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The map label for this gene is yhdP [H]

Identifier: 134301396

GI number: 134301396

Start: 292294

End: 293601

Strand: Direct

Name: yhdP [H]

Synonym: FTW_0286

Alternate gene names: 134301396

Gene position: 292294-293601 (Clockwise)

Preceding gene: 134301395

Following gene: 134301397

Centisome position: 15.4

GC content: 31.96

Gene sequence:

>1308_bases
ATGATCGGCTACAATAACATAGTTTATATAGCTATAGCCTTTGGATTTGTACTATTAAATGCTTTTTTTGTTATAGCTGA
ATTTTCATTAGTTAAGCTTAGAAGCTCGCAGGTCGAGCTTTTACGCAATAAAAAAGCACTACAAGGTAAGGTCCTCTATA
AGGTACATAATAATATTGATATCTATCTCTCTGCTTGTCAATTTGGTATTACGCTAGCATCACTAGGTTTAGGTTGGATT
GGTGAACCAGCTTTTTCTAAACTTTTGGAACCGCTTTTTATATTTCTTGGGGTTACAGCTAATCTTTCAAAATTTATTGC
TTTTGCAACTGGTTTTGCACTTATATCATTTTTGCATATAGTCATAGGTGAGCTTATGCCAAAATCTATGGCGATTAGAC
AAACTGAGAGATTATCACTACTGACATGCATTCCTTTGTATATATTTTATTGGGTGATGTTTCCTTTTATATGGATATTA
AATGCTACAGCAAATAAACTTTTAGAGCTTTTTAAGTTAGATGTAGTTGGCGAAGCTGAGTATGGCTATACTACAGATGA
GATTAAAGTGATTTTAAAAAGTAGCTATCTTAAAAAACCTCTAACGGAGGAACATCGAGATATTTTGCTGAGAATGGTTG
AGTTCGCGCATTTACATGCCATAGACGCGATGCGTCCAATCAAAGAAATGGTTTCAATAGACTATGATCTAACTAATCGT
GAAAAACTTGCGGTTATCAAAGAGTTTCTATACACAAGGTACCCAGTTTATCAAAAAGACAAAAATAACATTATTGGAGT
TGTTCATACAAAAGATATTTTATGTGCTTTAGATACAGAACTTATGAAACAAGATTTACGTCCAATTCTAAAAGTATCAT
ACCATGATCGATTAATAGATGTACTAAATAAGTTTCAACAAGGCAGACCACACTTTGCTCTAGTTTATAAGAAAAATCAA
CTTATTGGCTTTATCACTCTAGATAATCTCTTGACTATATTAATTGGTAGAATATCTGATGAATTTCATCTGGTAAAAAA
ACCATGGATTACATTAGCTAACAATAAATTTTTGATAAAGGCTGATGCTCCAGTATATGCAATAGAAAGATTAGCCGATA
TAGATTTATCAGAATATCCTGCTGATACCGTTTTAGATTTGTTACAAACTGTTTTGGCTGAGAAAATCTCTACTAATACT
ATGTGGGAGCATGATAAATTTATACTCAAAGCATATAGGGTTGATGAAGATGGCTTAAAAGATGTTATCTTGGAATTAAA
ATCATTAGATCAAATAAAATTTAACTAG

Upstream 100 bases:

>100_bases
TCTATGTACTTATTATGTATGTTGCCAAGTATTTTACTTTTCTTAAATACTATCTTATGTGTTATGGTATTAGGTAGGGC
GAAATATTAGCTAAATTATT

Downstream 100 bases:

>100_bases
CAAAAAGTGATTTAGTAAAAAAGCTATGCTACTATATTGCAACAGTTTTAATTTTGAAAAAGATTAAGTCGTGAAAGCTA
GGTTTTCTTCTACAAGTAAA

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MIGYNNIVYIAIAFGFVLLNAFFVIAEFSLVKLRSSQVELLRNKKALQGKVLYKVHNNIDIYLSACQFGITLASLGLGWI
GEPAFSKLLEPLFIFLGVTANLSKFIAFATGFALISFLHIVIGELMPKSMAIRQTERLSLLTCIPLYIFYWVMFPFIWIL
NATANKLLELFKLDVVGEAEYGYTTDEIKVILKSSYLKKPLTEEHRDILLRMVEFAHLHAIDAMRPIKEMVSIDYDLTNR
EKLAVIKEFLYTRYPVYQKDKNNIIGVVHTKDILCALDTELMKQDLRPILKVSYHDRLIDVLNKFQQGRPHFALVYKKNQ
LIGFITLDNLLTILIGRISDEFHLVKKPWITLANNKFLIKADAPVYAIERLADIDLSEYPADTVLDLLQTVLAEKISTNT
MWEHDKFILKAYRVDEDGLKDVILELKSLDQIKFN

Sequences:

>Translated_435_residues
MIGYNNIVYIAIAFGFVLLNAFFVIAEFSLVKLRSSQVELLRNKKALQGKVLYKVHNNIDIYLSACQFGITLASLGLGWI
GEPAFSKLLEPLFIFLGVTANLSKFIAFATGFALISFLHIVIGELMPKSMAIRQTERLSLLTCIPLYIFYWVMFPFIWIL
NATANKLLELFKLDVVGEAEYGYTTDEIKVILKSSYLKKPLTEEHRDILLRMVEFAHLHAIDAMRPIKEMVSIDYDLTNR
EKLAVIKEFLYTRYPVYQKDKNNIIGVVHTKDILCALDTELMKQDLRPILKVSYHDRLIDVLNKFQQGRPHFALVYKKNQ
LIGFITLDNLLTILIGRISDEFHLVKKPWITLANNKFLIKADAPVYAIERLADIDLSEYPADTVLDLLQTVLAEKISTNT
MWEHDKFILKAYRVDEDGLKDVILELKSLDQIKFN
>Mature_435_residues
MIGYNNIVYIAIAFGFVLLNAFFVIAEFSLVKLRSSQVELLRNKKALQGKVLYKVHNNIDIYLSACQFGITLASLGLGWI
GEPAFSKLLEPLFIFLGVTANLSKFIAFATGFALISFLHIVIGELMPKSMAIRQTERLSLLTCIPLYIFYWVMFPFIWIL
NATANKLLELFKLDVVGEAEYGYTTDEIKVILKSSYLKKPLTEEHRDILLRMVEFAHLHAIDAMRPIKEMVSIDYDLTNR
EKLAVIKEFLYTRYPVYQKDKNNIIGVVHTKDILCALDTELMKQDLRPILKVSYHDRLIDVLNKFQQGRPHFALVYKKNQ
LIGFITLDNLLTILIGRISDEFHLVKKPWITLANNKFLIKADAPVYAIERLADIDLSEYPADTVLDLLQTVLAEKISTNT
MWEHDKFILKAYRVDEDGLKDVILELKSLDQIKFN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=329, Percent_Identity=34.6504559270517, Blast_Score=207, Evalue=1e-53,
Organism=Escherichia coli, GI1790664, Length=380, Percent_Identity=23.6842105263158, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1786879, Length=156, Percent_Identity=28.8461538461538, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI145693175, Length=325, Percent_Identity=22.1538461538462, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50022; Mature: 50022

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGYNNIVYIAIAFGFVLLNAFFVIAEFSLVKLRSSQVELLRNKKALQGKVLYKVHNNID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCEE
IYLSACQFGITLASLGLGWIGEPAFSKLLEPLFIFLGVTANLSKFIAFATGFALISFLHI
EEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGELMPKSMAIRQTERLSLLTCIPLYIFYWVMFPFIWILNATANKLLELFKLDVVGEAE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
YGYTTDEIKVILKSSYLKKPLTEEHRDILLRMVEFAHLHAIDAMRPIKEMVSIDYDLTNR
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EKLAVIKEFLYTRYPVYQKDKNNIIGVVHTKDILCALDTELMKQDLRPILKVSYHDRLID
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLNKFQQGRPHFALVYKKNQLIGFITLDNLLTILIGRISDEFHLVKKPWITLANNKFLIK
HHHHHHCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHCCCCHHEEECCCEEEECCEEEEE
ADAPVYAIERLADIDLSEYPADTVLDLLQTVLAEKISTNTMWEHDKFILKAYRVDEDGLK
ECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEECCCCCHH
DVILELKSLDQIKFN
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MIGYNNIVYIAIAFGFVLLNAFFVIAEFSLVKLRSSQVELLRNKKALQGKVLYKVHNNID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCEE
IYLSACQFGITLASLGLGWIGEPAFSKLLEPLFIFLGVTANLSKFIAFATGFALISFLHI
EEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGELMPKSMAIRQTERLSLLTCIPLYIFYWVMFPFIWILNATANKLLELFKLDVVGEAE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
YGYTTDEIKVILKSSYLKKPLTEEHRDILLRMVEFAHLHAIDAMRPIKEMVSIDYDLTNR
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EKLAVIKEFLYTRYPVYQKDKNNIIGVVHTKDILCALDTELMKQDLRPILKVSYHDRLID
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLNKFQQGRPHFALVYKKNQLIGFITLDNLLTILIGRISDEFHLVKKPWITLANNKFLIK
HHHHHHCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHCCCCHHEEECCCEEEECCEEEEE
ADAPVYAIERLADIDLSEYPADTVLDLLQTVLAEKISTNTMWEHDKFILKAYRVDEDGLK
ECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEECCCCCHH
DVILELKSLDQIKFN
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]