Click here to switch to the map view.

The map label for this gene is lolA [H]

Identifier: 134301388

GI number: 134301388

Start: 281497

End: 282114

Strand: Reverse

Name: lolA [H]

Synonym: FTW_0278

Alternate gene names: 134301388

Gene position: 282114-281497 (Counterclockwise)

Preceding gene: 134301389

Following gene: 134301386

Centisome position: 14.86

GC content: 27.83

Gene sequence:

>618_bases
ATGAAAAAGATAATTATATGTTTTATATTTGTTTTTAGTATCAATGTTAGCTTTGCTGATGCCACTAGCGAGCTTATAGA
CAAGATAAAAAATATCCACTCGATGACTGCTAACTTCAATCAAAAGCTCATAGATGGACAAACCAACAATAATCTTAACT
CAAAGGGCAATATGAGCCTTAAAAAACCACAATATTTTAAATGGATAACAACATCTCCAAATAACCAAGAAATTGTCTCT
AATGGTACAAAACTATGGATTTATGATGGTGATTTAGATCAACTTATCATAAAAAAAGTTTCTAATGACATAGCTCAATT
TCCTTATCTGATTCTTTTATCAAAAAATACCAATAACATCAATAAACTTTTTACTGTCACAGCGCAAGATAACAACAGCT
ATATTCTAAAACCTAAAAATGATCAAATGATCGATAGTATAAAAATTAAATTTACTCCAAATAACCAACTTGAGTATTTA
GAGATTTCAACTTCACTAAATCAGTTCACAAAAATTGAGTTTAATAATGTAAAAACTGATGTAGATATAAGTAATACAAG
TTTTGATTTCAAAGCGCCTCAAAATACAGATATAATTGATGAAACTAAATCCGCATAA

Upstream 100 bases:

>100_bases
CCGTTCAGCACGATTGATGGAAGAAATGGAAGAAAATGGTATTGTTTCAGAGATGAATCAAAATGGAATGCGTGAAGTTC
TAATAAAGAGAGACTCTTAA

Downstream 100 bases:

>100_bases
ATATTTTTATTATTAACTACTTTTTCTCAACCATATAAGCGCCAGTAGCTCCTCCAGCAGCACCAATACCAGCAACAGCT
AACCAGATGCAACTATTTAG

Product: lipoprotein releasing system, subunit A, outer membrane lipoproteins carrier

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKKIIICFIFVFSINVSFADATSELIDKIKNIHSMTANFNQKLIDGQTNNNLNSKGNMSLKKPQYFKWITTSPNNQEIVS
NGTKLWIYDGDLDQLIIKKVSNDIAQFPYLILLSKNTNNINKLFTVTAQDNNSYILKPKNDQMIDSIKIKFTPNNQLEYL
EISTSLNQFTKIEFNNVKTDVDISNTSFDFKAPQNTDIIDETKSA

Sequences:

>Translated_205_residues
MKKIIICFIFVFSINVSFADATSELIDKIKNIHSMTANFNQKLIDGQTNNNLNSKGNMSLKKPQYFKWITTSPNNQEIVS
NGTKLWIYDGDLDQLIIKKVSNDIAQFPYLILLSKNTNNINKLFTVTAQDNNSYILKPKNDQMIDSIKIKFTPNNQLEYL
EISTSLNQFTKIEFNNVKTDVDISNTSFDFKAPQNTDIIDETKSA
>Mature_205_residues
MKKIIICFIFVFSINVSFADATSELIDKIKNIHSMTANFNQKLIDGQTNNNLNSKGNMSLKKPQYFKWITTSPNNQEIVS
NGTKLWIYDGDLDQLIIKKVSNDIAQFPYLILLSKNTNNINKLFTVTAQDNNSYILKPKNDQMIDSIKIKFTPNNQLEYL
EISTSLNQFTKIEFNNVKTDVDISNTSFDFKAPQNTDIIDETKSA

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=217, Percent_Identity=23.963133640553, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 23436; Mature: 23436

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIICFIFVFSINVSFADATSELIDKIKNIHSMTANFNQKLIDGQTNNNLNSKGNMSL
CCCEEEEEEEEHHCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCC
KKPQYFKWITTSPNNQEIVSNGTKLWIYDGDLDQLIIKKVSNDIAQFPYLILLSKNTNNI
CCCCEEEEEECCCCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCCCCC
NKLFTVTAQDNNSYILKPKNDQMIDSIKIKFTPNNQLEYLEISTSLNQFTKIEFNNVKTD
EEEEEEEEECCCEEEEECCCCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCEEE
VDISNTSFDFKAPQNTDIIDETKSA
EEECCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKKIIICFIFVFSINVSFADATSELIDKIKNIHSMTANFNQKLIDGQTNNNLNSKGNMSL
CCCEEEEEEEEHHCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCC
KKPQYFKWITTSPNNQEIVSNGTKLWIYDGDLDQLIIKKVSNDIAQFPYLILLSKNTNNI
CCCCEEEEEECCCCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCCCCC
NKLFTVTAQDNNSYILKPKNDQMIDSIKIKFTPNNQLEYLEISTSLNQFTKIEFNNVKTD
EEEEEEEEECCCEEEEECCCCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCEEE
VDISNTSFDFKAPQNTDIIDETKSA
EEECCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA