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The map label for this gene is gpsA

Identifier: 134302235

GI number: 134302235

Start: 1239916

End: 1240914

Strand: Reverse

Name: gpsA

Synonym: FTW_1309

Alternate gene names: 134302235

Gene position: 1240914-1239916 (Counterclockwise)

Preceding gene: 134302236

Following gene: 134302227

Centisome position: 65.36

GC content: 36.04

Gene sequence:

>999_bases
ATGCAAAAAAATATACTTGTTTTAGGGGCAGGAGCTTGGGGTACGGCACTAGCATTACAGCTTGCTTATAGAGGACATAA
TGTCAGAATTAACTCATGGAAAGCTGAGCATAATGAACAAATGCTAAAGGATAATAACAATCATAAATACCTACCGAGTA
TAGAGAAATTTCCTTCTAGATTAAAAGCTATTCAAGATTGGCAAGCTAATATCATTGAGTTTGATAGTATATTAGTTGCA
ACTCCAAGCTCTGGTTTTAAGAATACTATTTTAGAGCTAAAAGAATGTATCTTACCGCAGCAAAACATTATTAGTGCAAC
AAAAGGTTTTTGTCATGATAGTTATGCGTTATTAAGTGAAATAGCTGAAGATATTTTGCCAACTACAAAATTTGCGTTAT
TAACAGGACCAAGCTTTGCTAAAGAGTTAGCTAATCAGCTCCCAACAGCTGTAGTAGTAGCCTCAAAAGATATTAATTAT
GCACGTTATGTCCAAGAGCTTTTCAGTAATGAGAATTTTAGATGCTACACAACAACTGATATCATCGGTGCTCAAGTTGG
CGGTGCTGTCAAAAATGTTCTAGCAATCACAGCTGGGATTGCTGCAGGTATGGAGTTTGGTGTTAATGCTCATGCCGCTC
TTATTACTCGTGGTCTAGCAGAGATAAAGAAACTTGGGCTTAAACTAGGTGCAAACTCAGAAACTTTTATTGGACTTAGC
TGTTTAGGGGATTTATTGTTGACATGTTCGGACAATCAGTCGCGCAATCGTAGATTTGGACTATATTTGGGGCAGGGTAT
GACTATACAACAAGCATTAAAAGAGGTAAATAATGTTGTTGAAGGCTATTTCACTGCAAAAGCTGTTTATAACCTTGCTA
AAAAACATAATGTTGAGATGCCTTTAGTATTTGCTACTTATAGAATTTTGTATGAAGCCGCTGATCCTAGAGATATCGTC
AAAGAACTTATGACTCGTCAGCTAAAAAATGAAAATTAA

Upstream 100 bases:

>100_bases
GATTTTATTGTGTCGATAAATAAAAGTTATATTAAAGAGGTGTTTACACTTTGGCAACTATAGAATATATTAGAACTAAA
AGAGTCGACAAATTTAGTTT

Downstream 100 bases:

>100_bases
TTAGCCACCTGCGACCTGTTTCGGTACATAATCTTTAAGATTAGTTTGTTGCATTTTCACTTTAGTATTAAAAGCATAAT
CACCGACCTTTACAAGAGGC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQKNILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHKYLPSIEKFPSRLKAIQDWQANIIEFDSILVA
TPSSGFKNTILELKECILPQQNIISATKGFCHDSYALLSEIAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINY
ARYVQELFSNENFRCYTTTDIIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGANSETFIGLS
CLGDLLLTCSDNQSRNRRFGLYLGQGMTIQQALKEVNNVVEGYFTAKAVYNLAKKHNVEMPLVFATYRILYEAADPRDIV
KELMTRQLKNEN

Sequences:

>Translated_332_residues
MQKNILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHKYLPSIEKFPSRLKAIQDWQANIIEFDSILVA
TPSSGFKNTILELKECILPQQNIISATKGFCHDSYALLSEIAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINY
ARYVQELFSNENFRCYTTTDIIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGANSETFIGLS
CLGDLLLTCSDNQSRNRRFGLYLGQGMTIQQALKEVNNVVEGYFTAKAVYNLAKKHNVEMPLVFATYRILYEAADPRDIV
KELMTRQLKNEN
>Mature_332_residues
MQKNILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHKYLPSIEKFPSRLKAIQDWQANIIEFDSILVA
TPSSGFKNTILELKECILPQQNIISATKGFCHDSYALLSEIAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINY
ARYVQELFSNENFRCYTTTDIIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGANSETFIGLS
CLGDLLLTCSDNQSRNRRFGLYLGQGMTIQQALKEVNNVVEGYFTAKAVYNLAKKHNVEMPLVFATYRILYEAADPRDIV
KELMTRQLKNEN

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=335, Percent_Identity=27.7611940298507, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI24307999, Length=347, Percent_Identity=27.0893371757925, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1790037, Length=334, Percent_Identity=43.7125748502994, Blast_Score=273, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI32564399, Length=344, Percent_Identity=27.0348837209302, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=354, Percent_Identity=26.5536723163842, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193210136, Length=354, Percent_Identity=26.5536723163842, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17507425, Length=341, Percent_Identity=23.7536656891496, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193210134, Length=232, Percent_Identity=28.8793103448276, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324513, Length=355, Percent_Identity=30.1408450704225, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320181, Length=341, Percent_Identity=28.4457478005865, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI22026922, Length=338, Percent_Identity=25.4437869822485, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17136204, Length=338, Percent_Identity=27.2189349112426, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17136200, Length=338, Percent_Identity=27.2189349112426, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17136202, Length=338, Percent_Identity=27.2189349112426, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_FRAT1 (Q14HX3)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_667003.1
- ProteinModelPortal:   Q14HX3
- SMR:   Q14HX3
- STRING:   Q14HX3
- GeneID:   4200296
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF0871
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   Q14HX3
- ProtClustDB:   PRK00094
- BioCyc:   FTUL393115:FTF0871-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36644; Mature: 36644

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 191-191 BINDING 108-108 BINDING 108-108 BINDING 140-140 BINDING 255-255 BINDING 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKNILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHKYLPSIEKFPSR
CCCCEEEEECCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHH
LKAIQDWQANIIEFDSILVATPSSGFKNTILELKECILPQQNIISATKGFCHDSYALLSE
HHHHHHHHCCCEEECEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHH
IAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINYARYVQELFSNENFRCYTTTD
HHHHHCCCCHHEEEECCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEHH
IIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGANSETFIGLS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHH
CLGDLLLTCSDNQSRNRRFGLYLGQGMTIQQALKEVNNVVEGYFTAKAVYNLAKKHNVEM
HHHHHHEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLVFATYRILYEAADPRDIVKELMTRQLKNEN
CHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQKNILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHKYLPSIEKFPSR
CCCCEEEEECCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHH
LKAIQDWQANIIEFDSILVATPSSGFKNTILELKECILPQQNIISATKGFCHDSYALLSE
HHHHHHHHCCCEEECEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHH
IAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINYARYVQELFSNENFRCYTTTD
HHHHHCCCCHHEEEECCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEHH
IIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGANSETFIGLS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHH
CLGDLLLTCSDNQSRNRRFGLYLGQGMTIQQALKEVNNVVEGYFTAKAVYNLAKKHNVEM
HHHHHHEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLVFATYRILYEAADPRDIVKELMTRQLKNEN
CHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA