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The map label for this gene is lolB2 [H]

Identifier: 134302646

GI number: 134302646

Start: 1719767

End: 1720390

Strand: Direct

Name: lolB2 [H]

Synonym: FTW_1829

Alternate gene names: 134302646

Gene position: 1719767-1720390 (Clockwise)

Preceding gene: 134302645

Following gene: 134302647

Centisome position: 90.59

GC content: 31.25

Gene sequence:

>624_bases
ATGTCAAAGTTAAAAATAGATACAAAGCGCAGATTTAGTTTACTTATTGCTTTAGTACTAATTATCTCATTATCATCTTG
TGCTACAACGCAAACTAATGTTACAACTAAAACAGTTTTTAATCAAGAGACTACTTACCATAACTTACTTAAGCTTAAAA
AATGGCAAGCCAATGGTGTTATTGGTATTATCTATGATAATCAGGCTGAATCTGCTAATTATACATACTTACAAGATGGT
GATAATTTTAGTATCAAACTTTATGGTCCATTAGGAATAGGTAGCATTGAAATAAAAGGCGATACGAACAGTGTTTCACT
AGCGAATAGTAAAGGACAAAAGCTAACAGCAAAAGACGCTAAAACTTTGATGTTAGAGCAGTTAGGCTGGTATGTGCCAG
TAGAGGGTCTTAAATACTGGATAAAAGCGATAGCAATACCAAATATTAGGCAAACATCCGAACTAAACACCAATAATCTT
TTAAGTAAACTATCACAAAATGGTTGGAGTATTAGTTATAGTAATTATCAACTAGTTGATTCTAAATATCCCTTACCAAC
AAAGATTAGGATGTCTAGAGATAATCTAACTCTAAAAATCGTTATAAAATCATGGCAAATATAA

Upstream 100 bases:

>100_bases
ACTCTTGAGTCAGGTTATATGTATTTAGGTTCACCAGCTAAAAAGGTTAGACCAATAAGTGAGCATGAAAGACAAATTAT
TAAAGAAAATGCTGAACACT

Downstream 100 bases:

>100_bases
AAGCTAAAAAATACTATAGTTATGCAAAGATAAATCTATTTTTGCATATATTAAACAAACGTACAGATGGTTACCATAAT
TTACAGACTTGGTTTACCTT

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTTKTVFNQETTYHNLLKLKKWQANGVIGIIYDNQAESANYTYLQDG
DNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNL
LSKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI

Sequences:

>Translated_207_residues
MSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTTKTVFNQETTYHNLLKLKKWQANGVIGIIYDNQAESANYTYLQDG
DNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNL
LSKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI
>Mature_206_residues
SKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTTKTVFNQETTYHNLLKLKKWQANGVIGIIYDNQAESANYTYLQDGD
NFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNLL
SKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

Organism=Escherichia coli, GI1787460, Length=202, Percent_Identity=25.2475247524752, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 23313; Mature: 23182

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTTKTVFNQETTYHNLLKLKKWQANGV
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHEEEECCCCE
IGIIYDNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDA
EEEEECCCCCCCCEEEEECCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCCEEEHHHH
KTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNLLSKLSQNGWSISYSNYQLVD
HHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCEEEEC
SKYPLPTKIRMSRDNLTLKIVIKSWQI
CCCCCCEEEEEECCCEEEEEEEEECCC
>Mature Secondary Structure 
SKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTTKTVFNQETTYHNLLKLKKWQANGV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHEEEECCCCE
IGIIYDNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDA
EEEEECCCCCCCCEEEEECCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCCEEEHHHH
KTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNLLSKLSQNGWSISYSNYQLVD
HHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCEEEEC
SKYPLPTKIRMSRDNLTLKIVIKSWQI
CCCCCCEEEEEECCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA