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The map label for this gene is mlaA [H]

Identifier: 134301413

GI number: 134301413

Start: 310178

End: 311278

Strand: Direct

Name: mlaA [H]

Synonym: FTW_0311

Alternate gene names: 134301413

Gene position: 310178-311278 (Clockwise)

Preceding gene: 134301408

Following gene: 134301415

Centisome position: 16.34

GC content: 37.06

Gene sequence:

>1101_bases
ATGAAACTAAATGCTAAGTCTACTTTGCTATTATCACTGTTAGGTGTGACTTTGAGTAGCTGCTCAAGTTTGAAAGCTAC
AAAAGATAATCGCGATCCTTTTGAGAGTTACAATAGAAAAATGTATGCTTTTAATGATAAGGCTTATGAAACTTTAACTC
CAGCTGCTAATTCGTATGAAAAAGTTGTTCCAGATACTTTAAAGAGCGGTATTTTTAATATTTTCCAAAACTTGGCTGAG
CCTGCTAGAGTTGCAAATGATATGTTCCAAGGTGAATGGGATTATGCTGGGGATGATGGTTTTAGATTCTTGACAAATAC
TACTTTAGGTTTGGCAGGTTACTTTGATGTCGCGGATAGTTGGTTTAACAAACCTATGAGATATCATCAAAGTTTTGCAG
TTACTCTTCATAAATGGGGTGTGTATAAGGATAATGAAGCCTCTCCTTATGTGGTATGGCCGTTAATTGGCCCAGGTACA
TTAGAGGATATTACTACAGGTGTTGATGCGTTGTTTAATCCATTAACTTATATATTCTTCTTTGCTCCAGTTGGTTCGGC
AATATCTTGGGGAGTAAGTGTTGGTACGACAGGTGCATATTATGTTAACCAAGGAGTATCATATCTACCATCATATTCAA
ATCTTAAAGAAGTTTCTATTGATCCTTACATAGCGATGAGAAATGCTTATTTACAAAATTATGACTATGGTATGGCTAAA
GTATTAAAACAACAGTTAAGCAAAGATGATGCAACTATTCAGACCGATCAAGCTGTATTAGGAGTACTAGGATTAGATAG
TGATAACATCAATGCGCAAATTGCTACTACAGGCGGTACTAAGGTCAAGTCTTCTGAGCCTCCTGTTATATTCAAAAGTA
ATATTAGTACCGTTAACAAAGCATCACAAGTTGAGGAAGCATTTGATCAGGATTACTCAAATGATAGTACAGCTCTTGAT
TTGGCTAATGTTGATAATGACGATACAACACAGAGTGAAGCTAGCAAGCTAAAAACCGAAATAAGAGATGCCAAAGCAGA
TCTTCCAGGTGATGCAGACTCTCCAGCATCAGCAGTTCAAACTCTTGCCGAGCAGGGGTAG

Upstream 100 bases:

>100_bases
AAGATGAATCTCTAAGAAAATTTTTATTAGTGTTTTGTATACTAATTTACTATAATAAGACTTGTATTTTTTTGCCAACC
TTAATATGAGAATAATTTTG

Downstream 100 bases:

>100_bases
TTTAAGTTTAGTTTTCTATATAAATATTCGAATTTATCAATCAAAACCATATTAAATTACTTAATTGTCAATATTTTTTG
TTTGTAATAATGATTAATGG

Product: putative VacJ like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKLNAKSTLLLSLLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPAANSYEKVVPDTLKSGIFNIFQNLAE
PARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYFDVADSWFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPLIGPGT
LEDITTGVDALFNPLTYIFFFAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYDYGMAK
VLKQQLSKDDATIQTDQAVLGVLGLDSDNINAQIATTGGTKVKSSEPPVIFKSNISTVNKASQVEEAFDQDYSNDSTALD
LANVDNDDTTQSEASKLKTEIRDAKADLPGDADSPASAVQTLAEQG

Sequences:

>Translated_366_residues
MKLNAKSTLLLSLLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPAANSYEKVVPDTLKSGIFNIFQNLAE
PARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYFDVADSWFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPLIGPGT
LEDITTGVDALFNPLTYIFFFAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYDYGMAK
VLKQQLSKDDATIQTDQAVLGVLGLDSDNINAQIATTGGTKVKSSEPPVIFKSNISTVNKASQVEEAFDQDYSNDSTALD
LANVDNDDTTQSEASKLKTEIRDAKADLPGDADSPASAVQTLAEQG
>Mature_366_residues
MKLNAKSTLLLSLLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPAANSYEKVVPDTLKSGIFNIFQNLAE
PARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYFDVADSWFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPLIGPGT
LEDITTGVDALFNPLTYIFFFAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYDYGMAK
VLKQQLSKDDATIQTDQAVLGVLGLDSDNINAQIATTGGTKVKSSEPPVIFKSNISTVNKASQVEEAFDQDYSNDSTALD
LANVDNDDTTQSEASKLKTEIRDAKADLPGDADSPASAVQTLAEQG

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=262, Percent_Identity=33.969465648855, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 40029; Mature: 40029

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNAKSTLLLSLLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPAANSYE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEECCCHHHHHCCCCCCHH
KVVPDTLKSGIFNIFQNLAEPARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYFDVADS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHH
WFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPLIGPGTLEDITTGVDALFNPLTYIFF
HHCCHHHHHHHHEEEEECCCCEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYDYGMAK
HHHHCHHHHCCCCCCCCCHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHH
VLKQQLSKDDATIQTDQAVLGVLGLDSDNINAQIATTGGTKVKSSEPPVIFKSNISTVNK
HHHHHHCCCCCEEEECHHHEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEECCCCHHHH
ASQVEEAFDQDYSNDSTALDLANVDNDDTTQSEASKLKTEIRDAKADLPGDADSPASAVQ
HHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
TLAEQG
HHHHCC
>Mature Secondary Structure
MKLNAKSTLLLSLLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPAANSYE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEECCCHHHHHCCCCCCHH
KVVPDTLKSGIFNIFQNLAEPARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYFDVADS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHH
WFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPLIGPGTLEDITTGVDALFNPLTYIFF
HHCCHHHHHHHHEEEEECCCCEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYDYGMAK
HHHHCHHHHCCCCCCCCCHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHH
VLKQQLSKDDATIQTDQAVLGVLGLDSDNINAQIATTGGTKVKSSEPPVIFKSNISTVNK
HHHHHHCCCCCEEEECHHHEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEECCCCHHHH
ASQVEEAFDQDYSNDSTALDLANVDNDDTTQSEASKLKTEIRDAKADLPGDADSPASAVQ
HHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
TLAEQG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]