Click here to switch to the map view.

The map label for this gene is add [H]

Identifier: 134301850

GI number: 134301850

Start: 811663

End: 812607

Strand: Reverse

Name: add [H]

Synonym: FTW_0833

Alternate gene names: 134301850

Gene position: 812607-811663 (Counterclockwise)

Preceding gene: 134301851

Following gene: 134301848

Centisome position: 42.8

GC content: 28.25

Gene sequence:

>945_bases
ATGCTCAATGAAAAACTTCTATTAAGACCTAAAGCTGAACTTCATCTACATATAGAAGGTACTATAGAACCAGAAATGAT
GTTTCAATTAGCTCAAAGAAATAATGTTAAGCTTAAATATAATTCAATAAAAGAGATTAGCAAAGCTTATGTATTTAATA
ATCTTCAAAATTTTTTAGATTTATATTATCAAGGTGTGTCTGTATTAATTACAGAACAAGATTTTTATGACATAACTTAT
TCTTATTTGGTGAAAGCACATAAAGATAATGTAACACATACAGAAATATTTATAGATCCTCAAGTACACTCTGAGCGAGG
AATATCTTTATCAGTAATATTTAATGGAGTTACTCAAGCTATCAGAGAAGCTGAAAAAAACTTTGGTATAAAAACTAGTG
TAATAGTGTGTTTTTTACTTCATTTATCACAAGATCATGCTCTAAGATATTTTGAGAAATTAATGGATTTTCATGATAGG
TTTATAGGTATAGGTTTAGATGGCTATGAGTTCGGAAATCCACCTTCTAAGTTTAAAAAACTCTTCGAAATAGCCAAAAA
AGAAGGATTATATTTAACTACACATGTTTCAGAACCTGTTGAGTATATTTGGGAAGCTATAGATGTTCTAGGTGTTAATA
GAATAGATCATGGTAACTCGATTCTAGAAGATGAAACATTAATTCAAAGAGTTATAAAAGATAACATACCTTTGACAATG
TGTCCATTATCTGATAAGTTCTTAAAGACTAATAGCAATTTATCTAGCCATCCTGTAGGTATACTTCTTGAGAAAGGTGT
TAAAGTCACTATTAACTCAGATGATCCAGCATATTTTTCAGGTTATATTAATGAAAACTATAGGCAAATATCTCAAGCTC
TAAAATTATCAGAAGATCAAATTATTAAGCTTATTAACAATAGTTTAGAGTCTAAGTTTATTTGA

Upstream 100 bases:

>100_bases
GATTGTTTGTTTATGGTACAATCCGCTATGAAATTGTTTAAAAGTTCTTCTCTTTTTATACGATAATATAAGCTATTGGT
ATTAGTTACTTTACAAAAAT

Downstream 100 bases:

>100_bases
CAATGACTTTATTGAATATATCTGATTAGAAAACAGAATTAATAAGAAATGACTAAAAATCAAGTAAATATATAACAAAG
ATCTCTATCTTACTCTTAGA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLNEKLLLRPKAELHLHIEGTIEPEMMFQLAQRNNVKLKYNSIKEISKAYVFNNLQNFLDLYYQGVSVLITEQDFYDITY
SYLVKAHKDNVTHTEIFIDPQVHSERGISLSVIFNGVTQAIREAEKNFGIKTSVIVCFLLHLSQDHALRYFEKLMDFHDR
FIGIGLDGYEFGNPPSKFKKLFEIAKKEGLYLTTHVSEPVEYIWEAIDVLGVNRIDHGNSILEDETLIQRVIKDNIPLTM
CPLSDKFLKTNSNLSSHPVGILLEKGVKVTINSDDPAYFSGYINENYRQISQALKLSEDQIIKLINNSLESKFI

Sequences:

>Translated_314_residues
MLNEKLLLRPKAELHLHIEGTIEPEMMFQLAQRNNVKLKYNSIKEISKAYVFNNLQNFLDLYYQGVSVLITEQDFYDITY
SYLVKAHKDNVTHTEIFIDPQVHSERGISLSVIFNGVTQAIREAEKNFGIKTSVIVCFLLHLSQDHALRYFEKLMDFHDR
FIGIGLDGYEFGNPPSKFKKLFEIAKKEGLYLTTHVSEPVEYIWEAIDVLGVNRIDHGNSILEDETLIQRVIKDNIPLTM
CPLSDKFLKTNSNLSSHPVGILLEKGVKVTINSDDPAYFSGYINENYRQISQALKLSEDQIIKLINNSLESKFI
>Mature_314_residues
MLNEKLLLRPKAELHLHIEGTIEPEMMFQLAQRNNVKLKYNSIKEISKAYVFNNLQNFLDLYYQGVSVLITEQDFYDITY
SYLVKAHKDNVTHTEIFIDPQVHSERGISLSVIFNGVTQAIREAEKNFGIKTSVIVCFLLHLSQDHALRYFEKLMDFHDR
FIGIGLDGYEFGNPPSKFKKLFEIAKKEGLYLTTHVSEPVEYIWEAIDVLGVNRIDHGNSILEDETLIQRVIKDNIPLTM
CPLSDKFLKTNSNLSSHPVGILLEKGVKVTINSDDPAYFSGYINENYRQISQALKLSEDQIIKLINNSLESKFI

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=332, Percent_Identity=23.1927710843373, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI1787910, Length=312, Percent_Identity=26.9230769230769, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI32565969, Length=323, Percent_Identity=22.9102167182663, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538512, Length=323, Percent_Identity=22.9102167182663, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324188, Length=293, Percent_Identity=40.9556313993174, Blast_Score=226, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36137; Mature: 36137

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEKLLLRPKAELHLHIEGTIEPEMMFQLAQRNNVKLKYNSIKEISKAYVFNNLQNFLD
CCCCCEEECCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHH
LYYQGVSVLITEQDFYDITYSYLVKAHKDNVTHTEIFIDPQVHSERGISLSVIFNGVTQA
HHHCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHH
IREAEKNFGIKTSVIVCFLLHLSQDHALRYFEKLMDFHDRFIGIGLDGYEFGNPPSKFKK
HHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHH
LFEIAKKEGLYLTTHVSEPVEYIWEAIDVLGVNRIDHGNSILEDETLIQRVIKDNIPLTM
HHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
CPLSDKFLKTNSNLSSHPVGILLEKGVKVTINSDDPAYFSGYINENYRQISQALKLSEDQ
CCCCCHHHHCCCCCCCCCCEEEEECCEEEEECCCCCCEEECCCCHHHHHHHHHHHCCHHH
IIKLINNSLESKFI
HHHHHHHHHHHCCC
>Mature Secondary Structure
MLNEKLLLRPKAELHLHIEGTIEPEMMFQLAQRNNVKLKYNSIKEISKAYVFNNLQNFLD
CCCCCEEECCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHH
LYYQGVSVLITEQDFYDITYSYLVKAHKDNVTHTEIFIDPQVHSERGISLSVIFNGVTQA
HHHCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHH
IREAEKNFGIKTSVIVCFLLHLSQDHALRYFEKLMDFHDRFIGIGLDGYEFGNPPSKFKK
HHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHH
LFEIAKKEGLYLTTHVSEPVEYIWEAIDVLGVNRIDHGNSILEDETLIQRVIKDNIPLTM
HHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
CPLSDKFLKTNSNLSSHPVGILLEKGVKVTINSDDPAYFSGYINENYRQISQALKLSEDQ
CCCCCHHHHCCCCCCCCCCEEEEECCEEEEECCCCCCEEECCCCHHHHHHHHHHHCCHHH
IIKLINNSLESKFI
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA