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The map label for this gene is yafC [H]

Identifier: 134302759

GI number: 134302759

Start: 1846458

End: 1847327

Strand: Direct

Name: yafC [H]

Synonym: FTW_1968

Alternate gene names: 134302759

Gene position: 1846458-1847327 (Clockwise)

Preceding gene: 134302755

Following gene: 134302761

Centisome position: 97.26

GC content: 31.49

Gene sequence:

>870_bases
ATGGATAAATTTGAATGTATGAAAAGCTTTATACTAGTAGCTAAAAATCGTAGCTTTACAATAGCGGCAAGAAAACAAGG
AGTTGGATTAGCAAAAGTTAGTAAACAAATTAACTTTCTTGAAGAATGGCTATCATCATCACTATTTATACGCACTACTA
GGAAAGTAGAACTAACAGCTAAAGGAGAGGTTTTTCTCAATTATGCTGAAGATATCATAAAACGTTTAGAAGATGCGCAA
AATGATATTGAAAATAGTGATATACAACCAAGAGGAGAGATTGCAGTATCGATAACAGCAGGACTTAATGTCACTTTTTT
TATTGAACACTTTGCTAATTTTTTATCAAAATATGATCAAGTAAAATTAAATATACATAATATTAATTCGCCACTTACAG
TTTTAGAAGGTACTTGTGATGTTTCTATAAGTTCTATAGATGTTTCTGATCCTAGATTAGTCAAATATATCTTTTGCTCA
TTCAAGCGTAAATTATATGCTTCGCCTAAATATTTAGAAAAGCGAGGAGTACCTAGTTGTTTGGCAGATTTGTCGAAGCA
TAATACTTTGGTAAATACTCTTACTCATCCTAAGGGATGGCAGTTTGGTAAATCATCTGTAAATTTAAATTATAATTACC
TATCAAGTTCTACCGATGAGTTAAAAAATGCAGCTATACATGGACTTGGGATTATATGGTCTATTGATCCCTTAGTTAGA
CAAGAGGTTAGCTCTGGACAGTTAGTCGAAATCCAAATTGATGAAGCTCAAGAAGATGTTAACTTATATTGCTATTTTCT
GCAGACATCAAAACAAGACAAAAGACGAATACTAGCTGAGTACTTATTCGAGAATGTAACTATATTATAA

Upstream 100 bases:

>100_bases
TTTTAAATCTAAAAATATCTTATATATATTTTCACACTAAAATTGTTTTAAAAAAACATATAAAATAGTAATTATATCTT
TCCAAACAGGAAATAATAAT

Downstream 100 bases:

>100_bases
TTATTTAATTGGTATCATAACTTCATTAGTACGTAAAAATGGTATTGTCCATGGCGGATTGTAACCAGCTGCTTCAGGTT
GACCAACTATCTGGTAATTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDKFECMKSFILVAKNRSFTIAARKQGVGLAKVSKQINFLEEWLSSSLFIRTTRKVELTAKGEVFLNYAEDIIKRLEDAQ
NDIENSDIQPRGEIAVSITAGLNVTFFIEHFANFLSKYDQVKLNIHNINSPLTVLEGTCDVSISSIDVSDPRLVKYIFCS
FKRKLYASPKYLEKRGVPSCLADLSKHNTLVNTLTHPKGWQFGKSSVNLNYNYLSSSTDELKNAAIHGLGIIWSIDPLVR
QEVSSGQLVEIQIDEAQEDVNLYCYFLQTSKQDKRRILAEYLFENVTIL

Sequences:

>Translated_289_residues
MDKFECMKSFILVAKNRSFTIAARKQGVGLAKVSKQINFLEEWLSSSLFIRTTRKVELTAKGEVFLNYAEDIIKRLEDAQ
NDIENSDIQPRGEIAVSITAGLNVTFFIEHFANFLSKYDQVKLNIHNINSPLTVLEGTCDVSISSIDVSDPRLVKYIFCS
FKRKLYASPKYLEKRGVPSCLADLSKHNTLVNTLTHPKGWQFGKSSVNLNYNYLSSSTDELKNAAIHGLGIIWSIDPLVR
QEVSSGQLVEIQIDEAQEDVNLYCYFLQTSKQDKRRILAEYLFENVTIL
>Mature_289_residues
MDKFECMKSFILVAKNRSFTIAARKQGVGLAKVSKQINFLEEWLSSSLFIRTTRKVELTAKGEVFLNYAEDIIKRLEDAQ
NDIENSDIQPRGEIAVSITAGLNVTFFIEHFANFLSKYDQVKLNIHNINSPLTVLEGTCDVSISSIDVSDPRLVKYIFCS
FKRKLYASPKYLEKRGVPSCLADLSKHNTLVNTLTHPKGWQFGKSSVNLNYNYLSSSTDELKNAAIHGLGIIWSIDPLVR
QEVSSGQLVEIQIDEAQEDVNLYCYFLQTSKQDKRRILAEYLFENVTIL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=253, Percent_Identity=28.8537549407115, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=26.2068965517241, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=24.3055555555556, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87081978, Length=283, Percent_Identity=26.1484098939929, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790011, Length=263, Percent_Identity=26.615969581749, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787128, Length=267, Percent_Identity=25.4681647940075, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789173, Length=255, Percent_Identity=25.0980392156863, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787589, Length=275, Percent_Identity=22.5454545454545, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789639, Length=191, Percent_Identity=24.6073298429319, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=123, Percent_Identity=31.7073170731707, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788706, Length=256, Percent_Identity=23.046875, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32820; Mature: 32820

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFECMKSFILVAKNRSFTIAARKQGVGLAKVSKQINFLEEWLSSSLFIRTTRKVELTA
CCHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEE
KGEVFLNYAEDIIKRLEDAQNDIENSDIQPRGEIAVSITAGLNVTFFIEHFANFLSKYDQ
CCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHE
VKLNIHNINSPLTVLEGTCDVSISSIDVSDPRLVKYIFCSFKRKLYASPKYLEKRGVPSC
EEEEEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHH
LADLSKHNTLVNTLTHPKGWQFGKSSVNLNYNYLSSSTDELKNAAIHGLGIIWSIDPLVR
HHHHHHCCHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCEEEEEECCHHHH
QEVSSGQLVEIQIDEAQEDVNLYCYFLQTSKQDKRRILAEYLFENVTIL
HHCCCCCEEEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKFECMKSFILVAKNRSFTIAARKQGVGLAKVSKQINFLEEWLSSSLFIRTTRKVELTA
CCHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEE
KGEVFLNYAEDIIKRLEDAQNDIENSDIQPRGEIAVSITAGLNVTFFIEHFANFLSKYDQ
CCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHE
VKLNIHNINSPLTVLEGTCDVSISSIDVSDPRLVKYIFCSFKRKLYASPKYLEKRGVPSC
EEEEEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHH
LADLSKHNTLVNTLTHPKGWQFGKSSVNLNYNYLSSSTDELKNAAIHGLGIIWSIDPLVR
HHHHHHCCHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCEEEEEECCHHHH
QEVSSGQLVEIQIDEAQEDVNLYCYFLQTSKQDKRRILAEYLFENVTIL
HHCCCCCEEEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]