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The map label for this gene is pheC [H]

Identifier: 134302629

GI number: 134302629

Start: 1701324

End: 1702064

Strand: Direct

Name: pheC [H]

Synonym: FTW_1809

Alternate gene names: 134302629

Gene position: 1701324-1702064 (Clockwise)

Preceding gene: 134302628

Following gene: 134302632

Centisome position: 89.62

GC content: 28.48

Gene sequence:

>741_bases
ATGAAAAAAACCGTATTTACATTTATAACTGCTATTGCAGTTATGATTTCTAGCGCATATGCTGATATTACCGTAGGAAC
AACAGGCGATTATGCGCCATTTTCAGTTTATAATCCCAAAGATAATAAATACTCTAGTAAGGATATAAAGCTCATAGAAG
CTTTTGCAAAAAACAAAAAAGAACAAGTAAAGTTTGTCAAAACTTCTTGGGCAACTGCTGAGAATGATTTAAAAAGCAAT
AAATTTGATGTTTTTGTTGGAGGAATGACAATAACTCCTGAACGTCAAAAAGAATTTGTCTTTTCAAACCCATTAATATC
ATTTAATAAGGCAGCTATGACTGCTTGTAAAAAGTTAAATAAGTATAAAACTTTTAATGATATTGATAATCCAAAAACAT
TAGTTATTGAAAATAGAGGTGGTACAAATCAAGTATTTGCATTACAGAAATTAAAAAATGCTAAAGTGCTAATAATAAGC
GATAATAACCAAGCAATAAACTCTATCATAAAAGGTATAGATAATATTCATCCTGATATTATGTTTACAGATACTTTAGA
AATAGCTTATCAACATTCTAAGAACCATAAGATATGCCAAGTACCTGTAAAAGTTGATGATAATCAATACTACAAAGCCT
TTATGTTTAATAATACATCACAAGGTAAGAAAATTGCTCAAGAGTTTGACAACTGGCTTAATAATAACCCGACTATCCTT
AAAAAATATACAAAATCTTAA

Upstream 100 bases:

>100_bases
AAAAGAAGATCAATCAAAATAAAAATCATTATCTAAGCTATTCTATTTTTTGTTCTTTGGTGTAAAATCTTATCAGTAAA
AATCATAATCTTTAAAAAAA

Downstream 100 bases:

>100_bases
ATAAAGCTTTGTAATTATCATTTATCATAAGAAAATACCTCTATAATCTATCTTGAGTAAACTCTGAATGCTTAAAGCGT
ATCGTATTACCTTAATTTTT

Product: cyclohexadienyl dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKKTVFTFITAIAVMISSAYADITVGTTGDYAPFSVYNPKDNKYSSKDIKLIEAFAKNKKEQVKFVKTSWATAENDLKSN
KFDVFVGGMTITPERQKEFVFSNPLISFNKAAMTACKKLNKYKTFNDIDNPKTLVIENRGGTNQVFALQKLKNAKVLIIS
DNNQAINSIIKGIDNIHPDIMFTDTLEIAYQHSKNHKICQVPVKVDDNQYYKAFMFNNTSQGKKIAQEFDNWLNNNPTIL
KKYTKS

Sequences:

>Translated_246_residues
MKKTVFTFITAIAVMISSAYADITVGTTGDYAPFSVYNPKDNKYSSKDIKLIEAFAKNKKEQVKFVKTSWATAENDLKSN
KFDVFVGGMTITPERQKEFVFSNPLISFNKAAMTACKKLNKYKTFNDIDNPKTLVIENRGGTNQVFALQKLKNAKVLIIS
DNNQAINSIIKGIDNIHPDIMFTDTLEIAYQHSKNHKICQVPVKVDDNQYYKAFMFNNTSQGKKIAQEFDNWLNNNPTIL
KKYTKS
>Mature_246_residues
MKKTVFTFITAIAVMISSAYADITVGTTGDYAPFSVYNPKDNKYSSKDIKLIEAFAKNKKEQVKFVKTSWATAENDLKSN
KFDVFVGGMTITPERQKEFVFSNPLISFNKAAMTACKKLNKYKTFNDIDNPKTLVIENRGGTNQVFALQKLKNAKVLIIS
DNNQAINSIIKGIDNIHPDIMFTDTLEIAYQHSKNHKICQVPVKVDDNQYYKAFMFNNTSQGKKIAQEFDNWLNNNPTIL
KKYTKS

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1787085, Length=211, Percent_Identity=29.8578199052133, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 1180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 27928; Mature: 27928

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVFTFITAIAVMISSAYADITVGTTGDYAPFSVYNPKDNKYSSKDIKLIEAFAKNKK
CCHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCH
EQVKFVKTSWATAENDLKSNKFDVFVGGMTITPERQKEFVFSNPLISFNKAAMTACKKLN
HHHEEHHHHCCCCCCCCCCCCEEEEECCEEECCCHHHHEEECCCCCCCHHHHHHHHHHHH
KYKTFNDIDNPKTLVIENRGGTNQVFALQKLKNAKVLIISDNNQAINSIIKGIDNIHPDI
HCCCCCCCCCCCEEEEECCCCCCHHHEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCE
MFTDTLEIAYQHSKNHKICQVPVKVDDNQYYKAFMFNNTSQGKKIAQEFDNWLNNNPTIL
EEECCEEEEEECCCCCEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEE
KKYTKS
EEECCC
>Mature Secondary Structure
MKKTVFTFITAIAVMISSAYADITVGTTGDYAPFSVYNPKDNKYSSKDIKLIEAFAKNKK
CCHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCH
EQVKFVKTSWATAENDLKSNKFDVFVGGMTITPERQKEFVFSNPLISFNKAAMTACKKLN
HHHEEHHHHCCCCCCCCCCCCEEEEECCEEECCCHHHHEEECCCCCCCHHHHHHHHHHHH
KYKTFNDIDNPKTLVIENRGGTNQVFALQKLKNAKVLIISDNNQAINSIIKGIDNIHPDI
HCCCCCCCCCCCEEEEECCCCCCHHHEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCE
MFTDTLEIAYQHSKNHKICQVPVKVDDNQYYKAFMFNNTSQGKKIAQEFDNWLNNNPTIL
EEECCEEEEEECCCCCEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEE
KKYTKS
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]