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The map label for this gene is himA [H]

Identifier: 197294469

GI number: 197294469

Start: 403547

End: 403834

Strand: Reverse

Name: himA [H]

Synonym: PAa_0397

Alternate gene names: 197294469

Gene position: 403834-403547 (Counterclockwise)

Preceding gene: 197294470

Following gene: 197294468

Centisome position: 45.89

GC content: 35.42

Gene sequence:

>288_bases
ATGACAAAAAAAGAATTAATCAGAGCTATTGCAAAACGTCAAAACATTTCTATCGTTCAAACAGAAGAATTTTACAATGC
ATTTGAACAAGTTTTATTCGAAGCTATAGCTGCTAACGACGAAGTAATTTTATCACCTTCAATTGGAACATTCGCTTTAA
GACACAGGCAAGCACGTTTAGGACGCAATCCACAAACAGGCGAACAAATTGAAATACCTGAAAAAACCGCAGTCGTTTTT
AGACCTTCACGAACAATCAAAGAAGAAGTACGCGACATCGAATTATAA

Upstream 100 bases:

>100_bases
CCAACAACAAAATAACAACACAACGCCTCGGCAACAAACAACCAACAAATCATACAAAGAAAGGAGGAAACACAATATGG
CACAAAGAGAATTAATGAGA

Downstream 100 bases:

>100_bases
TAAAATAACCTTATCTTAAACATTGAGGCGGCGTCTCTTACACTCCCAAAAGATATATCATATTGCAGTGCAGACGCTGC
CTCAATAAAAAAACCTATCA

Product: nucleoid DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 95; Mature: 94

Protein sequence:

>95_residues
MTKKELIRAIAKRQNISIVQTEEFYNAFEQVLFEAIAANDEVILSPSIGTFALRHRQARLGRNPQTGEQIEIPEKTAVVF
RPSRTIKEEVRDIEL

Sequences:

>Translated_95_residues
MTKKELIRAIAKRQNISIVQTEEFYNAFEQVLFEAIAANDEVILSPSIGTFALRHRQARLGRNPQTGEQIEIPEKTAVVF
RPSRTIKEEVRDIEL
>Mature_94_residues
TKKELIRAIAKRQNISIVQTEEFYNAFEQVLFEAIAANDEVILSPSIGTFALRHRQARLGRNPQTGEQIEIPEKTAVVFR
PSRTIKEEVRDIEL

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

None

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10910; Mature: 10778

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKELIRAIAKRQNISIVQTEEFYNAFEQVLFEAIAANDEVILSPSIGTFALRHRQARL
CCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHC
GRNPQTGEQIEIPEKTAVVFRPSRTIKEEVRDIEL
CCCCCCCCEEECCCCEEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure 
TKKELIRAIAKRQNISIVQTEEFYNAFEQVLFEAIAANDEVILSPSIGTFALRHRQARL
CHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHC
GRNPQTGEQIEIPEKTAVVFRPSRTIKEEVRDIEL
CCCCCCCCEEECCCCEEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]