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The map label for this gene is htpG [H]

Identifier: 134302558

GI number: 134302558

Start: 1637675

End: 1639561

Strand: Direct

Name: htpG [H]

Synonym: FTW_1729

Alternate gene names: 134302558

Gene position: 1637675-1639561 (Clockwise)

Preceding gene: 134302557

Following gene: 134302559

Centisome position: 86.26

GC content: 33.12

Gene sequence:

>1887_bases
ATGTCAGAAAAAAAATATACTTTTGAAACTGAGGTAGATAAATTACTTCATCTTGTAATTCACTCACTATATTCAAACCG
TGAGATATTTTTAAGAGAGCTTGTATCTAATAGTTCTGATGCTATCGAGAAATTAAGATATGAGAGTATTTCAAACGCAG
CTTTAAACGAAGATGATACTGATTATGCTATCAGAATTGATTTTGATAAAGATGCAAAAACTATAACAGTTAGCGATAAT
GGTATCGGTATGACTGAAGAAGAAGTCATCGAAAATCTCGGCACAATTGCTAAGTCAGGGACTAAGAAATTCTTAGAAAG
TTTAACTGGTGATAAGAGCAAAGATAACGAGCTGATTGGTCAGTTTGGAGTTGGTTTTTATTCATCATTTATAGTTGCTG
ATAAAGTTACGGTTAGAACTAGAAAAGCAGGTCAAGATAAATCTCAAGCTACTAAGTGGGTTTCTGATGCACAGAATGGT
TTTACAGTAGAGACAATAACTAAAGAAAAGCGTGGTACAGAAGTAATTCTTCATATTAAGAAAGAACATTTGGATTTGCT
AGAATATCACGTGCTTAAAGGTTTAGTCAATAAGTACTCAGATTGTATCAATACACCAATTCAGATGAAGAAGGTTGAGT
ATGATAAAGATGGTAAGCAAACTGTTAAAGATGAATATGAAACAGTAAATAATACTAAAGCTATTTGGCTAAGATCTAAA
GATGAAGTTACTGATGAGGAATATCAAGAGTTCTATAAGTATATTTCCCATGATTTTGCTGATGCTTTAATGTGGATACA
TAATAAGGTTGAAGGTAATCTTGAATATAATAGCTTACTTTATATTCCACAAAATAAACCTTTTGATTTCTGGAACAGAG
ATAAAGACTATGGTTTATCACTGTATGTGCGTAGAGTCTTTATTATGGAGAATAAGGAATTATTACCTCCATATTTAAGA
TTTGTTAAGGGTGTCATTGATTCTGCTGATTTACCACTTAATGTATCACGTGAGATATTACAGCATAATAAAGTTATTGA
TAAGATTAAAAAAGCAATAACGACTAAAATCCTAAGCGAACTTAAGAAGCTAGCTAGTAAGGATAAAGAAAAATACCAAA
AATTCTGGGATAGTTTTGGTCAAGTGCTTAAAGAAGGTGTTTCTGATGATTACTCAAACAAGGAAAAGATTGCGGGCTTA
TTAAGATTTGCTACTACTCAAAGTGGCGACTCTAAGCAAACAGTATCTTTGGCTGATTATATTTCGCGTATGAAAGAAGG
TCAAGATACTATTTACTATATTACTTCTGATAGTTATAAGGCTGCTGCGAATAATCCACAGCTTGAAGCATTCAAGAAGA
AAGGTATCGAGGTTATCTTGATGACAGATAGAATCGATGAATGGATGATGTCTACTTTGACTGAGTTTGATGGCAAGCAT
ATGAAATCAATTATCAAAGGTGATATTGATCTTGATAAGTTTGAAACTCCAGAGAACAAAGAGAAATTTGAGAAAGAAGC
GAAAGACTTTGAGAAAGTTCTAAAAGAAATTAAAGAAGTTCTAAAAGATAAGGTCGAGGATGTACGTCTATCTAAGCGTC
TGACAGATTCTCCAAGTTGTGTGGTTGTTAATGACTATGGTATGAGTCTACACATGCAAAAGATGATGGAAGAGGCTGGA
CAGTCATTTATGCCTGGTATGGGTATGAAACCAATCCTTGAGCTTAATGCTGAGCATAATTTGGTGCAGAAGCTTAAAAA
TGAAGCAGATACAGAAATATTTGCTGATTTATCTGAGCTTTTACTTCTTCAAGCTATGTTTGTAGAAGGTGCTAAGATAG
AAGATCCAATGGCTTTTGTTAAGCTTGTGAATAAATATATCAGATAG

Upstream 100 bases:

>100_bases
CTATATAGATATAAAAATACTTGAAAAAACTAACTTCCACTCTCATATAGTTATTTGTTTAAGATTATTTATAAATGTAT
AACAAGAGAGGGTTATATAA

Downstream 100 bases:

>100_bases
TTTTTTCTTTTCTTTTTATCTTTAAAATTCTTCTTTATAATCTTTTAGTAGTGTTTTAATCTGCTAATATGATTTTATGC
TATCTAAAATTTTTTAAAAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDN
GIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNG
FTVETITKEKRGTEVILHIKKEHLDLLEYHVLKGLVNKYSDCINTPIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSK
DEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLR
FVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGL
LRFATTQSGDSKQTVSLADYISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKH
MKSIIKGDIDLDKFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCVVVNDYGMSLHMQKMMEEAG
QSFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSELLLLQAMFVEGAKIEDPMAFVKLVNKYIR

Sequences:

>Translated_628_residues
MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDN
GIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNG
FTVETITKEKRGTEVILHIKKEHLDLLEYHVLKGLVNKYSDCINTPIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSK
DEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLR
FVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGL
LRFATTQSGDSKQTVSLADYISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKH
MKSIIKGDIDLDKFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCVVVNDYGMSLHMQKMMEEAG
QSFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSELLLLQAMFVEGAKIEDPMAFVKLVNKYIR
>Mature_627_residues
SEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDNG
IGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGF
TVETITKEKRGTEVILHIKKEHLDLLEYHVLKGLVNKYSDCINTPIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSKD
EVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLRF
VKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGLL
RFATTQSGDSKQTVSLADYISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKHM
KSIIKGDIDLDKFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCVVVNDYGMSLHMQKMMEEAGQ
SFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSELLLLQAMFVEGAKIEDPMAFVKLVNKYIR

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=684, Percent_Identity=37.1345029239766, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI155722983, Length=644, Percent_Identity=34.472049689441, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI154146191, Length=411, Percent_Identity=41.3625304136253, Blast_Score=295, Evalue=1e-79,
Organism=Homo sapiens, GI153792590, Length=411, Percent_Identity=41.3625304136253, Blast_Score=293, Evalue=4e-79,
Organism=Homo sapiens, GI20149594, Length=206, Percent_Identity=45.6310679611651, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1786679, Length=623, Percent_Identity=53.1300160513644, Blast_Score=665, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=674, Percent_Identity=39.3175074183976, Blast_Score=453, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17542208, Length=679, Percent_Identity=35.9351988217968, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI115535205, Length=644, Percent_Identity=34.7826086956522, Blast_Score=324, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=436, Percent_Identity=38.302752293578, Blast_Score=268, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6323840, Length=679, Percent_Identity=37.9970544918999, Blast_Score=435, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6325016, Length=683, Percent_Identity=38.2137628111274, Blast_Score=435, Evalue=1e-123,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=39.766081871345, Blast_Score=460, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=683, Percent_Identity=38.6530014641288, Blast_Score=407, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24586016, Length=638, Percent_Identity=34.012539184953, Blast_Score=361, Evalue=1e-100,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72331; Mature: 72200

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDT
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
DYAIRIDFDKDAKTITVSDNGIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIG
CEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGFTVETITKEKRGTEVILHIK
HHHHHHHHHHHHHCCCEEHHHHCCCCHHHHHHHHHHCCCCCEEEEEHHCCCCCEEEEEEH
KEHLDLLEYHVLKGLVNKYSDCINTPIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSK
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEHCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
DEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEECCCCCCCCCCCCCCCCHH
LYVRRVFIMENKELLPPYLRFVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSE
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGLLRFATTQSGDSKQTVSLADY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
ISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKH
HHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCHHH
MKSIIKGDIDLDKFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSC
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVVNDYGMSLHMQKMMEEAGQSFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSEL
EEEECCCCHHHHHHHHHHCCHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LLLQAMFVEGAKIEDPMAFVKLVNKYIR
HHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDT
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
DYAIRIDFDKDAKTITVSDNGIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIG
CEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGFTVETITKEKRGTEVILHIK
HHHHHHHHHHHHHCCCEEHHHHCCCCHHHHHHHHHHCCCCCEEEEEHHCCCCCEEEEEEH
KEHLDLLEYHVLKGLVNKYSDCINTPIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSK
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEHCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
DEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEECCCCCCCCCCCCCCCCHH
LYVRRVFIMENKELLPPYLRFVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSE
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGLLRFATTQSGDSKQTVSLADY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
ISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKH
HHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCHHH
MKSIIKGDIDLDKFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSC
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVVNDYGMSLHMQKMMEEAGQSFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSEL
EEEECCCCHHHHHHHHHHCCHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LLLQAMFVEGAKIEDPMAFVKLVNKYIR
HHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA