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The map label for this gene is gmhA [H]

Identifier: 134302731

GI number: 134302731

Start: 1816356

End: 1816952

Strand: Direct

Name: gmhA [H]

Synonym: FTW_1936

Alternate gene names: 134302731

Gene position: 1816356-1816952 (Clockwise)

Preceding gene: 134302730

Following gene: 134302732

Centisome position: 95.67

GC content: 35.18

Gene sequence:

>597_bases
ATGACTTCTTTAGATAAAATCAATAGTTATTTTGAAAGTAGTATTCAAGCTAAAATAGAAACTGCAAATGCACTACCTCC
AGCTATTGCGCAAGCTGCAAAAGCTATGGTTTCTTGTCTAGAAAATGGTGGAAAAGTCCTAGTTTGTGGCAATGGCAGTT
CAGGAGTTATCGCTCAGCATTTTACATCTAAATTATTAAATCATTTTGAGATGGAGCGTCCTCCTCTTCCTGCAATAGCT
TTGACAGGAGATGTTGCAACTATTACAGCTGTTGGTAATCATTATGGTTTTTCACAAATTTTTGCAAAACAAGTTGCTGC
TCTAGGTAATGAAGATGATATTTTATTAGTTATTACAACTAGTGGTGATTCTGAGAATATCCTTAGTGCTGTAGAAGAGG
CACATGATCTGGAAATGAAAGTAATAGCATTAACTGGTGGCAGTGGCGGAGCACTGCAGAATATGTATAATACCGATGAT
ATTGAACTAAGAGTGCCATCAGATAATATAGCAAATATTCAAGAAAATCATTTTCTCATAGTTCATTGCTTATGTGATAT
TATCGATCAGAAATTATTTGCAGGCTTAGAAGACTAG

Upstream 100 bases:

>100_bases
TTATTAGAGCCTTAGATTAGTCTGAAATACTCAGTATTACACTAGCTATCAAAAATCTAATATAGTAAAATTTTATTAAC
AGATAAGCTTAGAGAAAAAA

Downstream 100 bases:

>100_bases
TATAACGATGTTTAGACCAATAACTAAAAATCTATGTTTATTAATAGCTGCGTTTAGTTTATCAGCATGTGGAATTATAC
AACCATACACAGCTCCTGTA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTSLDKINSYFESSIQAKIETANALPPAIAQAAKAMVSCLENGGKVLVCGNGSSGVIAQHFTSKLLNHFEMERPPLPAIA
LTGDVATITAVGNHYGFSQIFAKQVAALGNEDDILLVITTSGDSENILSAVEEAHDLEMKVIALTGGSGGALQNMYNTDD
IELRVPSDNIANIQENHFLIVHCLCDIIDQKLFAGLED

Sequences:

>Translated_198_residues
MTSLDKINSYFESSIQAKIETANALPPAIAQAAKAMVSCLENGGKVLVCGNGSSGVIAQHFTSKLLNHFEMERPPLPAIA
LTGDVATITAVGNHYGFSQIFAKQVAALGNEDDILLVITTSGDSENILSAVEEAHDLEMKVIALTGGSGGALQNMYNTDD
IELRVPSDNIANIQENHFLIVHCLCDIIDQKLFAGLED
>Mature_197_residues
TSLDKINSYFESSIQAKIETANALPPAIAQAAKAMVSCLENGGKVLVCGNGSSGVIAQHFTSKLLNHFEMERPPLPAIAL
TGDVATITAVGNHYGFSQIFAKQVAALGNEDDILLVITTSGDSENILSAVEEAHDLEMKVIALTGGSGGALQNMYNTDDI
ELRVPSDNIANIQENHFLIVHCLCDIIDQKLFAGLED

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=194, Percent_Identity=47.9381443298969, Blast_Score=190, Evalue=7e-50,
Organism=Escherichia coli, GI1786416, Length=166, Percent_Identity=44.578313253012, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21057; Mature: 20926

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLDKINSYFESSIQAKIETANALPPAIAQAAKAMVSCLENGGKVLVCGNGSSGVIAQH
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
FTSKLLNHFEMERPPLPAIALTGDVATITAVGNHYGFSQIFAKQVAALGNEDDILLVITT
HHHHHHHHHHCCCCCCCEEEEECCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEC
SGDSENILSAVEEAHDLEMKVIALTGGSGGALQNMYNTDDIELRVPSDNIANIQENHFLI
CCCCHHHHHHHHHHHCCEEEEEEEECCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCEEH
VHCLCDIIDQKLFAGLED
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSLDKINSYFESSIQAKIETANALPPAIAQAAKAMVSCLENGGKVLVCGNGSSGVIAQH
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
FTSKLLNHFEMERPPLPAIALTGDVATITAVGNHYGFSQIFAKQVAALGNEDDILLVITT
HHHHHHHHHHCCCCCCCEEEEECCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEC
SGDSENILSAVEEAHDLEMKVIALTGGSGGALQNMYNTDDIELRVPSDNIANIQENHFLI
CCCCHHHHHHHHHHHCCEEEEEEEECCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCEEH
VHCLCDIIDQKLFAGLED
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA