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The map label for this gene is ftsK [H]

Identifier: 134301389

GI number: 134301389

Start: 282115

End: 284616

Strand: Reverse

Name: ftsK [H]

Synonym: FTW_0279

Alternate gene names: 134301389

Gene position: 284616-282115 (Counterclockwise)

Preceding gene: 134301404

Following gene: 134301388

Centisome position: 14.99

GC content: 36.77

Gene sequence:

>2502_bases
ATGACAGATAACAACATAAACAAAACAAGTCATGCAGTTGGTAGATTAAAAATAACTCTAGTAGTTATTTTAACAGCTAG
CATAATATATCTTTTTATCGCCTTATTTAGCTTTAATATTAATGACCCAGGCTGGAGTAGTGTTTCATCTGAAACCACAA
TAAAAAATTACGCCGGACCCGTTGGTGCATACATAGCAAGTTTTATACTTTCAATATTTGGTGTTATCGGCTTTATTTTA
CCTTTTTTACTTATTGATTTTGTCAGAATCCTCCTAATCAAACGCAAACAACAAAGTCTTAGCTATCTTTTATTTACAGT
GAAGACTATTGGAATTATTGTTTTCATACTATCTTGCTGTGGGCTTGCTGAGCTTTATCTTAGTTTTGCTAACTACTGGG
TGCCTCAACGCTCTGGTGGTATTCTAGGTTATGAATCAGTCAAACTCACAATCAAATATTTAGGCTCAGTAGGTGGTAAC
TTTGCATTATTAATAGCATTGTTAGTAGGTCTAACGCTGTATTCAGGCACAACATGGATATATCTATTCAAAAACTTAGC
GATATTTGTTGCCAAAGTGTTTACTTATATCACAAAATCAAAAACTAATGATAATAAAAATATCCCAGATATAAATGGCT
TTGAAAATTTTGAAAGCAAAAATAACCTAACAAGTCCACTTAATAGAGATAATAAAGTAGTCTCAAGTATCTTTGAAGAT
AACCAACAAACTCATAAAAAAGATATTTTCAGAGAAGTTTTAGACAATACAAAAGTTACAAATGAACTTTCATTTAGAGA
TCCTAAAACTGAATCCCCACAAAACTCAGATTTAGAAATAGTATCAGATTCAGATTCAATCTTAGACCTAGATGTATTAG
ATGAAGATATCGATTTAGACTCTGAATTATCATCACAATCGGATAATGAGAGTAAACCCGCGATGACAAAAGAGCAACTA
AAAGGGATCACAACAGTGTCGTCTCCAATAAGCTCAAGTGCCAGTAAAGCTCTCAATAAAAAAATGCTACCGTCTTTAGA
TCTACTTATAGAACCAGAAGCAAAACAAACTGTTATTTCTCAAGCACAGCTTGATGAGACATCTTCATTACTTGAACAAA
CTCTAAATGACTTCAATATTAATGCAAAAGTAGTTGCAGCATATCCAGGTCCGGTAATCACAAGGTATGAGATAGACCTT
GCAAGGGGTACAAAGGTTAGCAAACTTACAAATATTGCCCAAGATTTAGCTAGAGCTCTATCTACTACCGCGGTTAGAGT
TGTTGAGGTAATTCCTGGTAAACCGTACGTAGGCTTAGAACTACCTAATCCAACTAGACAAATGGTGAGAATTAAAGAAG
TGCTAGCAGCTCCGGAGTTTGTCAAATCTAAAGCCCCTACCCTAATGGGAATAGGTGTCGATATATCTGGTAAACCGACA
TTTGCAGAACTTGCAAAAATGCCTCATCTTTTAGTAGCTGGTACAACAGGTTCAGGTAAATCTGTTGGTGTCAATGCAAT
GATTCTTAGTATGCTATACAAGTGTAGTCCTGATGAGCTCAAATTTATCATGATTGATCCAAAGATGCTTGAGCTTTCAA
TCTATGATGGTATACCACACTTATTGACTCCAGTTGTCACAGATATGACAGAGGCTGCGAACTCTTTGCGTTGGTGTGTC
AAAGAGATGGAACGTCGCTATGCCTTAATGTCAGCTGCTGGAGTGAGAAATATTGCCTTACTTAATGATAAGATTGAACA
AGCAGAGAAAGTTGGTAGACCTCTCAAAGATACGATGTTTATCAAGATGAATCCAGAAAGAGCGCATGAAGCACCATTAC
TTACAAAAATGCCATACATCGTTGTTGTCGCAGATGAGTTTGCCGATATGATTATGGTTGTTGGTAAAAAGGTTGAGGAG
TTAATCGCTAGACTTGCTCAAAAAGCGCGTGCAGCTGGTATTCATATAATTCTAGCAACACAAAGACCATCCGTTGATGT
TGTAACTGGATTAATAAAGGCAAATATCCCAACAAGAATGTCTTTTCAGGTGTCATCTAGAATTGACTCTAGGACAATAC
TCGATCAGCAAGGCGCTGAGCAACTTCTAGGACAAGGTGACATGCTGTATCTTAAACCAGGCTTTGGTGCTCCTATGCGT
ATTCATGGTGCTTTTGTTGATGATAACGAAGTACATAGAGTAGTAGAAGCTTGGAAAGAATATGGTGAGCCAGAATATGT
TCAAGACATTTTAGAAGCAGCGGAAGAATCTGAAAATGGTGGTAGCCCAAGTAACAGTGGTGACAGCGAAGACCCTCTCT
ATAACGAAGCAGTAGAGATCGTTATCAAAACCCAAAAAGCCTCAATCTCTGCGGTACAACGTAAGCTAAAAATAGGCTAT
AACCGTTCAGCACGATTGATGGAAGAAATGGAAGAAAATGGTATTGTTTCAGAGATGAATCAAAATGGAATGCGTGAAGT
TCTAATAAAGAGAGACTCTTAA

Upstream 100 bases:

>100_bases
AAGCTTAATAAATTAGTAGTATAGTCTAACATTTTTAGAGTTTTTTTTGTTAAAATTGTCAATTGGTTTTACTTATTAAA
CATAAATATTTTAGAAAAAT

Downstream 100 bases:

>100_bases
ATGAAAAAGATAATTATATGTTTTATATTTGTTTTTAGTATCAATGTTAGCTTTGCTGATGCCACTAGCGAGCTTATAGA
CAAGATAAAAAATATCCACT

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 833; Mature: 832

Protein sequence:

>833_residues
MTDNNINKTSHAVGRLKITLVVILTASIIYLFIALFSFNINDPGWSSVSSETTIKNYAGPVGAYIASFILSIFGVIGFIL
PFLLIDFVRILLIKRKQQSLSYLLFTVKTIGIIVFILSCCGLAELYLSFANYWVPQRSGGILGYESVKLTIKYLGSVGGN
FALLIALLVGLTLYSGTTWIYLFKNLAIFVAKVFTYITKSKTNDNKNIPDINGFENFESKNNLTSPLNRDNKVVSSIFED
NQQTHKKDIFREVLDNTKVTNELSFRDPKTESPQNSDLEIVSDSDSILDLDVLDEDIDLDSELSSQSDNESKPAMTKEQL
KGITTVSSPISSSASKALNKKMLPSLDLLIEPEAKQTVISQAQLDETSSLLEQTLNDFNINAKVVAAYPGPVITRYEIDL
ARGTKVSKLTNIAQDLARALSTTAVRVVEVIPGKPYVGLELPNPTRQMVRIKEVLAAPEFVKSKAPTLMGIGVDISGKPT
FAELAKMPHLLVAGTTGSGKSVGVNAMILSMLYKCSPDELKFIMIDPKMLELSIYDGIPHLLTPVVTDMTEAANSLRWCV
KEMERRYALMSAAGVRNIALLNDKIEQAEKVGRPLKDTMFIKMNPERAHEAPLLTKMPYIVVVADEFADMIMVVGKKVEE
LIARLAQKARAAGIHIILATQRPSVDVVTGLIKANIPTRMSFQVSSRIDSRTILDQQGAEQLLGQGDMLYLKPGFGAPMR
IHGAFVDDNEVHRVVEAWKEYGEPEYVQDILEAAEESENGGSPSNSGDSEDPLYNEAVEIVIKTQKASISAVQRKLKIGY
NRSARLMEEMEENGIVSEMNQNGMREVLIKRDS

Sequences:

>Translated_833_residues
MTDNNINKTSHAVGRLKITLVVILTASIIYLFIALFSFNINDPGWSSVSSETTIKNYAGPVGAYIASFILSIFGVIGFIL
PFLLIDFVRILLIKRKQQSLSYLLFTVKTIGIIVFILSCCGLAELYLSFANYWVPQRSGGILGYESVKLTIKYLGSVGGN
FALLIALLVGLTLYSGTTWIYLFKNLAIFVAKVFTYITKSKTNDNKNIPDINGFENFESKNNLTSPLNRDNKVVSSIFED
NQQTHKKDIFREVLDNTKVTNELSFRDPKTESPQNSDLEIVSDSDSILDLDVLDEDIDLDSELSSQSDNESKPAMTKEQL
KGITTVSSPISSSASKALNKKMLPSLDLLIEPEAKQTVISQAQLDETSSLLEQTLNDFNINAKVVAAYPGPVITRYEIDL
ARGTKVSKLTNIAQDLARALSTTAVRVVEVIPGKPYVGLELPNPTRQMVRIKEVLAAPEFVKSKAPTLMGIGVDISGKPT
FAELAKMPHLLVAGTTGSGKSVGVNAMILSMLYKCSPDELKFIMIDPKMLELSIYDGIPHLLTPVVTDMTEAANSLRWCV
KEMERRYALMSAAGVRNIALLNDKIEQAEKVGRPLKDTMFIKMNPERAHEAPLLTKMPYIVVVADEFADMIMVVGKKVEE
LIARLAQKARAAGIHIILATQRPSVDVVTGLIKANIPTRMSFQVSSRIDSRTILDQQGAEQLLGQGDMLYLKPGFGAPMR
IHGAFVDDNEVHRVVEAWKEYGEPEYVQDILEAAEESENGGSPSNSGDSEDPLYNEAVEIVIKTQKASISAVQRKLKIGY
NRSARLMEEMEENGIVSEMNQNGMREVLIKRDS
>Mature_832_residues
TDNNINKTSHAVGRLKITLVVILTASIIYLFIALFSFNINDPGWSSVSSETTIKNYAGPVGAYIASFILSIFGVIGFILP
FLLIDFVRILLIKRKQQSLSYLLFTVKTIGIIVFILSCCGLAELYLSFANYWVPQRSGGILGYESVKLTIKYLGSVGGNF
ALLIALLVGLTLYSGTTWIYLFKNLAIFVAKVFTYITKSKTNDNKNIPDINGFENFESKNNLTSPLNRDNKVVSSIFEDN
QQTHKKDIFREVLDNTKVTNELSFRDPKTESPQNSDLEIVSDSDSILDLDVLDEDIDLDSELSSQSDNESKPAMTKEQLK
GITTVSSPISSSASKALNKKMLPSLDLLIEPEAKQTVISQAQLDETSSLLEQTLNDFNINAKVVAAYPGPVITRYEIDLA
RGTKVSKLTNIAQDLARALSTTAVRVVEVIPGKPYVGLELPNPTRQMVRIKEVLAAPEFVKSKAPTLMGIGVDISGKPTF
AELAKMPHLLVAGTTGSGKSVGVNAMILSMLYKCSPDELKFIMIDPKMLELSIYDGIPHLLTPVVTDMTEAANSLRWCVK
EMERRYALMSAAGVRNIALLNDKIEQAEKVGRPLKDTMFIKMNPERAHEAPLLTKMPYIVVVADEFADMIMVVGKKVEEL
IARLAQKARAAGIHIILATQRPSVDVVTGLIKANIPTRMSFQVSSRIDSRTILDQQGAEQLLGQGDMLYLKPGFGAPMRI
HGAFVDDNEVHRVVEAWKEYGEPEYVQDILEAAEESENGGSPSNSGDSEDPLYNEAVEIVIKTQKASISAVQRKLKIGYN
RSARLMEEMEENGIVSEMNQNGMREVLIKRDS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=496, Percent_Identity=61.2903225806452, Blast_Score=607, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 91932; Mature: 91801

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00589 PTS_HPR_SER ; PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNNINKTSHAVGRLKITLVVILTASIIYLFIALFSFNINDPGWSSVSSETTIKNYAGP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCH
VGAYIASFILSIFGVIGFILPFLLIDFVRILLIKRKQQSLSYLLFTVKTIGIIVFILSCC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAELYLSFANYWVPQRSGGILGYESVKLTIKYLGSVGGNFALLIALLVGLTLYSGTTWI
HHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHH
YLFKNLAIFVAKVFTYITKSKTNDNKNIPDINGFENFESKNNLTSPLNRDNKVVSSIFED
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
NQQTHKKDIFREVLDNTKVTNELSFRDPKTESPQNSDLEIVSDSDSILDLDVLDEDIDLD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCC
SELSSQSDNESKPAMTKEQLKGITTVSSPISSSASKALNKKMLPSLDLLIEPEAKQTVIS
HHHCCCCCCCCCCCCCHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHH
QAQLDETSSLLEQTLNDFNINAKVVAAYPGPVITRYEIDLARGTKVSKLTNIAQDLARAL
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
STTAVRVVEVIPGKPYVGLELPNPTRQMVRIKEVLAAPEFVKSKAPTLMGIGVDISGKPT
HHHHHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHCHHHHHCCCCEEEEEEECCCCCCC
FAELAKMPHLLVAGTTGSGKSVGVNAMILSMLYKCSPDELKFIMIDPKMLELSIYDGIPH
HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCHH
LLTPVVTDMTEAANSLRWCVKEMERRYALMSAAGVRNIALLNDKIEQAEKVGRPLKDTMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEE
IKMNPERAHEAPLLTKMPYIVVVADEFADMIMVVGKKVEELIARLAQKARAAGIHIILAT
EEECHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
QRPSVDVVTGLIKANIPTRMSFQVSSRIDSRTILDQQGAEQLLGQGDMLYLKPGFGAPMR
CCCCHHHHHHHHHCCCCCCEEEEHHHCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEE
IHGAFVDDNEVHRVVEAWKEYGEPEYVQDILEAAEESENGGSPSNSGDSEDPLYNEAVEI
EEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHE
VIKTQKASISAVQRKLKIGYNRSARLMEEMEENGIVSEMNQNGMREVLIKRDS
EEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHEECCC
>Mature Secondary Structure 
TDNNINKTSHAVGRLKITLVVILTASIIYLFIALFSFNINDPGWSSVSSETTIKNYAGP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCH
VGAYIASFILSIFGVIGFILPFLLIDFVRILLIKRKQQSLSYLLFTVKTIGIIVFILSCC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAELYLSFANYWVPQRSGGILGYESVKLTIKYLGSVGGNFALLIALLVGLTLYSGTTWI
HHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHH
YLFKNLAIFVAKVFTYITKSKTNDNKNIPDINGFENFESKNNLTSPLNRDNKVVSSIFED
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
NQQTHKKDIFREVLDNTKVTNELSFRDPKTESPQNSDLEIVSDSDSILDLDVLDEDIDLD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCC
SELSSQSDNESKPAMTKEQLKGITTVSSPISSSASKALNKKMLPSLDLLIEPEAKQTVIS
HHHCCCCCCCCCCCCCHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHH
QAQLDETSSLLEQTLNDFNINAKVVAAYPGPVITRYEIDLARGTKVSKLTNIAQDLARAL
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
STTAVRVVEVIPGKPYVGLELPNPTRQMVRIKEVLAAPEFVKSKAPTLMGIGVDISGKPT
HHHHHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHCHHHHHCCCCEEEEEEECCCCCCC
FAELAKMPHLLVAGTTGSGKSVGVNAMILSMLYKCSPDELKFIMIDPKMLELSIYDGIPH
HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCHH
LLTPVVTDMTEAANSLRWCVKEMERRYALMSAAGVRNIALLNDKIEQAEKVGRPLKDTMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEE
IKMNPERAHEAPLLTKMPYIVVVADEFADMIMVVGKKVEELIARLAQKARAAGIHIILAT
EEECHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
QRPSVDVVTGLIKANIPTRMSFQVSSRIDSRTILDQQGAEQLLGQGDMLYLKPGFGAPMR
CCCCHHHHHHHHHCCCCCCEEEEHHHCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEE
IHGAFVDDNEVHRVVEAWKEYGEPEYVQDILEAAEESENGGSPSNSGDSEDPLYNEAVEI
EEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHE
VIKTQKASISAVQRKLKIGYNRSARLMEEMEENGIVSEMNQNGMREVLIKRDS
EEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]