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The map label for this gene is engC

Identifier: 197294430

GI number: 197294430

Start: 363311

End: 364243

Strand: Reverse

Name: engC

Synonym: PAa_0348

Alternate gene names: 197294430

Gene position: 364243-363311 (Counterclockwise)

Preceding gene: 197294431

Following gene: 197294429

Centisome position: 41.39

GC content: 26.26

Gene sequence:

>933_bases
TTGAAAAAAGCCTTAGTTATCAGATTTTTAGCAGGTATTTATTATATTCAAGATCTTGACAATCAAACTATTTTAAAAGC
TCAAAAAAAAGGGGTTTTAAAAAAATCTAATTTCATACAGGATAATCAATTAAAAAATAATCGTGATAAAATGAGCATTA
AAGTAGGGGATATTGTTCTTTATGGAATGTGTTATGATAAATATTTAATTTATGCTATTTTGCCCCGTAAAAATGAATTA
AAAAGACCTAATATTGCAAACATTGACCAAGTATTATTGGTTTTTTCTTTGGTAAAACCCCATTTCCAAACACTTCTTTT
AGATAAATTTTTGTTAATTTTACAACAACATAAATTAGATGTCATCTTAGTTTTTTCTAAAATAGATTTAATAGAAAAAG
AAGAATTAGAAGAAATTCAACAAAACATGAATTATTACTTTCCTTTTTACACTTGTTATTATGTTGATTCCAAACAACAA
ATAGGGATTGGTGTTTTAAAAAATATTTTTGAACAAAAAATCACTGTTTTAGCTGGACAAACGGGAGTTGGCAAGTCAAC
TTTACTAAAAGCTTTGATTCCTGATGCAAATTTAAAAACCCAAGAAATTTCTGAAAGTTTAGGTAGAGGAAAACACACTA
CCAAAAATGCTCAATTATATCTTTTCAACAACGGGTTTATCGCTGATACTCCTGGTTTTTCTAAATTAGATTTAGGTGGC
TTTTCTTATCAAAATTTAAAAAATTTTTATCCTGATTTTTTAAAATATGTTGATAATTGTTATTTTGGCACAAATTGCCT
TCATTTGCAAGAAACCCAATGTGGCGTTAAAGAGGCTTTGACACAAGGAAAAATTATTCCTTCGCGATATTCTAATTATT
GTTATTTCATGGAAGAAATTAAAAAAGAGAAAAAAATATATGTTAAAAATTAA

Upstream 100 bases:

>100_bases
AAAATGTTTATATGTTATAATAATAATAATTAGTGATTTTTAAAAATGCAAAAATAATCTGTTAAAAGATTTTAATAGAA
ATAGAAATAGAGGATGTAGT

Downstream 100 bases:

>100_bases
TATAATTTAACATCAACAACTTAAAAGACGATAGTTTTGATAATTTATATTAAATACATGTTTTTGTTTTCCTTATTTAA
TTTATTAGTTTTCAAATTTT

Product: GTPase EngC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKKALVIRFLAGIYYIQDLDNQTILKAQKKGVLKKSNFIQDNQLKNNRDKMSIKVGDIVLYGMCYDKYLIYAILPRKNEL
KRPNIANIDQVLLVFSLVKPHFQTLLLDKFLLILQQHKLDVILVFSKIDLIEKEELEEIQQNMNYYFPFYTCYYVDSKQQ
IGIGVLKNIFEQKITVLAGQTGVGKSTLLKALIPDANLKTQEISESLGRGKHTTKNAQLYLFNNGFIADTPGFSKLDLGG
FSYQNLKNFYPDFLKYVDNCYFGTNCLHLQETQCGVKEALTQGKIIPSRYSNYCYFMEEIKKEKKIYVKN

Sequences:

>Translated_310_residues
MKKALVIRFLAGIYYIQDLDNQTILKAQKKGVLKKSNFIQDNQLKNNRDKMSIKVGDIVLYGMCYDKYLIYAILPRKNEL
KRPNIANIDQVLLVFSLVKPHFQTLLLDKFLLILQQHKLDVILVFSKIDLIEKEELEEIQQNMNYYFPFYTCYYVDSKQQ
IGIGVLKNIFEQKITVLAGQTGVGKSTLLKALIPDANLKTQEISESLGRGKHTTKNAQLYLFNNGFIADTPGFSKLDLGG
FSYQNLKNFYPDFLKYVDNCYFGTNCLHLQETQCGVKEALTQGKIIPSRYSNYCYFMEEIKKEKKIYVKN
>Mature_310_residues
MKKALVIRFLAGIYYIQDLDNQTILKAQKKGVLKKSNFIQDNQLKNNRDKMSIKVGDIVLYGMCYDKYLIYAILPRKNEL
KRPNIANIDQVLLVFSLVKPHFQTLLLDKFLLILQQHKLDVILVFSKIDLIEKEELEEIQQNMNYYFPFYTCYYVDSKQQ
IGIGVLKNIFEQKITVLAGQTGVGKSTLLKALIPDANLKTQEISESLGRGKHTTKNAQLYLFNNGFIADTPGFSKLDLGG
FSYQNLKNFYPDFLKYVDNCYFGTNCLHLQETQCGVKEALTQGKIIPSRYSNYCYFMEEIKKEKKIYVKN

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=249, Percent_Identity=30.9236947791165, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA_PHYAS (B1V9R1)

Other databases:

- EMBL:   AM422018
- RefSeq:   YP_001798971.1
- ProteinModelPortal:   B1V9R1
- SMR:   B1V9R1
- GeneID:   6799024
- GenomeReviews:   AM422018_GR
- HOGENOM:   HBG652450
- OMA:   TRARGVF
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR016027
- InterPro:   IPR004881
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 35894; Mature: 35894

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALVIRFLAGIYYIQDLDNQTILKAQKKGVLKKSNFIQDNQLKNNRDKMSIKVGDIVL
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCEEEEEECCEEE
YGMCYDKYLIYAILPRKNELKRPNIANIDQVLLVFSLVKPHFQTLLLDKFLLILQQHKLD
EEHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VILVFSKIDLIEKEELEEIQQNMNYYFPFYTCYYVDSKQQIGIGVLKNIFEQKITVLAGQ
EEEEEECCCCCCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEECC
TGVGKSTLLKALIPDANLKTQEISESLGRGKHTTKNAQLYLFNNGFIADTPGFSKLDLGG
CCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCEEECCCCCCEEECCC
FSYQNLKNFYPDFLKYVDNCYFGTNCLHLQETQCGVKEALTQGKIIPSRYSNYCYFMEEI
CCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHCCHHHHHHCCCCCHHHHCCHHHHHHHH
KKEKKIYVKN
HHCCCEEECC
>Mature Secondary Structure
MKKALVIRFLAGIYYIQDLDNQTILKAQKKGVLKKSNFIQDNQLKNNRDKMSIKVGDIVL
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCEEEEEECCEEE
YGMCYDKYLIYAILPRKNELKRPNIANIDQVLLVFSLVKPHFQTLLLDKFLLILQQHKLD
EEHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VILVFSKIDLIEKEELEEIQQNMNYYFPFYTCYYVDSKQQIGIGVLKNIFEQKITVLAGQ
EEEEEECCCCCCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEECC
TGVGKSTLLKALIPDANLKTQEISESLGRGKHTTKNAQLYLFNNGFIADTPGFSKLDLGG
CCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCEEECCCCCCEEECCC
FSYQNLKNFYPDFLKYVDNCYFGTNCLHLQETQCGVKEALTQGKIIPSRYSNYCYFMEEI
CCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHCCHHHHHHCCCCCHHHHCCHHHHHHHH
KKEKKIYVKN
HHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA