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The map label for this gene is yjcE [H]

Identifier: 134301827

GI number: 134301827

Start: 778733

End: 780031

Strand: Reverse

Name: yjcE [H]

Synonym: FTW_0803

Alternate gene names: 134301827

Gene position: 780031-778733 (Counterclockwise)

Preceding gene: 134301828

Following gene: 134301823

Centisome position: 41.09

GC content: 32.64

Gene sequence:

>1299_bases
ATGAGTGAATATTTTTTATTTAGTTTGCTAACTGTTGTAGCTGCATTAATGAGTTACATTAACACTAAGTTTCTAAAGTT
ACCCAAAGCAATAGGTTTAACAATTCTTTCAATAACCTTTTCGGCACTATGTGCCTCATTTTTGAGTCCATCAAATTTTT
TAGTAGTTGCTTTATCAAGTTTTGATTTCAAAAAAACTGTTCTTGATGGAATGTTATCTTTCTTATTATTTGCTAATGCG
TTGCATTTTAATATGATTGATCTAAAAAAAGAGTTAAAAGCTATATTTGGACTTGCAAGTATTGGTCTATTACTATCAGC
ACTTACAACTGCTATATTAATCTATGGTTTCTGTCTCCTAGTTGGTTTTGAAATTAGTTTAGGCTATTGCTTAGTTTTTG
GAGCGTTGATATCACCTACTGATCCAATTGCAGTAATTAGTACACTTGCTGGTAATAAATCTATACCCAAACATATCAAA
ACACGTGTAGTTGGTGAATCATTGTTTAATGATGCTACAGGAATTGTCCTTTTCGTAGTATTATCAAATATCGTTTTCTT
TGGTAGTGGTGGTGAATTTGGACAAGCTATTAATGGTCATGGTATTGAATATATTTGGATAATAGCTAAACAGATTGGCT
CAGAAGCTGGTGGTGGCATACTACTTGGTTATATATTTGCTAGAGTCGCACTTATATTTCTAAAGACTAATCAAGACTCT
GAAACTTCAATTTTTGTCACATTAGCCGTTGCAAGCATGGGATATGTAATCGCTCATAGCTTAAATGTATCAGGTCCTAT
TGCCATGGTAGTTGCTGGTTTATTCATCGGCAATAATCTTTCAGATCGTAAAAAAACATCTCCAGACCAAGTAGAAAAAC
TTGATAATTTTTGGATGGTTATCGATAATATGCTTAACTCTTTCCTATTTATACTTATAGGTCTAGAATTAACTAGTATA
CCATTTAATCATGGTGCTTTCTGGGTTGGTGCTGCTGGTATATTCATCGTAACATTTGCTAGATTAGTCAGTATATCAAT
ACCAATTACTGTAATAGATAAAAAGCTTACTCGAGCTTCAGCTAAAGATAATTTACTCGTAGCTTGGTCTGGAGTCAGAG
GCGGTATATCTTTAGCATTGGCATTATCATTACCTGATGAAGGTAATGTTATAGTTAGTATTACATATACCGTAGTTATA
TTATCAATACTTGCCCAAGGGTCTACCTTAAAAATTGTTCTAAATATAATTTACCCACATAACATAACTAAGAAAGCGGC
AAATACTGTAGATAACTAA

Upstream 100 bases:

>100_bases
TGATAAGTTAGATGATGGTTTCTTTACACAAAAAGATTTATTAGAAGAATTATCAAAGGCATGCAGCTGGGAGTATAGCT
GTGGCTTATAAGGAATTATT

Downstream 100 bases:

>100_bases
TAAATTATTCGTATTTGTGTTTATAGTAAGCATTACCTAAATATTTGTCTAGTTGTATTGCTTGTGGTGTTGAGCCTGTA
GGTCTACGTGGATTAACTCG

Product: monovalent cation:proton antiporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSSFDFKKTVLDGMLSFLLFANA
LHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLLVGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIK
TRVVGESLFNDATGIVLFVVLSNIVFFGSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDS
ETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMVIDNMLNSFLFILIGLELTSI
PFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRASAKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVI
LSILAQGSTLKIVLNIIYPHNITKKAANTVDN

Sequences:

>Translated_432_residues
MSEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSSFDFKKTVLDGMLSFLLFANA
LHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLLVGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIK
TRVVGESLFNDATGIVLFVVLSNIVFFGSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDS
ETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMVIDNMLNSFLFILIGLELTSI
PFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRASAKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVI
LSILAQGSTLKIVLNIIYPHNITKKAANTVDN
>Mature_431_residues
SEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSSFDFKKTVLDGMLSFLLFANAL
HFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLLVGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIKT
RVVGESLFNDATGIVLFVVLSNIVFFGSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDSE
TSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMVIDNMLNSFLFILIGLELTSIP
FNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRASAKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVIL
SILAQGSTLKIVLNIIYPHNITKKAANTVDN

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=352, Percent_Identity=23.8636363636364, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI15529998, Length=313, Percent_Identity=25.8785942492013, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790501, Length=445, Percent_Identity=25.3932584269663, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71980847, Length=355, Percent_Identity=24.2253521126761, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25150332, Length=323, Percent_Identity=25.077399380805, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71990924, Length=354, Percent_Identity=22.8813559322034, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71999819, Length=304, Percent_Identity=22.6973684210526, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71999821, Length=304, Percent_Identity=22.3684210526316, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71999817, Length=304, Percent_Identity=22.6973684210526, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71990932, Length=354, Percent_Identity=22.8813559322034, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992101, Length=362, Percent_Identity=22.6519337016575, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992107, Length=362, Percent_Identity=22.6519337016575, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=417, Percent_Identity=24.220623501199, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221473212, Length=347, Percent_Identity=26.5129682997118, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281364513, Length=347, Percent_Identity=26.5129682997118, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221473222, Length=347, Percent_Identity=26.5129682997118, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221473215, Length=347, Percent_Identity=26.5129682997118, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221510740, Length=391, Percent_Identity=24.0409207161125, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 46308; Mature: 46177

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
FDFKKTVLDGMLSFLLFANALHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIKTRVVGESLFNDATGIVLFVV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
LSNIVFFGSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDS
HHHHEEECCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHEEEEECCCCC
ETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMV
CCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IDNMLNSFLFILIGLELTSIPFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRAS
HHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCC
AKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVILSILAQGSTLKIVLNIIYPH
CCCCEEEEECCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCEEEEEEEEECCC
NITKKAANTVDN
CCHHHHHCCCCC
>Mature Secondary Structure 
SEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
FDFKKTVLDGMLSFLLFANALHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIKTRVVGESLFNDATGIVLFVV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
LSNIVFFGSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDS
HHHHEEECCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHEEEEECCCCC
ETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMV
CCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IDNMLNSFLFILIGLELTSIPFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRAS
HHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCC
AKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVILSILAQGSTLKIVLNIIYPH
CCCCEEEEECCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCEEEEEEEEECCC
NITKKAANTVDN
CCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]