKIASLN

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=337, Percent_Identity=42.7299703264095, Blast_Score=268, Evalue=4e-72,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=44.1791044776119, Blast_Score=261, Evalue=5e-70,
Organism=Escherichia coli, GI1788079, Length=336, Percent_Identity=43.75, Blast_Score=270, Evalue=9e-74,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=38.1381381381381, Blast_Score=234, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17534677, Length=343, Percent_Identity=44.8979591836735, Blast_Score=276, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI17534679, Length=343, Percent_Identity=44.6064139941691, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI32566163, Length=343, Percent_Identity=44.8979591836735, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17568413, Length=343, Percent_Identity=44.8979591836735, Blast_Score=272, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=45.0746268656716, Blast_Score=289, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=45.3731343283582, Blast_Score=287, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=44.1791044776119, Blast_Score=285, Evalue=5e-78,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=43.2835820895522, Blast_Score=262, Evalue=2e-70,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=43.2835820895522, Blast_Score=262, Evalue=2e-70,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=42.6865671641791, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=42.6865671641791, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI19922412, Length=329, Percent_Identity=40.4255319148936, Blast_Score=248, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36915; Mature: 36915

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRVAINGFGRIGKLAFRLIFGNPKFQVVAINDLSSLETISYLLKYDSIQRPYEVDAVS
CEEEEEECCCCHHCEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEE
FEGKNLIVKGEQIPVFQEKNPQDLPWKELGVDIVLECTGFFTDKEKASLHLKAGARKVLI
ECCCEEEEECCCCCEECCCCCCCCCHHHCCEEEEEEEECCCCCCCCCEEEEECCCEEEEE
SAPATGDVKTIVYNVNDHTLNENDIIVSGASCTTNCLAPIVKILNDNFGIKQAFMTTVHS
ECCCCCCEEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
YTSDQSLIDQNHPKGIWTRRGRAAAFNMVPSSTGAARAIGLVLPELKGKLDGTAVRVPTI
CCCCCHHHHCCCCCCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEC
TGSLVDLTAELNQEVSETEINEAFQKGANETLAYVTDPIVSSDVIGTTYGSLYDSNTLQI
CCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEE
LKENPRFIKLMSWYDNEMSYVNQLVRLLHKIASLN
EECCCCEEEEEEHHCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVRVAINGFGRIGKLAFRLIFGNPKFQVVAINDLSSLETISYLLKYDSIQRPYEVDAVS
CEEEEEECCCCHHCEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEE
FEGKNLIVKGEQIPVFQEKNPQDLPWKELGVDIVLECTGFFTDKEKASLHLKAGARKVLI
ECCCEEEEECCCCCEECCCCCCCCCHHHCCEEEEEEEECCCCCCCCCEEEEECCCEEEEE
SAPATGDVKTIVYNVNDHTLNENDIIVSGASCTTNCLAPIVKILNDNFGIKQAFMTTVHS
ECCCCCCEEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
YTSDQSLIDQNHPKGIWTRRGRAAAFNMVPSSTGAARAIGLVLPELKGKLDGTAVRVPTI
CCCCCHHHHCCCCCCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEC
TGSLVDLTAELNQEVSETEINEAFQKGANETLAYVTDPIVSSDVIGTTYGSLYDSNTLQI
CCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEE
LKENPRFIKLMSWYDNEMSYVNQLVRLLHKIASLN
EECCCCEEEEEEHHCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10463150; 11466286 [H]