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The map label for this gene is spxA [H]

Identifier: 197294180

GI number: 197294180

Start: 15179

End: 15643

Strand: Direct

Name: spxA [H]

Synonym: PAa_0012

Alternate gene names: 197294180

Gene position: 15179-15643 (Clockwise)

Preceding gene: 197294179

Following gene: 197294181

Centisome position: 1.72

GC content: 22.8

Gene sequence:

>465_bases
ATGGTTATTTTTTATACTAGTTTTAATTGTTCATCTTGTCAAAAAGCAAAAAAATGGTTAAAACAACACAGAATTGAATT
TATAGAACGCAGTTTATTTGGTCATGATTTTCAACAAAAAGATATCGATTTAATATTAAAATATTGCCTTCATGGGTTTG
ATGATATTATTTCTAAACTTTCTAAATTCTTTAAAGAACAAAATATTGATTTTAATAATTTAAGCACAAAAGAAGTTAAG
CAGATAATTATGCAAAAAAGAAGTATTTTAAAAAGACCTATTCTCGTTGAAGGCCAAAAAATTCAAATTGGATTTAATTC
AGAAGGTATTCGCATTTTTATGCCTAAAAATTTACGTGATTTTTTAATGAAAAATGATGTTTTTTATAAAGCTAAAGATA
AATACAAAATCTTATTAAAAAAATTTTTTGAAAATAAAAATAATGACGAACCCATCTGCAAATGA

Upstream 100 bases:

>100_bases
GACCTATTTAATTACTTATTTCAATTTTTAAAGATCAATATGAATTCATTAAGTTGCTATATTTCATTTTTTTATATAAA
AAAGAGGTTTCAATAAGTAA

Downstream 100 bases:

>100_bases
TTTTACAATTGGGTGTTGCTTTTTTTAGATAACTTTTGGATTTTTTATTGTTTTTTTAAAGGTTTAAAAATAAGTTGATA
ATTACAATTTTTTTAAATTA

Product: Putative regulatory protein spx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVIFYTSFNCSSCQKAKKWLKQHRIEFIERSLFGHDFQQKDIDLILKYCLHGFDDIISKLSKFFKEQNIDFNNLSTKEVK
QIIMQKRSILKRPILVEGQKIQIGFNSEGIRIFMPKNLRDFLMKNDVFYKAKDKYKILLKKFFENKNNDEPICK

Sequences:

>Translated_154_residues
MVIFYTSFNCSSCQKAKKWLKQHRIEFIERSLFGHDFQQKDIDLILKYCLHGFDDIISKLSKFFKEQNIDFNNLSTKEVK
QIIMQKRSILKRPILVEGQKIQIGFNSEGIRIFMPKNLRDFLMKNDVFYKAKDKYKILLKKFFENKNNDEPICK
>Mature_154_residues
MVIFYTSFNCSSCQKAKKWLKQHRIEFIERSLFGHDFQQKDIDLILKYCLHGFDDIISKLSKFFKEQNIDFNNLSTKEVK
QIIMQKRSILKRPILVEGQKIQIGFNSEGIRIFMPKNLRDFLMKNDVFYKAKDKYKILLKKFFENKNNDEPICK

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: NA

Molecular weight: Translated: 18514; Mature: 18514

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIFYTSFNCSSCQKAKKWLKQHRIEFIERSLFGHDFQQKDIDLILKYCLHGFDDIISKL
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SKFFKEQNIDFNNLSTKEVKQIIMQKRSILKRPILVEGQKIQIGFNSEGIRIFMPKNLRD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCEEEEECCCHHH
FLMKNDVFYKAKDKYKILLKKFFENKNNDEPICK
HHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVIFYTSFNCSSCQKAKKWLKQHRIEFIERSLFGHDFQQKDIDLILKYCLHGFDDIISKL
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SKFFKEQNIDFNNLSTKEVKQIIMQKRSILKRPILVEGQKIQIGFNSEGIRIFMPKNLRD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCEEEEECCCHHH
FLMKNDVFYKAKDKYKILLKKFFENKNNDEPICK
HHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]