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The map label for this gene is glmU [H]

Identifier: 134302529

GI number: 134302529

Start: 1602230

End: 1603597

Strand: Reverse

Name: glmU [H]

Synonym: FTW_1687

Alternate gene names: 134302529

Gene position: 1603597-1602230 (Counterclockwise)

Preceding gene: 134302530

Following gene: 134302528

Centisome position: 84.47

GC content: 34.5

Gene sequence:

>1368_bases
ATGGGTTTATCAGTTGTTATTTTGGCTGCAGGCAAAGGTTCAAGAATGAACTCAAACAAACCAAAGGTTTTACAAACATT
AGCAGCAAAAACGTTGATTGAGCATGTTGTAAGTTCTGTTGAGAAACTAAACCCAGATAATATAGTTGTTGTTACAGGGC
ATCTAAAAGAGCAAGTTGAAGATGCATTGCAAGGAAGAAATATAACATTTGTCTATCAGCAGCAGCAACTTGGTACAGGT
CATGCGGTATTACAGGCATTACCTTACTTAAAAGAACAAAAAGTTCTTATTCTTTATGGGGATGTACCTTTAATTTCAAC
TGAAGTTTTAGAAAACCTTGTTGATACTACCAATGATGATGACCTTGGCGTCTTGACCGCGTTTGTTGAGAATCCTCAAG
GTTTAGGTAGAATTGTTAGAGATAAGTTTGGTGCAGTTACAGAGATTGTTGAAGAAAAAGATGCGAATGATATCCAGCGT
CAAATAAAAGAAATTAATACTGGAATTTATTGTGTCCATAAAAATTTACTGCAAAAATGGTTGCCAGAGATAAAAGCAAA
TAATGTCCAGAAAGAATATTATTTAACAGATATAATCACATTTGCAAAAGCCGATCATGTTTCTATAAATGTAACTCATC
CAATTAATGAGTTTGAAATTTTGGGTGTTAATGATAGAACACAATTAGCTAGTCTTGAGCGAGTTTGGCAAAGAAATGTT
GCTGAAAAGATTATGGCTAAAGGTGTAAGTATTGCTGATCCGAATAGATTTGATGTGCGTGGTAATCTTGATGTTGGTAA
AGATTGCTGGATAGATATTAATGTAATAATCAAAGGTAATGTTAAGCTTGGTAATAATGTTGTCATAGGAGCTAACTGTA
TACTTAAAAATTGTATTATCGAAGATAATGTTAGAATTAAATCTAACAGTATGGTCGATGGTTCTATTATTCGTGAAGGT
GCAATAGTTGGTCCTTTTGCACGTGTTAGACCTGAATGTGATGTTAAAGAGGGTGCTGTTATTGGAAACTTCGTTGAAGC
TAAAAAAACGATTCTTGGCAAAGGTTCAAAAGCATCGCATTTAACTTACCTTGGTGATAGTGAAATTGGTGCTAATTGTA
ATATAGGCGCTGGAGTAATAACTTGTAATTATGATGGGGTTAATAAACATAAAACAGTTATAGGGGATTATGCGTTTATT
GGATCTGATTCACAATTAATAGCTCCAGTTAACATTGGTCAAGGTGCAACTGTTGGTGCTGGATCAACTATTGTAAAAGA
TGTTCCCGCTGATAATCTTGCAATTTCAAGAGCAAGACAGCGTCATATTGATACTTGGCAGAGATCCGTCAAGAAAACAG
ATAAATAA

Upstream 100 bases:

>100_bases
AATATTAAAAATATCTGTGATAGAATGTTAGAAGATCATTATCAAATTATCACGATTTTATTAGAGGAATGTGGTAAGAA
ACTATAAGGAGTTTTTTATT

Downstream 100 bases:

>100_bases
TAAAAAATAAGGTTTGTGTTATGTGTGGAATAGTAGGTGCTAACTCTACAAGAAATGTTACTAATATCTTAATTGAAGGT
TTAAAAAAACTAGAGTACAG

Product: UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MGLSVVILAAGKGSRMNSNKPKVLQTLAAKTLIEHVVSSVEKLNPDNIVVVTGHLKEQVEDALQGRNITFVYQQQQLGTG
HAVLQALPYLKEQKVLILYGDVPLISTEVLENLVDTTNDDDLGVLTAFVENPQGLGRIVRDKFGAVTEIVEEKDANDIQR
QIKEINTGIYCVHKNLLQKWLPEIKANNVQKEYYLTDIITFAKADHVSINVTHPINEFEILGVNDRTQLASLERVWQRNV
AEKIMAKGVSIADPNRFDVRGNLDVGKDCWIDINVIIKGNVKLGNNVVIGANCILKNCIIEDNVRIKSNSMVDGSIIREG
AIVGPFARVRPECDVKEGAVIGNFVEAKKTILGKGSKASHLTYLGDSEIGANCNIGAGVITCNYDGVNKHKTVIGDYAFI
GSDSQLIAPVNIGQGATVGAGSTIVKDVPADNLAISRARQRHIDTWQRSVKKTDK

Sequences:

>Translated_455_residues
MGLSVVILAAGKGSRMNSNKPKVLQTLAAKTLIEHVVSSVEKLNPDNIVVVTGHLKEQVEDALQGRNITFVYQQQQLGTG
HAVLQALPYLKEQKVLILYGDVPLISTEVLENLVDTTNDDDLGVLTAFVENPQGLGRIVRDKFGAVTEIVEEKDANDIQR
QIKEINTGIYCVHKNLLQKWLPEIKANNVQKEYYLTDIITFAKADHVSINVTHPINEFEILGVNDRTQLASLERVWQRNV
AEKIMAKGVSIADPNRFDVRGNLDVGKDCWIDINVIIKGNVKLGNNVVIGANCILKNCIIEDNVRIKSNSMVDGSIIREG
AIVGPFARVRPECDVKEGAVIGNFVEAKKTILGKGSKASHLTYLGDSEIGANCNIGAGVITCNYDGVNKHKTVIGDYAFI
GSDSQLIAPVNIGQGATVGAGSTIVKDVPADNLAISRARQRHIDTWQRSVKKTDK
>Mature_454_residues
GLSVVILAAGKGSRMNSNKPKVLQTLAAKTLIEHVVSSVEKLNPDNIVVVTGHLKEQVEDALQGRNITFVYQQQQLGTGH
AVLQALPYLKEQKVLILYGDVPLISTEVLENLVDTTNDDDLGVLTAFVENPQGLGRIVRDKFGAVTEIVEEKDANDIQRQ
IKEINTGIYCVHKNLLQKWLPEIKANNVQKEYYLTDIITFAKADHVSINVTHPINEFEILGVNDRTQLASLERVWQRNVA
EKIMAKGVSIADPNRFDVRGNLDVGKDCWIDINVIIKGNVKLGNNVVIGANCILKNCIIEDNVRIKSNSMVDGSIIREGA
IVGPFARVRPECDVKEGAVIGNFVEAKKTILGKGSKASHLTYLGDSEIGANCNIGAGVITCNYDGVNKHKTVIGDYAFIG
SDSQLIAPVNIGQGATVGAGSTIVKDVPADNLAISRARQRHIDTWQRSVKKTDK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=451, Percent_Identity=51.219512195122, Blast_Score=460, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 49657; Mature: 49525

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSVVILAAGKGSRMNSNKPKVLQTLAAKTLIEHVVSSVEKLNPDNIVVVTGHLKEQVE
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
DALQGRNITFVYQQQQLGTGHAVLQALPYLKEQKVLILYGDVPLISTEVLENLVDTTNDD
HHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
DLGVLTAFVENPQGLGRIVRDKFGAVTEIVEEKDANDIQRQIKEINTGIYCVHKNLLQKW
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEHHHHHHH
LPEIKANNVQKEYYLTDIITFAKADHVSINVTHPINEFEILGVNDRTQLASLERVWQRNV
HHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHH
AEKIMAKGVSIADPNRFDVRGNLDVGKDCWIDINVIIKGNVKLGNNVVIGANCILKNCII
HHHHHHCCCCCCCCCCEEEECCCCCCCCEEEEEEEEEECCEEECCEEEEECHHHHHHCEE
EDNVRIKSNSMVDGSIIREGAIVGPFARVRPECDVKEGAVIGNFVEAKKTILGKGSKASH
CCCCEEECCCCCCCHHHHCCCEECCHHHCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCE
LTYLGDSEIGANCNIGAGVITCNYDGVNKHKTVIGDYAFIGSDSQLIAPVNIGQGATVGA
EEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCC
GSTIVKDVPADNLAISRARQRHIDTWQRSVKKTDK
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GLSVVILAAGKGSRMNSNKPKVLQTLAAKTLIEHVVSSVEKLNPDNIVVVTGHLKEQVE
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
DALQGRNITFVYQQQQLGTGHAVLQALPYLKEQKVLILYGDVPLISTEVLENLVDTTNDD
HHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
DLGVLTAFVENPQGLGRIVRDKFGAVTEIVEEKDANDIQRQIKEINTGIYCVHKNLLQKW
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEHHHHHHH
LPEIKANNVQKEYYLTDIITFAKADHVSINVTHPINEFEILGVNDRTQLASLERVWQRNV
HHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHH
AEKIMAKGVSIADPNRFDVRGNLDVGKDCWIDINVIIKGNVKLGNNVVIGANCILKNCII
HHHHHHCCCCCCCCCCEEEECCCCCCCCEEEEEEEEEECCEEECCEEEEECHHHHHHCEE
EDNVRIKSNSMVDGSIIREGAIVGPFARVRPECDVKEGAVIGNFVEAKKTILGKGSKASH
CCCCEEECCCCCCCHHHHCCCEECCHHHCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCE
LTYLGDSEIGANCNIGAGVITCNYDGVNKHKTVIGDYAFIGSDSQLIAPVNIGQGATVGA
EEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCC
GSTIVKDVPADNLAISRARQRHIDTWQRSVKKTDK
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA