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The map label for this gene is oxaA

Identifier: 134302668

GI number: 134302668

Start: 1741380

End: 1743035

Strand: Direct

Name: oxaA

Synonym: FTW_1856

Alternate gene names: 134302668

Gene position: 1741380-1743035 (Clockwise)

Preceding gene: 134302667

Following gene: 134302669

Centisome position: 91.73

GC content: 33.82

Gene sequence:

>1656_bases
ATGAAAGCTAATCATATAAGAATATTACTGTTAGTCACAATAGCAATAATGTTTATCTCGTTGATGGGAAAATGGGAGCA
AACATTCCCTGCTGACAATACTAAACAGCAAACATCAGCCACACAAAATAATAGTCACTACGACAATGCAGATTCAAGCA
CAAATACTGATGTAACTACAACTGATGCAAAAAGCTCTTTAGCTAAAGAGACTAATTTTTCTAAGTATGATAATGCTAAA
AGTATCACAATTAATACTGGAGTTTTTAAAGATGTAAAAGTTAGTCTACTAGATGGTGCAATTATATCAGCATCTTTAAA
AGACTACAGTATCAGTCTTGATGATAAGACTCCGATGAGTCTACTTACAGATAAATCAGGTTCTGAATATATTGCTAAGA
GCACGATAGTTGTAAATAAGCAACCTATTAGTGTTAATTTTGAAGACCAAGGCATCAAAATAGAGAATGGCAAACAAATC
CTAACGCTAACTGGTAGTGCTGATGGCTTGCAAATAACTAGAACATATACCTTTGATGATACTAAATACAATATATCAGT
GTCACAAAACATAAAAAATACAACATCTGCACCAGTTAATGTAATTGTTGATGATTCATTTGCTAGAGATTTTGATCCTG
CTGGTGATAGCTTTAGCTTATTAAATGCTCATAGCTATACTTTTACAGGTGTTGCATACTCTACAGCTAAAGATAGCTTT
AGAAAAGAATCCTTTAAAGATATCTCAAAAACTAATGGTCAGCCAACAGTAATAAATAGTGATGGTCAAGGTTGGGTTGC
ATTTTTACAACATTACTTTGTAAGTGCATGGATACCACAATCTACTAATGCAAAAATTTATTATAAAAACCTAAATGGTG
ATGTATTCGAAGCTGGAGCATTTACAGGTGCGACAATAGCACCAAACCAGTCAGAAAATATTTCTTCTATTTTATATACT
GGTCCAATAATAAAAGCCAATCTAGTAGACTTAGCACCAAATCTAGAAAAAACACTTGACTATGGAATGTTGTCTTTCTT
CTCAGAAATAATTTTCTGGGTTATGAATCACATACATTCGCTAGTTGGTAACTGGGGCTTAGCAATTATTTTAGTAACAT
GTTTGATTAAACTTATTTTCTACCCTCTTTCTGCGAAGAGCTATCGCTCTATGGCAAAAATGAGAATGCTACAGCCTAGA
ATTAAGCGTCTGCAAGAAACATACAAAGATGATCGTCAAGCTCTTGGTAAGAAGATGATGGAGTTGTACAAAGAAGAGAA
AGTAAACCCACTTAGTGGCTGTTTGCCTATGCTTATACAGATTCCAATTTTCATCTCATTATACTGGGTATTACTCGAAT
CCGTAGAGCTAAGACAAGCACCTTTTATATTCTGGATTCATGATTTATCGATGAAAGATCCATATTTTGTACTTCCAGTG
CTAATGGGATTATCAATGTTTTTACAACAAAAATTATCACCAGCTCCAGCTGATCCTATGCAGGCAAAAGTAATGATGTT
TTTACCAGTAATATTTACATTCCTGTTCGCATCGTTCCCATCTGGTCTAGTATTATATTGGCTGACGAATAACCTAATCA
GTATTTCACAACAGTGGATTATTACAAGACACTATCAAGCCACTCATAAAAAATAA

Upstream 100 bases:

>100_bases
TGTACTTAACTACACGTAGACTCTTGAGGTGTCATCCACTCTCAAAAAGAGATTACTACGACCTGGTTCCTTGTAAAAAT
AAAAAAGGTTAAAATAAACA

Downstream 100 bases:

>100_bases
ATATACATGGATAAATCTCTACTTAAACCAAAATATTGGGGTATATGGATTATAATTTGGATCGCCAAGTTTATAGTAAA
TATACTTCCATACAAAATGC

Product: inner-membrane protein of unknown function

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTTTDAKSSLAKETNFSKYDNAK
SITINTGVFKDVKVSLLDGAIISASLKDYSISLDDKTPMSLLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENGKQI
LTLTGSADGLQITRTYTFDDTKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGAFTGATIAPNQSENISSILYT
GPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHSLVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPR
IKRLQETYKDDRQALGKKMMELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWIITRHYQATHKK

Sequences:

>Translated_551_residues
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTTTDAKSSLAKETNFSKYDNAK
SITINTGVFKDVKVSLLDGAIISASLKDYSISLDDKTPMSLLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENGKQI
LTLTGSADGLQITRTYTFDDTKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGAFTGATIAPNQSENISSILYT
GPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHSLVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPR
IKRLQETYKDDRQALGKKMMELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWIITRHYQATHKK
>Mature_551_residues
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTTTDAKSSLAKETNFSKYDNAK
SITINTGVFKDVKVSLLDGAIISASLKDYSISLDDKTPMSLLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENGKQI
LTLTGSADGLQITRTYTFDDTKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGAFTGATIAPNQSENISSILYT
GPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHSLVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPR
IKRLQETYKDDRQALGKKMMELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWIITRHYQATHKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=558, Percent_Identity=36.9175627240143, Blast_Score=344, Evalue=7e-96,
Organism=Drosophila melanogaster, GI24662345, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356443, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_FRAT1 (Q14JK8)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_666418.1
- STRING:   Q14JK8
- GeneID:   4199108
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF0233c
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   AYSTAND
- PhylomeDB:   Q14JK8
- ProtClustDB:   CLSK934427
- BioCyc:   FTUL393115:FTF0233C-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 61869; Mature: 61869

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe94e804)-; HASH(0xf9827e8)-; HASH(0xf9de994)-; HASH(0xfa13d30)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTT
CCCCCEEHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEE
TDAKSSLAKETNFSKYDNAKSITINTGVFKDVKVSLLDGAIISASLKDYSISLDDKTPMS
CCHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCEEEECCCEEEECCCCCCHH
LLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENGKQILTLTGSADGLQITRTYTFDD
HHCCCCCCCEEEEEEEEEECCCEEEEECCCCEEEECCCEEEEEECCCCCEEEEEEEEECC
TKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
CEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCEEEEEEEEHHHHHHH
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGA
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCC
FTGATIAPNQSENISSILYTGPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHS
CCCCEECCCCCCCCHHHEEECCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPRIKRLQETYKDDRQALGKKMM
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWI
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHE
ITRHYQATHKK
EEEECHHCCCH
>Mature Secondary Structure
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTT
CCCCCEEHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEE
TDAKSSLAKETNFSKYDNAKSITINTGVFKDVKVSLLDGAIISASLKDYSISLDDKTPMS
CCHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCEEEECCCEEEECCCCCCHH
LLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENGKQILTLTGSADGLQITRTYTFDD
HHCCCCCCCEEEEEEEEEECCCEEEEECCCCEEEECCCEEEEEECCCCCEEEEEEEEECC
TKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
CEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCEEEEEEEEHHHHHHH
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGA
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCC
FTGATIAPNQSENISSILYTGPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHS
CCCCEECCCCCCCCHHHEEECCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPRIKRLQETYKDDRQALGKKMM
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWI
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHE
ITRHYQATHKK
EEEECHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA