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The map label for this gene is zntA [H]

Identifier: 197294381

GI number: 197294381

Start: 299187

End: 301103

Strand: Reverse

Name: zntA [H]

Synonym: PAa_0270

Alternate gene names: 197294381

Gene position: 301103-299187 (Counterclockwise)

Preceding gene: 197294382

Following gene: 197294379

Centisome position: 34.22

GC content: 28.9

Gene sequence:

>1917_bases
TTGAATGTCAATAACGAAAAAACAAATCAAAAACCCTTAATTTGTTTTTTTATAGGTATCTTTTTATATTTAATTTTTTT
CCTTTGGCAACGTTTTAATTTTTCAACCCTACAACCTTTTTCTTTACCATTTGCACTTATTATTTTATTTTTGTTAGGTT
ATAGTGTTATTTCAGAAGGTTTTATAGATACTTGCAAAGAATCTAAAGCAAATAAAAAATTTACTCCTAATATCGACATT
TTAATGTCTTTAGCAGCTTTAGGTTCTTTATTTTTAGCGAATCATAGTGAAGCTATTTTATTAATTTTAATTTTTTCTGG
AGCATCTTTTTTAGAACAATACGTAGAAAACAAAAGTCAGAAAGAAATAAAAAACCTTTTAAAATTACACCCTTCAGAAG
CACGCTTATTGCAAAAAGACGGCAGTACGCAAATTATTTCTTCTCAACATTTAAAAACTCAAGATTTACTTTTAATTTTG
GAAGGCGATGCAATTCCTACAGATGGCGTGATTATTTCTGGTTATCCTTGTGTTGATGAATCTAATATTACAGGTGAGTC
TATTCCTTGCGAAAAACAACCTGGGGATTTAGTTTATGGAAGCACTATTAATGTTAATAATACTTTCGTGATGCGTGTGA
CAACTACTAACGAAAAAACTGTTTTTGCTCAAATTGTGAAATTAGTTTCTCAAACCAAAAATAGTTTTTCTAAAACAGCT
ACTTTAATCAAAAAAATAGAACCTGTTTATGTCAAGACTATTATGTTTATAGTGATTTTTGTTTTAACTATAGGGGGAAT
TATTAATTTCCTTGATGCAAGTAAGCTGGATTTTGGAAAATTATTTTCTAAAACGATGGTTTTTTTAACAGTTTCTTCCC
CTTGTGCTTTAGCTGCTTCTGATATTCCTTCCACTTTGGCAGCAATCACTAATTTAGCTAAAAAAGGAGTTTTATTCAAA
AACGTTAAATCTTTAGAGATTATGGCAGAAACCAAAGCTTTTGCATGTGATAAAACAGGGACTTTAACCGAAGGAAAACC
AGAAGTTACGGATCTTTATGTAGACCCTCATATTTCTGAAGAAAAATACCATCATTATTTAGAAATATTATTAGCCATGG
AACAAAAATCTAACCATCCTTTGGCTGCAGCGATTAAAAATTATTTTAATATCCGCTCTCATTTAATGTTAGAAATCACT
AATTTAGTGGGCGTTGGAATAGAAGCTTTTTATCAAAATGATTATTATCTTATTTCTAAAGCAATTGCCTTTCCTAAAGT
ATCTAAAGATTTGGAAATAAAAACAGAAAAATTTTTATCACAAGGAAAAACAGTTATTTATTTTAGTAGTAATAATCGCG
TTCTTATTGCTTTGGCATTTTTAGATAAAGTAAGACTTCCAGCAACGAAATTGATAGATTATTTTAATAAGAAAAATATT
AATACAGCAGTTATTTCAGGCGATAACGAACAAAGCGTTCTTTTTTTAAAAGAAGAATTGAATTTAAAGCAAGCTTGGGG
TAATAATTTACCTATACAAAAAGTAAAAAAAATTCAGCAATTACAAAACAAATACGGAATAACAGTTATGGTAGGAGATG
GCGTTAATGATGCTCCTGCTTTAAGAGTTGCTGATGTTGGTATTGCAATGCAAAATGGCACAGATGTTTCTATTGATGTT
GCAGATGCTGTTTTAATGAAAAATGACTTATCTAAAATTATTTATACCCATAAAGTAGCTCTTAAATTAAATAAAATTAT
TCGACAAAATATTTTTTTTGCTATGAGTGTTGTTGTCGTTCTTAATTTAATAAACATGATAACTCAAATCCCTTTACCTT
TGGCTGTTTTTTGCCACGAAGGAAGTACTTTATTAGTCATTTTGAATGCTTTAAGACTTTTAAAAAGCGAAAAATAG

Upstream 100 bases:

>100_bases
GTTGAAGACAAACCAGAACAAGAGAATTAATTTTTTTTGATTAAAATTCTTATGAAAAAACAATAAAATTATAAATAATT
AATTGAAAGGTGTTATAAAT

Downstream 100 bases:

>100_bases
ATATTTAAAAGAAAAAAAGAGACCTTAAAAAGTCTCTTTTTGTTTTAGTTGTTGTAGTTGGCGAATCTTTTTTTAACTTT
TGGCATATAAATATATAAAA

Product: Cation transport ATPase

Products: NA

Alternate protein names: Zn(2+)-translocating P-type ATPase [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MNVNNEKTNQKPLICFFIGIFLYLIFFLWQRFNFSTLQPFSLPFALIILFLLGYSVISEGFIDTCKESKANKKFTPNIDI
LMSLAALGSLFLANHSEAILLILIFSGASFLEQYVENKSQKEIKNLLKLHPSEARLLQKDGSTQIISSQHLKTQDLLLIL
EGDAIPTDGVIISGYPCVDESNITGESIPCEKQPGDLVYGSTINVNNTFVMRVTTTNEKTVFAQIVKLVSQTKNSFSKTA
TLIKKIEPVYVKTIMFIVIFVLTIGGIINFLDASKLDFGKLFSKTMVFLTVSSPCALAASDIPSTLAAITNLAKKGVLFK
NVKSLEIMAETKAFACDKTGTLTEGKPEVTDLYVDPHISEEKYHHYLEILLAMEQKSNHPLAAAIKNYFNIRSHLMLEIT
NLVGVGIEAFYQNDYYLISKAIAFPKVSKDLEIKTEKFLSQGKTVIYFSSNNRVLIALAFLDKVRLPATKLIDYFNKKNI
NTAVISGDNEQSVLFLKEELNLKQAWGNNLPIQKVKKIQQLQNKYGITVMVGDGVNDAPALRVADVGIAMQNGTDVSIDV
ADAVLMKNDLSKIIYTHKVALKLNKIIRQNIFFAMSVVVVLNLINMITQIPLPLAVFCHEGSTLLVILNALRLLKSEK

Sequences:

>Translated_638_residues
MNVNNEKTNQKPLICFFIGIFLYLIFFLWQRFNFSTLQPFSLPFALIILFLLGYSVISEGFIDTCKESKANKKFTPNIDI
LMSLAALGSLFLANHSEAILLILIFSGASFLEQYVENKSQKEIKNLLKLHPSEARLLQKDGSTQIISSQHLKTQDLLLIL
EGDAIPTDGVIISGYPCVDESNITGESIPCEKQPGDLVYGSTINVNNTFVMRVTTTNEKTVFAQIVKLVSQTKNSFSKTA
TLIKKIEPVYVKTIMFIVIFVLTIGGIINFLDASKLDFGKLFSKTMVFLTVSSPCALAASDIPSTLAAITNLAKKGVLFK
NVKSLEIMAETKAFACDKTGTLTEGKPEVTDLYVDPHISEEKYHHYLEILLAMEQKSNHPLAAAIKNYFNIRSHLMLEIT
NLVGVGIEAFYQNDYYLISKAIAFPKVSKDLEIKTEKFLSQGKTVIYFSSNNRVLIALAFLDKVRLPATKLIDYFNKKNI
NTAVISGDNEQSVLFLKEELNLKQAWGNNLPIQKVKKIQQLQNKYGITVMVGDGVNDAPALRVADVGIAMQNGTDVSIDV
ADAVLMKNDLSKIIYTHKVALKLNKIIRQNIFFAMSVVVVLNLINMITQIPLPLAVFCHEGSTLLVILNALRLLKSEK
>Mature_638_residues
MNVNNEKTNQKPLICFFIGIFLYLIFFLWQRFNFSTLQPFSLPFALIILFLLGYSVISEGFIDTCKESKANKKFTPNIDI
LMSLAALGSLFLANHSEAILLILIFSGASFLEQYVENKSQKEIKNLLKLHPSEARLLQKDGSTQIISSQHLKTQDLLLIL
EGDAIPTDGVIISGYPCVDESNITGESIPCEKQPGDLVYGSTINVNNTFVMRVTTTNEKTVFAQIVKLVSQTKNSFSKTA
TLIKKIEPVYVKTIMFIVIFVLTIGGIINFLDASKLDFGKLFSKTMVFLTVSSPCALAASDIPSTLAAITNLAKKGVLFK
NVKSLEIMAETKAFACDKTGTLTEGKPEVTDLYVDPHISEEKYHHYLEILLAMEQKSNHPLAAAIKNYFNIRSHLMLEIT
NLVGVGIEAFYQNDYYLISKAIAFPKVSKDLEIKTEKFLSQGKTVIYFSSNNRVLIALAFLDKVRLPATKLIDYFNKKNI
NTAVISGDNEQSVLFLKEELNLKQAWGNNLPIQKVKKIQQLQNKYGITVMVGDGVNDAPALRVADVGIAMQNGTDVSIDV
ADAVLMKNDLSKIIYTHKVALKLNKIIRQNIFFAMSVVVVLNLINMITQIPLPLAVFCHEGSTLLVILNALRLLKSEK

Specific function: Couples the hydrolysis of ATP with the transport of zinc into the cell [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=588, Percent_Identity=24.8299319727891, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI55743073, Length=552, Percent_Identity=25.5434782608696, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI115529486, Length=360, Percent_Identity=27.7777777777778, Blast_Score=136, Evalue=8e-32,
Organism=Homo sapiens, GI22748667, Length=274, Percent_Identity=27.3722627737226, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI51944966, Length=285, Percent_Identity=27.3684210526316, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI83700225, Length=273, Percent_Identity=27.8388278388278, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4502271, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI237681111, Length=279, Percent_Identity=26.5232974910394, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI21361181, Length=279, Percent_Identity=26.5232974910394, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI237681109, Length=279, Percent_Identity=26.5232974910394, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI153946397, Length=262, Percent_Identity=27.4809160305344, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI297374799, Length=280, Percent_Identity=26.7857142857143, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI48762687, Length=331, Percent_Identity=25.6797583081571, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48762691, Length=331, Percent_Identity=25.6797583081571, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48762685, Length=327, Percent_Identity=25.3822629969419, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48762689, Length=327, Percent_Identity=25.3822629969419, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI118498343, Length=105, Percent_Identity=40.9523809523809, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789879, Length=637, Percent_Identity=31.2401883830455, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1786691, Length=507, Percent_Identity=28.2051282051282, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1786914, Length=537, Percent_Identity=24.0223463687151, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17556548, Length=594, Percent_Identity=26.2626262626263, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71997262, Length=643, Percent_Identity=21.7729393468118, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71997275, Length=661, Percent_Identity=21.9364599092284, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559224, Length=278, Percent_Identity=26.6187050359712, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71997269, Length=643, Percent_Identity=21.7729393468118, Blast_Score=79, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6320475, Length=560, Percent_Identity=27.8571428571429, Blast_Score=173, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6319772, Length=520, Percent_Identity=26.9230769230769, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6321430, Length=269, Percent_Identity=23.0483271375465, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321271, Length=356, Percent_Identity=26.123595505618, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325221, Length=300, Percent_Identity=24.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221329854, Length=415, Percent_Identity=27.2289156626506, Blast_Score=133, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR001366
- InterPro:   IPR006404
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.5 [H]

Molecular weight: Translated: 71021; Mature: 71021

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVNNEKTNQKPLICFFIGIFLYLIFFLWQRFNFSTLQPFSLPFALIILFLLGYSVISEG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FIDTCKESKANKKFTPNIDILMSLAALGSLFLANHSEAILLILIFSGASFLEQYVENKSQ
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCHH
KEIKNLLKLHPSEARLLQKDGSTQIISSQHLKTQDLLLILEGDAIPTDGVIISGYPCVDE
HHHHHHHHCCCCHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCC
SNITGESIPCEKQPGDLVYGSTINVNNTFVMRVTTTNEKTVFAQIVKLVSQTKNSFSKTA
CCCCCCCCCCCCCCCCEEECCEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
TLIKKIEPVYVKTIMFIVIFVLTIGGIINFLDASKLDFGKLFSKTMVFLTVSSPCALAAS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCHHHHH
DIPSTLAAITNLAKKGVLFKNVKSLEIMAETKAFACDKTGTLTEGKPEVTDLYVDPHISE
CCHHHHHHHHHHHHCCCHHHCCHHHHEEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCH
EKYHHYLEILLAMEQKSNHPLAAAIKNYFNIRSHLMLEITNLVGVGIEAFYQNDYYLISK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCEEEEEH
AIAFPKVSKDLEIKTEKFLSQGKTVIYFSSNNRVLIALAFLDKVRLPATKLIDYFNKKNI
HHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCEEEEEEEEHHHHCCCHHHHHHHHCCCCC
NTAVISGDNEQSVLFLKEELNLKQAWGNNLPIQKVKKIQQLQNKYGITVMVGDGVNDAPA
CEEEEECCCCCEEEEEHHHCCHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCC
LRVADVGIAMQNGTDVSIDVADAVLMKNDLSKIIYTHKVALKLNKIIRQNIFFAMSVVVV
EEEEEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLINMITQIPLPLAVFCHEGSTLLVILNALRLLKSEK
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVNNEKTNQKPLICFFIGIFLYLIFFLWQRFNFSTLQPFSLPFALIILFLLGYSVISEG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FIDTCKESKANKKFTPNIDILMSLAALGSLFLANHSEAILLILIFSGASFLEQYVENKSQ
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCHH
KEIKNLLKLHPSEARLLQKDGSTQIISSQHLKTQDLLLILEGDAIPTDGVIISGYPCVDE
HHHHHHHHCCCCHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCC
SNITGESIPCEKQPGDLVYGSTINVNNTFVMRVTTTNEKTVFAQIVKLVSQTKNSFSKTA
CCCCCCCCCCCCCCCCEEECCEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
TLIKKIEPVYVKTIMFIVIFVLTIGGIINFLDASKLDFGKLFSKTMVFLTVSSPCALAAS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCHHHHH
DIPSTLAAITNLAKKGVLFKNVKSLEIMAETKAFACDKTGTLTEGKPEVTDLYVDPHISE
CCHHHHHHHHHHHHCCCHHHCCHHHHEEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCH
EKYHHYLEILLAMEQKSNHPLAAAIKNYFNIRSHLMLEITNLVGVGIEAFYQNDYYLISK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCEEEEEH
AIAFPKVSKDLEIKTEKFLSQGKTVIYFSSNNRVLIALAFLDKVRLPATKLIDYFNKKNI
HHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCEEEEEEEEHHHHCCCHHHHHHHHCCCCC
NTAVISGDNEQSVLFLKEELNLKQAWGNNLPIQKVKKIQQLQNKYGITVMVGDGVNDAPA
CEEEEECCCCCEEEEEHHHCCHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCC
LRVADVGIAMQNGTDVSIDVADAVLMKNDLSKIIYTHKVALKLNKIIRQNIFFAMSVVVV
EEEEEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLINMITQIPLPLAVFCHEGSTLLVILNALRLLKSEK
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]