BacMap

Definition	Francisella tularensis subsp. tularensis WY96-3418, complete genome.
Accession	NC_009257
Length	1,898,476

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The map label for this gene is fabG [H]

Identifier: 134301866

GI number: 134301866

Start: 830941

End: 831648

Strand: Reverse

Name: fabG [H]

Synonym: FTW_0857

Alternate gene names: 134301866

Gene position: 831648-830941 (Counterclockwise)

Preceding gene: 134301867

Following gene: 134301865

Centisome position: 43.81

GC content: 32.91

Gene sequence:

>708_bases
ATGTCTAATAGAATTGTTTTAATTACAGGTGCCACAAAAGGAATTGGATTAGCTACAAGCTTATATTTAAATAATCAAGG
ATGGCAAGTTATTGGAATAGCGAGATCATATATTGATAATTTCCCCGGAGAGTTGTTTTTATGTGACTTAGCTAATGAAG
AACAAACTGCCTCTACACTCATTCAAATAAATGAGATTCATGGATGTCCAGATGCAATTATTAATAATGTTGGAATAGCT
ATTCCAGAACCTTTGGGAAAAATTTCTATTTCAGCACTTAATGACGTCTATAATTTAAATGTTAGAAGTGCTGTACAAGT
ATCACAGTTTTTTATTGAAAAAATGAAACTAAAAGAACAATGCAAAATTGTTAATATTGCAAGTAGAGCTATCTTTGGAG
TTAAAAATCGTACAAGTTATTCCACTGCAAAATCTGCTTTGGTTGGATGTACTAAAACTTGGGCTCTAGAGCTTGCTAAG
TATGGAATATGTGTAAATGCTATAGCTCCGGGTCCAGTAGATACTGAATTATTTAGAAAAACTAGACCTATTGGTAGTAG
TGAAGAAAAAGAAGTTTTAGATTCTATTCCTATGATGCGTATAGGGAAGCCTGAAGAAATAGCTGCAACAATAGCTTTCT
TATTATCAAACGAAGCATCTTTTATCACAGGACAAGTCATTTGTGTTGACGGTGGTGGAAGTTTATAA

Upstream 100 bases:

>100_bases
CAGAGTCTGATTATGTCTACAAAGAGAATTGGTTCTCAGATCATGCACCATTAACTATTAATTATGATTATGAGGTTTAA
TCTACCAAGGAGCTCTTAAA

Downstream 100 bases:

>100_bases
CAATGTACTATATTTATGTATTCTCAGGTTTGCCAGGAGTAGGCAAAACAACTTTAGCTAAACAATTAGCTCAAGTTATA
CCTAATACGGCATACTTTAG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTLIQINEIHGCPDAIINNVGIA
IPEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQCKIVNIASRAIFGVKNRTSYSTAKSALVGCTKTWALELAK
YGICVNAIAPGPVDTELFRKTRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFITGQVICVDGGGSL

Sequences:

>Translated_235_residues
MSNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTLIQINEIHGCPDAIINNVGIA
IPEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQCKIVNIASRAIFGVKNRTSYSTAKSALVGCTKTWALELAK
YGICVNAIAPGPVDTELFRKTRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFITGQVICVDGGGSL
>Mature_234_residues
SNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTLIQINEIHGCPDAIINNVGIAI
PEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQCKIVNIASRAIFGVKNRTSYSTAKSALVGCTKTWALELAKY
GICVNAIAPGPVDTELFRKTRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFITGQVICVDGGGSL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=31.1203319502075, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=27.0161290322581, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=29.5081967213115, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=27.8008298755187, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI66933014, Length=143, Percent_Identity=37.7622377622378, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=27.2373540856031, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4503301, Length=189, Percent_Identity=30.6878306878307, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.1746031746032, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI59889578, Length=207, Percent_Identity=28.5024154589372, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=27.4590163934426, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=24.8995983935743, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=29.4736842105263, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=32.3529411764706, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=30.7377049180328, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=30.6451612903226, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=32.258064516129, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=28.1746031746032, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=30.8, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=26.4227642276423, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=29.6747967479675, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=26.7489711934156, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI2367365, Length=235, Percent_Identity=23.8297872340426, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=30.0546448087432, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789057, Length=199, Percent_Identity=25.6281407035176, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=26.2548262548263, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=31.7269076305221, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=279, Percent_Identity=31.5412186379928, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=28.6290322580645, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=31.1787072243346, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=28.3582089552239, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=29.2592592592593, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=29.1187739463602, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=28.3524904214559, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=28.7313432835821, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=29.4354838709677, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=29.277566539924, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=29.7619047619048, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=29.6577946768061, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=28.4, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=26.5151515151515, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=29.1044776119403, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=28.3524904214559, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=29.0909090909091, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=26.0377358490566, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=26.9662921348315, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=28.3018867924528, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.5873015873016, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=197, Percent_Identity=28.4263959390863, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=251, Percent_Identity=25.8964143426295, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=25.4032258064516, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=185, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=30.8, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=29.6747967479675, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.3149606299213, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=30.3149606299213, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=28.8617886178862, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=29.4820717131474, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=27.1255060728745, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648693, Length=235, Percent_Identity=26.3829787234043, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355889, Length=235, Percent_Identity=26.3829787234043, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25311; Mature: 25179

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTL
CCCCEEEEECCCCCCCEEEEEEECCCCCEEEEEEHHHHHCCCCCEEEEECCCCHHHHHHH
IQINEIHGCPDAIINNVGIAIPEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQ
EEEECCCCCHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
CKIVNIASRAIFGVKNRTSYSTAKSALVGCTKTWALELAKYGICVNAIAPGPVDTELFRK
HHEEEEHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCHHHHHH
TRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFITGQVICVDGGGSL
HCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
>Mature Secondary Structure 
SNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTL
CCCEEEEECCCCCCCEEEEEEECCCCCEEEEEEHHHHHCCCCCEEEEECCCCHHHHHHH
IQINEIHGCPDAIINNVGIAIPEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQ
EEEECCCCCHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
CKIVNIASRAIFGVKNRTSYSTAKSALVGCTKTWALELAKYGICVNAIAPGPVDTELFRK
HHEEEEHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCHHHHHH
TRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFITGQVICVDGGGSL
HCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]