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The map label for this gene is visC [H]

Identifier: 134301764

GI number: 134301764

Start: 708408

End: 709643

Strand: Direct

Name: visC [H]

Synonym: FTW_0729

Alternate gene names: 134301764

Gene position: 708408-709643 (Clockwise)

Preceding gene: 134301763

Following gene: 134301765

Centisome position: 37.31

GC content: 33.74

Gene sequence:

>1236_bases
ATGAGCGTTAGAAATATTCAAAAAGATGCTGTGATTGTCGGTGGTGGTATGGTAGGCTTAAGCCTTGCTCTAGCATTGCA
CCAAAATGGTTTGCAGGTTGCGCTTGTTGAGGCAAAAGAGATTAATTATAAGTCTTTGAGTGCTGATAGAGTTGAAACTA
GAGTTAGTGCTATAAACCATACTTCGAAAAGTTTTTTACAACGATTAGGTGTGTGGCATAGTATCAAAAATAAGCGTATA
TCTCCATATTATCAAATGAGAGTTTGGGATGATATTCCTAGTGAGAGTATAAATATTACAGCTGAAGAAATAGCTGAGCA
TAGTTTAGGCTGTATTGTTGAAAATGATGTAATAGTTGAAGCGCTACTAGAGAAGATCAGAGATACAGGTATCGAGATCT
TTGCTAATCAAAAAATACATAAAATTCAAAGAAATGGTAATACTGAAAAGCTCTTTCTACAGGCAGTCATTCCGGACTCT
TGCTCTGATGGTTCTAGTCAGAATAGTGATGACAAGTATTTATCAATTGAAACTAGTCTAATAATTGGTGCAGATGGTGC
TAACTCTTTTATTCGCGACTATTTTAATTTTGAAACCAAAGTTAAACCATATAAACATACTGCAATAGTTGCAACAATTA
AGCTTGAAAGAAATCACCTGCAAACAGCATATCAACGTTTTTATGATAAAGGTGTATTGGCATTTTTACCCTTAGAAAAT
TCAAACAAAGCTTCAATAGTTTGGTCTGTAAAGAGTGATTATGCTAATTTTCTGATGAGTTTAACAGATGAGAAATTTGA
GCTAGAACTTACTAAGGCAATTGATAATAGTTTTGGTAGTCTTAATTTACTATCAAAAAGATTTAGTTTTGAGCTAATAG
AGCGTCATGCTAAAAGTTATATACAAAATAATGTAGTATTGGTAGGTGATGCAGCTCATACAATTCACCCATTAGCAGGG
CAAGGGGTAAATATAGGTTTTAAAGATGCTATTGCATTGACTGAAATTTTGACTGAGGCTTTTACAAAAGGTCGCTTGAT
TGGTCATATTTCAACATTAGATAAATATCAGCGTGAGCGTAAGCTTGATAATACTAAGATGCTAGCTTTGATGAAGACAT
TTAAAGAAGTCTTTGCTAGTGATAACCAATATCTCAAAAACGCGCGCAGGGCAGGATTTGAGTTTGTTGATAAAAATAGA
ATTGTTAAAAGTATAGTTGTGAAGCAAGCTTTATAA

Upstream 100 bases:

>100_bases
CATCTGTTACAAAGAAGTAAGTTAGCTAAAAAAGTTTTATCAAGAGTTATGATGGGCAAGCTTAGCAAAGGTTCAACTCT
GATGAGAAAGGTGGTCGAGG

Downstream 100 bases:

>100_bases
TCTCAAGAGAAAGGAAGCAGTATGGAAAACGAAATATTAGACATAAAAGAGCTATTCTTAGAATTTGATAAGCATGATGG
TTTAGAAGAGATTGTTAAAA

Product: UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSVRNIQKDAVIVGGGMVGLSLALALHQNGLQVALVEAKEINYKSLSADRVETRVSAINHTSKSFLQRLGVWHSIKNKRI
SPYYQMRVWDDIPSESINITAEEIAEHSLGCIVENDVIVEALLEKIRDTGIEIFANQKIHKIQRNGNTEKLFLQAVIPDS
CSDGSSQNSDDKYLSIETSLIIGADGANSFIRDYFNFETKVKPYKHTAIVATIKLERNHLQTAYQRFYDKGVLAFLPLEN
SNKASIVWSVKSDYANFLMSLTDEKFELELTKAIDNSFGSLNLLSKRFSFELIERHAKSYIQNNVVLVGDAAHTIHPLAG
QGVNIGFKDAIALTEILTEAFTKGRLIGHISTLDKYQRERKLDNTKMLALMKTFKEVFASDNQYLKNARRAGFEFVDKNR
IVKSIVVKQAL

Sequences:

>Translated_411_residues
MSVRNIQKDAVIVGGGMVGLSLALALHQNGLQVALVEAKEINYKSLSADRVETRVSAINHTSKSFLQRLGVWHSIKNKRI
SPYYQMRVWDDIPSESINITAEEIAEHSLGCIVENDVIVEALLEKIRDTGIEIFANQKIHKIQRNGNTEKLFLQAVIPDS
CSDGSSQNSDDKYLSIETSLIIGADGANSFIRDYFNFETKVKPYKHTAIVATIKLERNHLQTAYQRFYDKGVLAFLPLEN
SNKASIVWSVKSDYANFLMSLTDEKFELELTKAIDNSFGSLNLLSKRFSFELIERHAKSYIQNNVVLVGDAAHTIHPLAG
QGVNIGFKDAIALTEILTEAFTKGRLIGHISTLDKYQRERKLDNTKMLALMKTFKEVFASDNQYLKNARRAGFEFVDKNR
IVKSIVVKQAL
>Mature_410_residues
SVRNIQKDAVIVGGGMVGLSLALALHQNGLQVALVEAKEINYKSLSADRVETRVSAINHTSKSFLQRLGVWHSIKNKRIS
PYYQMRVWDDIPSESINITAEEIAEHSLGCIVENDVIVEALLEKIRDTGIEIFANQKIHKIQRNGNTEKLFLQAVIPDSC
SDGSSQNSDDKYLSIETSLIIGADGANSFIRDYFNFETKVKPYKHTAIVATIKLERNHLQTAYQRFYDKGVLAFLPLENS
NKASIVWSVKSDYANFLMSLTDEKFELELTKAIDNSFGSLNLLSKRFSFELIERHAKSYIQNNVVLVGDAAHTIHPLAGQ
GVNIGFKDAIALTEILTEAFTKGRLIGHISTLDKYQRERKLDNTKMLALMKTFKEVFASDNQYLKNARRAGFEFVDKNRI
VKSIVVKQAL

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=414, Percent_Identity=29.4685990338164, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI32967307, Length=344, Percent_Identity=30.5232558139535, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789273, Length=404, Percent_Identity=37.8712871287129, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1786883, Length=408, Percent_Identity=31.1274509803922, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789274, Length=405, Percent_Identity=27.1604938271605, Blast_Score=155, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI25146631, Length=448, Percent_Identity=28.3482142857143, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321694, Length=462, Percent_Identity=25.3246753246753, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19920760, Length=435, Percent_Identity=28.735632183908, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 46233; Mature: 46102

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRNIQKDAVIVGGGMVGLSLALALHQNGLQVALVEAKEINYKSLSADRVETRVSAINH
CCCCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
TSKSFLQRLGVWHSIKNKRISPYYQMRVWDDIPSESINITAEEIAEHSLGCIVENDVIVE
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEHHHHHHHHCCEEEECHHHHH
ALLEKIRDTGIEIFANQKIHKIQRNGNTEKLFLQAVIPDSCSDGSSQNSDDKYLSIETSL
HHHHHHHHCCEEEEECCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEE
IIGADGANSFIRDYFNFETKVKPYKHTAIVATIKLERNHLQTAYQRFYDKGVLAFLPLEN
EEECCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHCCCCEEEEECCC
SNKASIVWSVKSDYANFLMSLTDEKFELELTKAIDNSFGSLNLLSKRFSFELIERHAKSY
CCCEEEEEEEHHHHHHHHHHHCCCHHEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IQNNVVLVGDAAHTIHPLAGQGVNIGFKDAIALTEILTEAFTKGRLIGHISTLDKYQRER
HHCCEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
KLDNTKMLALMKTFKEVFASDNQYLKNARRAGFEFVDKNRIVKSIVVKQAL
HCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVRNIQKDAVIVGGGMVGLSLALALHQNGLQVALVEAKEINYKSLSADRVETRVSAINH
CCCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
TSKSFLQRLGVWHSIKNKRISPYYQMRVWDDIPSESINITAEEIAEHSLGCIVENDVIVE
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEHHHHHHHHCCEEEECHHHHH
ALLEKIRDTGIEIFANQKIHKIQRNGNTEKLFLQAVIPDSCSDGSSQNSDDKYLSIETSL
HHHHHHHHCCEEEEECCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEE
IIGADGANSFIRDYFNFETKVKPYKHTAIVATIKLERNHLQTAYQRFYDKGVLAFLPLEN
EEECCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHCCCCEEEEECCC
SNKASIVWSVKSDYANFLMSLTDEKFELELTKAIDNSFGSLNLLSKRFSFELIERHAKSY
CCCEEEEEEEHHHHHHHHHHHCCCHHEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IQNNVVLVGDAAHTIHPLAGQGVNIGFKDAIALTEILTEAFTKGRLIGHISTLDKYQRER
HHCCEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
KLDNTKMLALMKTFKEVFASDNQYLKNARRAGFEFVDKNRIVKSIVVKQAL
HCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]