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The map label for this gene is murQ [H]

Identifier: 134301821

GI number: 134301821

Start: 775538

End: 776422

Strand: Direct

Name: murQ [H]

Synonym: FTW_0797

Alternate gene names: 134301821

Gene position: 775538-776422 (Clockwise)

Preceding gene: 134301820

Following gene: 134301822

Centisome position: 40.85

GC content: 33.33

Gene sequence:

>885_bases
ATGAATATCTTAGAAAATATTAATACAGAAAAAAGAAATCCTAGAAGTTTAAATCTTGATTCCATGTCTATAGCTGAAGC
AGTTAGCTTAATGATAGATGAGGAGTATGGTGTAATTGAAGCACTAAAAGAACAGCATAGAAATATAACAGAGGTAATTT
TGGCAACATCTTATTCCCTAAGAAATGGTGGCAGGATTATATATATTGGTGCAGGTACAAGTGGTAGATTAGGTATATTA
GATGCCGTTGAATGTCCACCAACATTTAGTGTTGATTATAATACAATTGTAGGCTTGATAGCTGGTGGTGAAAAGGCATT
TATTCAAGCTCAAGAAGGAGCTGAAGATGATGCTAATTTTGGTAAAGAAGATTTGCAGAGCATAAATCTTACAGCTAAAG
ATATTGTAATAGGTATTGCTGCTAGTGGTAGGACTCCATATGTGATTGGTGCTCTTGAGTATGCTAACTCTATTGGTGCG
ACTACAGTTGCTATTAGTTGTACTAAACAAGCAAAAATATCAAAATATGCTAAATACTCTATAGAGGCAGTACCAGGACC
TGAAGTTTTAACAGGTTCAACAAGGCTAAAGGCTGGTACTACTCAAAAGCTGATTCTCAATATGATATCAACTCTTTCAA
TGGTCTCTGTCGGTAAAGTTTATCAAAATCTGATGGTAGATGTAAAACCTACTAACCAAAAGCTAATTGAACGCTCAAAG
AATATTATCTGTGAAGCTACGGGAGTAGATTATACAACTGCGGAGAAATTTTACTTAAAAGCCAATAAATCTGTCAAGGT
TGCAATAGTAATGATATTAAATAATTGTGATTATGAAAAAGCTTTGGCAATATTAAAGAACAATAATAATTTTATAAAGA
GCTAA

Upstream 100 bases:

>100_bases
ATGCTAAAGCTAAAGATGAAGAAGACAATCAACCAGCAGAACGTATATATTTAGACACTAAGTATCTTTATCCTTTGGGG
ATAGTCAAGGAAGTTAAATT

Downstream 100 bases:

>100_bases
GATGAGATTATTAATATTGTTTATAGCCGTTATGTTTAGTTTTGATAGCTATGCTACTATTTATGAAAAATATCAAAATG
GTGTGCCAGAATTTTCTAAT

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNILENINTEKRNPRSLNLDSMSIAEAVSLMIDEEYGVIEALKEQHRNITEVILATSYSLRNGGRIIYIGAGTSGRLGIL
DAVECPPTFSVDYNTIVGLIAGGEKAFIQAQEGAEDDANFGKEDLQSINLTAKDIVIGIAASGRTPYVIGALEYANSIGA
TTVAISCTKQAKISKYAKYSIEAVPGPEVLTGSTRLKAGTTQKLILNMISTLSMVSVGKVYQNLMVDVKPTNQKLIERSK
NIICEATGVDYTTAEKFYLKANKSVKVAIVMILNNCDYEKALAILKNNNNFIKS

Sequences:

>Translated_294_residues
MNILENINTEKRNPRSLNLDSMSIAEAVSLMIDEEYGVIEALKEQHRNITEVILATSYSLRNGGRIIYIGAGTSGRLGIL
DAVECPPTFSVDYNTIVGLIAGGEKAFIQAQEGAEDDANFGKEDLQSINLTAKDIVIGIAASGRTPYVIGALEYANSIGA
TTVAISCTKQAKISKYAKYSIEAVPGPEVLTGSTRLKAGTTQKLILNMISTLSMVSVGKVYQNLMVDVKPTNQKLIERSK
NIICEATGVDYTTAEKFYLKANKSVKVAIVMILNNCDYEKALAILKNNNNFIKS
>Mature_294_residues
MNILENINTEKRNPRSLNLDSMSIAEAVSLMIDEEYGVIEALKEQHRNITEVILATSYSLRNGGRIIYIGAGTSGRLGIL
DAVECPPTFSVDYNTIVGLIAGGEKAFIQAQEGAEDDANFGKEDLQSINLTAKDIVIGIAASGRTPYVIGALEYANSIGA
TTVAISCTKQAKISKYAKYSIEAVPGPEVLTGSTRLKAGTTQKLILNMISTLSMVSVGKVYQNLMVDVKPTNQKLIERSK
NIICEATGVDYTTAEKFYLKANKSVKVAIVMILNNCDYEKALAILKNNNNFIKS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=290, Percent_Identity=48.6206896551724, Blast_Score=261, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31828; Mature: 31828

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILENINTEKRNPRSLNLDSMSIAEAVSLMIDEEYGVIEALKEQHRNITEVILATSYSL
CCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHEECEEE
RNGGRIIYIGAGTSGRLGILDAVECPPTFSVDYNTIVGLIAGGEKAFIQAQEGAEDDANF
CCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHEEEEEECCCEEEEEECCCCCCCCCC
GKEDLQSINLTAKDIVIGIAASGRTPYVIGALEYANSIGATTVAISCTKQAKISKYAKYS
CHHHHHHCCCEEHHEEEEEECCCCCCEEEEEHHHHCCCCCEEEEEEECCHHHHHHHHHEE
IEAVPGPEVLTGSTRLKAGTTQKLILNMISTLSMVSVGKVYQNLMVDVKPTNQKLIERSK
EEECCCCCEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHCC
NIICEATGVDYTTAEKFYLKANKSVKVAIVMILNNCDYEKALAILKNNNNFIKS
CEEEEECCCCCCCCCEEEEEECCCEEEEEEEEECCCCHHHEEEEEECCCCCCCC
>Mature Secondary Structure
MNILENINTEKRNPRSLNLDSMSIAEAVSLMIDEEYGVIEALKEQHRNITEVILATSYSL
CCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHEECEEE
RNGGRIIYIGAGTSGRLGILDAVECPPTFSVDYNTIVGLIAGGEKAFIQAQEGAEDDANF
CCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHEEEEEECCCEEEEEECCCCCCCCCC
GKEDLQSINLTAKDIVIGIAASGRTPYVIGALEYANSIGATTVAISCTKQAKISKYAKYS
CHHHHHHCCCEEHHEEEEEECCCCCCEEEEEHHHHCCCCCEEEEEEECCHHHHHHHHHEE
IEAVPGPEVLTGSTRLKAGTTQKLILNMISTLSMVSVGKVYQNLMVDVKPTNQKLIERSK
EEECCCCCEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHCC
NIICEATGVDYTTAEKFYLKANKSVKVAIVMILNNCDYEKALAILKNNNNFIKS
CEEEEECCCCCCCCCEEEEEECCCEEEEEEEEECCCCHHHEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA