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The map label for this gene is asnC

Identifier: 197294192

GI number: 197294192

Start: 32270

End: 33643

Strand: Reverse

Name: asnC

Synonym: PAa_0026

Alternate gene names: 197294192

Gene position: 33643-32270 (Counterclockwise)

Preceding gene: 197294193

Following gene: 197294191

Centisome position: 3.82

GC content: 28.82

Gene sequence:

>1374_bases
ATGGAAATTTCTATTAAAAATATTTTTGAAAAAGCAGATTTTTATTTAGGAAAAAAAATTATTGTTAATGGTTGGATTAG
AAATTGTCGTTTTCAAAAAAAATTAATTTTTATAGAATTAAATGATGGCACTTTTTTAGAAAATTTCCAAATTGTTTATA
AAAATGTTGATTTAGAAAAAATAAAAGATATTTTGCAAATTGGCACTTCTTTGAAAGTTGAAGGTTTTTTAAAGAAAAAC
GAAAAACAAGAAAAAAATTTAGAAATTTTGGCTCAAAATATCACTTTATTAGGTTCAAGTGATTTTTCTTATCCCATTCA
ACCAAAAAAACATTCTAAATCTTTTTTAAGAACTATCCCTCATCTAAGAACAAGAACAAAACTTTTTGGAGCAGTTTTTC
GCATTAGAAGTACTGCTTTTTTCGCCTTGCATCATTTTTTTCATAAAAAAGGTTTTTTTCACATCAATACCCCCATTATC
ACTCCTAATGATGGTGAAGGAGCTGGAGAATTATTTCAACTAACTTCCCTTAATCTAGAGCGTTTATCACAAGAAAAACC
CTCAACAATAAATTATCAAAAAGATTTTTTCGGTAAAAAAGTTTTTTTAACAGTAACAGGGCAATTAGAAGCAGAAGCAA
TGGCTTTAGCTTTGAATAAAGTTTATACTTTTGGTCCTACTTTTAGAGCTGAAAAATCAAACACTCCCAGACATGCTGCT
GAGTTTTGGATGTTAGAACCAGAAATGGCTTTTTGCGATTTAAAACAAAATTTAAAAGTTGCTCAAGAAATGTTGCAAGA
AGTTGTTGTTCAATGTCTTCAAGAAAACCAAAAAGATATTGAGTTTTTAGACCAAACAGTGAGAAATGGTTTATTACAAG
AACTTAAAAACGTTGTTCAAGAAAAAGAATTTTTAGTAATCACATATCAAAAAGCAATTGAAATTTTGGCATCAAGTGGT
GTTGCTTTTGAGAATAAAGTTTTTTATGGTTCTGATTTGGCAACCGAACACGAAAAGTTTTTGACTGAAAAACATTTTCA
AAAACCAGTTTTTATAATTGATTGGCCTAAAGAAATCAAAGCATTTTATATGAAAAATAATCCTGATCAAAAAACAGTCG
CTGCCATGGATCTTTTAATTCCTCGCGTGGGAGAATTAATCGGTGGATCACAGAGAGAAGAAAATTTAGCAGTTTTAATT
GAAAAAATGCAACAAATGAAAATCCCTCAAAAAGAATTTGAATGGTATCTAGATTTACGTCGTTTTGGCAGTTGTATTCA
CTCTGGTTTTGGTTTAGGTTTTGAAAGATTATTGCTTTTTTTGACAGGTTTAGATAATATTAGAGATGTCATTGCTTTTC
CAAGAACTTATTAA

Upstream 100 bases:

>100_bases
TTTAATTTTTCATTCTTTATAATTTTTTAATTTATTATTATGTTGTTATCGCGTTGTTATGTCAAATTTATAAAAAATAA
TCAAATAAAGGATTAAAATA

Downstream 100 bases:

>100_bases
GTTTTGATTTCGTGTTTTTAATTCATTTAAAAATAACAAAAAATTTTAAAAAACTTAAGTAACTAAAAAAAACAAACACA
GGCCAATAGTGAAAAAACAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MEISIKNIFEKADFYLGKKIIVNGWIRNCRFQKKLIFIELNDGTFLENFQIVYKNVDLEKIKDILQIGTSLKVEGFLKKN
EKQEKNLEILAQNITLLGSSDFSYPIQPKKHSKSFLRTIPHLRTRTKLFGAVFRIRSTAFFALHHFFHKKGFFHINTPII
TPNDGEGAGELFQLTSLNLERLSQEKPSTINYQKDFFGKKVFLTVTGQLEAEAMALALNKVYTFGPTFRAEKSNTPRHAA
EFWMLEPEMAFCDLKQNLKVAQEMLQEVVVQCLQENQKDIEFLDQTVRNGLLQELKNVVQEKEFLVITYQKAIEILASSG
VAFENKVFYGSDLATEHEKFLTEKHFQKPVFIIDWPKEIKAFYMKNNPDQKTVAAMDLLIPRVGELIGGSQREENLAVLI
EKMQQMKIPQKEFEWYLDLRRFGSCIHSGFGLGFERLLLFLTGLDNIRDVIAFPRTY

Sequences:

>Translated_457_residues
MEISIKNIFEKADFYLGKKIIVNGWIRNCRFQKKLIFIELNDGTFLENFQIVYKNVDLEKIKDILQIGTSLKVEGFLKKN
EKQEKNLEILAQNITLLGSSDFSYPIQPKKHSKSFLRTIPHLRTRTKLFGAVFRIRSTAFFALHHFFHKKGFFHINTPII
TPNDGEGAGELFQLTSLNLERLSQEKPSTINYQKDFFGKKVFLTVTGQLEAEAMALALNKVYTFGPTFRAEKSNTPRHAA
EFWMLEPEMAFCDLKQNLKVAQEMLQEVVVQCLQENQKDIEFLDQTVRNGLLQELKNVVQEKEFLVITYQKAIEILASSG
VAFENKVFYGSDLATEHEKFLTEKHFQKPVFIIDWPKEIKAFYMKNNPDQKTVAAMDLLIPRVGELIGGSQREENLAVLI
EKMQQMKIPQKEFEWYLDLRRFGSCIHSGFGLGFERLLLFLTGLDNIRDVIAFPRTY
>Mature_457_residues
MEISIKNIFEKADFYLGKKIIVNGWIRNCRFQKKLIFIELNDGTFLENFQIVYKNVDLEKIKDILQIGTSLKVEGFLKKN
EKQEKNLEILAQNITLLGSSDFSYPIQPKKHSKSFLRTIPHLRTRTKLFGAVFRIRSTAFFALHHFFHKKGFFHINTPII
TPNDGEGAGELFQLTSLNLERLSQEKPSTINYQKDFFGKKVFLTVTGQLEAEAMALALNKVYTFGPTFRAEKSNTPRHAA
EFWMLEPEMAFCDLKQNLKVAQEMLQEVVVQCLQENQKDIEFLDQTVRNGLLQELKNVVQEKEFLVITYQKAIEILASSG
VAFENKVFYGSDLATEHEKFLTEKHFQKPVFIIDWPKEIKAFYMKNNPDQKTVAAMDLLIPRVGELIGGSQREENLAVLI
EKMQQMKIPQKEFEWYLDLRRFGSCIHSGFGLGFERLLLFLTGLDNIRDVIAFPRTY

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=444, Percent_Identity=43.4684684684685, Blast_Score=361, Evalue=1e-99,
Organism=Homo sapiens, GI4758762, Length=465, Percent_Identity=26.6666666666667, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI45439306, Length=337, Percent_Identity=29.080118694362, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1787161, Length=446, Percent_Identity=46.6367713004484, Blast_Score=423, Evalue=1e-119,
Organism=Escherichia coli, GI1789256, Length=367, Percent_Identity=22.0708446866485, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790571, Length=367, Percent_Identity=21.7983651226158, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17556372, Length=422, Percent_Identity=30.5687203791469, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71984122, Length=450, Percent_Identity=27.3333333333333, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17551876, Length=473, Percent_Identity=25.1585623678647, Blast_Score=127, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6319872, Length=483, Percent_Identity=37.4741200828157, Blast_Score=299, Evalue=6e-82,
Organism=Saccharomyces cerevisiae, GI6321807, Length=452, Percent_Identity=26.3274336283186, Blast_Score=170, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6323011, Length=437, Percent_Identity=27.4599542334096, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19922416, Length=449, Percent_Identity=36.7483296213808, Blast_Score=275, Evalue=5e-74,
Organism=Drosophila melanogaster, GI19921528, Length=458, Percent_Identity=27.292576419214, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI17136276, Length=340, Percent_Identity=27.9411764705882, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_PHYAS (B1V8X4)

Other databases:

- EMBL:   AM422018
- RefSeq:   YP_001798733.1
- ProteinModelPortal:   B1V8X4
- SMR:   B1V8X4
- GeneID:   6799221
- GenomeReviews:   AM422018_GR
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52978; Mature: 52978

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEISIKNIFEKADFYLGKKIIVNGWIRNCRFQKKLIFIELNDGTFLENFQIVYKNVDLEK
CCCCHHHHHHHHHHHHCCHHEEEHHHHCCEEEEEEEEEEECCCCEECCEEEEEECCCHHH
IKDILQIGTSLKVEGFLKKNEKQEKNLEILAQNITLLGSSDFSYPIQPKKHSKSFLRTIP
HHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHH
HLRTRTKLFGAVFRIRSTAFFALHHFFHKKGFFHINTPIITPNDGEGAGELFQLTSLNLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEECCCCCCCCCHHHHHHHCCHH
RLSQEKPSTINYQKDFFGKKVFLTVTGQLEAEAMALALNKVYTFGPTFRAEKSNTPRHAA
HHHCCCCCCCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
EFWMLEPEMAFCDLKQNLKVAQEMLQEVVVQCLQENQKDIEFLDQTVRNGLLQELKNVVQ
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
EKEFLVITYQKAIEILASSGVAFENKVFYGSDLATEHEKFLTEKHFQKPVFIIDWPKEIK
CCCEEEEEHHHHHHHHHHCCCEEECEEEECCCCCHHHHHHHHHHHCCCCEEEEECHHHHH
AFYMKNNPDQKTVAAMDLLIPRVGELIGGSQREENLAVLIEKMQQMKIPQKEFEWYLDLR
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
RFGSCIHSGFGLGFERLLLFLTGLDNIRDVIAFPRTY
HHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCCCC
>Mature Secondary Structure
MEISIKNIFEKADFYLGKKIIVNGWIRNCRFQKKLIFIELNDGTFLENFQIVYKNVDLEK
CCCCHHHHHHHHHHHHCCHHEEEHHHHCCEEEEEEEEEEECCCCEECCEEEEEECCCHHH
IKDILQIGTSLKVEGFLKKNEKQEKNLEILAQNITLLGSSDFSYPIQPKKHSKSFLRTIP
HHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHH
HLRTRTKLFGAVFRIRSTAFFALHHFFHKKGFFHINTPIITPNDGEGAGELFQLTSLNLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEECCCCCCCCCHHHHHHHCCHH
RLSQEKPSTINYQKDFFGKKVFLTVTGQLEAEAMALALNKVYTFGPTFRAEKSNTPRHAA
HHHCCCCCCCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
EFWMLEPEMAFCDLKQNLKVAQEMLQEVVVQCLQENQKDIEFLDQTVRNGLLQELKNVVQ
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
EKEFLVITYQKAIEILASSGVAFENKVFYGSDLATEHEKFLTEKHFQKPVFIIDWPKEIK
CCCEEEEEHHHHHHHHHHCCCEEECEEEECCCCCHHHHHHHHHHHCCCCEEEEECHHHHH
AFYMKNNPDQKTVAAMDLLIPRVGELIGGSQREENLAVLIEKMQQMKIPQKEFEWYLDLR
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
RFGSCIHSGFGLGFERLLLFLTGLDNIRDVIAFPRTY
HHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA