Click here to switch to the map view.

The map label for this gene is dnaQ [H]

Identifier: 134301975

GI number: 134301975

Start: 946625

End: 947317

Strand: Reverse

Name: dnaQ [H]

Synonym: FTW_0993

Alternate gene names: 134301975

Gene position: 947317-946625 (Counterclockwise)

Preceding gene: 134301976

Following gene: 134301974

Centisome position: 49.9

GC content: 31.31

Gene sequence:

>693_bases
ATGTCACGACAAGTTTTTATAGATACTGAGACAACTGGCTTTGATTATAAGATTGGTAATAGAATTATTGAATTTGGTGC
AGTTGAAGTTATTGATAGAAGGATAACAGGTAATAATTTACATTTTTATTGTAATCCAAATTATGAAGTTGAAGCTGGAG
CTTTAGCTATTCATGGTCTTACAAATGAATTTCTAGCAGATAAACCTCTTTTTGAGGATAAAGTTGATGAGATGATTGAG
TTTTTAAGAGGTGCTGAAGTAATCATTCATAATGCAGCTTTTGATGTGCCATTTATAAATTGGGAACTTAGTCTCTTAAA
AAATAATAAATACGGAACATTAGAGCAAAATGTTGCTAAAATAGTAGATAGCCTTGATTTAGCTAGAAAAAAACATCCAT
TACAAAAAAATAATCTTGATGCTCTATGTAAAAGATATCAAATTAGGAATGATCATCGTACCTTTCACGGAGCATTATTA
GATAGTGAGCTGTTAGCGGATGTTTATCTAGCTATGACAGGTGGGCAGACTAATCTAAGTCTGCAAACAGCCAAAACTGT
GAGCAAAAATAGTATTGATATTGATGTCAATAAACTAAACTTACGTAATGCTGAAGATAGTATTAGCGATATTTCTGCAC
ACCATAGTTATCTTAGTAATTTGCTAAAACTAGAAGAAGATGCAAAATGGTAA

Upstream 100 bases:

>100_bases
AGGAAACCCAGAATTATCTTTCTATAAACTATACATTATATTTATAAGAATCTATTGTTATAATTAGTCATTAGTAATGA
TATATATACTATTTTTTAGA

Downstream 100 bases:

>100_bases
GAAAAATAATTTTTCCAGAAGCAAAAGAGCATGAGCTTATTTCGGCAGGTAAAGATTTTTTTGCTAGAGATTTACTTTTA
GAGAAAAATACTTATAAAGC

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYEVEAGALAIHGLTNEFLADKPLFEDKVDEMIE
FLRGAEVIIHNAAFDVPFINWELSLLKNNKYGTLEQNVAKIVDSLDLARKKHPLQKNNLDALCKRYQIRNDHRTFHGALL
DSELLADVYLAMTGGQTNLSLQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW

Sequences:

>Translated_230_residues
MSRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYEVEAGALAIHGLTNEFLADKPLFEDKVDEMIE
FLRGAEVIIHNAAFDVPFINWELSLLKNNKYGTLEQNVAKIVDSLDLARKKHPLQKNNLDALCKRYQIRNDHRTFHGALL
DSELLADVYLAMTGGQTNLSLQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW
>Mature_229_residues
SRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYEVEAGALAIHGLTNEFLADKPLFEDKVDEMIEF
LRGAEVIIHNAAFDVPFINWELSLLKNNKYGTLEQNVAKIVDSLDLARKKHPLQKNNLDALCKRYQIRNDHRTFHGALLD
SELLADVYLAMTGGQTNLSLQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=239, Percent_Identity=43.0962343096234, Blast_Score=207, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26109; Mature: 25978

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYEVEAGALAIHGL
CCCEEEEECCCCCCCCHHCCHHHHHHHHHHHHHEECCCCEEEEECCCCEEECCEEEEECC
TNEFLADKPLFEDKVDEMIEFLRGAEVIIHNAAFDVPFINWELSLLKNNKYGTLEQNVAK
CHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEEECCCCCCHHHHHHH
IVDSLDLARKKHPLQKNNLDALCKRYQIRNDHRTFHGALLDSELLADVYLAMTGGQTNLS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCEE
LQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW
EEHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYEVEAGALAIHGL
CCEEEEECCCCCCCCHHCCHHHHHHHHHHHHHEECCCCEEEEECCCCEEECCEEEEECC
TNEFLADKPLFEDKVDEMIEFLRGAEVIIHNAAFDVPFINWELSLLKNNKYGTLEQNVAK
CHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEEECCCCCCHHHHHHH
IVDSLDLARKKHPLQKNNLDALCKRYQIRNDHRTFHGALLDSELLADVYLAMTGGQTNLS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCEE
LQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW
EEHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]