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The map label for this gene is tadA [H]

Identifier: 134302708

GI number: 134302708

Start: 1790608

End: 1791069

Strand: Reverse

Name: tadA [H]

Synonym: FTW_1907

Alternate gene names: 134302708

Gene position: 1791069-1790608 (Counterclockwise)

Preceding gene: 134302712

Following gene: 134302707

Centisome position: 94.34

GC content: 35.28

Gene sequence:

>462_bases
ATGTCTAATTATTCAGATCAAGATATTTTTTTTATGCAAAAAGCTTATCAGCAGGCATTGTTAGCTTATCAAGCTGGTGA
AGTTCCGATAGGTGCAGTGCTTGTCAGGGATGATCAAATAATTGTACAAAATTTTAACCAAACTATAGGTTTAAATGATC
CAACAGCACATGCAGAAATCTTGGTTTTACGCTCAGCAGCATTAAAGCTAGGCAACTACAGATTAGTCAATACAAAATTG
TATGTTACTTTAGAGCCATGTATAATGTGTTTGGGTGGTTTGATTCAGGCAAGAGTACCTGAGCTGGTTTATGCTTGTGA
TGATAGTCGAGTAGGAGCTTTTTCACGTGAAAAACTTCACCACAATAAGAATATTAACCATAATCTTGGAGTAACAGCTG
GAGTAATGGCTGATGAATGTGGCAAACTGCTAAAAGATTTTTTTAAACAAAGAAGAAATTAG

Upstream 100 bases:

>100_bases
TACCCACTGGATATTATATAAAAAGTACTAGCAAACAATTATGTAATGTATTATCTTATCTAAGAGATTCAAATTCTTCA
AGAAGAAAATACTAAAACTT

Downstream 100 bases:

>100_bases
ATTATGAAAAACGAAAAAATTGTTGTTTTATATGGTGGCGACTCTCCAGAAAGAGAAGTTTCTTTGAAATCTGGTAAAGC
AGTTTTGGATTCTTTAATAA

Product: cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSNYSDQDIFFMQKAYQQALLAYQAGEVPIGAVLVRDDQIIVQNFNQTIGLNDPTAHAEILVLRSAALKLGNYRLVNTKL
YVTLEPCIMCLGGLIQARVPELVYACDDSRVGAFSREKLHHNKNINHNLGVTAGVMADECGKLLKDFFKQRRN

Sequences:

>Translated_153_residues
MSNYSDQDIFFMQKAYQQALLAYQAGEVPIGAVLVRDDQIIVQNFNQTIGLNDPTAHAEILVLRSAALKLGNYRLVNTKL
YVTLEPCIMCLGGLIQARVPELVYACDDSRVGAFSREKLHHNKNINHNLGVTAGVMADECGKLLKDFFKQRRN
>Mature_152_residues
SNYSDQDIFFMQKAYQQALLAYQAGEVPIGAVLVRDDQIIVQNFNQTIGLNDPTAHAEILVLRSAALKLGNYRLVNTKLY
VTLEPCIMCLGGLIQARVPELVYACDDSRVGAFSREKLHHNKNINHNLGVTAGVMADECGKLLKDFFKQRRN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=153, Percent_Identity=28.1045751633987, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=44.1558441558442, Blast_Score=147, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=29.5302013422819, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=115, Percent_Identity=32.1739130434783, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325319, Length=150, Percent_Identity=32, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=34.4827586206897, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17128; Mature: 16997

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYSDQDIFFMQKAYQQALLAYQAGEVPIGAVLVRDDQIIVQNFNQTIGLNDPTAHAEI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCHHHH
LVLRSAALKLGNYRLVNTKLYVTLEPCIMCLGGLIQARVPELVYACDDSRVGAFSREKLH
HHHHHHHHHHCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHH
HNKNINHNLGVTAGVMADECGKLLKDFFKQRRN
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNYSDQDIFFMQKAYQQALLAYQAGEVPIGAVLVRDDQIIVQNFNQTIGLNDPTAHAEI
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCHHHH
LVLRSAALKLGNYRLVNTKLYVTLEPCIMCLGGLIQARVPELVYACDDSRVGAFSREKLH
HHHHHHHHHHCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHH
HNKNINHNLGVTAGVMADECGKLLKDFFKQRRN
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]