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The map label for this gene is cysS [H]

Identifier: 134301406

GI number: 134301406

Start: 303539

End: 304933

Strand: Reverse

Name: cysS [H]

Synonym: FTW_0301

Alternate gene names: 134301406

Gene position: 304933-303539 (Counterclockwise)

Preceding gene: 134301409

Following gene: 134301405

Centisome position: 16.06

GC content: 34.91

Gene sequence:

>1395_bases
ATGGATTTTTGCTTTATGATTTTTTATAACTCTTTATCAGGACAAAAAGAACAATTTAAGCCGATTGAGGCTAATAAAAT
CAAAATGTATGCTTGTGGTGTAACAGTTTATGATGATTGTCATATTGGTCACGCTAGGACTTATATAGCTTTTGATGTGA
TCAATAGATATTTTAAGTACCGTGGTTATGATGTTACATTAGTTAGAAATATTACCGATATTGATGACAAGATTATCAAA
AGAGCTAATGAAAATGGTGAATCTACCACTGAGTTAGTTGAGAGAAATATTAAGGCAATGCACGATGTTTTTGCTAGGCT
TAATATTCTTAAACCTTCTAAAGAACCAAGAGCTACAGAAACAATTCCCGAAATGGTAGCAATGATCGAAACTTTGATTA
AGAAAGGTTATGCTTATCAAGGAGCTAATGGCGATGTCTTTTATCGCGTAACTAAATTTGCTGATTATGGTAAGTTAAGT
AAGCAAAATCTTGAGGCTCTTCAACAAGGTTCAAGAGTTGATGTGGTTGAGGAAAAAGAAAATCCAATGGATTTTGTACT
TTGGAAGATGGCAAAAGAAGGTGAGCCAGCTTGGGATTCGCCATGGGGTGCAGGTCGTCCAGGTTGGCATATAGAGTGTT
CTGCGATGTCTAAGAAACTTTTGGGCGATACTTTTGATATTCATGCTGGCGGTTCTGATCTTAGATTCCCACATCATGAG
AATGAAATAGCGCAATCAGAAGCTTGTAATGAATGTACTTTTGCAAATTATTGGCTACATTCTGGCATGGTCAAAGTAAA
TGCTGAAAAGATGTCTAAATCCTTAAACAATTTCTTTACGATAGTTGAAGTTTTAGAAGAGTATCATCCTGAAGTTGTTA
GATATTTCTTAGCCTCAACGGTATATAGAAGTGAGATTAACTACTCAAAAGAGAATCTTGAAAATGCAAAGGCTTCTGTA
GAAAGATTATTTAATGCATTAAGAGATATTGAGCCAATTGAGGTGAATCTTCCTGATGATGCTAGTGAGTATGAAGAGAA
ATTTATCAAAGCTATGGATAATGATTTTAATACTCCAGAAGCTTTAGCTGTTTTATTTAGCTTAGCTAAAGAAATAAATA
CTCTTAAGACAACAAATAAATATAAAGCTAGTGGCTATGCATATTTGTTGCGAAAGCTTTGTGATGTTTTGGGTATTTTG
TTTACTGATATTGAAGAGTATTTCAAGCAAGGTGATGGTGCGGATGCCAGTGAGATTGAGAAGCTTATAGCCGAGCGTAC
TCAAGCTAAAAAAGACAAAAATTATGCGCGTGCCGATGAGATAAGAAATCAGCTCCAACAGCAAGGAATAATATTAGAAG
ATAGTGCAACTGGTACTACATGGAAGAAAGGTTAA

Upstream 100 bases:

>100_bases
TATCTTAATATGGTTTATAAAAGCTTTGAGTAATAAGATTTTTTCCAAAAGTACTAAAATTTAGTTATACTGATAACTTA
TAATTATAAGATTCAAAAAG

Downstream 100 bases:

>100_bases
TAAATGTATAGTCAACAAAAGCAACAAGATATTATAAATAATCTACATACAATCAGAGATTATATACGTTGGTCAATTTC
AGAGATGACGGCAAACAACG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MDFCFMIFYNSLSGQKEQFKPIEANKIKMYACGVTVYDDCHIGHARTYIAFDVINRYFKYRGYDVTLVRNITDIDDKIIK
RANENGESTTELVERNIKAMHDVFARLNILKPSKEPRATETIPEMVAMIETLIKKGYAYQGANGDVFYRVTKFADYGKLS
KQNLEALQQGSRVDVVEEKENPMDFVLWKMAKEGEPAWDSPWGAGRPGWHIECSAMSKKLLGDTFDIHAGGSDLRFPHHE
NEIAQSEACNECTFANYWLHSGMVKVNAEKMSKSLNNFFTIVEVLEEYHPEVVRYFLASTVYRSEINYSKENLENAKASV
ERLFNALRDIEPIEVNLPDDASEYEEKFIKAMDNDFNTPEALAVLFSLAKEINTLKTTNKYKASGYAYLLRKLCDVLGIL
FTDIEEYFKQGDGADASEIEKLIAERTQAKKDKNYARADEIRNQLQQQGIILEDSATGTTWKKG

Sequences:

>Translated_464_residues
MDFCFMIFYNSLSGQKEQFKPIEANKIKMYACGVTVYDDCHIGHARTYIAFDVINRYFKYRGYDVTLVRNITDIDDKIIK
RANENGESTTELVERNIKAMHDVFARLNILKPSKEPRATETIPEMVAMIETLIKKGYAYQGANGDVFYRVTKFADYGKLS
KQNLEALQQGSRVDVVEEKENPMDFVLWKMAKEGEPAWDSPWGAGRPGWHIECSAMSKKLLGDTFDIHAGGSDLRFPHHE
NEIAQSEACNECTFANYWLHSGMVKVNAEKMSKSLNNFFTIVEVLEEYHPEVVRYFLASTVYRSEINYSKENLENAKASV
ERLFNALRDIEPIEVNLPDDASEYEEKFIKAMDNDFNTPEALAVLFSLAKEINTLKTTNKYKASGYAYLLRKLCDVLGIL
FTDIEEYFKQGDGADASEIEKLIAERTQAKKDKNYARADEIRNQLQQQGIILEDSATGTTWKKG
>Mature_464_residues
MDFCFMIFYNSLSGQKEQFKPIEANKIKMYACGVTVYDDCHIGHARTYIAFDVINRYFKYRGYDVTLVRNITDIDDKIIK
RANENGESTTELVERNIKAMHDVFARLNILKPSKEPRATETIPEMVAMIETLIKKGYAYQGANGDVFYRVTKFADYGKLS
KQNLEALQQGSRVDVVEEKENPMDFVLWKMAKEGEPAWDSPWGAGRPGWHIECSAMSKKLLGDTFDIHAGGSDLRFPHHE
NEIAQSEACNECTFANYWLHSGMVKVNAEKMSKSLNNFFTIVEVLEEYHPEVVRYFLASTVYRSEINYSKENLENAKASV
ERLFNALRDIEPIEVNLPDDASEYEEKFIKAMDNDFNTPEALAVLFSLAKEINTLKTTNKYKASGYAYLLRKLCDVLGIL
FTDIEEYFKQGDGADASEIEKLIAERTQAKKDKNYARADEIRNQLQQQGIILEDSATGTTWKKG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=506, Percent_Identity=35.1778656126482, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI62240992, Length=231, Percent_Identity=43.2900432900433, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI10835051, Length=231, Percent_Identity=43.2900432900433, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI303304987, Length=231, Percent_Identity=43.2900432900433, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI21269877, Length=231, Percent_Identity=43.2900432900433, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI1786737, Length=459, Percent_Identity=57.0806100217865, Blast_Score=535, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17509797, Length=231, Percent_Identity=40.6926406926407, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17509795, Length=231, Percent_Identity=40.6926406926407, Blast_Score=187, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6324082, Length=310, Percent_Identity=36.7741935483871, Blast_Score=207, Evalue=2e-54,
Organism=Drosophila melanogaster, GI19922218, Length=478, Percent_Identity=33.4728033472803, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI19922364, Length=231, Percent_Identity=43.2900432900433, Blast_Score=192, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53077; Mature: 53077

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFCFMIFYNSLSGQKEQFKPIEANKIKMYACGVTVYDDCHIGHARTYIAFDVINRYFKY
CCEEEEEEECCCCCCHHHCCCCCCCCEEEEEECEEEECCCCCCCHHHHHHHHHHHHHHHH
RGYDVTLVRNITDIDDKIIKRANENGESTTELVERNIKAMHDVFARLNILKPSKEPRATE
CCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TIPEMVAMIETLIKKGYAYQGANGDVFYRVTKFADYGKLSKQNLEALQQGSRVDVVEEKE
HHHHHHHHHHHHHHCCCEEECCCCCEEEEEEHHHHHCCCCHHHHHHHHCCCCEEEECCCC
NPMDFVLWKMAKEGEPAWDSPWGAGRPGWHIECSAMSKKLLGDTFDIHAGGSDLRFPHHE
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEECCCCCCCCCCCH
NEIAQSEACNECTFANYWLHSGMVKVNAEKMSKSLNNFFTIVEVLEEYHPEVVRYFLAST
HHHHHHHCCCCCHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYRSEINYSKENLENAKASVERLFNALRDIEPIEVNLPDDASEYEEKFIKAMDNDFNTPE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCCHH
ALAVLFSLAKEINTLKTTNKYKASGYAYLLRKLCDVLGILFTDIEEYFKQGDGADASEIE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KLIAERTQAKKDKNYARADEIRNQLQQQGIILEDSATGTTWKKG
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MDFCFMIFYNSLSGQKEQFKPIEANKIKMYACGVTVYDDCHIGHARTYIAFDVINRYFKY
CCEEEEEEECCCCCCHHHCCCCCCCCEEEEEECEEEECCCCCCCHHHHHHHHHHHHHHHH
RGYDVTLVRNITDIDDKIIKRANENGESTTELVERNIKAMHDVFARLNILKPSKEPRATE
CCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TIPEMVAMIETLIKKGYAYQGANGDVFYRVTKFADYGKLSKQNLEALQQGSRVDVVEEKE
HHHHHHHHHHHHHHCCCEEECCCCCEEEEEEHHHHHCCCCHHHHHHHHCCCCEEEECCCC
NPMDFVLWKMAKEGEPAWDSPWGAGRPGWHIECSAMSKKLLGDTFDIHAGGSDLRFPHHE
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEECCCCCCCCCCCH
NEIAQSEACNECTFANYWLHSGMVKVNAEKMSKSLNNFFTIVEVLEEYHPEVVRYFLAST
HHHHHHHCCCCCHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYRSEINYSKENLENAKASVERLFNALRDIEPIEVNLPDDASEYEEKFIKAMDNDFNTPE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCCHH
ALAVLFSLAKEINTLKTTNKYKASGYAYLLRKLCDVLGILFTDIEEYFKQGDGADASEIE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KLIAERTQAKKDKNYARADEIRNQLQQQGIILEDSATGTTWKKG
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA