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The map label for this gene is trpS [H]

Identifier: 134301829

GI number: 134301829

Start: 780768

End: 781772

Strand: Reverse

Name: trpS [H]

Synonym: FTW_0805

Alternate gene names: 134301829

Gene position: 781772-780768 (Counterclockwise)

Preceding gene: 134301830

Following gene: 134301828

Centisome position: 41.18

GC content: 34.83

Gene sequence:

>1005_bases
ATGTCACAAAAAATAACTTTAACTGGTGTCACTCCATCAGGGACGCCACATTTAGGTAACTATATCGGCGCTATTAAACC
AGCAATCGAAATGATTAAAAATGATCAATATAAATGTATGTACTTTATTGCTGATCAACATTCGTTAATCAAACTTTGGG
ATAAAAAATTACGCCAGCAATACATTTATGAAATAGCTGCATCTTGGTTAGCACTTGGACTTGACCCTGACAAAGCTTAT
TTCTATCGTCAGTCAGATATTCCTGAGATAATGGAATTAACGTGGATTATTAGTACAACTACTGCTAAAGGATTACTTAA
CCGAGCTCACGCTTACAAAGCCTTAGTTGATCAGAATCTTCAAGAGGAGAATGCTGATCCTGATAAAGGTATAACTATGG
GACTATTTAACTACCCAGTACTTATGGCTGCAGATATTCTTATATTCGATGCGGACTTAGTTCCTGTTGGTAAGGATCAA
ATTCAACATATAGAAATAGCTCGAGATATCGCTAACCGTTTCAACCATATTTACCAAAAACCAGTTCTCAAGGCTCCTCA
AGCTCTGACAAGTGAAGATAGTCAAACTATACTTGGTTTAGATGGTCGCAAGATGTCAAAAAGCTACGATAATACTATAG
CCATTTTCTCAACGGAGAAAAAACTTAGAAAACAAGTAATGAAAATTATTACAAATTCTCAAATGCCTGAAGAGAAAAAA
GATCCAAATAACTGTACTATTTTCGCCATATACAAAAGTATTGCAAGCCAAACAGAGATAGCAGCCTTAGAGGAAAAATA
CTTGGCAGGTGGACTTGGTTGGGGAGATGCCAAACAAATACTTTTTGAAAAAATAAACGAATATCTCAGAGATGCTAGAG
AAAAATATGACTATTATATAAATAATCCTAAAATTGTCGATGATATTCTTAACCAAGGAGCTGTGAAAGTACGTCCTTTG
GCAAAAGATAAACTCAAAGAAGTTAAAGACATTATAGGAATGTAA

Upstream 100 bases:

>100_bases
AAAAATTCACGATAAATTCTCTTATTTTGATAGCCCTTATATGTTAAAATTTACATTGTTTTAAAATGTATTTAAATATT
TTACAATCAGTGGGATAAAA

Downstream 100 bases:

>100_bases
AATGCAGAAGTTAGATAATATAATTATTGCTAACTACAGCATTCATTCTTTAGCGCTTATATGCTGGGCAAAGCAAAATT
TATCGGGTAACTTCTGTATC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSQKITLTGVTPSGTPHLGNYIGAIKPAIEMIKNDQYKCMYFIADQHSLIKLWDKKLRQQYIYEIAASWLALGLDPDKAY
FYRQSDIPEIMELTWIISTTTAKGLLNRAHAYKALVDQNLQEENADPDKGITMGLFNYPVLMAADILIFDADLVPVGKDQ
IQHIEIARDIANRFNHIYQKPVLKAPQALTSEDSQTILGLDGRKMSKSYDNTIAIFSTEKKLRKQVMKIITNSQMPEEKK
DPNNCTIFAIYKSIASQTEIAALEEKYLAGGLGWGDAKQILFEKINEYLRDAREKYDYYINNPKIVDDILNQGAVKVRPL
AKDKLKEVKDIIGM

Sequences:

>Translated_334_residues
MSQKITLTGVTPSGTPHLGNYIGAIKPAIEMIKNDQYKCMYFIADQHSLIKLWDKKLRQQYIYEIAASWLALGLDPDKAY
FYRQSDIPEIMELTWIISTTTAKGLLNRAHAYKALVDQNLQEENADPDKGITMGLFNYPVLMAADILIFDADLVPVGKDQ
IQHIEIARDIANRFNHIYQKPVLKAPQALTSEDSQTILGLDGRKMSKSYDNTIAIFSTEKKLRKQVMKIITNSQMPEEKK
DPNNCTIFAIYKSIASQTEIAALEEKYLAGGLGWGDAKQILFEKINEYLRDAREKYDYYINNPKIVDDILNQGAVKVRPL
AKDKLKEVKDIIGM
>Mature_333_residues
SQKITLTGVTPSGTPHLGNYIGAIKPAIEMIKNDQYKCMYFIADQHSLIKLWDKKLRQQYIYEIAASWLALGLDPDKAYF
YRQSDIPEIMELTWIISTTTAKGLLNRAHAYKALVDQNLQEENADPDKGITMGLFNYPVLMAADILIFDADLVPVGKDQI
QHIEIARDIANRFNHIYQKPVLKAPQALTSEDSQTILGLDGRKMSKSYDNTIAIFSTEKKLRKQVMKIITNSQMPEEKKD
PNNCTIFAIYKSIASQTEIAALEEKYLAGGLGWGDAKQILFEKINEYLRDAREKYDYYINNPKIVDDILNQGAVKVRPLA
KDKLKEVKDIIGM

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=342, Percent_Identity=28.9473684210526, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI41352700, Length=178, Percent_Identity=37.6404494382022, Blast_Score=124, Evalue=8e-29,
Organism=Escherichia coli, GI1789786, Length=344, Percent_Identity=32.2674418604651, Blast_Score=178, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI71982800, Length=343, Percent_Identity=31.1953352769679, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71982793, Length=343, Percent_Identity=31.1953352769679, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320474, Length=349, Percent_Identity=30.945558739255, Blast_Score=162, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24666151, Length=340, Percent_Identity=29.4117647058824, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37943; Mature: 37812

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKITLTGVTPSGTPHLGNYIGAIKPAIEMIKNDQYKCMYFIADQHSLIKLWDKKLRQQ
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHH
YIYEIAASWLALGLDPDKAYFYRQSDIPEIMELTWIISTTTAKGLLNRAHAYKALVDQNL
HHHHHHHHHHHHCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QEENADPDKGITMGLFNYPVLMAADILIFDADLVPVGKDQIQHIEIARDIANRFNHIYQK
HHCCCCCCCCCEEHHHHCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PVLKAPQALTSEDSQTILGLDGRKMSKSYDNTIAIFSTEKKLRKQVMKIITNSQMPEEKK
HHHHCCHHHCCCCCCEEEECCCCHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCC
DPNNCTIFAIYKSIASQTEIAALEEKYLAGGLGWGDAKQILFEKINEYLRDAREKYDYYI
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEE
NNPKIVDDILNQGAVKVRPLAKDKLKEVKDIIGM
CCCCHHHHHHCCCCEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQKITLTGVTPSGTPHLGNYIGAIKPAIEMIKNDQYKCMYFIADQHSLIKLWDKKLRQQ
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHH
YIYEIAASWLALGLDPDKAYFYRQSDIPEIMELTWIISTTTAKGLLNRAHAYKALVDQNL
HHHHHHHHHHHHCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QEENADPDKGITMGLFNYPVLMAADILIFDADLVPVGKDQIQHIEIARDIANRFNHIYQK
HHCCCCCCCCCEEHHHHCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PVLKAPQALTSEDSQTILGLDGRKMSKSYDNTIAIFSTEKKLRKQVMKIITNSQMPEEKK
HHHHCCHHHCCCCCCEEEECCCCHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCC
DPNNCTIFAIYKSIASQTEIAALEEKYLAGGLGWGDAKQILFEKINEYLRDAREKYDYYI
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEE
NNPKIVDDILNQGAVKVRPLAKDKLKEVKDIIGM
CCCCHHHHHHCCCCEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]