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The map label for this gene is argS [H]

Identifier: 134302456

GI number: 134302456

Start: 1508789

End: 1510534

Strand: Direct

Name: argS [H]

Synonym: FTW_1604

Alternate gene names: 134302456

Gene position: 1508789-1510534 (Clockwise)

Preceding gene: 134302446

Following gene: 134302465

Centisome position: 79.47

GC content: 35.11

Gene sequence:

>1746_bases
ATGAATATAGAAAATTATTTATCAGAAACTCTTGCAAAGGTGTTCCAAAAGCTAGGTTATGCAGAAAGTTTTGCTAAAGT
TGTAACCTCAACTCGTGAAGATGTTGGACATTTCCAGTGTAATGGCGCTATGCCATTAGCTAAATTCGCCAAAAAACCGC
CTTTGGCAATTGCCGAAGAGATAGTCGAGCATATTGATGCTGAAGATATCTTTGCCAAATTAGAGGTTGCTAAACCAGGC
TTTATCAATATAACTTTAGCACCAAAATTCTTAGCTGATACTACAAATAGATTTTTAAATTCTAATAAATTTGGTGTACA
AAACAACTTACCTAATAGGAAAGTTGTGCTTGATTTTGGTGGTCCAAATGTTGCTAAGCCGATGCACGTTGGACACATTA
GATCTGCACTTTTAGGTGATGCCTTACAAAGAATTCATCGCTTCTGTGGTGATACGGTAGTCTCTGATGTACATTTAGGT
GATTGGGGTACGCAAATGGGTATGCTTATAGAAGAAATAAAACTACAATCGCCTCAACTTGTATATTTTGATGAAAATTA
TACAGGTGAATATCCTACGGAATCACCAGTAACTGTCCAAGAGCTAGCAGAAATCTATCCGCGTGCCTCGAAGAGGTGTA
AATCTGATATAAATGAAATGGAAAAAGCTAGATTAGCTACTTTTGAATTACAACAAGGTCGTAGAGGTTATGTTGCACTT
TGGCAACATTTTGTGAGAATCTCTATCGATGCAGTTAAAAAAGATTTTGATAGTTTAGATGTGCATTTTGACTTATGGTT
AGGTGAAAGTGATGCTAATAAATTTATCGATGAAATGATTAGTTACTTTCAAGCTAATAATTTTATCTATGAAGATGAAG
GTGCTTGGGTTATTGACACAAATAAGGATGGAGTACCACCTCTAATAGTCATCAAAAAAGATGGTGGTGTAATGTATGGT
ACTACGGATCTAGCTACTTTATGGCAGCGTAGCAAAGATCTTGATCCAGATGAAATAATTTATGTAGTTGACAAAAGACA
ATCTCTTCACTTTAAGCAAGTTTTTAGCGTTGCTGAACGGACAAAAGTTGTCAGCGAAAAATGCAAACTTAAACACGTGG
CTTTCGGCACAGTCAATGGTAAAGATGGACGCCCTTTCAAAACCCGTGAAGGTGGCGTAATGCATTTAGCAGATTTGATT
TCTCAAGCAAAAGAATATGCCAAAAATAGAATGCCTGATGAGAATGATGATAGCATTATTGATCAAATAGCTATGGCAAC
AATTAAATTTGGTGACCTAATCAATAACTATGCTAATGATTATTTCTTTGATTTAGAAAAGTTTGCACAGCATGAAGGTA
AAACAGGTCCTTATCTTTTGTATACTGTAGTTAGAGCAAAATCGATCCTTAGAAAAATATTTGGTGACAACTATGATATC
AAATCTCTAGCAAAAGATTATAAAGTTGTAAATGCTCATAATGAATACGAAGAAAAACTCCAACTTCAACTAATACAATT
TCCTATCGCTGTACAAAGAGCTTATGAAAATTCGCAACCTCATCATATTTGCGAGTATGCTTACTCATTAGCTAATAGTT
TTAACAAATTCTACGTTAATTGCCCTATTAATAATCTTGACGATGAGTCATTAAAAAAAGCAAGAATTGCACTATGCATG
GCAACTGTCAAAGCTATGACAATCGCCTCAGATTTAATAGGCATCTCTATTCCCGAGAGAATGTAA

Upstream 100 bases:

>100_bases
ATTGAGTTTTTTAAAATAACCGTGATATTATATATATATTTGAGAAATATTTCCATTCTAATTTAAACTCTAGATACAAC
AAGACAATTGGGCTATTTTA

Downstream 100 bases:

>100_bases
AAGATAAAATTTAACTTATGATGAATACTCTATTTTTGTAGCCCACATATTTTAACTGATTGTAAGCGGAATACTACCAC
TATAGTTGTTACCACCGCTA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEEIVEHIDAEDIFAKLEVAKPG
FINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFGGPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVVSDVHLG
DWGTQMGMLIEEIKLQSPQLVYFDENYTGEYPTESPVTVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVAL
WQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDTNKDGVPPLIVIKKDGGVMYG
TTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAERTKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLI
SQAKEYAKNRMPDENDDSIIDQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTVVRAKSILRKIFGDNYDI
KSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVNCPINNLDDESLKKARIALCM
ATVKAMTIASDLIGISIPERM

Sequences:

>Translated_581_residues
MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEEIVEHIDAEDIFAKLEVAKPG
FINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFGGPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVVSDVHLG
DWGTQMGMLIEEIKLQSPQLVYFDENYTGEYPTESPVTVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVAL
WQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDTNKDGVPPLIVIKKDGGVMYG
TTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAERTKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLI
SQAKEYAKNRMPDENDDSIIDQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTVVRAKSILRKIFGDNYDI
KSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVNCPINNLDDESLKKARIALCM
ATVKAMTIASDLIGISIPERM
>Mature_581_residues
MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEEIVEHIDAEDIFAKLEVAKPG
FINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFGGPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVVSDVHLG
DWGTQMGMLIEEIKLQSPQLVYFDENYTGEYPTESPVTVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVAL
WQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDTNKDGVPPLIVIKKDGGVMYG
TTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAERTKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLI
SQAKEYAKNRMPDENDDSIIDQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTVVRAKSILRKIFGDNYDI
KSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVNCPINNLDDESLKKARIALCM
ATVKAMTIASDLIGISIPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=579, Percent_Identity=31.9516407599309, Blast_Score=290, Evalue=3e-78,
Organism=Homo sapiens, GI197100773, Length=582, Percent_Identity=26.2886597938144, Blast_Score=181, Evalue=2e-45,
Organism=Escherichia coli, GI1788184, Length=597, Percent_Identity=34.8408710217755, Blast_Score=342, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI71985061, Length=568, Percent_Identity=30.1056338028169, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71985068, Length=525, Percent_Identity=30.2857142857143, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17532153, Length=366, Percent_Identity=27.8688524590164, Blast_Score=129, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6321883, Length=558, Percent_Identity=27.7777777777778, Blast_Score=206, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6320548, Length=604, Percent_Identity=26.3245033112583, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI18859963, Length=605, Percent_Identity=30.2479338842975, Blast_Score=275, Evalue=5e-74,
Organism=Drosophila melanogaster, GI28571570, Length=478, Percent_Identity=25.1046025104602, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 65898; Mature: 65898

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCCCHHHHHH
IVEHIDAEDIFAKLEVAKPGFINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFG
HHHHCCHHHHHHHHEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECC
GPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVVSDVHLGDWGTQMGMLIEEIKLQSPQL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
VYFDENYTGEYPTESPVTVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVAL
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
WQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDT
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEC
NKDGVPPLIVIKKDGGVMYGTTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAER
CCCCCCCEEEEECCCCEEECCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHH
TKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLISQAKEYAKNRMPDENDDSII
HHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
DQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTVVRAKSILRKIFGDNYDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
KSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVN
HHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
CPINNLDDESLKKARIALCMATVKAMTIASDLIGISIPERM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCCCHHHHHH
IVEHIDAEDIFAKLEVAKPGFINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFG
HHHHCCHHHHHHHHEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECC
GPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVVSDVHLGDWGTQMGMLIEEIKLQSPQL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
VYFDENYTGEYPTESPVTVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVAL
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
WQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDT
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEC
NKDGVPPLIVIKKDGGVMYGTTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAER
CCCCCCCEEEEECCCCEEECCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHH
TKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLISQAKEYAKNRMPDENDDSII
HHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
DQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTVVRAKSILRKIFGDNYDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
KSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVN
HHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
CPINNLDDESLKKARIALCMATVKAMTIASDLIGISIPERM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA