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The map label for this gene is aaeR [H]

Identifier: 134301634

GI number: 134301634

Start: 568526

End: 569422

Strand: Reverse

Name: aaeR [H]

Synonym: FTW_0573

Alternate gene names: 134301634

Gene position: 569422-568526 (Counterclockwise)

Preceding gene: 134301637

Following gene: 134301630

Centisome position: 29.99

GC content: 27.87

Gene sequence:

>897_bases
ATGGGACATCTTGAAAGATTAAAGATATTTATAAAAGCAGCACATTTAAAAAGCTTTAGTAAGGCTGCAAAAGCTATAGG
CATATCTCCACCAGTAGTATCAAAACAAATACAAATCTTAGAAACAAAATATAGAAAATCACTATTTAATCGTAATACTA
GGACTGTACACTTGACAGAATATGGAAAACTACTTTATGAAAAAGCTAGTTTAATACTAAACGAATTAGAAGCCACAAAA
GAAAAAATTTTTGCCGAAGATATCCTAATAGATAGCGAATTAAAGATTTCTGCACCAAATTCATTTGGTATTAAATATCT
TTGCAATATATTTTCTAAATTTGCTATTGATTATCCAAAATATAAACTAAATATCAACTTATCAGATAGTTATATAAACA
TTATTGATGAAGATTTCGATTTAGTTATAAGAATTGGTGCTCTAGATGACTCAAATTTAATTACTAAAAAACTTATGCCG
ATGCCTAGTTTATTATGCGCAAGTGAACAATATTTAAAAAATTATGGCATACCTAAAACAATAAAAGATTTAGAGAATCA
TCTATTTATCCAATATAACAATCACAGCTCATCAAATCGCATAATCCTAGAATCCGTCAATAAAACTGAGATAATAAATG
TAAGACAAAGAATCGTAACTAATAGTGCTGGAATGATGCTCCAGAGTTGTTTAGATGGCTTAGGCATAGCAAAGTTACCA
TTATTTGAAATTATCGATAAACTTCACGATAAAAAGCTAGTTCATCTATTACCTAATACCAGAAATCCTATAGAAAAAAA
TCTCTATTTAATAAGTTCAAGAGATAAATACAGATTAAAGAAAGTTAGGTTACTAAGCGCTTATATAGAGAAAAATTTGC
CACAGATTGAATTATAA

Upstream 100 bases:

>100_bases
TAACTTTCTCCTAGAAGTCATTTTAATAAGCTAATGATATCGAATTTTTTTATGAGATAATTAACAAATATAGAAAAATA
TAATTTTCAATATAGAAATA

Downstream 100 bases:

>100_bases
AAGAATATAGATATTACTCAAAGAATTTTTTAGCGTAATCTTTAACATTGTCAAACCATGTTTTACTCTTTGGAGCATGC
TTACTTTGATAATCTTCACC

Product: transcriptional regulator, LysR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MGHLERLKIFIKAAHLKSFSKAAKAIGISPPVVSKQIQILETKYRKSLFNRNTRTVHLTEYGKLLYEKASLILNELEATK
EKIFAEDILIDSELKISAPNSFGIKYLCNIFSKFAIDYPKYKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITKKLMP
MPSLLCASEQYLKNYGIPKTIKDLENHLFIQYNNHSSSNRIILESVNKTEIINVRQRIVTNSAGMMLQSCLDGLGIAKLP
LFEIIDKLHDKKLVHLLPNTRNPIEKNLYLISSRDKYRLKKVRLLSAYIEKNLPQIEL

Sequences:

>Translated_298_residues
MGHLERLKIFIKAAHLKSFSKAAKAIGISPPVVSKQIQILETKYRKSLFNRNTRTVHLTEYGKLLYEKASLILNELEATK
EKIFAEDILIDSELKISAPNSFGIKYLCNIFSKFAIDYPKYKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITKKLMP
MPSLLCASEQYLKNYGIPKTIKDLENHLFIQYNNHSSSNRIILESVNKTEIINVRQRIVTNSAGMMLQSCLDGLGIAKLP
LFEIIDKLHDKKLVHLLPNTRNPIEKNLYLISSRDKYRLKKVRLLSAYIEKNLPQIEL
>Mature_297_residues
GHLERLKIFIKAAHLKSFSKAAKAIGISPPVVSKQIQILETKYRKSLFNRNTRTVHLTEYGKLLYEKASLILNELEATKE
KIFAEDILIDSELKISAPNSFGIKYLCNIFSKFAIDYPKYKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITKKLMPM
PSLLCASEQYLKNYGIPKTIKDLENHLFIQYNNHSSSNRIILESVNKTEIINVRQRIVTNSAGMMLQSCLDGLGIAKLPL
FEIIDKLHDKKLVHLLPNTRNPIEKNLYLISSRDKYRLKKVRLLSAYIEKNLPQIEL

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=280, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI145693193, Length=282, Percent_Identity=30.8510638297872, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=28.719723183391, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87081978, Length=304, Percent_Identity=28.6184210526316, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=27.0547945205479, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787128, Length=243, Percent_Identity=28.8065843621399, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787589, Length=254, Percent_Identity=20.4724409448819, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790783, Length=283, Percent_Identity=25.7950530035336, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=284, Percent_Identity=26.7605633802817, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789173, Length=242, Percent_Identity=28.9256198347107, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=32.4786324786325, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786448, Length=235, Percent_Identity=27.2340425531915, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=143, Percent_Identity=28.6713286713287, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34209; Mature: 34077

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHLERLKIFIKAAHLKSFSKAAKAIGISPPVVSKQIQILETKYRKSLFNRNTRTVHLTE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
YGKLLYEKASLILNELEATKEKIFAEDILIDSELKISAPNSFGIKYLCNIFSKFAIDYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCHHHHHHHHHHHCCCCCC
YKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITKKLMPMPSLLCASEQYLKNYGIPKT
EEEEEEECCCEEEEECCCCEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHH
IKDLENHLFIQYNNHSSSNRIILESVNKTEIINVRQRIVTNSAGMMLQSCLDGLGIAKLP
HHHHHCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
LFEIIDKLHDKKLVHLLPNTRNPIEKNLYLISSRDKYRLKKVRLLSAYIEKNLPQIEL
HHHHHHHHCCCCEEEECCCCCCCHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GHLERLKIFIKAAHLKSFSKAAKAIGISPPVVSKQIQILETKYRKSLFNRNTRTVHLTE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
YGKLLYEKASLILNELEATKEKIFAEDILIDSELKISAPNSFGIKYLCNIFSKFAIDYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCHHHHHHHHHHHCCCCCC
YKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITKKLMPMPSLLCASEQYLKNYGIPKT
EEEEEEECCCEEEEECCCCEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHH
IKDLENHLFIQYNNHSSSNRIILESVNKTEIINVRQRIVTNSAGMMLQSCLDGLGIAKLP
HHHHHCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
LFEIIDKLHDKKLVHLLPNTRNPIEKNLYLISSRDKYRLKKVRLLSAYIEKNLPQIEL
HHHHHHHHCCCCEEEECCCCCCCHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]