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The map label for this gene is dnaC [H]

Identifier: 197294447

GI number: 197294447

Start: 382811

End: 384094

Strand: Direct

Name: dnaC [H]

Synonym: PAa_0371

Alternate gene names: 197294447

Gene position: 382811-384094 (Clockwise)

Preceding gene: 197294426

Following gene: 197294448

Centisome position: 43.5

GC content: 29.6

Gene sequence:

>1284_bases
ATGATTGAAGCTGAACGTGCATTATTAGGAACACTATTGTTAAATCCAGAAAAAATGGATGCTGTTATAAATTTAGTTAA
CACAAACAATTTTTCCAACCCCAAGCATCGTTGTATCTTTGAGACAATGAAGCAATTAAAACTGCAAAACCGCGAAATTA
ATTATGTTACGGTTGGTTCTGTTTTAGATAACAATTTATACAAAATAGGAGGAATTGATTATTTAATTGAATTAGTGGAG
ATGGCTCCTGCAAGTGAATATTTAGAGACATATATTGATTTAATTAAAGAAAATACCCTTAAAAGAGATTTGTTAGGATT
AATTAAGCAATTACCAACCGCATTATCAAAAAGTAAAAATATCCATAATTATTTGCAAACAGTCAAAAACCAAGTAGAAG
GTTTTATGCAAAAAACCAAATCTCCTTTTATTTCTACAAAAACATTAATTCCTTATATTCGCCAAAGTATAGTTAATGAT
GAAAAAGACAACCAACTTGTAGGAATAAAAACAGGCTTTAAAAATCTAGATGAATTAATTTCTGGTTTCAAACCTAACCA
ATTAATTATCTTAGGTGCAAGAACTGGAATGGGGAAAACTGCTTTTATGTTAAATTTGGCTTGTAATATTGCAAAAAACT
TTACTACCAACCCCGAAAACCAAAAAGCAGTTATTTTTAGTTTAGAAATGGCAGCGGAAGAATTAGGAATTAGGTTACTT
TCTTCTGCTTCTCAAATCCCTTTAAAACAACTCCAACACAAAAACTTAACTAAAAATGACAAATTACAATTACTTATCGC
TGATGACAAAATTACGCAATTAAACATTTTAATTGATGATGATAGAAATAACAAAATTGGAGATATTAAAACCAAATGCC
GTCAAATGAAATATACTAAGGGACTTGATATTGTCTTTATTGATTACCTCCATTTATTAAAAGACGACCAAAGTTTTAAT
ACATATCAAGCAATATCTGTGATTTCACGCGAATTAAAAAAACTAGCAAGTGAACTTAATATTCCAATTGTGGCTTTAAG
TCAAATGAACCGTGCAACTTATGTAAGAGAAGTTAAAAGCCCACAATTAACAGATTTAAGAGATTCAGGAACAATCGAAC
AAGACGCTGATGTTGTGATGTTATTACATCGTGAAAGTTATTATCAAAAACCTGATATTGACCCACATACGAATTTAATT
ATTGCTAAAAACCGTAGCGGTCAATTAGGTGAATGTAGTTTTAATTTTTATAAACAAATCCAAAGATTTGAAGCAAAAGA
ATAA

Upstream 100 bases:

>100_bases
GTACTGGTTGAGAACAACAAATTTATCCAAATTGTTTATTAATTAAAAATAAACAGTTTGGATTTTTTTGTATCCAAACT
GAGAAAAAGGAGTTTGAAAG

Downstream 100 bases:

>100_bases
GAATAAAAAAGGAAATAAAAATATGAAACAAATATCTAATTTAGATTTTAATAATATTAACGTTTTTAATCATAAATCTT
TGTGCGTTAACATCACCAAA

Product: Replicative DNA helicase, prophage

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MIEAERALLGTLLLNPEKMDAVINLVNTNNFSNPKHRCIFETMKQLKLQNREINYVTVGSVLDNNLYKIGGIDYLIELVE
MAPASEYLETYIDLIKENTLKRDLLGLIKQLPTALSKSKNIHNYLQTVKNQVEGFMQKTKSPFISTKTLIPYIRQSIVND
EKDNQLVGIKTGFKNLDELISGFKPNQLIILGARTGMGKTAFMLNLACNIAKNFTTNPENQKAVIFSLEMAAEELGIRLL
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIGDIKTKCRQMKYTKGLDIVFIDYLHLLKDDQSFN
TYQAISVISRELKKLASELNIPIVALSQMNRATYVREVKSPQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLI
IAKNRSGQLGECSFNFYKQIQRFEAKE

Sequences:

>Translated_427_residues
MIEAERALLGTLLLNPEKMDAVINLVNTNNFSNPKHRCIFETMKQLKLQNREINYVTVGSVLDNNLYKIGGIDYLIELVE
MAPASEYLETYIDLIKENTLKRDLLGLIKQLPTALSKSKNIHNYLQTVKNQVEGFMQKTKSPFISTKTLIPYIRQSIVND
EKDNQLVGIKTGFKNLDELISGFKPNQLIILGARTGMGKTAFMLNLACNIAKNFTTNPENQKAVIFSLEMAAEELGIRLL
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIGDIKTKCRQMKYTKGLDIVFIDYLHLLKDDQSFN
TYQAISVISRELKKLASELNIPIVALSQMNRATYVREVKSPQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLI
IAKNRSGQLGECSFNFYKQIQRFEAKE
>Mature_427_residues
MIEAERALLGTLLLNPEKMDAVINLVNTNNFSNPKHRCIFETMKQLKLQNREINYVTVGSVLDNNLYKIGGIDYLIELVE
MAPASEYLETYIDLIKENTLKRDLLGLIKQLPTALSKSKNIHNYLQTVKNQVEGFMQKTKSPFISTKTLIPYIRQSIVND
EKDNQLVGIKTGFKNLDELISGFKPNQLIILGARTGMGKTAFMLNLACNIAKNFTTNPENQKAVIFSLEMAAEELGIRLL
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIGDIKTKCRQMKYTKGLDIVFIDYLHLLKDDQSFN
TYQAISVISRELKKLASELNIPIVALSQMNRATYVREVKSPQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLI
IAKNRSGQLGECSFNFYKQIQRFEAKE

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=436, Percent_Identity=30.7339449541284, Blast_Score=211, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 48646; Mature: 48646

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEAERALLGTLLLNPEKMDAVINLVNTNNFSNPKHRCIFETMKQLKLQNREINYVTVGS
CCCHHHHHHHHHHCCHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECC
VLDNNLYKIGGIDYLIELVEMAPASEYLETYIDLIKENTLKRDLLGLIKQLPTALSKSKN
HHCCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IHNYLQTVKNQVEGFMQKTKSPFISTKTLIPYIRQSIVNDEKDNQLVGIKTGFKNLDELI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHH
SGFKPNQLIILGARTGMGKTAFMLNLACNIAKNFTTNPENQKAVIFSLEMAAEELGIRLL
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHH
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIGDIKTKCRQMKYTK
HCCCCCCHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
GLDIVFIDYLHLLKDDQSFNTYQAISVISRELKKLASELNIPIVALSQMNRATYVREVKS
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHCHHHHHHHHHCC
PQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLIIAKNRSGQLGECSFNFYKQI
CCCCCCCCCCCCCCCCCEEEEEECHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
QRFEAKE
HHHHCCC
>Mature Secondary Structure
MIEAERALLGTLLLNPEKMDAVINLVNTNNFSNPKHRCIFETMKQLKLQNREINYVTVGS
CCCHHHHHHHHHHCCHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECC
VLDNNLYKIGGIDYLIELVEMAPASEYLETYIDLIKENTLKRDLLGLIKQLPTALSKSKN
HHCCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IHNYLQTVKNQVEGFMQKTKSPFISTKTLIPYIRQSIVNDEKDNQLVGIKTGFKNLDELI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHH
SGFKPNQLIILGARTGMGKTAFMLNLACNIAKNFTTNPENQKAVIFSLEMAAEELGIRLL
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHH
SSASQIPLKQLQHKNLTKNDKLQLLIADDKITQLNILIDDDRNNKIGDIKTKCRQMKYTK
HCCCCCCHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
GLDIVFIDYLHLLKDDQSFNTYQAISVISRELKKLASELNIPIVALSQMNRATYVREVKS
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHCHHHHHHHHHCC
PQLTDLRDSGTIEQDADVVMLLHRESYYQKPDIDPHTNLIIAKNRSGQLGECSFNFYKQI
CCCCCCCCCCCCCCCCCEEEEEECHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
QRFEAKE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]